KEGG ORTHOLOGY: K16244

ORTHOLOGY: K16244

Entry

K16244                      KO

Symbol

dmpM, poxC, tomA2

Name

phenol/toluene 2-monooxygenase (NADH) P2/A2 [EC:1.14.13.244 1.14.13.243]

Pathway

map00361

Chlorocyclohexane and chlorobenzene degradation

map00362

Benzoate degradation

map00623

Toluene degradation

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00548

Benzene degradation, benzene => catechol

Reaction

R03560

toluene,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R03608

o-cresol,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R10042

benzene,NADH:oxygen oxidoreductase

R10043

phenol,NADH:oxygen oxidoreductase (2-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16244  dmpM, poxC, tomA2; phenol/toluene 2-monooxygenase (NADH) P2/A2
   00361 Chlorocyclohexane and chlorobenzene degradation
    K16244  dmpM, poxC, tomA2; phenol/toluene 2-monooxygenase (NADH) P2/A2
   00623 Toluene degradation
    K16244  dmpM, poxC, tomA2; phenol/toluene 2-monooxygenase (NADH) P2/A2
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.243  toluene 2-monooxygenase
     K16244  dmpM, poxC, tomA2; phenol/toluene 2-monooxygenase (NADH) P2/A2
    1.14.13.244  phenol 2-monooxygenase (NADH)
     K16244  dmpM, poxC, tomA2; phenol/toluene 2-monooxygenase (NADH) P2/A2

Genes

PSD:

DSC_04430

RTH:	LRK53_10145

RBD:

ALSL_0899

PRE:	PCA10_06980(dmpM)

PFUW:

KF707C_6710(dmpM)

PCQ:	PcP3B5_25320(dmpM)

PPG:	PputGB1_3309

PPJ:	RK21_04246

PVR:	PverR02_14665

PKC:

PKB_1743

PALK:

PSAKL28_05890

PALL:

UYA_20195

PUM:	HGP31_14975

PLAL:

FXN65_03420

PPHN:

HU825_05010

PIZ:	LAB08_R22500

PKM:	PZ739_17305

PKK:	QQ992_10220

PTRL:

OU419_14790

PLAU:

I0D68_00690

AVN:	Avin_08840(dmpM) Avin_30740(lapM)

AVL:	AvCA_08840(dmpM) AvCA_30740(lapM)

AVD:	AvCA6_08840(dmpM) AvCA6_30740(lapM)

HPEG:

HAES:

PPHA:

MAD:

MSR:	AU15_09290 AU15_20705

MLQ:	ASQ50_09255

MSQ:	BKP64_13890

MARJ:

MARI_05350(dmpM)

MALL:

PBN92_01630

MSHE:

MAALD49_03350(mphM) MAALD49_03780(mphM)

MANP:

EHN06_02405

PSPG:

AK823_07315

PSYG:

AK825_07410

ABK:	LX00_05880

ABAU:

IX87_04545

ACC:	BDGL_000473(mphM)

ALC:	OTEC02_12950

ASEI:

I8T81_12965

ACD:	AOLE_13305

AJO:	RZ95_18655

ACW:	A0J50_11605

ALA:	BFG52_11005

ADV:	DJ533_01830 DJ533_11000

AWU:	BEN71_12690

AGU:	AS4_16440(dsoC)

ABER:

BSR55_16095

ACHI:

CDG60_14305

ATG:	J4G44_06370

ACIE:

ACIG:

MCAH:

AFUS:

CZA:	CYCME_2110

THIS:

TBN:

MARS:

MGEO:

MSEC:

MRZ:	KDW95_03640

NCU:	F0U83_03010

NJP:	NEJAP_0664(dmpM)

NIK:	F5I99_10145

AJP:	AMJAP_3009(dmpM)

SINI:

GT972_13685

NZO:	SAMEA4504057_0439(dmpM)

NCI:	NCTC10296_00922(dmpM)

NWD:	H3L96_04800

NDU:	LVJ88_00555

VFF:	VITFI_CDS1383

PTES:

JQU52_04825

USU:	LVJ78_03625

AQL:	BXU06_12760 BXU06_16825

RPI:

Rpic_4629

RPF:	Rpic12D_3553

RPJ:	N234_08115

REH:	H16_B0541(poxC)

CNC:	CNE_2c04870(poxC)

REU:	Reut_A1701 Reut_B5682

RME:	Rmet_1329(tomA2) Rmet_1785(phyB)

CBW:	RR42_s2491

CCUP:

BKK81_27055

CUP:	BKK80_29265

CUU:	BKK79_35215

COX:	E0W60_07740

CCAX:

KZ686_09950

CUK:	KB879_20155

CNAN:

A2G96_22735

BVI:	Bcep1808_7595

BUR:	Bcep18194_B2969

BCEN:

DM39_4842(dmpM)

BCT:

GEM_5411

BCED:

DM42_5001(dmpM)

BCON:

NL30_24640

BDF:	WI26_15945

BTEI:

BPSL:

BSTL:

BANN:

BAEN:

BYI:	BYI23_C000550(mmoB_dmpM)

BUE:	BRPE67_CCDS12520(mmoB_dmpM)

BUZ:	AYM40_16210

PARB:

PTER:

PPAI:

PHUN:

PPK:	U875_01940

PRB:	X636_07530

CABK:

NK8_49950

LIMN:

HKT17_03895

BOJ:	CBF45_04555

APES:

FOC84_00370

CDN:	BN940_04356

AFA:	UZ73_17840

AFQ:

AFA_08525

AAQU:

D3M96_09745

AAMM:

FE795_07740

PIG:	EGT29_26550

KGY:	EHF36_04940

RLH:	MIZ03_0641 MIZ03_1013

AJS:

ACID:

ACIP:

ACIN:

ACIS:

AMON:

VEI:

VBO:	CKY39_28545

VAV:	IG196_08090

CTT:	CtCNB1_3160

COF:	FOZ74_08260

ADN:	Alide_0325

ADK:	Alide2_0272

OTD:	J1M35_00095

HYL:	LPB072_18135

HPSE:

HPF_01920(dmpM)

HYN:	F9K07_02705

HTN:	KI616_02010

DIH:	G7047_01720

DRG:	H9K76_11595

SIMP:

C6571_13575

MELA:

C6568_07900

MJE:	LVC68_00960

STHM:

IS481_10485

SAQA:

OMP39_09065

MPT:	Mpe_A2283(dmpM) Mpe_A3307(dmpM)

METP:

C1M51_06290 C1M51_15450

SNN:	EWH46_19260

SMIO:

CATMQ487_04200

IDC:	LRM40_19520

LCH:

Lcho_3361

MASW:

AM586_18615

MLIR:

LPB04_16110

TMJ:	P0M04_30700

RBU:	PG1C_06900

DAR:

Daro_3795

DEY:	HYN24_14150 HYN24_14265

DDEN:

KI615_16935

DECH:

GBK02_02785

QAU:	KI612_13875

FLE:	KI610_15400 KI610_15515

AZO:	azo1847(lapM) azo2442(poxC)

AOA:	dqs_1997 dqs_2586

AZD:	CDA09_10260 CDA09_10415

AZR:	CJ010_12200 CJ010_15260

TMZ:	Tmz1t_3114

THU:	AC731_001770

THAU:

C4PIVTH_2794(dmpM)

THK:	CCZ27_04540 CCZ27_10670 CCZ27_10795

THAG:

CKCBHOJB_01540(dmpM)

AZQ:	G3580_00475 G3580_01300 G3580_08215

MTUN:

MTUNDRAET4_3882(dmpM)

MAAD:

AZF01_11205

MLUT:

JET14_11650

BVY:	NCTC9239_03025(dmpM)

SMY:	BJP26_18675

SHAN:

PPZ50_08280

SJP:	SJA_C1-12000(tomA2)

SINB:

SIDU_08265

SYB:	TZ53_09075

SUFL:

FIL70_18940

SBAR:

H5V43_20590

ACIB:

ACBT_0278(dmpM)

AFC:	AFAEC_1856(dmpM)

AAQI:

AAQM_0971(dmpM)

ACLO:

ACLO_a0153(dmpM)

ADZ:	ADFLV_2567(dmpM)

ARC:

ABLL_2458

AROS:

NJU99_01600

ALK:	ALEK_0372(dmpM)

AANA:

AANAER_1247(dmpM)

BACI:

B1NLA3E_08460

ASOC:

CB4_02442(dmpM)

AUD:	PO771_08945

BTS:

Btus_0960

KYR:	CVV65_10615 CVV65_11335

SAY:

TPY_0629

SAP:	Sulac_3010

MSA:	Mycsm_01965

MLL:	B1R94_25110

MMAG:

MMAD_31790

MCRO:

MI149_22720

MAUS:

JN090_29450

GOQ:	ACH46_03530

GOC:	CXX93_06735

GAM:	GII34_22055

GSI:	P5P27_15505

TOY:	FO059_13970

JTE:	ASJ30_00065

JLI:	EXU32_15400

JME:	EEW87_015370

JAY:	H7A72_00065

JCR:	O9K63_12550

RAIN:

Rai3103_07190

NMES:

H9L09_04340

TCU:

Tcur_0525

AACD:

LWP59_26120 LWP59_38110

ARHD:

VSH64_31605

PDX:

Psed_0769

PSUU:

Psuf_068240

AG:	BAA23332(dsoC)

» show all

Reference

PMID:2254258

Authors

Nordlund I, Powlowski J, Shingler V

Title

Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600.

Journal

J Bacteriol 172:6826-33 (1990)
DOI:10.1128/jb.172.12.6826-6833.1990

Sequence

[ppj:RK21_04246]

Reference

PMID:11751810

Authors

Canada KA, Iwashita S, Shim H, Wood TK

Title

Directed evolution of toluene ortho-monooxygenase for enhanced 1-naphthol synthesis and chlorinated ethene degradation.

Journal

J Bacteriol 184:344-9 (2002)
DOI:10.1128/jb.184.2.344-349.2002

Sequence

[bvi:Bcep1808_7595]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical reaction (8)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
   KEGG RCLASS (2)   
Gene (557)   
   KEGG GENES (248)   
   KEGG MGENES (257)   
   RefGene (51)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (582)   

Download RDF

ORTHOLOGY: K16249

Entry

K16249                      KO

Symbol

dmpK, poxA, tomA0

Name

phenol/toluene 2-monooxygenase (NADH) P0/A0

Pathway

map00361

Chlorocyclohexane and chlorobenzene degradation

map00362

Benzoate degradation

map00623

Toluene degradation

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00548

Benzene degradation, benzene => catechol

Reaction

R03560

toluene,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R03608

o-cresol,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R10042

benzene,NADH:oxygen oxidoreductase

R10043

phenol,NADH:oxygen oxidoreductase (2-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16249  dmpK, poxA, tomA0; phenol/toluene 2-monooxygenase (NADH) P0/A0
   00361 Chlorocyclohexane and chlorobenzene degradation
    K16249  dmpK, poxA, tomA0; phenol/toluene 2-monooxygenase (NADH) P0/A0
   00623 Toluene degradation
    K16249  dmpK, poxA, tomA0; phenol/toluene 2-monooxygenase (NADH) P0/A0

Genes

PSD:

DSC_04440

RTH:	LRK53_10135

RBD:

ALSL_0901

PRE:	PCA10_06960(dmpK)

PFUW:

KF707C_6690(dmpK)

PCQ:	PcP3B5_25300

PPG:	PputGB1_3311

PPJ:	RK21_04248

PVR:	PverR02_14655

PKC:

PKB_1741

PALK:

PSAKL28_05870

PALL:

UYA_20205

PUM:	HGP31_14965

PLAL:

FXN65_03410

PPHN:

HU825_05020

PIZ:	LAB08_R22480

PKM:	PZ739_17315

PKK:	QQ992_10210

PTRL:

OU419_14800

PLAU:

I0D68_00700

AVN:	Avin_08860(dmpK) Avin_30760(lapK)

AVL:	AvCA_08860(dmpK) AvCA_30760(lapK)

AVD:	AvCA6_08860(dmpK) AvCA6_30760(lapK)

HPEG:

HAES:

PPHA:

MAD:

MSR:	AU15_09280 AU15_20715

MLQ:	ASQ50_09265

MSQ:	BKP64_13900

MARJ:

MARI_05330

MALL:

PBN92_01620

MSHE:

MAALD49_03330 MAALD49_03760(mphK)

MANP:

EHN06_02395

PSPG:

AK823_07325

PSYG:

AK825_07420

ABK:	LX00_05890

ABAU:

IX87_04535

ACC:	BDGL_000476(mphK)

ALC:	OTEC02_12940

ASEI:

I8T81_12955

ACD:	AOLE_13295

AJO:	RZ95_18665

ACW:	A0J50_11595

ALA:	BFG52_10995

ADV:	DJ533_01840 DJ533_10990

AWU:	BEN71_12680

AGU:	AS4_16460(dsoA)

ABER:

BSR55_16085

ACHI:

CDG60_14295

ATG:	J4G44_06360

APOT:

ACIE:

ACIG:

MCAH:

AFUS:

CZA:	CYCME_2112

BLEP:

THIS:

TBN:

MARS:

MGEO:

MSEC:

MRZ:	KDW95_03630

NCU:	F0U83_03000

NJP:	NEJAP_0662(dmpK)

NIK:	F5I99_10155

AJP:	AMJAP_3011(dmpK)

SINI:

GT972_13675

NZO:	SAMEA4504057_0437

NCI:	NCTC10296_00924

NWD:	H3L96_04810

NDU:	LVJ88_00545

VFF:	VITFI_CDS1381

PTES:

JQU52_04815

USU:	LVJ78_03615

AQL:	BXU06_12750 BXU06_16815

RPI:

Rpic_4631

RPF:	Rpic12D_3555

RPJ:	N234_08105

REH:	H16_B0539(poxA)

CNC:	CNE_2c04850(poxA)

REU:	Reut_A1699 Reut_B5680

RME:	Rmet_1331(tomA0) Rmet_1787

CBW:	RR42_s2493

CCUP:

BKK81_27045

CUP:	BKK80_29275

CUU:	BKK79_35225

COX:	E0W60_07730

CCAX:

KZ686_09940

CUK:	KB879_20145

CNAN:

A2G96_22725

BVI:	Bcep1808_7593

BUR:	Bcep18194_B2971

BCEN:

BCT:

BCED:

BCON:

BDF:	WI26_15935

BTEI:

BPSL:

BSTL:

BANN:

BAEN:

BYI:	BYI23_C000570

BUE:	BRPE67_CCDS12500

PARB:

PTER:

PPAI:

PHUN:

PPK:	U875_01950

PRB:	X636_07520

CABK:

NK8_49930

LIMN:

HKT17_03905

BOJ:	CBF45_04565

APES:

FOC84_00380

AFA:	UZ73_17830

AFQ:

AFA_08515

AAQU:

D3M96_09735

AAMM:

FE795_07730

PIG:	EGT29_26560

KGY:	EHF36_04950

RLH:	MIZ03_0639 MIZ03_1011

AJS:

ACID:

ACIP:

ACIN:

ACIS:

AMON:

VEI:

VBO:	CKY39_28555

VAV:	IG196_08080

CTT:	CtCNB1_3162

COF:	FOZ74_08250

ADN:	Alide_0323

ADK:	Alide2_0270

OTD:	J1M35_00105

HYL:	LPB072_18125

HPSE:

HPF_01930

HYN:	F9K07_02695

HTN:	KI616_02020

DIH:	G7047_01730

DRG:	H9K76_11585

SIMP:

C6571_13565

MELA:

C6568_07910

MJE:	LVC68_00950

STHM:

IS481_10475

SAQA:

OMP39_09055

MPT:	Mpe_A2285(dmpK) Mpe_A3309(dmpK)

METP:

C1M51_06300 C1M51_15460

SNN:	EWH46_19270

SMIO:

CATMQ487_04220

IDC:	LRM40_19510

LCH:

Lcho_3363

MLIR:

LPB04_16120

TMJ:	P0M04_30710

DAR:

Daro_3797

DEY:	HYN24_14275

DDEN:

KI615_16945

DECH:

GBK02_02775

QAU:	KI612_13885

FLE:	KI610_15525

AZO:	azo1845(lapK) azo2444(poxA)

AOA:	dqs_1995 dqs_2588

AZD:	CDA09_10250 CDA09_10405

AZR:	CJ010_12190 CJ010_15270

TMZ:	Tmz1t_3116

THU:	AC731_001760

THAU:

C4PIVTH_2792

THK:	CCZ27_04530 CCZ27_10805

THAG:

CKCBHOJB_01538

AZQ:	G3580_00465 G3580_08205

MTUN:

MTUNDRAET4_3880

MLUT:

JET14_11640

BVY:	NCTC9239_03023

SJP:	SJA_C1-11980(tomA0)

SINB:

SIDU_08275

SYB:	TZ53_09065

SUFL:

FIL70_18950

SBAR:

H5V43_20600

HTL:

HPTL_0057

ACIB:

ACBT_0280(dmpK)

AFC:	AFAEC_1858(dmpK)

AAQI:

AAQM_0969(dmpK)

ACLO:

ACLO_a0155(dmpK)

ADZ:	ADFLV_2569(dmpK)

ARC:

ABLL_2460

AROS:

NJU99_01590

ALK:	ALEK_0370(dmpK)

AANA:

AANAER_1245(dmpK)

AG:	BAA23330(dsoA)

» show all

Reference

PMID:2254258

Authors

Nordlund I, Powlowski J, Shingler V

Title

Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600.

Journal

J Bacteriol 172:6826-33 (1990)
DOI:10.1128/jb.172.12.6826-6833.1990

Sequence

[ppj:RK21_04248]

Reference

PMID:11751810

Authors

Canada KA, Iwashita S, Shim H, Wood TK

Title

Directed evolution of toluene ortho-monooxygenase for enhanced 1-naphthol synthesis and chlorinated ethene degradation.

Journal

J Bacteriol 184:344-9 (2002)
DOI:10.1128/jb.184.2.344-349.2002

Sequence

[bvi:Bcep1808_7593]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical reaction (6)   
   KEGG REACTION (4)   
   KEGG RCLASS (2)   
Gene (514)   
   KEGG GENES (209)   
   KEGG MGENES (272)   
   RefGene (31)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (536)   

Download RDF

ORTHOLOGY: K16243

Entry

K16243                      KO

Symbol

dmpL, poxB, tomA1

Name

phenol/toluene 2-monooxygenase (NADH) P1/A1 [EC:1.14.13.244 1.14.13.243]

Pathway

map00361

Chlorocyclohexane and chlorobenzene degradation

map00362

Benzoate degradation

map00623

Toluene degradation

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00548

Benzene degradation, benzene => catechol

Reaction

R03560

toluene,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R03608

o-cresol,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R10042

benzene,NADH:oxygen oxidoreductase

R10043

phenol,NADH:oxygen oxidoreductase (2-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16243  dmpL, poxB, tomA1; phenol/toluene 2-monooxygenase (NADH) P1/A1
   00361 Chlorocyclohexane and chlorobenzene degradation
    K16243  dmpL, poxB, tomA1; phenol/toluene 2-monooxygenase (NADH) P1/A1
   00623 Toluene degradation
    K16243  dmpL, poxB, tomA1; phenol/toluene 2-monooxygenase (NADH) P1/A1
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.243  toluene 2-monooxygenase
     K16243  dmpL, poxB, tomA1; phenol/toluene 2-monooxygenase (NADH) P1/A1
    1.14.13.244  phenol 2-monooxygenase (NADH)
     K16243  dmpL, poxB, tomA1; phenol/toluene 2-monooxygenase (NADH) P1/A1

Genes

PSD:

DSC_04435

RTH:	LRK53_10140

RBD:

ALSL_0900

PRE:	PCA10_06970(dmpL)

PFUW:

KF707C_6700(dmpL)

PCQ:	PcP3B5_25310(mphL)

PPG:	PputGB1_3310

PPJ:	RK21_04247

PVR:	PverR02_14660

PKC:	PKB_1742(dmpL)

PALK:

PSAKL28_05880

PALL:

UYA_20200

PUM:	HGP31_14970

PLAL:

FXN65_03415

PPHN:

HU825_05015

PIZ:	LAB08_R22490

PKM:	PZ739_17310

PKK:	QQ992_10215

PTRL:

OU419_14795

PLAU:

I0D68_00695

AVN:	Avin_08850(dpmL) Avin_30750(lapL)

AVL:	AvCA_08850(dpmL) AvCA_30750(lapL)

AVD:	AvCA6_08850(dpmL) AvCA6_30750(lapL)

HPEG:

HAES:

PPHA:

MAD:

MSR:	AU15_09285 AU15_20710

MLQ:	ASQ50_09260

MSQ:	BKP64_13895

MARJ:

MARI_05340(mphL)

MALL:

PBN92_01625

MSHE:

MAALD49_03340(mphL) MAALD49_03770(mphL)

MANP:

EHN06_02400

PSPG:

AK823_07320

PSYG:

AK825_07415

ABK:	LX00_05885

ABAU:

IX87_04540

ACC:	BDGL_000474(mphL)

ALC:	OTEC02_12945

ASEI:

I8T81_12960

ACD:	AOLE_13300

AJO:	RZ95_18660

ACW:	A0J50_11600

ALA:	BFG52_11000

ADV:	DJ533_01835 DJ533_10995

AWU:	BEN71_12685

AGU:	AS4_16450(dsoB)

ABER:

BSR55_16090

ACHI:

CDG60_14300

ATG:	J4G44_06365

ACIE:

ACIG:

MCAH:

AFUS:

CZA:	CYCME_2111

THIS:

TBN:

MARS:

MGEO:

MSEC:

MRZ:	KDW95_03635

NCU:	F0U83_03005

NJP:	NEJAP_0663(dmpL)

NIK:	F5I99_10150

AJP:	AMJAP_3010(dmpL)

SINI:

GT972_13680

NZO:	SAMEA4504057_0438(mphL)

NCI:	NCTC10296_00923(mphL)

NWD:	H3L96_04805

NDU:	LVJ88_00550

VFF:	VITFI_CDS1382

PTES:

JQU52_04820

USU:	LVJ78_03620

AQL:	BXU06_12755 BXU06_16820

RPI:

Rpic_4630

RPF:	Rpic12D_3554

RPJ:	N234_08110

REH:	H16_B0540(poxB)

CNC:	CNE_2c04860(poxB)

REU:	Reut_A1700 Reut_B5681

RME:	Rmet_1330(tomA1) Rmet_1786(phyA)

CBW:	RR42_s2492

CCUP:

BKK81_27050

CUP:	BKK80_29270

CUU:	BKK79_35220

COX:	E0W60_07735

CCAX:

KZ686_09945

CUK:	KB879_20150

CNAN:

A2G96_22730

BVI:	Bcep1808_7594

BUR:	Bcep18194_B2970

BCEN:

DM39_4843(mphL)

BCT:

GEM_5412

BCED:

DM42_5002(phL)

BCON:

NL30_24645

BDF:	WI26_15940

BTEI:

BPSL:

BSTL:

BANN:

BAEN:

BYI:	BYI23_C000560

BUE:	BRPE67_CCDS12510

BUZ:	AYM40_16215

PARB:

PTER:

PPAI:

PHUN:

PPK:	U875_01945

PRB:	X636_07525

CABK:

NK8_49940

LIMN:

HKT17_03900

BOJ:	CBF45_04560

APES:

FOC84_00375

CDN:	BN940_04361

AFA:	UZ73_17835

AFQ:

AFA_08520

AAQU:

D3M96_09740

AAMM:

FE795_07735

PIG:	EGT29_26555

KGY:	EHF36_04945

RLH:	MIZ03_0640 MIZ03_1012

AJS:

ACIP:

ACIN:

ACIS:

AMON:

VEI:

VBO:	CKY39_28550

VAV:	IG196_08085

CTT:	CtCNB1_3161

COF:	FOZ74_08255

ADN:	Alide_0324

ADK:	Alide2_0271

OTD:	J1M35_00100

HYL:	LPB072_18130

HPSE:

HPF_01925(mphL)

HYN:	F9K07_02700

HTN:	KI616_02015

DIH:	G7047_01725

DRG:	H9K76_11590

SIMP:

C6571_13570

MELA:

C6568_07905

MJE:	LVC68_00955

STHM:

IS481_10480

SAQA:

OMP39_09060

MPT:	Mpe_A2284(dmpL) Mpe_A3308(dmpL)

METP:

C1M51_06265 C1M51_06295 C1M51_15455

SNN:	EWH46_19265

SMIO:

CATMQ487_04210(mphL)

IDC:	LRM40_19515

LCH:

Lcho_3362

MASW:

AM586_18610

MLIR:

LPB04_16115

TMJ:	P0M04_30705

RBU:	PG1C_06905

DAR:

Daro_3796

DEY:	HYN24_14155 HYN24_14270

DDEN:

KI615_16940

DECH:

GBK02_02780

QAU:	KI612_13880

FLE:	KI610_15405 KI610_15520

AZO:	azo1846(lapL) azo2443(poxB)

AOA:	dqs_1996 dqs_2587

AZD:	CDA09_10255 CDA09_10410

AZR:	CJ010_12195 CJ010_15265

TMZ:	Tmz1t_3115

THU:	AC731_001765

THAU:

C4PIVTH_2793(dmpL)

THK:	CCZ27_04535 CCZ27_10665 CCZ27_10800

THAG:

CKCBHOJB_01539(mphL)

AZQ:	G3580_00470 G3580_01295 G3580_08210

MTUN:

MTUNDRAET4_3881(dmpL)

MAAD:

AZF01_11200

MLUT:

JET14_11645

BVY:	NCTC9239_03024(mphL)

SMY:	BJP26_18670

SHAN:

PPZ50_08275

SJP:	SJA_C1-11990(tomA1)

SINB:

SIDU_08270

SYB:	TZ53_09070

SUFL:

FIL70_18945

SBAR:

H5V43_20595

ACIB:

ACBT_0279(dmpL)

AFC:	AFAEC_1857(dmpL)

AAQI:

AAQM_0970(dmpL)

ACLO:

ACLO_a0154(dmpL)

ADZ:	ADFLV_2568(dmpL)

ARC:

ABLL_2459

AROS:

NJU99_01595

ALK:	ALEK_0371(dmpL)

AANA:

AANAER_1246(dmpL)

BACI:

B1NLA3E_08455

ASOC:

CB4_02441(mphL)

AUD:	PO771_08940

BTS:

Btus_0959

KYR:	CVV65_10620 CVV65_11340

SAY:

TPY_0628

SAP:	Sulac_3011

MSA:	Mycsm_01964

MLL:	B1R94_25115

GOQ:	ACH46_03525

GOC:	CXX93_06730

GAM:	GII34_22060

GSI:	P5P27_15510

TOY:	FO059_13965

JTE:	ASJ30_00060

JLI:	EXU32_15405

JME:	EEW87_015365

JAY:	H7A72_00060

JCR:	O9K63_12545

PHW:	G7075_13225

AUS:	IPK37_11610

RAIN:

Rai3103_07195

TCU:

Tcur_0524

AACD:

LWP59_26125 LWP59_38115

ARHD:

VSH64_31610

PDX:

Psed_0770

PSUU:

Psuf_068230(mphL)

AG:	BAA23331(dsoB)

» show all

Reference

PMID:22885747

Authors

Dalvi S, Azetsu S, Patrauchan MA, Aktas DF, Fathepure BZ

Title

Proteogenomic elucidation of the initial steps in the benzene degradation pathway of a novel halophile, Arhodomonas sp. strain Rozel, isolated from a hypersaline environment.

Journal

Appl Environ Microbiol 78:7309-16 (2012)
DOI:10.1128/AEM.01327-12

Reference

PMID:2254258

Authors

Nordlund I, Powlowski J, Shingler V

Title

Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600.

Journal

J Bacteriol 172:6826-33 (1990)
DOI:10.1128/jb.172.12.6826-6833.1990

Sequence

[ppj:RK21_04247]

Reference

PMID:11751810

Authors

Canada KA, Iwashita S, Shim H, Wood TK

Title

Directed evolution of toluene ortho-monooxygenase for enhanced 1-naphthol synthesis and chlorinated ethene degradation.

Journal

J Bacteriol 184:344-9 (2002)
DOI:10.1128/jb.184.2.344-349.2002

Sequence

[bvi:Bcep1808_7594]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical reaction (8)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
   KEGG RCLASS (2)   
Gene (693)   
   KEGG GENES (246)   
   KEGG MGENES (374)   
   RefGene (72)   
   OC (1)   
Literature (3)   
   PubMed (3)   
All databases (719)   

Download RDF

ORTHOLOGY: K16242

Entry

K16242                      KO

Symbol

dmpN, poxD, tomA3

Name

phenol/toluene 2-monooxygenase (NADH) P3/A3 [EC:1.14.13.244 1.14.13.243]

Pathway

map00361

Chlorocyclohexane and chlorobenzene degradation

map00362

Benzoate degradation

map00623

Toluene degradation

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00548

Benzene degradation, benzene => catechol

Reaction

R03560

toluene,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R03608

o-cresol,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R10042

benzene,NADH:oxygen oxidoreductase

R10043

phenol,NADH:oxygen oxidoreductase (2-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16242  dmpN, poxD, tomA3; phenol/toluene 2-monooxygenase (NADH) P3/A3
   00361 Chlorocyclohexane and chlorobenzene degradation
    K16242  dmpN, poxD, tomA3; phenol/toluene 2-monooxygenase (NADH) P3/A3
   00623 Toluene degradation
    K16242  dmpN, poxD, tomA3; phenol/toluene 2-monooxygenase (NADH) P3/A3
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.243  toluene 2-monooxygenase
     K16242  dmpN, poxD, tomA3; phenol/toluene 2-monooxygenase (NADH) P3/A3
    1.14.13.244  phenol 2-monooxygenase (NADH)
     K16242  dmpN, poxD, tomA3; phenol/toluene 2-monooxygenase (NADH) P3/A3

Genes

PSD:

DSC_04425

RTH:	LRK53_10150

RBD:

ALSL_0898

PRE:	PCA10_06990(dmpN)

PFUW:

KF707C_6720(dmpN)

PCQ:	PcP3B5_25330(tmoA)

PPG:	PputGB1_3308

PPJ:	RK21_04244 RK21_04245

PVR:	PverR02_14670

PKC:	PKB_1744(dmpN)

PALK:

PSAKL28_05900

PALL:

UYA_20190

PUM:	HGP31_14980

PLAL:

FXN65_03425

PPHN:

HU825_05005

PIZ:	LAB08_R22510

PKM:	PZ739_17300

PKK:	QQ992_10225

PTRL:

OU419_14785

AVN:	Avin_08830(dmpN) Avin_30730(lapN)

AVL:	AvCA_08830(dmpN) AvCA_30730(lapN)

AVD:	AvCA6_08830(dmpN) AvCA6_30730(lapN)

HPEG:

HAES:

PPHA:

MAD:

MLQ:	ASQ50_09250

MSQ:	BKP64_13885

MARJ:

MARI_05360(tmoA)

MALL:

PBN92_01635

MSHE:

MAALD49_03360(mphN) MAALD49_03790(mphN)

MANP:

EHN06_02410

PSPG:

AK823_07310

PSYG:

AK825_07405

ABK:	LX00_05875

ABAU:

IX87_04550

ACC:	BDGL_000472(mphN)

ALC:	OTEC02_12955

ASEI:

I8T81_12970

ACD:	AOLE_13310

AJO:	RZ95_18650

ACW:	A0J50_11610

ALA:	BFG52_11010

ADV:	DJ533_01825 DJ533_11005

AWU:	BEN71_12695

AGU:	AS4_16430(dsoD)

ABER:

BSR55_16100

ACHI:

CDG60_14310

ATG:	J4G44_06375

ACIE:

ACIG:

MCAH:

AFUS:

CZA:	CYCME_2109

BLEP:

THIS:

TBN:

MARS:

MGEO:

MSEC:

MRZ:	KDW95_03645

NCU:	F0U83_03015

NJP:	NEJAP_0665(dmpN)

NIK:	F5I99_10140

AJP:	AMJAP_3008(dmpN)

SINI:

GT972_13690

NZO:	SAMEA4504057_0440(tmoA)

NCI:	NCTC10296_00921(tmoA)

NWD:	H3L96_04795

NDU:	LVJ88_00560

VFF:	VITFI_CDS1384

PTES:

JQU52_04830

USU:	LVJ78_03630

AQL:	BXU06_12765 BXU06_16830

RPI:

Rpic_4628

RPF:	Rpic12D_3552

RPJ:	N234_08120

REH:	H16_B0542(poxD)

CNC:	CNE_2c04880(poxD)

REU:	Reut_A1702 Reut_B5683

RME:	Rmet_1328(tomA3) Rmet_1784(phyC)

CBW:	RR42_s2490

CCUP:

BKK81_27060

CUP:	BKK80_29260

CUU:	BKK79_35210

COX:	E0W60_07745

CCAX:

KZ686_09955

CUK:	KB879_20160

CNAN:

A2G96_22740

BVI:	Bcep1808_7596

BUR:	Bcep18194_B2968

BCEN:

DM39_4841(phN)

BCT:

GEM_5410

BCED:

DM42_5000(phN)

BCON:

NL30_24635

BDF:	WI26_15950

BTEI:

BPSL:

BSTL:

BANN:

BAEN:

BYI:	BYI23_C000540

BUE:	BRPE67_CCDS12530

BUZ:	AYM40_16205

PARB:

PTER:

PPAI:

PHUN:

PPK:	U875_01935

PRB:	X636_07535

CABK:

NK8_49960

LIMN:

HKT17_03890

BOJ:	CBF45_04550

APES:

FOC84_00365

CDN:	BN940_04351

AFA:	UZ73_17845

AFQ:

AFA_08530

AAQU:

D3M96_09750

AAMM:

FE795_07745

PIG:	EGT29_26545

KGY:	EHF36_04935

RLH:	MIZ03_0642 MIZ03_1014

AJS:

ACIP:

ACIN:

ACIS:

AMON:

VEI:

VBO:	CKY39_28540

VAV:	IG196_08095

CTT:	CtCNB1_3159

COF:	FOZ74_08265

ADN:	Alide_0326

ADK:	Alide2_0273

OTD:	J1M35_00090

HYL:	LPB072_18140

HPSE:

HPF_01915(tmoA2)

HYN:	F9K07_02710

HTN:	KI616_02005

DIH:	G7047_01715

DRG:	H9K76_11600

SIMP:

C6571_13580

MELA:

C6568_07895

MJE:	LVC68_00965

STHM:

IS481_10490

SAQA:

OMP39_09070

MPT:	Mpe_A2282(dmpN) Mpe_A3306(dmpN)

METP:

C1M51_06260 C1M51_06285 C1M51_15445

SNN:	EWH46_19255

SMIO:

CATMQ487_04190(mphN)

IDC:	LRM40_19525

LCH:

Lcho_3360

MASW:

AM586_18620

MLIR:

LPB04_16105

TMJ:	P0M04_30695

RBU:	PG1C_06895

DAR:

Daro_3794

DEY:	HYN24_14145 HYN24_14260

DDEN:

KI615_16930

DECH:

GBK02_02790

QAU:	KI612_13870

FLE:	KI610_15395 KI610_15510

AZO:	azo1848(lapN) azo2441(poxD)

AOA:	dqs_1998 dqs_2585

AZD:	CDA09_10265 CDA09_10420

AZR:	CJ010_12205 CJ010_15255

TMZ:	Tmz1t_3113

THU:	AC731_001775

THAU:

C4PIVTH_2795(dmpN)

THK:	CCZ27_04545 CCZ27_10675 CCZ27_10790

THAG:

CKCBHOJB_01541(tmoA)

AZQ:	G3580_00480 G3580_01305 G3580_08220

MTUN:

MTUNDRAET4_3883

MAAD:

AZF01_11210

MLUT:

JET14_11655

BVY:	NCTC9239_03026(tmoA)

SMY:	BJP26_18680

SHAN:

PPZ50_08285

SJP:	SJA_C1-12010(tomA3)

SINB:

SIDU_08260

SYB:	TZ53_09080

SUFL:

FIL70_18935

SBAR:

H5V43_20585

ACIB:

ACBT_0277(dmpN)

AFC:	AFAEC_1855(dmpN)

AAQI:

AAQM_0972(dmpN)

ACLO:

ACLO_a0152(dmpN)

ADZ:	ADFLV_2566(dmpN)

ARC:

ABLL_2457

AROS:

NJU99_01605

ALK:	ALEK_0373(dmpN)

AANA:

AANAER_1248(dmpN)

BACI:

B1NLA3E_08465

ASOC:

CB4_02443(tmoA)

AUD:	PO771_08950

BTS:

Btus_0961

KYR:	CVV65_10610 CVV65_11330

SAY:

TPY_0630

SAP:	Sulac_3009

MSA:	Mycsm_01966

MMAG:

MMAD_31810(mphN)

MCRO:

MI149_22730

MAUS:

JN090_29440

RHOJ:

JVH1_41535(isoA)

GOQ:	ACH46_03535

GOC:	CXX93_06740

GAM:	GII34_22050

GSI:	P5P27_15500

TOY:	FO059_13975

JTE:	ASJ30_00070

JLI:	EXU32_15395

JME:	EEW87_015375

JAY:	H7A72_00070

JCR:	O9K63_12555

PHW:	G7075_13215

AUS:	IPK37_11620

RAIN:

Rai3103_07185

TCU:

Tcur_0526

AACD:

LWP59_26115 LWP59_38105

ARHD:

VSH64_31600

PDX:

Psed_0768

PSUU:

Psuf_068250(mphN)

AG:	BAA23333(dsoD)

» show all

Reference

PMID:22885747

Authors

Dalvi S, Azetsu S, Patrauchan MA, Aktas DF, Fathepure BZ

Title

Proteogenomic elucidation of the initial steps in the benzene degradation pathway of a novel halophile, Arhodomonas sp. strain Rozel, isolated from a hypersaline environment.

Journal

Appl Environ Microbiol 78:7309-16 (2012)
DOI:10.1128/AEM.01327-12

Reference

PMID:2254258

Authors

Nordlund I, Powlowski J, Shingler V

Title

Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600.

Journal

J Bacteriol 172:6826-33 (1990)
DOI:10.1128/jb.172.12.6826-6833.1990

Sequence

[ppj:RK21_04245]

Reference

PMID:11751810

Authors

Canada KA, Iwashita S, Shim H, Wood TK

Title

Directed evolution of toluene ortho-monooxygenase for enhanced 1-naphthol synthesis and chlorinated ethene degradation.

Journal

J Bacteriol 184:344-9 (2002)
DOI:10.1128/jb.184.2.344-349.2002

Sequence

[bvi:Bcep1808_7596]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical reaction (8)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
   KEGG RCLASS (2)   
Gene (835)   
   KEGG GENES (247)   
   KEGG MGENES (476)   
   RefGene (110)   
   OC (2)   
Literature (3)   
   PubMed (3)   
All databases (861)   

Download RDF

ORTHOLOGY: K16246

Entry

K16246                      KO

Symbol

dmpP, poxF, tomA5

Name

phenol/toluene 2-monooxygenase (NADH) P5/A5 [EC:1.14.13.244 1.14.13.243]

Pathway

map00361

Chlorocyclohexane and chlorobenzene degradation

map00362

Benzoate degradation

map00623

Toluene degradation

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00548

Benzene degradation, benzene => catechol

Reaction

R03560

toluene,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R03608

o-cresol,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R10042

benzene,NADH:oxygen oxidoreductase

R10043

phenol,NADH:oxygen oxidoreductase (2-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16246  dmpP, poxF, tomA5; phenol/toluene 2-monooxygenase (NADH) P5/A5
   00361 Chlorocyclohexane and chlorobenzene degradation
    K16246  dmpP, poxF, tomA5; phenol/toluene 2-monooxygenase (NADH) P5/A5
   00623 Toluene degradation
    K16246  dmpP, poxF, tomA5; phenol/toluene 2-monooxygenase (NADH) P5/A5
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.243  toluene 2-monooxygenase
     K16246  dmpP, poxF, tomA5; phenol/toluene 2-monooxygenase (NADH) P5/A5
    1.14.13.244  phenol 2-monooxygenase (NADH)
     K16246  dmpP, poxF, tomA5; phenol/toluene 2-monooxygenase (NADH) P5/A5

Other DBs

COG:	COG0543 COG0633

Genes

PSD:

DSC_04415

RTH:	LRK53_10245

RBD:

ALSL_0896

PRE:	PCA10_07010(dmpP)

PFUW:

KF707C_6740(dmpP)

PCQ:	PcP3B5_25350(dmpP)

PPG:	PputGB1_3306

PPJ:	RK21_04242

PVR:	PverR02_14680

PKC:	PKB_1746(dmpP)

PALK:

PSAKL28_05920

PALL:

UYA_20180

PUM:	HGP31_14990

PLAL:

FXN65_03435

PPHN:

HU825_04995

PIZ:	LAB08_R22530

PKM:	PZ739_17290

PKK:	QQ992_10235

PTRL:

OU419_14775

PLAU:

I0D68_00675

AVN:	Avin_08810(dmpP) Avin_30710(lapP)

AVL:	AvCA_08810(dmpP) AvCA_30710(lapP)

AVD:	AvCA6_08810(dmpP) AvCA6_30710(lapP)

HPEG:

HAES:

PPHA:

MAD:

MSR:	AU15_09305 AU15_20690

MLQ:	ASQ50_09240

MSQ:	BKP64_13875

MARJ:

MARI_05380(dmpP)

MALL:

PBN92_01645

MSHE:

MAALD49_03380(mphP) MAALD49_03810(mphP)

MANP:

EHN06_02420

PSPG:

AK823_07300

PSYG:

AK825_07395

ABK:	LX00_05865

ABAU:

IX87_04560

ACC:	BDGL_000470(mphP)

ALC:	OTEC02_12965

ASEI:

I8T81_12980

ACD:	AOLE_13320

AJO:	RZ95_18640

ACW:	A0J50_11620

ALA:	BFG52_11020

ADV:	DJ533_01815 DJ533_11015

AWU:	BEN71_12705

AGU:	AS4_16410(dsoF)

ABER:

BSR55_16110

ACHI:

CDG60_14320

ATG:	J4G44_06385

ACIE:

ACIG:

MCAH:

AFUS:

CZA:	CYCME_2107

BLEP:

THIS:

TBN:

MARS:

MGEO:

MSEC:

MRZ:	KDW95_03655

NCU:	F0U83_03025

NJP:	NEJAP_0667(dmpP)

NIK:	F5I99_10130

AJP:	AMJAP_3006(dmpP)

SINI:

GT972_13700

NZO:	SAMEA4504057_0442(mphP)

NCI:	NCTC10296_00919(mphP)

NWD:	H3L96_04785

NDU:	LVJ88_00570

VFF:	VITFI_CDS1386

PTES:

JQU52_04840

USU:	LVJ78_03640

AQL:	BXU06_12775 BXU06_16840

RPI:

Rpic_4626

RPF:	Rpic12D_3550

RPJ:	N234_08130

REH:	H16_B0544(poxF)

CNC:	CNE_2c04900(poxF)

REU:	Reut_A1704 Reut_B5685

RME:	Rmet_1326(tomA5) Rmet_1782(phyE)

CBW:	RR42_s2488

CCUP:

BKK81_27070

CUP:	BKK80_29250

CUU:	BKK79_35200

COX:	E0W60_07755

CCAX:

KZ686_09965

CUK:	KB879_20170

CNAN:

A2G96_22750

BVI:	Bcep1808_7598

BUR:	Bcep18194_B2966

BCEN:

DM39_4839(dmpP)

BCT:

GEM_5408

BCED:

DM42_4998(dmpP)

BCON:

NL30_24625

BDF:	WI26_15960

BTEI:

BPSL:

BSTL:

BANN:

BAEN:

BYI:	BYI23_C000520

BUE:	BRPE67_CCDS12550

BUZ:	AYM40_16195

PARB:

PTER:

PPAI:

PHUN:

PPK:	U875_01925

PRB:	X636_07545

CABK:

NK8_49980

LIMN:

HKT17_03880

BOJ:	CBF45_04540

APES:

FOC84_00355

CDN:	BN940_04341

AFA:	UZ73_17855

AFQ:

AFA_08540

AAQU:

D3M96_09760

AAMM:

FE795_07755

PIG:	EGT29_26535

KGY:	EHF36_04925

RLH:	MIZ03_0644 MIZ03_1016

AJS:

ACID:

ACIP:

ACIN:

ACIS:

AMON:

VEI:

VBO:	CKY39_28530

VAV:	IG196_08105

CTT:	CtCNB1_3157

COF:	FOZ74_08275

ADN:	Alide_0328

ADK:	Alide2_0275

OTD:	J1M35_00080

HYL:	LPB072_18150

HPSE:

HPF_01905(dmpP)

HYN:	F9K07_02720

HTN:	KI616_01995

DIH:	G7047_01705

DRG:	H9K76_11610

SIMP:

C6571_13590

MELA:

C6568_07885

MJE:	LVC68_00975

STHM:

IS481_10500

SAQA:

OMP39_09080

MPT:	Mpe_A2280(dmpP)

METP:

C1M51_06275

SNN:	EWH46_19245

SMIO:

CATMQ487_04170(mphP_1)

IDC:	LRM40_19535

LCH:

Lcho_3358

MASW:

AM586_18630

MLIR:

LPB04_16095

TMJ:	P0M04_30685

RBU:	PG1C_06885

DAR:

Daro_3792

DEY:	HYN24_14250

DDEN:

KI615_16920

DECH:

GBK02_02800

QAU:	KI612_13860

FLE:	KI610_15500

AZO:	azo1850(lapP) azo2439(poxF)

AOA:	dqs_2000 dqs_2583

AZD:	CDA09_10275 CDA09_10430

AZR:	CJ010_12215 CJ010_15245

TMZ:	Tmz1t_3111

THU:	AC731_001785

THAU:

C4PIVTH_2797(dmpP)

THK:	CCZ27_04555 CCZ27_10685 CCZ27_10780

THAG:

CKCBHOJB_01543(dmpP)

AZQ:	G3580_00490 G3580_08230

STEG:

QA637_22950

MTUN:

MTUNDRAET4_3886(dmpP)

MAAD:

AZF01_11220

MLUT:

JET14_11665

SMY:	BJP26_18690

SHAN:

PPZ50_08295

SJP:	SJA_C1-12030(tomA5)

SINB:

SIDU_08250

SYB:	TZ53_09090

SUFL:

FIL70_18925

SBAR:

H5V43_20575

ACIB:

ACBT_0275(dmpP)

AFC:	AFAEC_1853(dmpP)

AAQI:

AAQM_0974(dmpP)

ACLO:

ACLO_a0150(dmpP)

ADZ:	ADFLV_2564(dmpP)

ARC:

ABLL_2455

AROS:

NJU99_01615

ALK:	ALEK_0375(dmpP)

AANA:

AANAER_1250(dmpP)

SAY:	TPY_0634(benC)

SAP:	Sulac_3005

MSA:	Mycsm_01968

MHIB:

MHIB_39890(mphP)

ROZ:	CBI38_31750 CBI38_32160 CBI38_32255

GOQ:	ACH46_03545

GOC:	CXX93_06750

GAM:	GII34_22040

GSI:	P5P27_15490

TOY:	FO059_13985

CCYC:

SCMU_04650(mphP)

JTE:	ASJ30_00080

JLI:	EXU32_15385

JME:	EEW87_015385

JAY:	H7A72_00080

JCR:	O9K63_12565

PHW:	G7075_13205

AUS:	IPK37_11640

RAIN:

Rai3103_07175

TCU:

Tcur_0530

AACD:

LWP59_26105 LWP59_38095

ARHD:

VSH64_31590

PDX:

Psed_0766

PSUU:

Psuf_068280(mphP)

COY:	HF329_27145

CFIL:

MYF79_02125

CHOR:

MKQ68_23840

CPOL:

WJU16_14970

NKF:	Nkreftii_004063

AG:	BAA23335(dsoF)

» show all

Reference

PMID:2254258

Authors

Nordlund I, Powlowski J, Shingler V

Title

Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600.

Journal

J Bacteriol 172:6826-33 (1990)
DOI:10.1128/jb.172.12.6826-6833.1990

Sequence

[ppj:RK21_04242]

Reference

PMID:11751810

Authors

Canada KA, Iwashita S, Shim H, Wood TK

Title

Directed evolution of toluene ortho-monooxygenase for enhanced 1-naphthol synthesis and chlorinated ethene degradation.

Journal

J Bacteriol 184:344-9 (2002)
DOI:10.1128/jb.184.2.344-349.2002

Sequence

[bvi:Bcep1808_7598]

All links

Ontology (4)   
   KEGG BRITE (2)   
   COG (2)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical reaction (8)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
   KEGG RCLASS (2)   
Gene (747)   
   KEGG GENES (245)   
   KEGG MGENES (413)   
   RefGene (88)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (774)   

Download RDF

ORTHOLOGY: K16245

Entry

K16245                      KO

Symbol

dmpO, poxE, tomA4

Name

phenol/toluene 2-monooxygenase (NADH) P4/A4 [EC:1.14.13.244 1.14.13.243]

Pathway

map00361

Chlorocyclohexane and chlorobenzene degradation

map00362

Benzoate degradation

map00623

Toluene degradation

map01100

Metabolic pathways

map01120

Microbial metabolism in diverse environments

map01220

Degradation of aromatic compounds

Module

M00548

Benzene degradation, benzene => catechol

Reaction

R03560

toluene,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R03608

o-cresol,NADH:oxygen oxidoreductase (2,3-dihydroxylating)

R10042

benzene,NADH:oxygen oxidoreductase

R10043

phenol,NADH:oxygen oxidoreductase (2-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16245  dmpO, poxE, tomA4; phenol/toluene 2-monooxygenase (NADH) P4/A4
   00361 Chlorocyclohexane and chlorobenzene degradation
    K16245  dmpO, poxE, tomA4; phenol/toluene 2-monooxygenase (NADH) P4/A4
   00623 Toluene degradation
    K16245  dmpO, poxE, tomA4; phenol/toluene 2-monooxygenase (NADH) P4/A4
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.243  toluene 2-monooxygenase
     K16245  dmpO, poxE, tomA4; phenol/toluene 2-monooxygenase (NADH) P4/A4
    1.14.13.244  phenol 2-monooxygenase (NADH)
     K16245  dmpO, poxE, tomA4; phenol/toluene 2-monooxygenase (NADH) P4/A4

Genes

PSD:

DSC_04420

RTH:	LRK53_10155

RBD:

ALSL_0897

PRE:	PCA10_07000(dmpO)

PFUW:

KF707C_6730(dmpO)

PCQ:	PcP3B5_25340

PPG:	PputGB1_3307

PPJ:	RK21_04243

PVR:	PverR02_14675

PKC:

PKB_1745

PALK:

PSAKL28_05910

PALL:

UYA_20185

PUM:	HGP31_14985

PLAL:

FXN65_03430

PPHN:

HU825_05000

PIZ:	LAB08_R22520

PKM:	PZ739_17295

PKK:	QQ992_10230

PTRL:

OU419_14780

PLAU:

I0D68_00680

AVN:	Avin_08820(dmpO) Avin_30720(lapO)

AVL:	AvCA_08820(dmpO) AvCA_30720(lapO)

AVD:	AvCA6_08820(dmpO) AvCA6_30720(lapO)

HPEG:

HAES:

PPHA:

MAD:

MSR:	AU15_20695

MLQ:	ASQ50_09245

MSQ:	BKP64_13880

MARJ:

MARI_05370

MALL:

PBN92_01640

MSHE:

MAALD49_03370(mphO) MAALD49_03800(mphO)

MANP:

EHN06_02415

PSPG:

AK823_07305

PSYG:

AK825_07400

ABK:	LX00_05870

ABAU:

IX87_04555

ACC:	BDGL_000471(mphO)

ALC:	OTEC02_12960

ASEI:

I8T81_12975

ACD:	AOLE_13315

AJO:	RZ95_18645

ACW:	A0J50_11615

ALA:	BFG52_11015

ADV:	DJ533_01820 DJ533_11010

AWU:	BEN71_12700

AGU:	AS4_16420(dsoE)

ABER:

BSR55_16105

ACHI:

CDG60_14315

ATG:	J4G44_06380

ACIU:

ACIE:

ACIG:

MCAH:

AFUS:

CZA:	CYCME_2108

BLEP:

THIS:

TBN:

MARS:

MGEO:

MSEC:

MRZ:	KDW95_03650

NCU:	F0U83_03020

NJP:	NEJAP_0666(dmpO)

NIK:	F5I99_10135

AJP:	AMJAP_3007(dmpO)

SINI:

GT972_13695

NZO:	SAMEA4504057_0441

NCI:	NCTC10296_00920

NWD:	H3L96_04790

NDU:	LVJ88_00565

VFF:	VITFI_CDS1385

PTES:

JQU52_04835

USU:	LVJ78_03635

AQL:	BXU06_12770 BXU06_16835

RPI:

Rpic_4627

RPF:	Rpic12D_3551

RPJ:	N234_08125

REH:	H16_B0543(poxE)

CNC:	CNE_2c04890(poxE)

REU:	Reut_A1703 Reut_B5684

RME:	Rmet_1327(tomA4) Rmet_1783(phyD)

CBW:	RR42_s2489

CCUP:

BKK81_27065

CUP:	BKK80_29255

CUU:	BKK79_35205

COX:	E0W60_07750

CCAX:

KZ686_09960

CUK:	KB879_20165

CNAN:

A2G96_22745

BVI:	Bcep1808_7597

BUR:	Bcep18194_B2967

BCEN:

DM39_4840(phO)

BCT:

GEM_5409

BCED:

DM42_4999(phO)

BCON:

NL30_24630

BDF:	WI26_15955

BTEI:

BPSL:

BSTL:

BANN:

BAEN:

BYI:	BYI23_C000530

BUE:	BRPE67_CCDS12540

BUZ:	AYM40_16200

PARB:

PTER:

PPAI:

PHUN:

PPK:	U875_01930

PRB:	X636_07540

CABK:

NK8_49970

LIMN:

HKT17_03885

BOJ:	CBF45_04545

APES:

FOC84_00360

CDN:	BN940_04346

AFA:	UZ73_17850

AFQ:

AFA_08535

AAQU:

D3M96_09755

AAMM:

FE795_07750

PIG:	EGT29_26540

KGY:	EHF36_04930

RLH:	MIZ03_0643 MIZ03_1015

AJS:

ACID:

ACIP:

ACIN:

ACIS:

AMON:

VEI:

VAV:	IG196_08100

CTT:	CtCNB1_3158

COF:	FOZ74_08270

ADN:	Alide_0327

ADK:	Alide2_0274

OTD:	J1M35_00085

HYL:	LPB072_18145

HPSE:

HPF_01910(tbuD)

HYN:	F9K07_02715

HTN:	KI616_02000

DIH:	G7047_01710

DRG:	H9K76_11605

SIMP:

C6571_13585

MELA:

C6568_07890

MJE:	LVC68_00970

STHM:

IS481_10495

SAQA:

OMP39_09075

MPT:	Mpe_A2281(dmpO) Mpe_A3305(dmpO)

METP:

C1M51_06255 C1M51_06280 C1M51_15440

SNN:	EWH46_19250

SMIO:

CATMQ487_04180(mphO)

IDC:	LRM40_19530

LCH:

Lcho_3359

MASW:

AM586_18625

MLIR:

LPB04_16100

TMJ:	P0M04_30690

RBU:	PG1C_06890

DAR:

Daro_3793

DEY:	HYN24_14140 HYN24_14255

DDEN:

KI615_16925

DECH:

GBK02_02795

QAU:	KI612_13865

FLE:	KI610_15390 KI610_15505

AZO:	azo1849(lapO) azo2440(poxE)

AOA:	dqs_1999 dqs_2584

AZD:	CDA09_10270 CDA09_10425

AZR:	CJ010_12210 CJ010_15250

TMZ:	Tmz1t_3112

THU:	AC731_001780

THAU:

C4PIVTH_2796(dmpO)

THK:	CCZ27_10680 CCZ27_10785

THAG:

CKCBHOJB_01542

AZQ:	G3580_00485 G3580_01310 G3580_08225

MTUN:

MTUNDRAET4_3885

MAAD:

AZF01_11215

MLUT:

JET14_11660

SMY:	BJP26_18685

SHAN:

PPZ50_08290

SJP:	SJA_C1-12020(tomA4)

SINB:

SIDU_08255

SYB:	TZ53_09085

SUFL:

FIL70_18930

SBAR:

H5V43_20580

ACIB:

ACBT_0276(dmpO)

AFC:	AFAEC_1854(dmpO)

AAQI:

AAQM_0973(dmpO)

ACLO:

ACLO_a0151(dmpO)

ADZ:	ADFLV_2565(dmpO)

ARC:

ABLL_2456

AROS:

NJU99_01610

ALK:	ALEK_0374(dmpO)

AANA:

AANAER_1249(dmpO)

AUD:	PO771_08955

SAY:

TPY_0631

SAP:	Sulac_3008

MSA:	Mycsm_01967

MLL:	B1R94_25100

GOQ:	ACH46_03540

GOC:	CXX93_06745

GAM:	GII34_22045

GSI:	P5P27_15495

TOY:	FO059_13980

JTE:	ASJ30_00075

JLI:	EXU32_15390

JME:	EEW87_015380

JCR:	O9K63_12560

PHW:	G7075_13210

AUS:	IPK37_11625

TCU:

Tcur_0527

AACD:

LWP59_26110 LWP59_38100

ARHD:

VSH64_31595

PDX:

Psed_0767

AG:	BAA23334(dsoE)

» show all

Reference

PMID:2254258

Authors

Nordlund I, Powlowski J, Shingler V

Title

Complete nucleotide sequence and polypeptide analysis of multicomponent phenol hydroxylase from Pseudomonas sp. strain CF600.

Journal

J Bacteriol 172:6826-33 (1990)
DOI:10.1128/jb.172.12.6826-6833.1990

Sequence

[ppj:RK21_04243]

Reference

PMID:11751810

Authors

Canada KA, Iwashita S, Shim H, Wood TK

Title

Directed evolution of toluene ortho-monooxygenase for enhanced 1-naphthol synthesis and chlorinated ethene degradation.

Journal

J Bacteriol 184:344-9 (2002)
DOI:10.1128/jb.184.2.344-349.2002

Sequence

[bvi:Bcep1808_7597]

All links

Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (12)   
   KEGG MODULE (1)   
Chemical reaction (8)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
   KEGG RCLASS (2)   
Gene (513)   
   KEGG GENES (237)   
   KEGG MGENES (232)   
   RefGene (42)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (538)   

Download RDF

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