KEGG ORTHOLOGY: K16686

ORTHOLOGY: K16686

Entry

K16686                      KO

Symbol

SAV1, Sav

Name

scaffold protein salvador

Pathway

map04214

Apoptosis - fly

map04390

Hippo signaling pathway

map04391

Hippo signaling pathway - fly

map04392

Hippo signaling pathway - multiple species

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    K16686  SAV1, Sav; scaffold protein salvador
   04391 Hippo signaling pathway - fly
    K16686  SAV1, Sav; scaffold protein salvador
   04392 Hippo signaling pathway - multiple species
    K16686  SAV1, Sav; scaffold protein salvador
09140 Cellular Processes
  09143 Cell growth and death
   04214 Apoptosis - fly
    K16686  SAV1, Sav; scaffold protein salvador

Genes

HSA:	60485(SAV1)

PTR:	100609966 129143853 452899(SAV1) 738861(GYPE)

PPS:	100977676(SAV1) 117974336

GGO:	101140719(SAV1)

PON:	100435936(SAV1)

PPYG:

129012198(SAV1)

NLE:	100603888(SAV1)

HMH:	116484467(SAV1)

SSYN:

129487919(SAV1)

MCC:	706424(SAV1)

MCF:	101925164(SAV1)

MTHB:

126958522

MNI:	105481837(SAV1)

CSAB:

103228963(SAV1)

CATY:

105586604(SAV1)

PANU:

101006986(SAV1)

TGE:	112628293(SAV1)

MLEU:

105553621(SAV1)

RRO:	104682745(SAV1)

RBB:	108513649(SAV1)

TFN:	117069664(SAV1)

PTEH:

111549433(SAV1)

CANG:

105522387(SAV1)

CJC:	100415144(SAV1)

SBQ:	101046327(SAV1)

CIMI:

108287989(SAV1)

ANAN:

105719927(SAV1)

CSYR:

103276414(SAV1)

MMUR:

105867638(SAV1)

LCAT:

123649388(SAV1)

PCOQ:

105825913(SAV1)

OGA:	100940724(SAV1)

MMU:	64010(Sav1)

MCAL:

110306679(Sav1)

MPAH:

110324307(Sav1)

RNO:	299116(Sav1)

MCOC:

116079830(Sav1)

ANU:	117716900(Sav1)

MUN:	110558843(Sav1)

CGE:	100766170(Sav1)

MAUA:

101838854(Sav1)

PROB:

127230655(Sav1)

PLEU:

114684143(Sav1)

MORG:

121452387(Sav1)

MFOT:

126508344

AAMP:

119819101(Sav1)

NGI:	103731507(Sav1)

HGL:	101726669(Sav1)

CPOC:

100728249(Sav1)

CCAN:

109687220(Sav1)

DORD:

105982680(Sav1)

DSP:	122106491(Sav1)

PLOP:

125363425(Sav1)

NCAR:

124976184

MMMA:

107146708(Sav1)

OCU:

100350937

OPI:	101526725(SAV1)

TUP:	102482180(SAV1)

GVR:	103582510 103589428(SAV1)

CFA:	480319(SAV1)

CLUD:

112657035(SAV1)

VVP:	112921446(SAV1)

VLG:	121492966(SAV1)

NPO:	129496260(SAV1)

AML:	100471944(SAV1)

UMR:	103665306(SAV1)

UAH:	113266215(SAV1)

UAR:	123793249(SAV1)

ELK:

111161298

LLV:

125103696

MPUF:

101679498(SAV1)

MNP:	131999933(SAV1)

MLK:	131836544(SAV1)

NVS:	122893056(SAV1)

ORO:	101362553(SAV1)

EJU:	114207503(SAV1)

ZCA:	113910321(SAV1)

MLX:	118002158(SAV1)

NSU:	110590525(SAV1)

LWW:	102737859(SAV1)

FCA:	101096154(SAV1)

PYU:	121031749(SAV1)

PCOO:

112855762(SAV1)

PBG:	122469075(SAV1)

PVIV:

125167518(SAV1)

LRUF:

124512203

PTG:	102962029(SAV1)

PPAD:

109268498(SAV1)

PUC:

125909515

AJU:

106981944

HHV:	120220275(SAV1)

BTA:	516557(SAV1)

BOM:	102268056(SAV1)

BIU:	109565023(SAV1)

BBUB:

102414280(SAV1)

BBIS:

104990278(SAV1)

CHX:	102185923(SAV1)

OAS:	101104666(SAV1)

BTAX:

128054436(SAV1)

ODA:	120853119(SAV1)

CCAD:

122443471(SAV1)

MBEZ:

129563209(SAV1)

SSC:	100156165(SAV1)

CFR:	102515400(SAV1)

CBAI:

105078431(SAV1)

CDK:	105091411(SAV1)

VPC:	102539630(SAV1)

BACU:

102998764(SAV1)

BMUS:

118889696(SAV1)

LVE:	103072979(SAV1)

OOR:	101287217(SAV1)

DLE:	111173172(SAV1)

PCAD:

102981231(SAV1)

PSIU:

116748403(SAV1)

NASI:

112392193(SAV1)

ECB:	100066557(SAV1)

EPZ:	103559181(SAV1)

EAI:	106839502(SAV1)

MYB:	102263616(SAV1)

MYD:	102766579(SAV1)

MMYO:

118655050(SAV1)

MLF:	102434744(SAV1)

MDT:	132234937(SAV1)

PKL:	118718404(SAV1)

EFUS:

103283754(SAV1)

MNA:	107525860(SAV1)

DRO:	112311358(SAV1)

SHON:

118992382(SAV1)

AJM:	119057051(SAV1)

PDIC:

114492586(SAV1)

PHAS:

123808195(SAV1)

MMF:	118632634(SAV1)

PPAM:

129066044(SAV1)

HAI:	109375232(SAV1)

RFQ:	117023936(SAV1)

PALE:

102888026(SAV1)

PGIG:

120604447(SAV1)

PVP:	105310250(SAV1)

RAY:	107511444(SAV1)

MJV:	108402320(SAV1)

TOD:	119239078(SAV1)

SARA:

101557212(SAV1)

SETR:

125999342(SAV1)

LAV:	100674511(SAV1)

TMU:

101349256

ETF:	101648114(SAV1)

DNM:	101422072(SAV1)

MDO:	100010219(SAV1)

GAS:	123237676(SAV1)

SHR:	100913559(SAV1)

AFZ:

127549750

PCW:	110220598(SAV1)

TVP:	118830081(SAV1)

OAA:	100084738(SAV1)

GGA:	423578(SAV1)

PCOC:

116234592(SAV1)

MGP:	100541762(SAV1)

CJO:	107315504(SAV1)

TPAI:

128087224(SAV1)

LMUT:

125695099(SAV1)

NMEL:

110401963(SAV1)

APLA:

101803691(SAV1)

ACYG:

106049311(SAV1)

CATA:

118250223(SAV1)

AFUL:

116489654(SAV1)

TGU:	100228633(SAV1)

LSR:	110474779(SAV1)

SCAN:

103826308(SAV1)

PMOA:

120497055(SAV1)

OTC:	121338697(SAV1)

PRUF:

121348677(SAV1)

GFR:	102031872(SAV1)

FAB:	101819168(SAV1)

OMA:	130253493(SAV1)

PHI:	102113270(SAV1)

PMAJ:

107205882(SAV1)

CCAE:

111929643(SAV1)

CCW:	104695894(SAV1)

CBRC:

103618856(SAV1)

ETL:	114070144(SAV1)

ZLE:	135449211(SAV1)

ACHL:

103800813(SAV1)

SVG:	106858948(SAV1)

MMEA:

130584189(SAV1)

HRT:	120753616(SAV1)

SATI:

136362721(SAV1)

FPG:	101912368(SAV1)

FCH:	102057287(SAV1)

CCRI:

104160397(SAV1)

NNT:	104411697(SAV1)

SHAB:

115607507(SAV1)

ACUN:

113480816(SAV1)

TALA:

104362872(SAV1)

ACHC:

115350435(SAV1)

HALD:

104311994(SAV1)

HLE:	104839467(SAV1)

AGEN:

126050735

GCL:

127017324

CSTI:

104553935(SAV1)

LDI:	104346682(SAV1)

MNB:	103771528(SAV1)

DPUB:

104299350(SAV1)

AVIT:

104271069(SAV1)

BRHI:

104499422(SAV1)

EGZ:	104135023(SAV1)

NNI:	104019451(SAV1)

PCRI:

104024833(SAV1)

PCAO:

104047002(SAV1)

PADL:

103915991(SAV1)

AFOR:

103907639(SAV1)

FGA:	104074310(SAV1)

GSTE:

104257078(SAV1)

CLV:	102088007(SAV1)

MUI:	104537448(SAV1)

PGUU:

104467792(SAV1)

PLET:

104614391(SAV1)

EHS:	104513516(SAV1)

CMAC:

104477011(SAV1)

CUCA:

104057416(SAV1)

TEO:	104370191(SAV1)

BREG:

104643852(SAV1)

OHA:	104327775(SAV1)

ACAR:

104531252(SAV1)

CPEA:

104394476(SAV1)

CVF:	104294300(SAV1)

RTD:	128908239(SAV1)

AAM:	106491617(SAV1)

AROW:

112961225(SAV1)

NPD:	112957792(SAV1)

TGT:	104576530(SAV1)

DNE:	112993931(SAV1)

SCAM:

104145365(SAV1)

ASN:	102387931(SAV1)

AMJ:	102567340(SAV1)

CPOO:

109320709(SAV1)

GGN:	109298324(SAV1)

PSS:	102456522(SAV1)

CMY:	102947771(SAV1)

CCAY:

125637737(SAV1)

DCC:	119857920(SAV1)

CPIC:

101931382(SAV1)

TST:	117876643(SAV1)

CABI:

116822060(SAV1)

MRV:	120405442(SAV1)

ACS:

100557264

ASAO:

132760754(SAV1)

PVT:	110089149(SAV1)

SUND:

121919447(SAV1)

PBI:	103065265(SAV1)

PMUR:

107293427(SAV1)

CTIG:

120301827(SAV1)

TSR:	106546793(SAV1)

PGUT:

117675053(SAV1)

APRI:

131188102(SAV1)

PTEX:

113435142(SAV1)

NSS:	113414127(SAV1)

VKO:	123026750(SAV1)

PMUA:

114592822(SAV1)

PRAF:

128413635(SAV1)

ZVI:	118075954(SAV1)

HCG:	128339906(SAV1)

GJA:	107122510(SAV1)

STOW:

125427111

EMC:	129324550(SAV1)

XLA:	108699791(sav1.S) 447543(sav1.L)

XTR:	448321(sav1)

NPR:	108788590(SAV1)

RTEM:

120920230(SAV1)

BBUF:

120982568(SAV1)

BGAR:

122921479(SAV1)

MUO:	115477265(SAV1)

GSH:	117363730(SAV1)

DRE:	447821(sav1)

SRX:	107705447 107736858

SANH:

107654943 107682971

SGH:	107553191 107602930 107602931

CCAR:

109059128 109059146(sav1)

CAUA:

113056801(sav1)

CGIB:

127970525 128026011

PTET:

122356987(sav1)

LROH:

127175554(sav1)

OMC:	131552782(sav1)

PPRM:

120467864(sav1)

RKG:	130088243(sav1)

MAMB:

125277311(sav1)

CIDE:

127525064

CERY:

137020173(sav1)

MASI:

127411657 127414217

TROS:

130559231(sav1)

TDW:	130431305(sav1)

MANU:

129416228(sav1)

IPU:

108263513

IFU:	128605844(sav1)

PHYP:

113537880(sav1)

SMEO:

124400558(sav1)

TFD:	113661035(sav1)

TVC:	132847442(sav1)

TRN:	134314848(sav1)

AMEX:

103025171(sav1)

CMAO:

118810662(sav1)

EEE:	113583457(sav1)

CHAR:

105891001(sav1)

TRU:	101080105(sav1)

TFS:	130539902(sav1)

TNG:	GSTEN00035784G001

LCO:	104937954(sav1)

NCC:	104954139(sav1)

TBEN:

117481371(sav1)

PGEO:

117467291(sav1)

GACU:

117558003(sav1)

EMAC:

134881017(sav1)

ELY:	117267657(sav1)

EFO:	125901243(sav1)

PLEP:

121953944(sav1)

SLUC:

116057423(sav1)

ECRA:

117935422(sav1)

ESP:	116669720(sav1)

PFLV:

114546506(sav1)

GAT:	120833356(sav1)

PPUG:

119227442(sav1)

AFB:	129103176(sav1)

CLUM:

117725286(sav1)

PSWI:

130201083(sav1)

MSAM:

119910241(sav1)

SCHU:

122861411(sav1)

CUD:	121526301(sav1)

ALAT:

119004558(sav1)

MZE:	101473946(sav1)

ONL:	100702084(sav1)

OAU:	116318085(sav1)

OLA:	101159545(sav1)

OML:	112148441(sav1)

CSAI:

133462083(sav1)

XMA:	102234511(sav1)

XCO:	114134414(sav1)

XHE:	116709295(sav1)

PRET:

103458318(sav1)

PFOR:

103144727(sav1)

PLAI:

106946978(sav1)

PMEI:

106922071(sav1)

GAF:	122845945(sav1)

PPRL:

129365085(sav1)

CVG:	107097182(sav1)

CTUL:

119783571(sav1)

GMU:	124855371(sav1)

NFU:	107391753(sav1)

KMR:	108237562(sav1)

ALIM:

106511144(sav1) 106517965

NWH:	119427057(sav1)

AOCE:

111584585(sav1)

MCEP:

125023565(sav1)

CSEM:

103380859(sav1)

POV:	109636313(sav1)

SSEN:

122782869(sav1)

HHIP:

117756673(sav1)

HSP:	118116566(sav1)

PPLT:

128450610(sav1)

SMAU:

118285750(sav1)

LCF:

108886703

SDU:	111225491(sav1)

SLAL:

111665868(sav1)

XGL:	120795684(sav1)

HCQ:	109517408(sav1)

SSCV:

125981039

SBIA:

133513099(sav1)

PEE:	133412773(sav1)

PTAO:

133488348(sav1)

BPEC:

110167122(sav1)

MALB:

109973396(sav1)

BSPL:

114848670(sav1)

SJO:	128375055(sav1)

SASA:

106601755(sav1) 106611457

STRU:

115161903 115172976(sav1)

OTW:	112247872 112262358(sav1)

OMY:	110498279(sav1) 110505959

OGO:	124001328(sav1) 124046781

ONE:	115115181 115146492(sav1)

OKI:	109881837(sav1) 109904627

OKE:	118362011(sav1) 118373684

SALP:

112069981 112072061

SNH:	120023781 120060123(sav1)

CCLU:

121539102(sav1) 121544580

ELS:	114828668 114840934

SFM:	108919459(sav1)

PKI:	111842709(sav1)

AANG:

118221424(sav1)

LOC:	102682168(sav1)

PSPA:

121324159(sav1) 121329826

ARUT:

117415748 117421978

PSEX:

120518340(sav1)

LCM:	102366607(SAV1)

CMK:	103175267(sav1)

RTP:	109914932(sav1)

CPLA:

122553589(sav1)

HOC:	132817918(sav1)

LERI:

129700528(sav1)

PMRN:

116939706 116953995(SAV1)

LRJ:	133347358 133356302(SAV1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

SKO:

DME:	Dmel_CG33193(sav)

DER:

6554754

DSI:	Dsimw501_GD18409(Dsim_GD18409)

DYA:	Dyak_GE23988

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI10759

DAZ:

DNV:

DHE:

CCAT:

BOD:

RZE:

AOQ:

TDA:	119665367 119685369 119685370

MDE:

101893152

SCAC:

106082437

LCQ:

111681613

LSQ:	119613942 119614943

GFS:

ECOE:

CLON:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ006349

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

AROA:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_202281

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM105930

FOC:

TPAL:

ZNE:

CSEC:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_16039

DMK:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

CEL:	CELE_T10H10.3(sav-1)

CBR:	CBG_02143(Cbr-sav-1)

CRQ:	GCK72_023932

BMY:	BM_BM5724(Bma-sav-1)

LOA:	LOAG_06931

TSP:

Tsp_07055

LGI:	LOTGIDRAFT_189497

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

MYI:

PMAX:

MMER:

OBI:

OSN:

LAK:	106176293 106178708

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

MBR:	MONBRDRAFT_23221

SRE:	PTSG_01509

» show all

Reference

PMID:11027580

Authors

Valverde P

Title

Cloning, expression, and mapping of hWW45, a novel human WW domain-containing gene.

Journal

Biochem Biophys Res Commun 276:990-8 (2000)
DOI:10.1006/bbrc.2000.3582

Sequence

[hsa:60485]

Reference

PMID:21104395

Authors

Park Y, Park J, Lee Y, Lim W, Oh BC, Shin C, Kim W, Lee Y

Title

Mammalian MST2 kinase and human Salvador activate and reduce estrogen receptor alpha in the absence of ligand.

Journal

J Mol Med (Berl) 89:181-91 (2011)
DOI:10.1007/s00109-010-0698-y

Sequence

[hsa:60485]

All links

Ontology (1)   
   KEGG BRITE (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Gene (1508)   
   KEGG GENES (658)   
   KEGG MGENES (180)   
   RefGene (667)   
   OC (3)   
Literature (2)   
   PubMed (2)   
All databases (1519)   

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