KEGG   ORTHOLOGY: K16426
Entry
K16426                      KO                                     
Symbol
dpgD
Name
dehydration protein DpgD
Pathway
map01055  Biosynthesis of vancomycin group antibiotics
map01110  Biosynthesis of secondary metabolites
Reaction
R06625  malonyl-CoA:malonyl-CoA malonyltransferase (3,5-dihydroxyphenylacetyl-CoA-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01055 Biosynthesis of vancomycin group antibiotics
    K16426  dpgD; dehydration protein DpgD
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16426  dpgD; dehydration protein DpgD
Polyketide biosynthesis proteins [BR:ko01008]
 Nonribosomal peptide tailoring proteins
  Others
   K16426  dpgD; dehydration protein DpgD
Genes
SMAF: D781_2328
SERM: CLM71_12085
SRHZ: FO014_21625
RBAD: H2866_19120
XAL: XALC_1063
XTN: FD63_09810
XPR: MUG10_21480
SPSJ: K0I62_02765
PMEA: KTC28_01735
RFL: Rmf_16460
STEL: STAQ_46000
NAD: NCTC11293_04862(caiD_10)
SVE: SVEN_0483
KFL: Kfla_4133
NDA: Ndas_1736
NCX: Nocox_13280(noc5)
SACC: EYD13_07720(caiD2)
AOI: AORI_1505(caiD)
AMYY: YIM_22195(caiD4)
AORI: SD37_33595
ACOR: LCL61_00310(dpgD)
MSAG: GCM10017556_56580(fadB)
ACTL: L3i22_092960(fadB)
PFLA: Pflav_007990(fadB_1)
 » show all
Reference
  Authors
Xu L, Huang H, Wei W, Zhong Y, Tang B, Yuan H, Zhu L, Huang W, Ge M, Yang S, Zheng H, Jiang W, Chen D, Zhao GP, Zhao W
  Title
Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis.
  Journal
BMC Genomics 15:363 (2014)
DOI:10.1186/1471-2164-15-363
  Sequence
[aoi:AORI_1505]

KEGG   ORTHOLOGY: K16424
Entry
K16424                      KO                                     
Symbol
dpgA
Name
3,5-dihydroxyphenylacetyl-CoA synthase [EC:2.3.1.246]
Pathway
map01055  Biosynthesis of vancomycin group antibiotics
map01110  Biosynthesis of secondary metabolites
Reaction
R06625  malonyl-CoA:malonyl-CoA malonyltransferase (3,5-dihydroxyphenylacetyl-CoA-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01055 Biosynthesis of vancomycin group antibiotics
    K16424  dpgA; 3,5-dihydroxyphenylacetyl-CoA synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16424  dpgA; 3,5-dihydroxyphenylacetyl-CoA synthase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.246  3,5-dihydroxyphenylacetyl-CoA synthase
     K16424  dpgA; 3,5-dihydroxyphenylacetyl-CoA synthase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Type III PKS
   Bacterial type
    K16424  dpgA; 3,5-dihydroxyphenylacetyl-CoA synthase
Other DBs
COG: COG3424
Genes
SMAF: D781_2331
SERM: CLM71_12100
RBAD: H2866_19105
XAL: XALC_1059
XTN: FD63_09790
XPR: MUG10_21500
PAND: DRB87_09790
MNR: ACZ75_13535
BSTO: C0V70_02630
NBR: O3I_032820
SMAL: SMALA_7737
SBH: SBI_03177
SVE: SVEN_0493
SLE: sle_03950(sle_03950) sle_58620(sle_58620)
SMIB: SMIR_40380
KFL: Kfla_4132
NDA: Ndas_1740
NCX: Nocox_13295(noc8)
AOI: AORI_1502(bcsA) AORI_5330(bcsA)
AMYY: YIM_22225
AORI: SD37_33610
ACOR: LCL61_00295(dpgA)
MFEU: H1D33_24995(dpgA)
ACTL: L3i22_092840(pks18)
PRY: Prubr_65020(pks18)
AG: CAC48378(dpgA)
 » show all
Reference
  Authors
Xu L, Huang H, Wei W, Zhong Y, Tang B, Yuan H, Zhu L, Huang W, Ge M, Yang S, Zheng H, Jiang W, Chen D, Zhao GP, Zhao W
  Title
Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis.
  Journal
BMC Genomics 15:363 (2014)
DOI:10.1186/1471-2164-15-363
  Sequence
[aoi:AORI_1502]
Reference
  Authors
Pfeifer V, Nicholson GJ, Ries J, Recktenwald J, Schefer AB, Shawky RM, Schroder J, Wohlleben W, Pelzer S
  Title
A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.
  Journal
J Biol Chem 276:38370-7 (2001)
DOI:10.1074/jbc.M106580200
  Sequence

KEGG   ORTHOLOGY: K16425
Entry
K16425                      KO                                     
Symbol
dpgB
Name
isomerase DpgB
Pathway
map01055  Biosynthesis of vancomycin group antibiotics
map01110  Biosynthesis of secondary metabolites
Reaction
R06625  malonyl-CoA:malonyl-CoA malonyltransferase (3,5-dihydroxyphenylacetyl-CoA-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01055 Biosynthesis of vancomycin group antibiotics
    K16425  dpgB; isomerase DpgB
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16425  dpgB; isomerase DpgB
Polyketide biosynthesis proteins [BR:ko01008]
 Nonribosomal peptide tailoring proteins
  Others
   K16425  dpgB; isomerase DpgB
Genes
SMAF: D781_2330
SERM: CLM71_12095
SRHZ: FO014_21615
RBAD: H2866_19110
XAL: XALC_1060
XTN: FD63_09795
XPR: MUG10_21495
NBR: O3I_032815
NTP: CRH09_30865
NAD: NCTC11293_04864(scpB_2)
SMAL: SMALA_7752
SVE: SVEN_0494
SFK: KY5_7441
SMIB: SMIR_40375
KFL: Kfla_4131
NDA: Ndas_1739
NCX: Nocox_13290(noc7)
AOI: AORI_1503(paaG) AORI_5329(paaG)
AORI: SD37_33605
ACOR: LCL61_00300(dpgB)
KUT: JJ691_30270(dpgB_1) JJ691_70280(dpgB_2)
MFEU: H1D33_24990(dpgB)
 » show all
Reference
  Authors
Xu L, Huang H, Wei W, Zhong Y, Tang B, Yuan H, Zhu L, Huang W, Ge M, Yang S, Zheng H, Jiang W, Chen D, Zhao GP, Zhao W
  Title
Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis.
  Journal
BMC Genomics 15:363 (2014)
DOI:10.1186/1471-2164-15-363
  Sequence
[aoi:AORI_1503]

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