KEGG   ORTHOLOGY: K16019Help
Entry
K16019                      KO                                     

Name
rifH
Definition
3,4-Dideoxy-4-amino-D-arabino-heptulosonate 7-phosphate synthase
Pathway
ko01051  Biosynthesis of ansamycins
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01051 Biosynthesis of ansamycins
    K16019  rifH; 3,4-Dideoxy-4-amino-D-arabino-heptulosonate 7-phosphate synthase
BRITE hierarchy
Other DBs
RN: R06591
Genes
AMD: AMED_0625(rifH)
AMN: RAM_03195
AMM: AMES_0623(rifH)
AMZ: B737_0624(rifH)
SAQ: Sare_1254
TaxonomyKoalaUniProt
Reference
  Authors
Yu TW, Muller R, Muller M, Zhang X, Draeger G, Kim CG, Leistner E, Floss HG
  Title
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.
  Journal
J Biol Chem 276:12546-55 (2001)
DOI:10.1074/jbc.M009667200
Reference
  Authors
Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG
  Title
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.
  Journal
Proc Natl Acad Sci U S A 99:7968-73 (2002)
DOI:10.1073/pnas.092697199

KEGG   REACTION: R06591Help
Entry
R06591                      Reaction                               

Name
phosphoenolpyruvate:imino-D-erythrose-4-phosphate C-(1-carboxyvinyl)transferase (phosphate hydrolysing, 2-carboxy-2-oxoethyl-forming)
Definition
Iminoerythrose 4-phosphate + Phosphoenolpyruvate + H2O <=> AminoDAHP + Orthophosphate
Equation
Comment
aminoDAHP synthase, RifH
Reaction class
RC01556  C12106_C12215
Pathway
rn01051  Biosynthesis of ansamycins
rn01130  Biosynthesis of antibiotics
Orthology
K16019  3,4-Dideoxy-4-amino-D-arabino-heptulosonate 7-phosphate synthase

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