KEGG   ORTHOLOGY: K16514
Entry
K16514                      KO                                     

Name
galD
Definition
4-oxalomesaconate tautomerase [EC:5.3.2.8]
Pathway
ko00362  Benzoate degradation
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K16514  galD; 4-oxalomesaconate tautomerase
Enzymes [BR:ko01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.2  Interconverting keto- and enol-groups
    5.3.2.8  4-oxalomesaconate tautomerase
     K16514  galD; 4-oxalomesaconate tautomerase
Other DBs
RN: R07839
COG: COG2828
Genes
KPN: KPN_04047
KPU: KP1_5416
KPM: KPHS_52170
KPP: A79E_0060
KPH: KPNIH24_25955
KPZ: KPNIH27_24940
KPV: KPNIH29_25900
KPW: KPNIH30_26295
KPY: KPNIH31_25370
KPG: KPNIH32_27160
KPR: KPR_0060
KPJ: N559_0096
KPX: PMK1_01553(galD)
KPNU: LI86_00300
KPNK: BN49_0060
KVA: Kvar_0052
KPE: KPK_0046
CRO: ROD_31661
CAMA: F384_17455
SPE: Spro_2090
SMAF: D781_1917
RAA: Q7S_13295
EAM: EAMY_1951(fldA3)
EAY: EAM_1908
EBI: EbC_05340
XCC: XCC4031(fldA)
XCB: XC_4120
XCP: XCR_0229
XCV: XCV4254
XAX: XACM_4026
XAC: XAC4156(fldA)
XCI: XCAW_00142(fldA)
XOM: XOO4300(XOO4300)
XOO: XOO4563(fldA)
XOP: PXO_03236(fldA)
XOR: XOC_0385
XPH: XppCFBP6546_13625(XppCFBP6546P_13625)
PCQ: PcP3B5_13880(galD)
PPU: PP_2513(gllD)
PPI: YSA_00540
PPX: T1E_3401
PPUT: L483_20180
PPUN: PP4_26410
PFL: PFL_2685
PPRO: PPC_2729
PSTT: CH92_18155
PSOS: POS17_2676(PFL_2685)
PSIL: PMA3_18990
PAT: Patl_3889
CSA: Csal_0328
RFO: REIFOR_00530(prpF)
SALN: SALB1_0066
PSE: NH8B_2727
RSY: RSUY_46200(galD)
RME: Rmet_3706
BPH: Bphy_3209
PPNO: DA70_15090
PPNM: LV28_15590
PPUL: RO07_09635
PSPU: NA29_05550
PAPI: SG18_10135
PLG: NCTC10937_01989(mii_2)
HYF: DTO96_100888(galD)
BHO: D560_0871
BHM: D558_0857
BHZ: ACR54_03617(galD)
AFQ: AFA_05545
PNA: Pnap_2033
DAC: Daci_4451
LIM: L103DPR2_01491(galD_2)
AZO: azo2544(fldA)
AOA: dqs_2701
TCL: Tchl_1057
AMIH: CO731_01870(galD)
SME: SMc00497
SMX: SM11_chr1630(fldA)
SMER: DU99_09680
ARA: Arad_2914
RLE: RL2850
RPA: RPA4696(FldA)
RPB: RPB_0878
RPD: RPD_0988
RPE: RPE_0745
RPT: Rpal_5177
PHL: KKY_3765
MALG: MALG_02282
LABT: FIU93_13990(galD)
ROT: FIV09_09365(galD)
MALU: KU6B_25080(fldA) KU6B_53780
NAR: Saro_2818
SMAZ: LH19_17720
SPHI: TS85_18490
SSAN: NX02_17530
SSY: SLG_12560
SPHR: BSY17_3452
SFLA: SPHFLASMR4Y_02982(galD)
BLAS: BSY18_3518
AAY: WYH_01903(galD)
ADO: A6F68_01085(galD)
ALB: AEB_P0248
MAG: amb0250
MAGX: XM1_1086
MAGN: WV31_13590
MAGQ: MGMAQ_2664
MSHG: MSG_02375
SALB: XNR_3396
SFA: Sfla_3395
STRP: F750_3341(prpF)
SLE: sle_08620(sle_08620)
STRD: NI25_00245
SMAL: SMALA_0372
SGE: DWG14_01306(galD)
MLV: CVS47_03113(galD)
AMIN: AUMI_19420
AUW: AURUGA1_00416(galD)
ACH: Achl_3362
MMAR: MODMU_2828
PSEE: FRP1_23145
ACTN: L083_3806
SLI: Slin_4025
 » show all
Reference
  Authors
Nogales J, Canales A, Jimenez-Barbero J, Serra B, Pingarron JM, Garcia JL, Diaz E
  Title
Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida.
  Journal
Mol Microbiol 79:359-74 (2011)
DOI:10.1111/j.1365-2958.2010.07448.x
  Sequence
[ppu:PP_2513]

KEGG   ENZYME: 5.3.2.8
Entry
EC 5.3.2.8                  Enzyme                                 

Name
4-oxalomesaconate tautomerase;
GalD
Class
Isomerases;
Intramolecular oxidoreductases;
Interconverting keto- and enol-groups
Sysname
4-oxalomesaconate keto---enol-isomerase
Reaction(IUBMB)
(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate = (1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate [RN:R07839]
Reaction(KEGG)
R07839
Substrate
(1E)-4-oxobut-1-ene-1,2,4-tricarboxylate [CPD:C04434]
Product
(1E,3E)-4-hydroxybuta-1,3-diene-1,2,4-tricarboxylate [CPD:C04324]
Comment
This enzyme has been characterized from the bacterium Pseudomonas putida KT2440 and is involved in the degradation pathway of syringate and 3,4,5-trihydroxybenzoate. It catalyses the interconversion of two of the tautomers of 4-oxalomesaconate, a reaction that can also occur spontaneously.
History
EC 5.3.2.8 created 2011 as EC 5.3.3.16, modified 2011, transferred 2012 to EC 5.3.2.8
Pathway
ec00362  Benzoate degradation
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K16514  4-oxalomesaconate tautomerase
Genes
KPN: KPN_04047
KPU: KP1_5416
KPM: KPHS_52170
KPP: A79E_0060
KPH: KPNIH24_25955
KPZ: KPNIH27_24940
KPV: KPNIH29_25900
KPW: KPNIH30_26295
KPY: KPNIH31_25370
KPG: KPNIH32_27160
KPR: KPR_0060
KPJ: N559_0096
KPX: PMK1_01553(galD)
KPNU: LI86_00300
KPNK: BN49_0060
KVA: Kvar_0052
KPE: KPK_0046
CRO: ROD_31661
CAMA: F384_17455
SPE: Spro_2090
SMAF: D781_1917
RAA: Q7S_13295
EAM: EAMY_1951(fldA3)
EAY: EAM_1908
EBI: EbC_05340
XCC: XCC4031(fldA)
XCB: XC_4120
XCP: XCR_0229
XCV: XCV4254
XAX: XACM_4026
XAC: XAC4156(fldA)
XCI: XCAW_00142(fldA)
XOM: XOO4300(XOO4300)
XOO: XOO4563(fldA)
XOP: PXO_03236(fldA)
XOR: XOC_0385
XPH: XppCFBP6546_13625(XppCFBP6546P_13625)
PCQ: PcP3B5_13880(galD)
PPU: PP_2513(gllD)
PPI: YSA_00540
PPX: T1E_3401
PPUT: L483_20180
PPUN: PP4_26410
PFL: PFL_2685
PPRO: PPC_2729
PSTT: CH92_18155
PSOS: POS17_2676(PFL_2685)
PSIL: PMA3_18990
PAT: Patl_3889
CSA: Csal_0328
RFO: REIFOR_00530(prpF)
SALN: SALB1_0066
PSE: NH8B_2727
RSY: RSUY_46200(galD)
RME: Rmet_3706
BPH: Bphy_3209
PPNO: DA70_15090
PPNM: LV28_15590
PPUL: RO07_09635
PSPU: NA29_05550
PAPI: SG18_10135
PLG: NCTC10937_01989(mii_2)
HYF: DTO96_100888(galD)
BHO: D560_0871
BHM: D558_0857
BHZ: ACR54_03617(galD)
AFQ: AFA_05545
PNA: Pnap_2033
DAC: Daci_4451
LIM: L103DPR2_01491(galD_2)
AZO: azo2544(fldA)
AOA: dqs_2701
TCL: Tchl_1057
AMIH: CO731_01870(galD)
SME: SMc00497
SMX: SM11_chr1630(fldA)
SMER: DU99_09680
ARA: Arad_2914
RLE: RL2850
RPA: RPA4696(FldA)
RPB: RPB_0878
RPD: RPD_0988
RPE: RPE_0745
RPT: Rpal_5177
PHL: KKY_3765
MALG: MALG_02282
LABT: FIU93_13990(galD)
ROT: FIV09_09365(galD)
MALU: KU6B_25080(fldA) KU6B_53780
NAR: Saro_2818
SMAZ: LH19_17720
SPHI: TS85_18490
SSAN: NX02_17530
SSY: SLG_12560
SPHR: BSY17_3452
SFLA: SPHFLASMR4Y_02982(galD)
BLAS: BSY18_3518
AAY: WYH_01903(galD)
ADO: A6F68_01085(galD)
ALB: AEB_P0248
MAG: amb0250
MAGX: XM1_1086
MAGN: WV31_13590
MAGQ: MGMAQ_2664
MSHG: MSG_02375
SALB: XNR_3396
SFA: Sfla_3395
STRP: F750_3341(prpF)
SLE: sle_08620(sle_08620)
STRD: NI25_00245
SMAL: SMALA_0372
SGE: DWG14_01306(galD)
MLV: CVS47_03113(galD)
AMIN: AUMI_19420
AUW: AURUGA1_00416(galD)
ACH: Achl_3362
MMAR: MODMU_2828
PSEE: FRP1_23145
ACTN: L083_3806
SLI: Slin_4025
 » show all
Reference
1  [PMID:21219457]
  Authors
Nogales J, Canales A, Jimenez-Barbero J, Serra B, Pingarron JM, Garcia JL, Diaz E
  Title
Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida.
  Journal
Mol Microbiol 79:359-74 (2011)
DOI:10.1111/j.1365-2958.2010.07448.x
  Sequence
[ppu:PP_2513]
Other DBs
ExplorEnz - The Enzyme Database: 5.3.2.8
IUBMB Enzyme Nomenclature: 5.3.2.8
ExPASy - ENZYME nomenclature database: 5.3.2.8
BRENDA, the Enzyme Database: 5.3.2.8

KEGG   REACTION: R07839
Entry
R07839                      Reaction                               

Name
4-oxalomesaconate keto---enol-isomerase
Definition
(1E)-4-Oxobut-1-ene-1,2,4-tricarboxylate <=> (1E,3E)-4-Hydroxybuta-1,3-diene-1,2,4-tricarboxylate
Equation
Reaction class
RC02426  C04324_C04434
Enzyme
Pathway
rn00362  Benzoate degradation
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K16514  4-oxalomesaconate tautomerase [EC:5.3.2.8]
Other DBs
RHEA: 28934

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