KEGG   ORTHOLOGY: K17865Help
Entry
K17865                      KO                                     

Name
croR
Definition
3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
Pathway
ko00630  Glyoxylate and dicarboxylate metabolism
ko00650  Butanoate metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
ko01200  Carbon metabolism
Module
M00373  Ethylmalonyl pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    K17865  croR; 3-hydroxybutyryl-CoA dehydratase
   00650 Butanoate metabolism
    K17865  croR; 3-hydroxybutyryl-CoA dehydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.55  3-hydroxybutyryl-CoA dehydratase
     K17865  croR; 3-hydroxybutyryl-CoA dehydratase
BRITE hierarchy
Other DBs
RN: R03027
COG: COG2030
GO: 0003859
Genes
ENR: H650_03750
CIE: AN232_13780
KSA: C813_04365
KOR: AWR26_00185
KRD: A3780_24495
HPAR: AL518_12420
PSUW: WQ53_08610
LYT: DWG18_00380
VVL: VV93_v1c03360
VPK: M636_20740
ABH: M3Q_289
SSE: Ssed_3537
SHL: Shal_2740
CPS: CPS_3371
MARJ: MARI_25330(phaJ_2)
CYQ: Q91_1228 Q91_1346(maoC)
AEH: Mlg_2811
HHA: Hhal_1055
HHK: HH1059_24760(phaJ)
ADI: B5T_04119
AXE: P40_20070
CVI: CV_3819
LHK: LHK_02914
PSE: NH8B_3503
AMAH: DLM_0091
RME: Rmet_1672
BVE: AK36_5946
BAM: Bamb_6218
BCED: DM42_2061
BCON: NL30_35025
BPH: Bphy_6753
ODI: ODI_R3784
PNA: Pnap_3284
LCH: Lcho_3597
EBA: ebA4434
DSU: Dsui_1352
DAR: Daro_3467
AZO: azo3194
AZA: AZKH_1173
AOA: dqs_3327
TCL: Tchl_0770
AMYT: AMYT_0898
ARC: ABLL_0105
DAT: HRM2_42120(maoC)
BBAC: EP01_18065
MES: Meso_1940
RIR: BN877_p0414(maoC)
BJA: blr3306
XAU: Xaut_2482
AZC: AZC_0033
MEX: Mext_3444
MEA: Mex_1p3675(croR)
MDI: METDI4248(croR)
MCH: Mchl_3753
MPO: Mpop_3642
MET: M446_5194
MNO: Mnod_5970
MOR: MOC_5744
META: Y590_16915
MAQU: Maq22A_c17200(croR)
HDN: Hden_2610
RVA: Rvan_1595
BVR: BVIR_2707
BLAG: BLTE_01590
MSC: BN69_2149
PLEO: OHA_1_01877(croR)
MCG: GL4_0954
HDI: HDIA_1083(phaJ)
RBM: TEF_16395
PZU: PHZ_c3159
SIL: SPO3152
RSP: RSP_2305
JAN: Jann_3364
RDE: RD1_3522
PDE: Pden_3661
DSH: Dshi_2926
PGD: Gal_00894
OTM: OSB_06610(phaJ)
LAQU: R2C4_12595
CID: P73_3639
MALG: MALG_02943
RHC: RGUI_1403
SPSE: SULPSESMR1_02408(phaJ)
RMM: ROSMUCSMR3_00429(phaJ)
LVS: LOKVESSMR4R_00151(phaJ)
AHT: ANTHELSMS3_02031(phaJ)
HNE: HNE_0843
HBA: Hbal_0980
GAK: X907_0954
ACR: Acry_0584
SHUM: STHU_52650(phaJ)
RRU: Rru_A2964
RRF: F11_15185
RCE: RC1_3580
MAG: amb0831
MGRY: MSR1_22260(phaJ)
MAGX: XM1_4442(phaJ)
MAGN: WV31_01260
TMO: TMO_2893
TXI: TH3_16910
MAGQ: MGMAQ_0317(phaJ)
HTL: HPTL_0565
CTC: CTC_00706(maoC)
CTET: BN906_00740(maoC)
CBE: Cbei_2038
CKL: CKL_3022
CKR: CKR_2670
CPAT: CLPA_c39950(croR)
CPAE: CPAST_c39950(croR)
CSQ: CSCA_2634
CTYK: CTK_C16670
AMT: Amet_3092
AOE: Clos_1346
CCT: CC1_14800
SWO: Swol_1356
SLP: Slip_2090
TTE: TTE0551(MaoC)
APR: Apre_0115
PHAR: NCTC13077_00525(phaJ)
PUF: UFO1_3308
PFT: JBW_01154
MANA: MAMMFC1_02836(phaJ)
STED: SPTER_29440(phaJ_1) SPTER_47280(phaJ_2)
ACL: ACL_0741
ABRA: BN85306540
MBJ: KQ51_00857(phaJ)
CAG: Cagg_0370
TAQ: TO73_0932
LIE: LIF_A3279(maoC)
LIS: LIL_13379(maoC3)
BPO: BP951000_1039(maoC)
BPW: WESB_2381
BIP: Bint_2793
FNU: FN0816
SRU: SRU_0069
SRM: SRM_00070(maoC)
RMR: Rmar_2748
HSW: Hsw_0821
CPRV: CYPRO_0733
TAF: THA_425
THER: Y592_02105
PMO: Pmob_1081
MARN: LN42_02770
KOL: Kole_0962
GAH: GAH_01713
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Reiser SE, Mitsky TA, Gruys KJ
  Title
Characterization and cloning of an (R)-specific trans-2,3-enoylacyl-CoA hydratase from Rhodospirillum rubrum and use of this enzyme for PHA production in Escherichia coli.
  Journal
Appl Microbiol Biotechnol 53:209-18 (2000)
DOI:10.1007/s002530050010
Reference
  Authors
Korotkova N, Chistoserdova L, Kuksa V, Lidstrom ME
  Title
Glyoxylate regeneration pathway in the methylotroph Methylobacterium extorquens AM1.
  Journal
J Bacteriol 184:1750-8 (2002)
DOI:10.1128/JB.184.6.1750-1758.2002
  Sequence

KEGG   ENZYME: 4.2.1.55Help
Entry
EC 4.2.1.55                 Enzyme                                 

Name
3-hydroxybutyryl-CoA dehydratase;
D-3-hydroxybutyryl coenzyme A dehydratase;
D-3-hydroxybutyryl-CoA dehydratase;
enoyl coenzyme A hydrase (D);
(3R)-3-hydroxybutanoyl-CoA hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
(3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming)
Reaction(IUBMB)
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O [RN:R03027]
Reaction(KEGG)
Substrate
(3R)-3-hydroxybutanoyl-CoA [CPD:C03561]
Product
crotonoyl-CoA [CPD:C00877];
H2O [CPD:C00001]
Comment
Also acts on crotonoyl thioesters of pantetheine and acyl-carrier protein.
History
EC 4.2.1.55 created 1972
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec00650  Butanoate metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K17865  3-hydroxybutyryl-CoA dehydratase
Genes
ENR: H650_03750
CIE: AN232_13780
KSA: C813_04365
KOR: AWR26_00185
KRD: A3780_24495
HPAR: AL518_12420
PSUW: WQ53_08610
LYT: DWG18_00380
VVL: VV93_v1c03360
VPK: M636_20740
ABH: M3Q_289
SSE: Ssed_3537
SHL: Shal_2740
CPS: CPS_3371
MARJ: MARI_25330(phaJ_2)
CYQ: Q91_1228 Q91_1346(maoC)
AEH: Mlg_2811
HHA: Hhal_1055
HHK: HH1059_24760(phaJ)
ADI: B5T_04119
AXE: P40_20070
CVI: CV_3819
LHK: LHK_02914
PSE: NH8B_3503
AMAH: DLM_0091
RME: Rmet_1672
BVE: AK36_5946
BAM: Bamb_6218
BCED: DM42_2061
BCON: NL30_35025
BPH: Bphy_6753
ODI: ODI_R3784
PNA: Pnap_3284
LCH: Lcho_3597
EBA: ebA4434
DSU: Dsui_1352
DAR: Daro_3467
AZO: azo3194
AZA: AZKH_1173
AOA: dqs_3327
TCL: Tchl_0770
AMYT: AMYT_0898
ARC: ABLL_0105
DAT: HRM2_42120(maoC)
BBAC: EP01_18065
MES: Meso_1940
RIR: BN877_p0414(maoC)
BJA: blr3306
XAU: Xaut_2482
AZC: AZC_0033
MEX: Mext_3444
MEA: Mex_1p3675(croR)
MDI: METDI4248(croR)
MCH: Mchl_3753
MPO: Mpop_3642
MET: M446_5194
MNO: Mnod_5970
MOR: MOC_5744
META: Y590_16915
MAQU: Maq22A_c17200(croR)
HDN: Hden_2610
RVA: Rvan_1595
BVR: BVIR_2707
BLAG: BLTE_01590
MSC: BN69_2149
PLEO: OHA_1_01877(croR)
MCG: GL4_0954
HDI: HDIA_1083(phaJ)
RBM: TEF_16395
PZU: PHZ_c3159
SIL: SPO3152
RSP: RSP_2305
JAN: Jann_3364
RDE: RD1_3522
PDE: Pden_3661
DSH: Dshi_2926
PGD: Gal_00894
OTM: OSB_06610(phaJ)
LAQU: R2C4_12595
CID: P73_3639
MALG: MALG_02943
RHC: RGUI_1403
SPSE: SULPSESMR1_02408(phaJ)
RMM: ROSMUCSMR3_00429(phaJ)
LVS: LOKVESSMR4R_00151(phaJ)
AHT: ANTHELSMS3_02031(phaJ)
HNE: HNE_0843
HBA: Hbal_0980
GAK: X907_0954
ACR: Acry_0584
SHUM: STHU_52650(phaJ)
RRU: Rru_A2964
RRF: F11_15185
RCE: RC1_3580
MAG: amb0831
MGRY: MSR1_22260(phaJ)
MAGX: XM1_4442(phaJ)
MAGN: WV31_01260
TMO: TMO_2893
TXI: TH3_16910
MAGQ: MGMAQ_0317(phaJ)
HTL: HPTL_0565
CTC: CTC_00706(maoC)
CTET: BN906_00740(maoC)
CBE: Cbei_2038
CKL: CKL_3022
CKR: CKR_2670
CPAT: CLPA_c39950(croR)
CPAE: CPAST_c39950(croR)
CSQ: CSCA_2634
CTYK: CTK_C16670
AMT: Amet_3092
AOE: Clos_1346
CCT: CC1_14800
SWO: Swol_1356
SLP: Slip_2090
TTE: TTE0551(MaoC)
APR: Apre_0115
PHAR: NCTC13077_00525(phaJ)
PUF: UFO1_3308
PFT: JBW_01154
MANA: MAMMFC1_02836(phaJ)
STED: SPTER_29440(phaJ_1) SPTER_47280(phaJ_2)
ACL: ACL_0741
ABRA: BN85306540
MBJ: KQ51_00857(phaJ)
CAG: Cagg_0370
TAQ: TO73_0932
LIE: LIF_A3279(maoC)
LIS: LIL_13379(maoC3)
BPO: BP951000_1039(maoC)
BPW: WESB_2381
BIP: Bint_2793
FNU: FN0816
SRU: SRU_0069
SRM: SRM_00070(maoC)
RMR: Rmar_2748
HSW: Hsw_0821
CPRV: CYPRO_0733
TAF: THA_425
THER: Y592_02105
PMO: Pmob_1081
MARN: LN42_02770
KOL: Kole_0962
GAH: GAH_01713
 » show all
Taxonomy
Reference
1  [PMID:5808333]
  Authors
Moskowitz GJ, Merrick JM.
  Title
Metabolism of poly-beta-hydroxybutyrate. II. Enzymatic synthesis of D-(-)-beta hydroxybutyryl coenzyme A by an enoyl hydrase from Rhodospirillum rubrum.
  Journal
Biochemistry 8:2748-55 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.55
IUBMB Enzyme Nomenclature: 4.2.1.55
ExPASy - ENZYME nomenclature database: 4.2.1.55
BRENDA, the Enzyme Database: 4.2.1.55
CAS: 37290-82-7

KEGG   REACTION: R03027Help
Entry
R03027                      Reaction                               

Name
(3R)-3-hydroxybutanoyl-CoA hydro-lyase
Definition
(R)-3-Hydroxybutanoyl-CoA <=> Crotonoyl-CoA + H2O
Equation
Reaction class
RC00831  C00877_C03561
Enzyme
Pathway
rn00630  Glyoxylate and dicarboxylate metabolism
rn00650  Butanoate metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
rn01200  Carbon metabolism
Module
M00373  Ethylmalonyl pathway
Orthology
K17865  3-hydroxybutyryl-CoA dehydratase [EC:4.2.1.55]
Other DBs
RHEA: 17852

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