KEGG   ORTHOLOGY: K16015Help
Entry
K16015                      KO                                     

Name
rifL, asm44
Definition
oxidoreductase [EC:1.1.1.-]
Pathway
ko01051  Biosynthesis of ansamycins
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01051 Biosynthesis of ansamycins
    K16015  rifL, asm44; oxidoreductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.-  
     K16015  rifL, asm44; oxidoreductase
BRITE hierarchy
Other DBs
RN: R06594
Genes
SVL: Strvi_5369
SRC: M271_45555
FRA: Francci3_0430
FRE: Franean1_1660 Franean1_4840
FAL: FRAAL0915
SEN: SACE_2871(rifL)
AMD: AMED_0628(rifL)
AMN: RAM_03210
AMM: AMES_0626(rifL)
AMZ: B737_0627(rifL)
AMI: Amir_3288
SAQ: Sare_1256
MIL: ML5_5913
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Yu TW, Muller R, Muller M, Zhang X, Draeger G, Kim CG, Leistner E, Floss HG
  Title
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.
  Journal
J Biol Chem 276:12546-55 (2001)
DOI:10.1074/jbc.M009667200
Reference
  Authors
Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG
  Title
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.
  Journal
Proc Natl Acad Sci U S A 99:7968-73 (2002)
DOI:10.1073/pnas.092697199

KEGG   REACTION: R06594Help
Entry
R06594                      Reaction                               

Name
UDP-glucose:NAD+ 3-oxidoreductase
Definition
UDP-glucose + NAD+ <=> UDP-3-ketoglucose + NADH + H+
Equation
Reaction class
RC00001  C00003_C00004
RC00182  C00029_C12210
Enzyme
1.1.1.-
Pathway
rn00524  Neomycin, kanamycin and gentamicin biosynthesis
rn01051  Biosynthesis of ansamycins
rn01130  Biosynthesis of antibiotics
Orthology
K16015  oxidoreductase [EC:1.1.1.-]
K20571  dehydrogenase [EC:1.1.1.-]
Other DBs
RHEA: 35758

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