KEGG   ORTHOLOGY: K16034Help
Entry
K16034                      KO                                     

Name
asm7
Definition
20-O-methyltransferase
Pathway
ko01051  Biosynthesis of ansamycins
ko01052  Type I polyketide structures
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16034  asm7; 20-O-methyltransferase
   01051 Biosynthesis of ansamycins
    K16034  asm7; 20-O-methyltransferase
BRITE hierarchy
Other DBs
RN: R09852
Genes
AMI: Amir_3177
TaxonomyKoalaUniProt
Reference
  Authors
Spiteller P, Bai L, Shang G, Carroll BJ, Yu TW, Floss HG
  Title
The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum.
  Journal
J Am Chem Soc 125:14236-7 (2003)
DOI:10.1021/ja038166y
Reference
  Authors
Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG
  Title
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.
  Journal
Proc Natl Acad Sci U S A 99:7968-73 (2002)
DOI:10.1073/pnas.092697199

KEGG   REACTION: R09852Help
Entry
R09852                      Reaction                               

Definition
19-Chloroproansamitocin <=> 20-O-Methyl-19-chloroproansamitocin
Equation
Reaction class
RC00392  C20134_C20135
Pathway
rn01051  Biosynthesis of ansamycins
rn01130  Biosynthesis of antibiotics
Orthology
K16034  20-O-methyltransferase

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