KEGG   ORTHOLOGY: K16181
Entry
K16181                      KO                                     

Name
pylC
Definition
3-methylornithine--L-lysine ligase [EC:6.3.2.-]
Pathway
ko00300  Lysine biosynthesis
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K16181  pylC; 3-methylornithine--L-lysine ligase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.-  
     K16181  pylC; 3-methylornithine--L-lysine ligase
Other DBs
RN: R10011
COG: COG0458
Genes
DSY: DSY4957
DHD: Dhaf_4856
DDH: Desde_0575
DAE: Dtox_0029
DGI: Desgi_3924
TJR: TherJR_0024
DOR: Desor_1624 Desor_3053
DMI: Desmer_1593
ELIM: B2M23_05180
AMIJ: EQM06_09280(pylC)
AMIC: Ami3637_11540(pylC)
ABUT: Ami103574_12090(pylC)
TPZ: Tph_c24760
AAR: Acear_0359
MANA: MAMMFC1_01956
MBA: Mbar_A0837
MBY: MSBRM_0157
MBW: MSBRW_0164
MBAR: MSBR2_2224
MBAK: MSBR3_2275
MAC: MA_0153
MMA: MM_1443
MMAZ: MmTuc01_1501
MMJ: MSMAS_3221
MMAC: MSMAC_3243
MVC: MSVAZ_3359
MEK: MSKOL_3318
MLS: MSLAZ_3209
METM: MSMTP_3121
MEF: MSWH1_3070
MEQ: MSWHS_3281
MSJ: MSSAC_0135
MSZ: MSSIH_0122
MSW: MSSIT_0126
MTHR: MSTHT_1932
MTHE: MSTHC_1351
MHOR: MSHOH_3967
MFZ: AOB57_008960(pylC)
MBU: Mbur_2084(pylC)
MMET: MCMEM_0283
MMH: Mmah_0281
MHAZ: BHR79_02115
MEV: Metev_0936
MZH: Mzhil_1027
MPY: Mpsy_1723
MZI: HWN40_00975(pylC)
MHZ: Metho_0020
TAR: TALC_01090
MAX: MMALV_11270
MER: MMINT_08910
MEAR: Mpt1_c05680(pylC)
MARC: AR505_1323
 » show all
Reference
  Authors
Gaston MA, Jiang R, Krzycki JA
  Title
Functional context, biosynthesis, and genetic encoding of pyrrolysine.
  Journal
Curr Opin Microbiol 14:342-9 (2011)
DOI:10.1016/j.mib.2011.04.001
Reference
  Authors
Gaston MA, Zhang L, Green-Church KB, Krzycki JA
  Title
The complete biosynthesis of the genetically encoded amino acid pyrrolysine from lysine.
  Journal
Nature 471:647-50 (2011)
DOI:10.1038/nature09918
  Sequence
[mac:MA_0153]

  All links  
Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (95)   
   KEGG GENES (53)   
   KEGG MGENES (23)   
   RefGene (17)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (109)   

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KEGG   REACTION: R10011
Entry
R10011                      Reaction                               

Definition
L-Lysine + (2R,3R)-3-Methylornithine + ATP <=> (2R,3R)-3-Methylornithinyl-N6-lysine + Products of ATP breakdown
Equation
Comment
3-methylornithine--L-lysine ligase
Reaction class
RC00096  C00047_C20278
RC00141  C20277_C20278
Enzyme
6.3.2.-
Pathway
rn00300  Lysine biosynthesis
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K16181  3-methylornithine--L-lysine ligase [EC:6.3.2.-]

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG RCLASS (2)   
Gene (54)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (53)   
All databases (68)   

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