KEGG   ORTHOLOGY: K16122
Entry
K16122                      KO                                     
Symbol
tycA
Name
tyrocidine synthetase I
Pathway
map01054  Nonribosomal peptide structures
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01054 Nonribosomal peptide structures
    K16122  tycA; tyrocidine synthetase I
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16122  tycA; tyrocidine synthetase I
Polyketide biosynthesis proteins [BR:ko01008]
 Nonribosomal peptide synthetase (NRPS)
  Linear NRPS
   Tyrocidine synthetase
    K16122  tycA; tyrocidine synthetase I
Genes
BBE: BBR47_27870(tycA)
BLR: BRLA_c023760
BFM: BP422_09170
BAGR: BA6348_15120(tycA)
BRW: GOP56_04700
BPAB: PSE45_14525
BREH: HP435_15060
PLV: ERIC2_c19930
AG: AAC45928(tycA)
Reference
PMID:9352938
  Authors
Mootz HD, Marahiel MA
  Title
The tyrocidine biosynthesis operon of Bacillus brevis: complete nucleotide sequence and biochemical characterization of functional internal adenylation domains.
  Journal
J Bacteriol 179:6843-50 (1997)
DOI:10.1128/jb.179.21.6843-6850.1997
  Sequence
Reference
  Authors
Luo L, Kohli RM, Onishi M, Linne U, Marahiel MA, Walsh CT
  Title
Timing of epimerization and condensation reactions in nonribosomal peptide assembly lines: kinetic analysis of phenylalanine activating elongation modules of tyrocidine synthetase B.
  Journal
Biochemistry 41:9184-96 (2002)
DOI:10.1021/bi026047+

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