KEGG   ORTHOLOGY: K17709
Entry
K17709                      KO                                     
Symbol
CYP2B6
Name
cytochrome P450 family 2 subfamily B6 [EC:1.14.14.-]
Pathway
map00590  Arachidonic acid metabolism
map00830  Retinol metabolism
map00980  Metabolism of xenobiotics by cytochrome P450
map00982  Drug metabolism - cytochrome P450
map01100  Metabolic pathways
map05207  Chemical carcinogenesis - receptor activation
map05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
   00982 Drug metabolism - cytochrome P450
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.-
     K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, animal type
  CYP2 family
   K17709  CYP2B6; cytochrome P450 family 2 subfamily B6
Other DBs
RN: R07000 R07048 R07050 R07051 R07052 R08275 R08285 R08286 R08287 R08313 R08324 R08325 R08326 R08390 R08391 R08392 R09441
Genes
HSA: 1555(CYP2B6)
PTR: 104003379 456052
PPS: 100984180(CYP2B6)
GGO: 101151678
PON: 100457779 100458142
NLE: 101179527
HMH: 116480657
MCC: 114675607 678687(CYP2B6)
MCF: 102124427(CYP2B6)
MTHB: 126942029
MNI: 105495315
CSAB: 103234720
CATY: 105597999
PANU: 101001292
TGE: 112617245 112617418
MLEU: 105542145
RRO: 104676093 104676096
RBB: 108536168 108536170
TFN: 117087868
PTEH: 111554026
CANG: 105507826
CJC: 100405958(CYP2B6)
SBQ: 101041829
CIMI: 108285668(CYP2B6)
CSYR: 103268360
MMUR: 105869127 105869130 105869132
LCAT: 123624287 123624291 123624292
PCOQ: 105820597 105820600
MDO: 100018958
 » show all
Reference
PMID:2573390
  Authors
Yamano S, Nhamburo PT, Aoyama T, Meyer UA, Inaba T, Kalow W, Gelboin HV, McBride OW, Gonzalez FJ
  Title
cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver.
  Journal
Biochemistry 28:7340-8 (1989)
DOI:10.1021/bi00444a029
  Sequence
[hsa:1555]

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (14)   
   KEGG PATHWAY (14)   
Chemical reaction (33)   
   KEGG REACTION (17)   
   KEGG RCLASS (16)   
Gene (41)   
   KEGG GENES (40)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (92)   

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