KEGG ORTHOLOGY: K17501

ORTHOLOGY: K17501

Entry

K17501                      KO

Symbol

PPM1E, POPX1

Name

protein phosphatase 1E [EC:3.1.3.16]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K17501  PPM1E, POPX1; protein phosphatase 1E
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K17501  PPM1E, POPX1; protein phosphatase 1E
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Mg2+- or Mn2+- dependent protein phosphatases (PPMs)
   PPM1 phosphatases (PP2C)
    K17501  PPM1E, POPX1; protein phosphatase 1E

Other DBs

GO:

0004722

Genes

HSA:	22843(PPM1E)

PTR:	468424(PPM1E)

PPS:	100982096(PPM1E)

GGO:	101131331(PPM1E)

PON:	100436149(PPM1E)

PPYG:

129017391(PPM1E)

NLE:	100583415(PPM1E)

HMH:	116474409(PPM1E)

SSYN:

129470602(PPM1E)

MCC:	711012(PPM1E)

MCF:	102121318(PPM1E)

MTHB:

126939377

MNI:	105476835(PPM1E)

CSAB:

103242833(PPM1E)

CATY:

105583325(PPM1E)

PANU:

101021942 116270981

TGE:	112609746(PPM1E)

MLEU:

105539131(PPM1E)

RRO:	104672962(PPM1E)

RBB:	108521633(PPM1E)

TFN:	117067311(PPM1E)

PTEH:

111537641(PPM1E)

CANG:

105520159(PPM1E)

CJC:	100384967(PPM1E)

SBQ:	101028066(PPM1E)

CIMI:

108312029(PPM1E)

ANAN:

105712450(PPM1E)

CSYR:

103270764(PPM1E)

MMUR:

105873099(PPM1E)

LCAT:

123620417(PPM1E)

PCOQ:

105813683(PPM1E)

OGA:	100941274(PPM1E)

MMU:	320472(Ppm1e)

MCAL:

110304698(Ppm1e)

MPAH:

110331514(Ppm1e)

RNO:	360593(Ppm1e)

MCOC:

116077432(Ppm1e)

ANU:	117710770(Ppm1e)

ASYL:

127695474(Ppm1e)

MUN:	110566275(Ppm1e)

CGE:	113836769(Ppm1e)

MAUA:

101843606(Ppm1e)

PROB:

127225441(Ppm1e)

PLEU:

114699271(Ppm1e)

MORG:

121456402(Ppm1e)

MFOT:

126486979

AAMP:

119813509(Ppm1e)

NGI:	103741773(Ppm1e)

HGL:	101717082(Ppm1e)

CPOC:

100727584(Ppm1e)

CCAN:

109678928 109686749(Ppm1e)

DORD:

105983411(Ppm1e)

DSP:	122117164(Ppm1e)

DMER:

138830602(Ppm1e)

PLOP:

125366424(Ppm1e)

NCAR:

124978908

MMMA:

107150394(Ppm1e)

ITI:	101960554(Ppm1e)

OCU:

103351534

OPI:	101531983(PPM1E)

TUP:	102499786(PPM1E)

CFA:	612897(PPM1E)

CLUD:

112655671(PPM1E)

VVP:	112917928(PPM1E)

VLG:	121472824(PPM1E)

NPO:	129504595(PPM1E)

AML:	100467854(PPM1E)

UMR:	103667458(PPM1E)

UAR:	123777084(PPM1E)

ELK:

111151723

LLV:

125088034

MPUF:

101683834(PPM1E)

MNP:	132004295(PPM1E)

MLK:	131816510(PPM1E)

NVS:	122906521(PPM1E)

ORO:	101383848(PPM1E)

EJU:	114213833(PPM1E)

ZCA:	113908009(PPM1E)

MLX:	118024697(PPM1E)

NSU:	110593088(PPM1E)

LWW:	102745966(PPM1E)

FCA:	101081844(PPM1E)

PYU:	121044709(PPM1E)

PCOO:

112855495(PPM1E)

PBG:	122485314(PPM1E)

PVIV:

125151426(PPM1E)

LRUF:

124513183

LGF:	123603380(PPM1E)

AJU:

106989972

PTG:	102950791(PPM1E)

PPAD:

109256086(PPM1E)

PUC:

125927427

PLEZ:

122206265(PPM1E)

HHV:	120241911(PPM1E)

BTA:	532050(PPM1E)

BOM:	102269843(PPM1E)

BIU:	109573165(PPM1E)

BBUB:

102415057(PPM1E)

BBIS:

105004190(PPM1E)

CHX:	102189429(PPM1E)

OAS:	101106345(PPM1E)

BTAX:

128065374(PPM1E)

CSUM:

138084641(PPM1E)

ODA:	120866453(PPM1E)

CCAD:

122450504(PPM1E)

MREE:

136149207(PPM1E)

OVR:	110142199(PPM1E)

MBEZ:

129539248(PPM1E)

SSC:	100518751(PPM1E)

CFR:	102512524(PPM1E)

CBAI:

105065860(PPM1E)

CDK:	105097815(PPM1E)

VPC:	102542781(PPM1E)

BACU:

103018635(PPM1E)

BMUS:

118886543(PPM1E)

LVE:	103086314(PPM1E)

OOR:	101286801(PPM1E)

LALB:

132511129(PPM1E)

GMF:	115866342(PPM1E)

DDP:	132414618(PPM1E)

DLE:	111163748(PPM1E)

PCAD:

102984137(PPM1E)

PSIU:

116746255(PPM1E)

PPHC:

136138613(PPM1E)

NASI:

112408103(PPM1E)

ECB:	100057075(PPM1E)

EPZ:	103561739(PPM1E)

EAI:	106821848(PPM1E)

MYB:	102246888(PPM1E)

MYD:	102755897(PPM1E)

MMYO:

118671711(PPM1E)

MLF:	102441135(PPM1E)

MDT:	132218425(PPM1E)

MYUM:

138994964(PPM1E)

PKL:	118728071(PPM1E)

EFUS:

103291641(PPM1E)

MNA:	107535290(PPM1E)

DRO:	112316501(PPM1E)

SHON:

119003654(PPM1E)

AJM:	119062568(PPM1E)

PDIC:

114503223(PPM1E)

PHAS:

123817662(PPM1E)

MMF:	118633719(PPM1E)

PPAM:

129080185(PPM1E)

HAI:	109379791(PPM1E)

RFQ:	117014095(PPM1E)

PALE:

102891817(PPM1E)

PGIG:

120620812(PPM1E)

PVP:	105302116(PPM1E)

RAY:	107499156(PPM1E)

MJV:	108408405(PPM1E)

TOD:	119231686(PPM1E)

SARA:

101558061(PPM1E)

SFUM:

130035698(PPM1E)

SETR:

125995328(PPM1E)

LAV:	100658128(PPM1E)

TMU:

101358757

ETF:	101658998(PPM1E)

DNM:	101424994(PPM1E)

MDO:	100011441(PPM1E)

GAS:	123246123(PPM1E)

SHR:	100916207(PPM1E)

AFZ:

127559974

PCW:	110212062(PPM1E)

TVP:	118846533(PPM1E)

PBRV:

138153683(PPM1E)

MLAO:

141513608(PPM1E)

OAA:	100078323(PPM1E)

TACU:

119939710(PPM1E)

GGA:	417627(PPM1E)

PCOC:

116227857(PPM1E)

MGP:	100549948(PPM1E)

CJO:	107322516(PPM1E)

TPAI:

128083698(PPM1E)

LMUT:

125703112(PPM1E)

NMEL:

110407929(PPM1E)

APLA:

101795706(PPM1E)

ACYG:

106045803(PPM1E)

CATA:

118255020(PPM1E)

AFUL:

116497432(PPM1E)

TGU:	100226196(PPM1E)

LSR:	110467664(PPM1E)

SCAN:

103820333(PPM1E)

PMOA:

120507598(PPM1E)

OTC:	121347007(PPM1E)

PRUF:

121361595(PPM1E)

ATRC:

139600020(PPM1E)

GFR:	102034465(PPM1E)

FAB:	101814491(PPM1E)

OMA:	130261066(PPM1E)

PHI:	102106875(PPM1E)

PMAJ:

107212690(PPM1E)

CCAE:

111937825(PPM1E)

CCW:	104691167(PPM1E)

CBRC:

103613397(PPM1E)

ACOE:

138120485(PPM1E)

ETL:	114067729(PPM1E)

ZAB:	102065010(PPM1E)

ZLE:	135455917(PPM1E)

ACHL:

103812046(PPM1E)

SVG:	106853280(PPM1E)

MMEA:

130585518(PPM1E)

HRT:	120761208(PPM1E)

SATI:

136370185(PPM1E)

CCIC:

134052552(PPM1E)

FPG:	101917911(PPM1E)

FCH:	102052490(PPM1E)

CCRI:

104158745(PPM1E)

NNT:	104405871(PPM1E)

SHAB:

115602130(PPM1E)

ACUN:

113487056(PPM1E)

TALA:

104365094(PPM1E)

ACHC:

115346913(PPM1E)

HALD:

104321113(PPM1E)

HLE:	104835786(PPM1E)

AGEN:

126039121

HHAR:

128149589(PPM1E)

GCL:

127024398

CSTI:

104558298(PPM1E)

LDI:	104344011(PPM1E)

MNB:	103772579(PPM1E)

DPUB:

104302794(PPM1E)

PPUS:

135187649(PPM1E)

AVIT:

104277682(PPM1E)

BRHI:

104502253(PPM1E)

EGZ:	104121841(PPM1E)

NNI:	104017089(PPM1E)

PCRI:

104029562(PPM1E)

PCAO:

104045414(PPM1E)

PADL:

103917129(PPM1E)

AFOR:

103898135(PPM1E)

FGA:	104079381(PPM1E)

GSTE:

104254781(PPM1E)

CBOY:

140660975(PPM1E)

CLV:	102096031(PPM1E)

CNIC:

135995816(PPM1E)

MUI:	104548341(PPM1E)

PGUU:

104462951(PPM1E)

PLET:

104621303(PPM1E)

EHS:	104511036(PPM1E)

CMAC:

104484511(PPM1E)

CUCA:

104057199(PPM1E)

TEO:	104384166(PPM1E)

BREG:

104630122(PPM1E)

OHA:	104339657(PPM1E)

ACAR:

104527621(PPM1E)

CPEA:

104398961(PPM1E)

CVF:	104284394(PPM1E)

RTD:	128912323(PPM1E)

CRID:

134519026(PPM1E)

AAM:	106500321(PPM1E)

AROW:

112968812(PPM1E)

NPD:	112954616(PPM1E)

TGT:	104570503(PPM1E)

DNE:	112983946(PPM1E)

SCAM:

104142825(PPM1E)

ASN:	102381605(PPM1E)

AMJ:	102572168(PPM1E)

CPOO:

109317183(PPM1E)

GGN:	109293302(PPM1E)

PSS:	102455531(PPM1E)

CMY:	102932052(PPM1E)

CCAY:

125623754(PPM1E)

DCC:	119844547(PPM1E)

CPIC:

101945855(PPM1E)

TST:	117867359(PPM1E)

CABI:

116827422(PPM1E)

MRV:	120387509(PPM1E)

ACS:	100553475(ppm1e)

ASAO:

132763832(PPM1E)

PVT:	110075535(PPM1E)

SUND:

121916926(PPM1E)

PBI:	103062830(PPM1E)

PMUR:

107295179(PPM1E)

CTIG:

120319569(PPM1E)

TSR:

106544008

PGUT:

117656197(PPM1E)

PCAE:

139308461(PPM1E)

APRI:

131188660(PPM1E)

PTEX:

113442539(PPM1E)

NSS:	113424679(PPM1E)

VKO:	123023404(PPM1E)

PMUA:

114585257(PPM1E)

PRAF:

128402618(PPM1E)

ZVI:	118097147(PPM1E)

HCG:	128336020(PPM1E)

GJA:	107121282(PPM1E)

STOW:

125445816(PPM1E)

EMC:	129344837(PPM1E)

XLA:	108708316(ppm1e.L) 108709631(ppm1e.S)

XTR:	100496571(ppm1e)

NPR:	108791269(PPM1E)

RTEM:

120926684(PPM1E)

ACAT:

141128091(PPM1E)

BBUF:

120995502(PPM1E)

BGAR:

122931246(PPM1E)

DTC:	141088320(PPM1E)

PWL:	138285895(PPM1E)

MUO:	115456821(PPM1E)

GSH:	117349394(PPM1E)

DRE:	553417(ppm1e)

SRX:	107728886 107734442

SANH:

107686131 107691656

SGH:	107577402 107588822

CCAR:

109072265(ppm1e) 109072273

CAUA:

113054410 113109925

CGIB:

127966357 128021086

PTET:

122352866(ppm1e)

LROH:

127171903(ppm1e)

GRF:

141299355

OMC:	131548311(ppm1e)

PPRM:

120481751(ppm1e)

RKG:	130105483(ppm1e)

MAMB:

125262206(ppm1e)

CIDE:

127520085

CERY:

137029606(ppm1e)

MASI:

127432903 127433997

TROS:

130546089(ppm1e)

TDW:	130412159(ppm1e)

MANU:

129446827(ppm1e)

PDAB:

135741121(ppm1e)

IPU:

108277257

IFU:	128620473(ppm1e)

PHYP:

113524170

SMEO:

124393740(ppm1e)

TFD:	113650270(ppm1e)

TVC:	132863614(ppm1e)

CGAR:

128505661(ppm1e)

NGRA:

132873517(ppm1e)

TRN:	134332635(ppm1e)

AMEX:

103042334(ppm1e)

CMAO:

118824733(ppm1e)

EEE:

113568249

CHAR:

105909783(ppm1e)

SPIL:

134080652(ppm1e)

TRU:	101071285(ppm1e)

TFS:	130537502(ppm1e)

TNG:	GSTEN00014651G001

LCO:	104918960(ppm1e)

NCC:

104944643

TBEN:

117490741(ppm1e)

PGEO:

117458039(ppm1e)

GACU:

117548933(ppm1e)

EMAC:

134872641(ppm1e)

ELY:	117268403(ppm1e)

EFO:	125898515(ppm1e)

PLEP:

121952107(ppm1e)

SLUC:

116055973(ppm1e)

ECRA:

117955768(ppm1e)

ESP:	116701106(ppm1e)

PFLV:

114567392(ppm1e)

GAT:	120821637(ppm1e)

PPUG:

119215086(ppm1e)

AFB:	129113844(ppm1e)

CLUM:

117742712(ppm1e)

PSWI:

130191897(ppm1e)

CANA:

137802627(ppm1e)

CVE:	137890772(ppm1e)

MSAM:

119895850(ppm1e)

SCHU:

122887957(ppm1e)

CUD:	121518459(ppm1e)

SPUL:

138599239(ppm1e)

LMIX:

132988848(ppm1e)

ALAT:

119031715(ppm1e)

ASTR:

137605925(ppm1e)

MZE:	101482463(ppm1e)

ONL:	100694623(ppm1e)

OAU:	116319051(ppm1e)

OLA:	101162311(ppm1e)

OML:	112143025(ppm1e)

CSAI:

133459377(ppm1e)

XMA:	102227305(ppm1e)

XCO:	114152854(ppm1e)

XHE:	116716552 116716554 116716556 116728854

PRET:

103460014(ppm1e)

PFOR:

103131793(ppm1e)

PLAI:

106938915(ppm1e)

PMEI:

106904460(ppm1e)

GAF:	122844771(ppm1e)

PPRL:

129356311

CVG:	107098403(ppm1e)

GMU:	124876364(ppm1e)

NFU:	107386630(ppm1e)

KMR:	108238060(ppm1e)

ALIM:

106530607(ppm1e)

NWH:	119420829(ppm1e)

AOCE:

111568604(ppm1e)

EJA:	138196074(ppm1e)

BFRE:

138627419(ppm1e)

MCEP:

125020841(ppm1e)

CSEM:

103395069(ppm1e)

POV:	109628510(ppm1e)

SSEN:

122779961(ppm1e)

SSOE:

131457965(ppm1e)

HHIP:

117774207(ppm1e)

HSP:	118122496(ppm1e)

PPLT:

128457598(ppm1e)

SMAU:

118300387(ppm1e)

LCF:

108893666

SDU:	111234528(ppm1e)

SLAL:

111659967(ppm1e)

XGL:	120802286(ppm1e)

HCQ:	109517654(ppm1e)

SSCV:

125981890

SBIA:

133491749

PEE:	133415557(ppm1e)

PTAO:

133467187(ppm1e)

BPEC:

110166322(ppm1e)

ENY:	140361247(ppm1e)

MALB:

109959307(ppm1e)

BSPL:

114869094(ppm1e)

SJO:	128371807(ppm1e)

SSCO:

133993535(ppm1e)

GMH:	115546943(ppm1e)

SASA:

106567667 106603465(ppm1e)

STRU:

115148792 115154262

OTW:	112229106 112257925

OMY:	110533585(ppm1e) 110537546

OGO:	124000397 124011202

ONE:	115105480 115135963(ppm1e)

OKI:	109873095(ppm1e) 109892797

OKE:	118390033 118391103

OMM:	135548664 135550748

OCLA:

139418202 139423161

SALP:

111951193(ppm1e) 111981914

SNH:	120044338 120057446

CCLU:

121550459 121579387

ELS:	105011105(ppm1e)

OEP:	134039329(ppm1e)

SFM:	108928234(ppm1e)

PKI:	111847876(ppm1e)

AANG:

118236019(ppm1e)

AROT:

135263891(ppm1e)

CCOG:

133133831(ppm1e)

LOC:	102696415(ppm1e)

PSPA:

121308501(ppm1e)

ARUT:

117429118

PSEX:

120531440(ppm1e)

LCM:	102353055(PPM1E)

CMK:	103186916(ppm1e)

RTP:	109916174(ppm1e)

CPLA:

122563915(ppm1e)

HOC:	132830476(ppm1e)

LERI:

129710568(ppm1e)

HAKA:

140731609(ppm1e)

PMRN:

116939077 116950118

LRJ:	133348535(PPM1F) 133348727

BFO:	118426608 118432401

BBEL:

CIN:

SCLV:

SPU:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

DME:	Dmel_CG10376(CG10376)

DER:

6549233

DSE:

6614579

DSI:	Dsimw501_GD21815(Dsim_GD21815)

DYA:	Dyak_GE12714

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI22508

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:

GFS:

CQU:	CpipJ_CPIJ010239

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

PGC:

OBO:

VPS:

NVL:

BMOR:

BMAN:

DPL:	KGM_212162 KGM_212163

PMAC:

PXU:

BPHI:

ZCE:

AAGE:

HAW:

TNL:

ONU:

ATRA:

GMW:

LGLY:

CSTB:

CFUM:

API:

DNX:

AGS:

RMD:

PHU:	Phum_PHUM320130

FCD:

PCHN:

DSV:

DPTE:

CSCU:

PTEP:

CEL:	CELE_T19C3.8(fem-2)

CBR:	CBG_15267(Cbr-fem-2)

CRQ:	GCK72_011898

LOA:	LOAG_18516

TSP:

Tsp_01554

LGI:	LOTGIDRAFT_174041

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MMER:

RPHI:

MAEA:

OBI:

OSN:

LJP:

LAK:	106153513 106154910

LLON:

NVE:

EPA:

ATEN:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:	114520432 114538262

HMG:

100214781

RES:

135683137

TAD:	TRIADDRAFT_28894

AQU:

100633385

MBR:	MONBRDRAFT_32120

SRE:	PTSG_00335

PIF:	PITG_21172

PSOJ:

PHYSODRAFT_531875

» show all

Reference

PMID:11864573

Authors

Koh CG, Tan EJ, Manser E, Lim L

Title

The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family.

Journal

Curr Biol 12:317-21 (2002)
DOI:10.1016/S0960-9822(02)00652-8

Sequence

[hsa:22843]

All links

Ontology (1)   
   GO (1)   
Gene (932)   
   MGENES (131)   
   RefGene (794)   
   OC (7)   
All databases (933)   

Download RDF

DBGET integrated database retrieval system