KEGG   ORTHOLOGY: K16045
Entry
K16045                      KO                                     
Symbol
hsd
Name
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:1.1.1.145 5.3.3.1]
Pathway
map00984  Steroid degradation
map01120  Microbial metabolism in diverse environments
Reaction
R09920  cholesterol:NAD+ 3-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00984 Steroid degradation
    K16045  hsd; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.145  3beta-hydroxy-Delta5-steroid dehydrogenase
     K16045  hsd; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.3  Transposing C=C bonds
    5.3.3.1  steroid Delta-isomerase
     K16045  hsd; 3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase
Other DBs
COG: COG0451
GO: 0003854 0004769
Genes
ENW: MJO57_19210
EMP: EZMO1_1200(nsdHL)
PWU: A8O14_06055
MTU: Rv1106c
MTV: RVBD_1106c
MTC: MT1137
MRA: MRA_1117
MTF: TBFG_11128
MTB: TBMG_02877
MTK: TBSG_02893
MTZ: TBXG_002857
MTG: MRGA327_06925
MTI: MRGA423_06915
MTE: CCDC5079_1022
MTUR: CFBS_1174
MTL: CCDC5180_1014
MTO: MTCTRI2_1136
MTD: UDA_1106c
MTN: ERDMAN_1239
MTJ: J112_05975
MTUB: MT7199_1133
MTUC: J113_07785
MTUE: J114_05980
MTX: M943_05820
MTUH: I917_07855
MTUL: TBHG_01091
MTUT: HKBT1_1172
MTUU: HKBT2_1178
MTQ: HKBS1_1174
MBO: BQ2027_MB1136C
MBB: BCG_1166c
MBT: JTY_1139
MBM: BCGMEX_1138c
MBK: K60_011910
MBX: BCGT_0934
MAF: MAF_11210
MMIC: RN08_1242
MCE: MCAN_11161
MCQ: BN44_11231
MCV: BN43_30163
MCX: BN42_20954
MCZ: BN45_30150
MORY: MO_001188
MLE: ML1942
MLB: MLBr01942
MPA: MAP_2688
MAO: MAP4_1128
MAVI: RC58_05605
MAVU: RE97_05600
MAV: MAV_1225
MIT: OCO_11340
MIA: OCU_11320
MID: MIP_01824
MYO: OEM_11450
MCHI: AN480_06750
MIR: OCQ_11350
MMAL: CKJ54_05520
MLP: MLM_1173
MMAN: MMAN_54580
MSER: MTY59_30480
MSA: Mycsm_05045
MUL: MUL_0172
MMI: MMAR_4359
MMAE: MMARE11_41790
MLI: MULP_04570
MPSE: MPSD_44990
MSHO: MSHO_16920
MMC: Mmcs_4109
MKM: Mkms_4185
MJL: Mjls_4340
MMM: W7S_05545
MKN: MKAN_07985
MYV: G155_22700
MYE: AB431_06460
MHAD: B586_07090
MDX: BTO20_08365
MSHG: MSG_03923
MFJ: MFLOJ_47450
MSTO: MSTO_51430
MSIM: MSIM_37390
MSAK: MSAS_22240
MKU: I2456_20620
MLW: MJO58_21440
MXE: MYXE_14010
MNV: MNVI_06140
MPAG: C0J29_23965
MNM: MNVM_07790
MGOR: H0P51_22240
MCOO: MCOO_20360
MBAI: MB901379_03818
MSEO: MSEO_27010
MHEK: JMUB5695_01344
MGAU: MGALJ_31210
MLJ: MLAC_06830
MBRD: MBRA_27460
MSHJ: MSHI_03080
MMAM: K3U93_19010
MSPG: F6B93_17425
MOT: LTS72_03400
MLM: MLPF_2463(hsd)
MPAA: MKK62_05735
MKY: IWGMT90018_50180
MADI: A7U43_09340
MWU: PT015_11765
MYW: BVC93_17935
MSM: MSMEG_5228
MSG: MSMEI_5091
MSB: LJ00_25860
MSN: LI99_25865
MSH: LI98_25870
MVA: Mvan_4635
MGI: Mflv_2075
MSP: Mspyr1_14990
MCB: Mycch_4050
MNE: D174_21420
MYN: MyAD_21005
MFT: XA26_46570
MPHL: MPHLCCUG_04229
MVQ: MYVA_4444
MLL: B1R94_06430
MRH: MycrhN_3550
MTHN: 4412656_03537
MHAS: MHAS_03213
MDU: MDUV_00690
MCHT: MCHIJ_25440
MAUU: NCTC10437_04362
MMAG: MMAD_42700
MMOR: MMOR_18320
MFX: MFAL_37920
MAIC: MAIC_43720
MIJ: MINS_38420
MALV: MALV_48580
MTY: MTOK_04970
MPSC: MPSYJ_22130
MARZ: MARA_54320
MGAD: MGAD_52480
MHEV: MHEL_09990
MSAR: MSAR_27010
MANY: MANY_26880
MAUB: MAUB_43590
MPOF: MPOR_47010
MPHU: MPHO_25810
MMUC: C1S78_005420
MMAT: MMAGJ_05590
MBOK: MBOE_27320
MFG: K6L26_09070
MSEI: MSEDJ_54960
MFLV: NCTC10271_01108
MCEE: MCEL_44150
MMON: EWR22_22255
MGO: AFA91_14490
MHOL: K3U96_06035
MSEN: K3U95_21790
MPAE: K0O64_06045
MRF: MJO55_20980
MDF: K0O62_22395
MCRO: MI149_06755
MGRO: FZ046_26400
MAUS: JN090_22515
MKR: MKOR_40410
MPAK: MIU77_04215
MJD: JDM601_1056
MTER: 4434518_01040
MMIN: MMIN_27080
MHIB: MHIB_06150
MHER: K3U94_05970
MVM: MJO54_06060
SNF: JYK04_07456(auaH_3)
LOB: NEF87_000807
 » show all
Reference
PMID:17630785
  Authors
Yang X, Dubnau E, Smith I, Sampson NS
  Title
Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase.
  Journal
Biochemistry 46:9058-67 (2007)
DOI:10.1021/bi700688x
  Sequence
[mtu:Rv1106c]
Reference
PMID:21257778
  Authors
Yang X, Gao J, Smith I, Dubnau E, Sampson NS
  Title
Cholesterol is not an essential source of nutrition for Mycobacterium tuberculosis during infection.
  Journal
J Bacteriol 193:1473-6 (2011)
DOI:10.1128/JB.01210-10
  Sequence
[mtu:Rv1106c]

  All links  
Ontology (5)   
   KEGG BRITE (2)   
   GO (2)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (170)   
   KEGG GENES (169)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (185)   

Download RDF
DBGET integrated database retrieval system