KEGG   ORTHOLOGY: K16422
Entry
K16422                      KO                                     
Symbol
hmo, nocN
Name
4-hydroxymandelate oxidase [EC:1.1.3.46]
Pathway
map00261  Monobactam biosynthesis
map01055  Biosynthesis of vancomycin group antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01055 Biosynthesis of vancomycin group antibiotics
    K16422  hmo, nocN; 4-hydroxymandelate oxidase
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    K16422  hmo, nocN; 4-hydroxymandelate oxidase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16422  hmo, nocN; 4-hydroxymandelate oxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.3  With oxygen as acceptor
    1.1.3.46  4-hydroxymandelate oxidase
     K16422  hmo, nocN; 4-hydroxymandelate oxidase
Polyketide biosynthesis proteins [BR:ko01008]
 Nonribosomal peptide tailoring proteins
  Others
   K16422  hmo, nocN; 4-hydroxymandelate oxidase
Other DBs
RN: R06633
Genes
EBI: EbC_45010
PAO: Pat9b_0059
KLN: LH22_02000
PANS: FCN45_00295
PSUW: WQ53_04950
XBA: C7S18_07265
PMY: Pmen_0804
PRE: PCA10_09820(lldD)
PPSE: BN5_0696(glcD3)
PFUW: KF707C_9130
PSET: THL1_1034
PALL: UYA_03960
POJ: PtoMrB4_11440
PLAL: FXN65_04550
PKH: JLK41_04285
PNN: KEM63_07345
PWZ: J7655_03835
PHF: NLY38_04070
AVN: Avin_12350(lldD)
AVL: AvCA_12350(lldD)
AVD: AvCA6_12350(lldD)
ACX: Achr_30250(lldD)
EMO: DM558_00105
EAZ: JHT90_12855
HAES: LO767_01930
PSYY: DLE54_06755 DLE54_06980
ATT: AMQ28_05560
AEI: AOY20_01775
AJO: RZ95_14500
AHL: AHTJS_02455
ASJ: AsACE_CH00433
AID: CTZ23_02310
ADV: DJ533_16435
AWU: BEN71_03430
ACUM: C9E88_006515
AGU: AS4_05470
ADS: FPL17_16865
ABER: BSR55_17750
ACHI: CDG60_15615
ASHA: G8E00_02820
ATG: J4G44_00650
ABOU: ACBO_26740
SPOL: FH971_10065
SKH: STH12_02859(lldD)
SDK: KHX94_16705
PTU: PTUN_a4088(glcD)
PMES: FX988_00687
ALKM: NKI27_10730
ZAL: AZF00_16215
LFA: LFA_1216(GLO)
LHA: LHA_0501
CYY: CPC19_11350
TXA: HQN79_00810
THIS: HZT40_14725
TWN: L2Y54_11885
GAI: IMCC3135_25780(hmo)
HCH: HCH_01681
HAHE: ENC22_22225
HHH: CLM76_06065
KAK: Kalk_08620
MARS: A8C75_03950
MRZ: KDW95_12225
NCU: F0U83_13850
GSN: YC6258_04793
SINI: GT972_11345
SALN: SALB1_1045
VFF: VITFI_CDS3216
VIT: ADP71_31350
VST: LVJ81_12130
VMS: LVJ82_08190
AQL: BXU06_07955
VOG: LCH97_08320
CGD: CR3_3245(glcD)
CPAU: EHF44_23235
CCAX: KZ686_18395
BGU: KS03_3471
BPLA: bpln_1g26350
PMEG: FNZ07_25555
PUS: CKA81_03480
PUD: G9Q38_09430
AFA: UZ73_08085
AFQ: AFA_02405
AAMM: FE795_02370
OUR: CEQ07_08655
OUE: I6G29_10405
PIG: EGT29_20715
PACR: FXN63_21860
RHY: RD110_19630
ACK: C380_14255
ACRA: BSY15_3965
ACID: CBP33_11150
ACIP: CBP36_11075
ACIN: CBP34_10980
ACIS: CBP35_07855
ACIO: EAG14_07140
AMON: H9L24_02175
AANT: HUK68_11660
ARAD: KI609_10130
DTS: BI380_00615
DHK: BO996_20975
DLA: I6G47_01340
CKE: B5M06_07315
CSER: CCO03_11830
COF: FOZ74_09250
CAQT: KAQ61_14740
CODO: LAD35_07210
OTK: C6570_07945
LIH: L63ED372_01067(lldD_1)
HYR: BSY239_2087
HYB: Q5W_00125
HYL: LPB072_15815
HYC: E5678_07245
HPSE: HPF_09820
HYN: F9K07_18330
HTN: KI616_14805
HCZ: G9Q37_19195
DPY: BA022_12275
DIH: G7047_00230
DAER: H9K75_17485
DRG: H9K76_18230
SIMP: C6571_16290
MELM: C7H73_03560
MELA: C6568_06065
MJE: LVC68_02580
KIA: G8A07_26140
STHM: IS481_00890
SAQA: OMP39_00445
RGE: RGE_43910
SNN: EWH46_04875
ATER: MW290_15185
MASS: CR152_05310
MANC: IV454_11370
UND: UNDKW_2976
PKT: AT984_17325
AON: DEH84_01955
TTW: LCC91_03490
BBAY: A4V04_09650
NST: Nstercoris_01156
METR: BSY238_10
MEU: ACJ67_12165
SNIV: SFSGTM_20120
AIQ: Azoinq_10760
RBU: PG1C_09700
OTR: OTERR_15390(lldD)
DDEN: KI615_16175
QAU: KI612_03440
FLE: KI610_05585
AOA: dqs_0678
THU: AC731_012105
THK: CCZ27_15025
AZQ: G3580_15095
ACOM: CEW83_18180
ZPA: C3497_07680
AELL: AELL_0874
ASUI: ASUIS_0518
ACLO: ACLO_0849
AVP: AVENP_0617
DVL: Dvul_0528
DVG: Deval_2571
DFI: AXF13_09095
DPG: DESPIGER_1501
DFL: DFE_2112
DSD: GD606_16625
DMA: DMR_21260
DCB: C3Y92_10185
DGG: DGI_1415
DDE: Dde_0750
DMS: E8L03_10940
DSA: Desal_1465
DHY: DESAM_22812
DAS: Daes_2493
DEJ: AWY79_15335
PSEL: GM415_08775 GM415_17505
DSX: GD604_14390
DBA: Dbac_1976
DPS: DP0843
DPR: Despr_0716
DEO: CAY53_04955
DOG: HP555_00960
DAT: HRM2_41110
DALK: DSCA_14510
DLI: dnl_38430
AGE: AA314_00340
AVM: JQX13_15815 JQX13_32715
MBD: MEBOL_001680
CFUS: CYFUS_002912 CYFUS_008761
SCL: sce7671
SCU: SCE1572_44330
PAUU: E8A73_024105
LLU: AKJ09_10055
MRM: A7982_09601
HOH: Hoch_0089
HOE: IMCC20628_00688
PLA: Plav_0378
NWI: Nwi_0702
TRB: HB776_09700
BOP: AXW83_15230
AZC: AZC_1619
ANC: GBB76_07300
APRA: G3A50_03145
HNI: W911_04290
RHZ: RHPLAN_58200 RHPLAN_67990
CAEN: K5X80_04840
YTI: FNA67_17300
MPAR: F7D14_11785
NOH: G5V57_17935
KRO: BVG79_01849(glcD)
PABY: Ga0080574_TMP356
SULD: B5M07_08410
SPOT: G6548_05240
SINL: DSM14862_02055(hmo)
SAGU: CDO87_26325
LSAL: KBK07_09835
PDE: Pden_4676
PPAN: ESD82_02735
PMEH: JWJ88_16220
PSHQ: F3W81_12270
NAR: Saro_0774
NRE: BES08_00445
NOV: TQ38_005445
SWI: Swit_4251
SPAN: AWL63_11515
SPHA: D3Y57_07445
RGI: RGI145_05600
ROS: CTJ15_11790
RMUC: FOB66_07430
RMT: IAI58_21860
SVC: STVA_32270
ALI: AZOLI_p20485
ABS: AZOBR_p1110093
ABQ: ABAZ39_15315
ABF: AMK58_20855
ATI: AL072_18250
AZT: TSH58p_26095
AZM: DM194_19930
AARE: D3093_20250
SMUC: JL100_019020
SROE: JL101_017820
HTL: HPTL_0509
LAD: LA14_1588
LAF: SD55_1597
LAM: LA2_08960
LAI: LAC30SC_08600
LAY: LAB52_07995
LKE: WANG_0215
LJE: BUE77_00305
CPE: CPE1878
CPF: CPF_2132
CPR: CPR_1844
CLJ: CLJU_c34360
CLS: CXIVA_13840(LldD)
CAH: CAETHG_1336
CSQ: CSCA_4771
CACE: CACET_c16820(lldD)
CCK: Ccar_17325
CARG: RSJ17_08045
CDRK: B9W14_21015
CFER: D4Z93_04370
AOE: Clos_1159
GFE: Gferi_07105
HHW: NCTC503_02011(lldD)
CALE: FDN13_03910
CRS: FQB35_00670
SARJ: HH195_07595 HH195_11630
CCL: Clocl_0919
RBP: B6259_09280
CCE: Ccel_2344
RHER: EHE19_004325
RAL: Rumal_2056
FPR: FP2_21160
FPA: FPR_06650
FPRA: CG447_04040
CCOM: I6K69_07045
CSCI: HDCHBGLK_02317(hmo)
ACAC: EYQ97_08425
EHL: EHLA_0737
RGN: RGna_01260
PDC: CDIF630_01416 CDIF630_02628
CDC: CD196_1125 CD196_2228
CDL: CDR20291_1103 CDR20291_2274
PDF: CD630DERM_12630 CD630DERM_23870
CST: CLOST_1147
PSOR: RSJ16_14275
ROC: HF520_09305
PHX: KGNDJEFE_01524(hmo)
DOR: Desor_5480
DAI: Desaci_4587
DMI: Desmer_4518
DED: DHBDCA_p1237
DEC: DCF50_p1303
DCA: Desca_1949
DRM: Dred_1257
DRU: Desru_2825
DFG: B0537_05970
DKU: Desku_2803
TFR: BR63_01350
HCV: FTV88_0031
AWO: Awo_c03770
ACAE: HYG86_06340
CTHM: CFE_0998
MDV: C5Q96_08410
EUU: ADJ67_06690
CHY: CHY_0269 CHY_1319
ADG: Adeg_1075
GEK: kuro4_13110
COB: COB47_2205
CKN: Calkro_0254
CCHA: ELD05_12315
TSH: Tsac_2535
TNR: Thena_1632
TACI: TDSAC_1603
TEP: TepRe1_1797
TAE: TepiRe1_1937
TOC: Toce_0633
NTH: Nther_2031
KME: H0A61_01190(hmo)
KPAR: JL105_01275
MED: MELS_0352
MEG: DKB62_02690
PUF: UFO1_4337
STED: SPTER_33280(lldD)
AIN: Acin_0831
AARG: Aargi30884_12510
ABSI: A9CBEGH2_13410
LCG: L3BBH23_07350
ERB: A4V01_07355
CIU: G4D55_06025
NBR: O3I_010580
NTP: CRH09_30885
NOZ: DMB37_31330
NAH: F5544_09030 F5544_26845
RHB: NY08_2291
RPSK: JWS13_19495
TPR: Tpau_3076
TSM: ASU32_06245
TPUL: TPB0596_35140
SCO: SCO3228(SCE63.05)
SGB: WQO_12235
SVL: Strvi_5274 Strvi_8790
SHY: SHJG_8441
SHO: SHJGH_8202
SRC: M271_09165 M271_27675 M271_46055
SMAL: SMALA_0360
SSOI: I1A49_05315
SBH: SBI_01125 SBI_04778
SLV: SLIV_21550
STRE: GZL_08686
SLC: SL103_26565
STRC: AA958_31845
SAMB: SAM23877_5651
SRW: TUE45_pSRc_0230(TUE45_pSRTUE45c_0230)
STRF: ASR50_31315
SPAV: Spa2297_02910 Spa2297_26640 Spa2297_32980
STRT: A8713_31370
SKY: D0C37_28255
SALW: CP975_03175 CP975_31960 CP975_31975 CP975_34475
SGM: GCM10017557_81720
SNR: SNOUR_39380 SNOUR_40635
SALU: DC74_564
SALL: SAZ_03315
SPLU: LK06_031590
SAUO: BV401_05560
SSIA: A7J05_00250 A7J05_04110 A7J05_36485
SVU: B1H20_11470
SLAU: SLA_6885
SALF: SMD44_00061(glcD)
STRO: STRMOE7_29125
SFK: KY5_6264c KY5_6713 KY5_7436c
SRJ: SRO_7148
SCYA: EJ357_01685
SKA: CP970_03000 CP970_03015 CP970_07080 CP970_09765
SVR: CP971_02375 CP971_08180
SFY: GFH48_02895 GFH48_36330
SGF: HEP81_07478
SBY: H7H31_03485
SRIM: CP984_06505 CP984_27455 CP984_39205
SFUG: CNQ36_25595
STSU: B7R87_00115
SCHA: CP983_01450 CP983_10835
SGX: H4W23_38360
SSPB: CP982_05960 CP982_06170
STUI: GCM10017668_03330
SCYG: S1361_20500
SFEU: IM697_27410
SCAL: I6J39_11675
SAUH: SU9_002085
SANU: K7396_35160
SINE: KI385_01580
SDUR: M4V62_39090
SRUG: F0345_27910
SNIG: HEK616_29500 HEK616_51640
KSK: KSE_65170 KSE_67420
KAB: B7C62_11140
KAU: B6264_28340
KIT: CFP65_1219
KIS: HUT16_30910 HUT16_31115 HUT16_31830
STRH: GXP74_15535 GXP74_26120 GXP74_29210
ABRY: NYE86_02910
RFS: C1I64_00520
FRP: AX769_15450
LMOI: VV02_16505
YIM: J5M86_08715
ALX: LVQ62_10700
XYA: ET471_17455
CFL: Cfla_2130
CDON: KKR89_10780
CWAN: KG103_10905
SERJ: SGUI_0332
NCA: Noca_1980
NDK: I601_3731(lldD_2)
NOY: EXE57_04390
NOO: FE634_08345
NANO: G5V58_08260
NAQU: ENKNEFLB_02043(hmo)
NPS: KRR39_10975
AER: AERYTH_16755
AEZ: C3E78_17710
AEF: GEV26_17485
KFL: Kfla_6052 Kfla_6167
KQI: F1D05_14905 F1D05_15510
AGRA: AGRA3207_000911
NOA: BKM31_54210
NOW: GBF35_33890
NCX: Nocox_13260(noc1)
NGN: LCN96_07785
FRA: Francci3_2463
FRE: Franean1_3511
FRI: FraEuI1c_3200
FAL: FRAAL3814
NML: Namu_3188
BSD: BLASA_0395(Hao) BLASA_2148(hao2)
MMAR: MODMU_3504(Hao)
KRA: Krad_2981
AMD: AMED_0893
AMN: RAM_04555
AMM: AMES_0890
AMZ: B737_0891
AOI: AORI_1496(glcD)
AJA: AJAP_32035
AMYC: CU254_03020
AMYB: BKN51_41525
AMYY: YIM_21185
AORI: SD37_16615 SD37_33640
AACD: LWP59_10735
APRT: MUY14_32325
AROO: NQK81_15405
APRE: CNX65_20200
AMI: Amir_4034 Amir_4598
SSYI: EKG83_30070 EKG83_30930
KAL: KALB_6131
KPHY: AOZ06_37045
ACTI: UA75_15340
ACAD: UA74_14770
ACTA: C1701_23445
STP: Strop_2478
SAQ: Sare_0496 Sare_2661
MAU: Micau_3468
MIL: ML5_4923
MICB: MicB006_2522 MicB006_2968
MTUA: CSH63_07705 CSH63_12375
MICH: FJK98_14210 FJK98_16505
MTEM: GCE86_13310
MCAB: HXZ27_13965 HXZ27_18275
MSAG: GCM10017556_53930
VMA: VAB18032_22225 VAB18032_24785
VER: HUT12_12305
ACTN: L083_5468 L083_7109
AFS: AFR_01595 AFR_37575
ACTS: ACWT_2064
ACTR: Asp14428_12750 Asp14428_15790
PFLA: Pflav_007660
PSUU: Psuf_064700 Psuf_086480
ATL: Athai_14010 Athai_22660
ASER: Asera_47800 Asera_52290
PRY: Prubr_36980 Prubr_65040
CATI: CS0771_77030
DVC: Dvina_13750 Dvina_17890 Dvina_20420 Dvina_38790
DFU: Dfulv_12390
DAUR: Daura_12875 Daura_31180
DMAT: Dmats_13285 Dmats_33750
NHY: JQS43_15560
CCAZ: COUCH_38130
CAI: Caci_3265 Caci_4107
SNA: Snas_1502
BTP: D805_1170
JTL: M6D93_03240
ABAI: IMCC26256_11496
RXY: Rxyl_2999
PARN: NBH00_16110 NBH00_19215
SBAE: DSM104329_02733(hmo_2)
ERZ: ER308_09970
HHG: XM38_038450(hmo)
PSER: ABRG53_a068 ABRG53_a072
CYT: cce_1717
CYJ: Cyan7822_5209
TER: Tery_2398
MIC: Mic7113_4887
MPRO: BJP34_25760
CEP: Cri9333_3045
ANA: all0170
NPU: Npun_R5717
NOS: Nos7107_4571
NOP: Nos7524_4202
NON: NOS3756_46730
NFL: COO91_03705
NOE: CLI64_13360
NSH: GXM_03321
NED: HUN01_27595
AVA: Ava_1430
ANB: ANA_C12655
ANN: EH233_27075
CSG: Cylst_0380
RSIN: B6N60_01287
CALO: Cal7507_4047
CALH: IJ00_16930
CALN: NIES2098_15540
DOU: BMF77_03099(hmo)
DFS: HGD76_08665
AFLO: HEQ12_14100
TOQ: HCG51_14550
NCN: BZZ01_30295
CTHE: Chro_0042
PLP: Ple7327_3868
STAN: STA3757_22630
HAU: Haur_0229 Haur_1871
PBF: CFX0092_A1841
KBS: EPA93_04875 EPA93_25295 EPA93_37090
DGE: Dgeo_2057
DDR: Deide_15560
DCH: SY84_09605
DAB: AUC44_00610
DPU: SU48_02005
DWU: DVJ83_02750
DFC: DFI_08470
DEIN: DAAJ005_04280
DGA: DEGR_01180
DAH: DAETH_27050
TRA: Trad_2342
VBH: CMV30_13800
OBT: OPIT5_09870
LUO: HHL09_02440
LAMB: KBB96_19135
TIM: GMBLW1_07500
TPI: TREPR_3177
TRI: DYE50_00095
SSM: Spirs_1471
TAZ: TREAZ_3083
BPO: BP951000_1638
BPJ: B2904_orf2334
BPIP: BPP43_07045
BPW: WESB_0467
BHP: BHAMNSH16_10970
ABAS: ACPOL_6814
SUS: Acid_1641 Acid_1779 Acid_7243
ABAC: LuPra_01597(lldD_1) LuPra_02070(lldD_2)
SCOR: J3U87_21565
FVA: FV113G1_10750
FGO: C4N16_05810 C4N16_06435
FNF: BSQ88_05685
IPO: Ilyop_0744
AMO: Anamo_1914
GAU: GAU_0248
GPH: GEMMAAP_10810 GEMMAAP_16695
GGR: HKW67_03885
GBA: J421_0641 J421_1218
PMZ: HMPREF0659_A6324
PFUS: ADJ77_07250
PJE: CRM71_07770
PHIS: J5A62_00620
PSCJ: J4856_12130
SPIK: EXU85_15990
SPIB: G8759_31000
RUN: DR864_23485
TYE: THEYE_A0075
TCM: HL41_07275
THET: F1847_08305
AG: AAT09795(nocN) CAA11762(hmo)
 » show all
Reference
PMID:11137816
  Authors
Hubbard BK, Thomas MG, Walsh CT
  Title
Biosynthesis of L-p-hydroxyphenylglycine, a non-proteinogenic amino acid constituent of peptide antibiotics.
  Journal
Chem Biol 7:931-42 (2000)
DOI:10.1016/S1074-5521(00)00043-0
  Sequence
[ag:CAA11762]
Reference
PMID:12445768
  Authors
Hojati Z, Milne C, Harvey B, Gordon L, Borg M, Flett F, Wilkinson B, Sidebottom PJ, Rudd BA, Hayes MA, Smith CP, Micklefield J
  Title
Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor.
  Journal
Chem Biol 9:1175-87 (2002)
DOI:10.1016/S1074-5521(02)00252-1
  Sequence
[sco:SCO3228]
Reference
PMID:15271351
  Authors
Gunsior M, Breazeale SD, Lind AJ, Ravel J, Janc JW, Townsend CA
  Title
The biosynthetic gene cluster for a monocyclic beta-lactam antibiotic, nocardicin A.
  Journal
Chem Biol 11:927-38 (2004)
DOI:10.1016/j.chembiol.2004.04.012
  Sequence
[ag:AAT09795]

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Gene (5819)   
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