KEGG   ORTHOLOGY: K16037Help
Entry
K16037                      KO                                     

Name
asm11
Definition
4,5-epoxidase
Pathway
ko01051  Biosynthesis of ansamycins
ko01052  Type I polyketide structures
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16037  asm11; 4,5-epoxidase
   01051 Biosynthesis of ansamycins
    K16037  asm11; 4,5-epoxidase
BRITE hierarchy
Other DBs
RN: R09855
Genes
MSM: MSMEG_1499
MSG: MSMEI_1463
MSB: LJ00_07490
MSN: LI99_07490
MSH: LI98_07490
MVA: Mvan_0779
MGI: Mflv_5009
MSP: Mspyr1_44270
SEN: SACE_6588
AJA: AJAP_13725
AMI: Amir_3183
KAL: KALB_8622
SNA: Snas_6034
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Spiteller P, Bai L, Shang G, Carroll BJ, Yu TW, Floss HG
  Title
The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum.
  Journal
J Am Chem Soc 125:14236-7 (2003)
DOI:10.1021/ja038166y
Reference
  Authors
Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG
  Title
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.
  Journal
Proc Natl Acad Sci U S A 99:7968-73 (2002)
DOI:10.1073/pnas.092697199

KEGG   REACTION: R09855Help
Entry
R09855                      Reaction                               

Definition
N-Demethyl-desepoxyansamitocin P-3 <=> N-Demethylansamitocin P-3
Equation
Reaction class
RC02841  C20137_C20138
Pathway
rn01051  Biosynthesis of ansamycins
rn01130  Biosynthesis of antibiotics
Orthology
K16037  4,5-epoxidase

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