KEGG   ORTHOLOGY: K16051
Entry
K16051                      KO                                     
Symbol
tesI
Name
3-oxo-5alpha-steroid 4-dehydrogenase [EC:1.3.99.5]
Pathway
map00984  Steroid degradation
map01120  Microbial metabolism in diverse environments
Reaction
R01834  3-oxo-5alpha-steroid:(acceptor) delta4-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00984 Steroid degradation
    K16051  tesI; 3-oxo-5alpha-steroid 4-dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.99  With unknown physiological acceptors
    1.3.99.5  3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)
     K16051  tesI; 3-oxo-5alpha-steroid 4-dehydrogenase
Other DBs
COG: COG1053
GO: 0003865
Genes
PRE: PCA10_43670
PFUW: KF707C_11860
PPUT: L483_14100
PPUN: PP4_27190
PPUU: PputUW4_01680
PKC: PKB_4321
PFZ: AV641_10570
PLQ: AA042_20375
PPSY: AOC04_07870
PSET: THL1_4409
PSIL: PMA3_11575
PKE: DLD99_14665
PUM: HGP31_20980
PPSH: G5J76_13525
PLAL: FXN65_21135
PAZE: KSS91_19195
PTAE: NCTC10697_02064(ifcA_1)
PCAV: D3880_17460
PIZ: LAB08_R40770
PKM: PZ739_11580
PSHS: JJN09_05510
PFOU: OZ911_14115
KAK: Kalk_07950
CBER: B5D82_11210
MSEC: LN244_04835
MRZ: KDW95_00830
ENW: MJO57_21290
EMP: EZMO1_1275(tesI)
SOK: D0B54_05270
SINI: GT972_08465
FCE: JN531_005455
GPB: HDN1F_19870(tesI)
REH: H16_B0641(h16_B0641)
CNC: CNE_2c05860
CUH: BJN34_30935
CTI: RALTA_B0490
CBW: RR42_s2342
COX: E0W60_08150
CUK: KB879_20645
BFN: OI25_4613
PBRY: NDK50_33000
PPAI: E1956_26865 E1956_37100
CABA: SBC2_48770
CTT: CtCNB1_1358
CTES: O987_07765
CRJ: QMY55_07045
DIH: G7047_09730
SMIO: CATMQ487_31560
DOE: DENOEST_3316
TSV: DSM104635_00611
NAR: Saro_3721
NPP: PP1Y_Mpl3259
SWI: Swit_1005 Swit_1860 Swit_3335
SPHD: HY78_08875 HY78_16270 HY78_21490
RDI: CMV14_19635
SPHM: G432_07425
SSAN: NX02_12730
SPKC: KC8_10970
SPHA: D3Y57_03785 D3Y57_15195
SPHB: EP837_01509(tesI)
SPHG: AZE99_00535
NTD: EGO55_03145 EGO55_13615
CAEN: K5X80_05260 K5X80_13780
MUL: MUL_4900
MMI: MMAR_0205
MMAE: MMARE11_01890
MLI: MULP_00179
MPSE: MPSD_53970
MSHO: MSHO_12420
MMC: Mmcs_0302
MKM: Mkms_0312
MJL: Mjls_0293
MKN: MKAN_15315
MYV: G155_02520
MFJ: MFLOJ_21820
MSTO: MSTO_25520
MKU: I2456_01305 I2456_01760
MPAG: C0J29_01190
MNM: MNVM_40340
MGOR: H0P51_01160
MBAI: MB901379_00137
MLJ: MLAC_19640
MSHJ: MSHI_01900
MSPG: F6B93_00910
MOT: LTS72_24685
MKY: IWGMT90018_02350
MSM: MSMEG_2873
MSG: MSMEI_2799
MSB: LJ00_14290
MSN: LI99_14295
MSH: LI98_14300
MGI: Mflv_4564
MSP: Mspyr1_39640
MFT: XA26_04570
MPHL: MPHLCCUG_02608
MVQ: MYVA_1640 MYVA_5433
MTHN: 4412656_00946(ifcA_1)
MHAS: MHAS_02476
MCHT: MCHIJ_12690
MFX: MFAL_17780
MIJ: MINS_21440
MALV: MALV_32080
MAUB: MAUB_04580
MPHU: MPHO_08050
MMUC: C1S78_014220
MBOK: MBOE_16350
MFLV: NCTC10271_02169(ifcA_1)
MMON: EWR22_01615
MDF: K0O62_10315 K0O62_15920
MKR: MKOR_07390
MPAK: MIU77_08035
MAB: MAB_0623
MMV: MYCMA_0323
MABB: MASS_0593
MABL: MMASJCM_0612
MCHE: BB28_02985
MIZ: BAB75_03735
MSTE: MSTE_00582
MSAO: MYCSP_02685
MSAL: DSM43276_00541
MJD: JDM601_2019
MTER: 4434518_01971
MMIN: MMIN_36500
MHIB: MHIB_10920 MHIB_14890
MHER: K3U94_11545
MVM: MJO54_11545
NFA: NFA_4640
NFR: ERS450000_03773(ifcA_3)
NCY: NOCYR_0491
NBR: O3I_002615
NSL: BOX37_17180
NOD: FOH10_02275
NAH: F5544_02605
NAD: NCTC11293_04109(ifcA_2)
NIE: KV110_02995
NTC: KHQ06_36955
NHU: H0264_36175
NYA: LTV02_37155
NGP: LTT66_15370
NSPU: IFM12276_01570
RER: RER_07380
REY: O5Y_03585
REB: XU06_03825
RQI: C1M55_04070
RHOD: AOT96_14465
RTM: G4H71_07430
RGO: KYT97_16405 KYT97_23105
RHOP: D8W71_26930
RHOO: RA302_03945
REQ: REQ_08850
TSM: ASU32_08060
TPUL: TPB0596_44260
TSD: MTP03_16260
CBQ: AL705_03940
AARC: G127AT_04070
AJG: KKR91_06375
ACAO: NF551_01370
FAL: FRAAL3038
AMD: AMED_2521
AMN: RAM_12815
AMM: AMES_2493
AMZ: B737_2494
AOI: AORI_2483
AJA: AJAP_26410
AMQ: AMETH_4839
AMYC: CU254_10455
AMYB: BKN51_05015
AAB: A4R43_16050
AMYY: YIM_14445
AORI: SD37_13480
AACD: LWP59_23765 LWP59_29205
APRT: MUY14_23835
AROO: NQK81_09935
ATHM: L1857_26970
ARHD: VSH64_01775
AMOG: QRX60_26335
ACOR: LCL61_01240
KAL: KALB_5139
KUT: JJ691_07860
KPHY: AOZ06_42835
LED: BBK82_38945
ALO: CRK59602
PMAD: BAY61_10950
SACE: GIY23_13360
CROS: N8J89_29395
STP: Strop_2675
SAQ: Sare_2883
AMS: AMIS_19130
AIH: Aiant_18970
ACTL: L3i22_084550
ASIC: Q0Z83_065660
AOU: ACTOB_004112
ACTE: ACTI_41160
AG: AAB08517(tesI) BAC81693(tesI)
 » show all
Reference
PMID:8655514
  Authors
Florin C, Kohler T, Grandguillot M, Plesiat P
  Title
Comamonas testosteroni 3-ketosteroid-delta 4(5 alpha)-dehydrogenase: gene and protein characterization.
  Journal
J Bacteriol 178:3322-30 (1996)
DOI:10.1128/JB.178.11.3322-3330.1996
  Sequence
[ag:AAB08517]
Reference
PMID:12902225
  Authors
Horinouchi M, Hayashi T, Yamamoto T, Kudo T
  Title
A new bacterial steroid degradation gene cluster in Comamonas testosteroni TA441 which consists of aromatic-compound degradation genes for seco-steroids and 3-ketosteroid dehydrogenase genes.
  Journal
Appl Environ Microbiol 69:4421-30 (2003)
DOI:10.1128/AEM.69.8.4421-4430.2003
  Sequence
[ag:BAC81693]
Reference
PMID:20554032
  Authors
Horinouchi M, Kurita T, Hayashi T, Kudo T
  Title
Steroid degradation genes in Comamonas testosteroni TA441: Isolation of genes encoding a Delta4(5)-isomerase and 3alpha- and 3beta-dehydrogenases and evidence for a 100 kb steroid degradation gene hot spot.
  Journal
J Steroid Biochem Mol Biol 122:253-63 (2010)
DOI:10.1016/j.jsbmb.2010.06.002

  All links  
Ontology (4)   
   KEGG BRITE (2)   
   GO (1)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (2439)   
   KEGG GENES (209)   
   KEGG MGENES (1881)   
   RefGene (346)   
   OC (3)   
Literature (3)   
   PubMed (3)   
All databases (2453)   

Download RDF
DBGET integrated database retrieval system