KEGG   ORTHOLOGY: K17898
Entry
K17898                      KO                                     

Name
oraE
Definition
D-ornithine 4,5-aminomutase subunit beta [EC:5.4.3.5]
Pathway
ko00472  D-Arginine and D-ornithine metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00472 D-Arginine and D-ornithine metabolism
    K17898  oraE; D-ornithine 4,5-aminomutase subunit beta
Enzymes [BR:ko01000]
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.3  Transferring amino groups
    5.4.3.5  D-ornithine 4,5-aminomutase
     K17898  oraE; D-ornithine 4,5-aminomutase subunit beta
Other DBs
RN: R02461
GO: 0047831
Genes
EAV: EH197_05070
CSQ: CSCA_0124
CACE: CACET_c17520(oraE)
CEU: A7L45_16575
CFM: BJL90_14535
CARG: RSJ17_08695
CDRK: B9W14_17920
AMT: Amet_2371
AOE: Clos_1695
GFE: Gferi_26750
CDF: CD630_04460(oraE)
PDC: CDIF630_00574(oraE)
CDC: CD196_0403(oraE)
CDL: CDR20291_0389(oraE)
PDF: CD630DERM_04460(oraE)
CST: CLOST_1290(oraE)
TTE: TTE1238(Sbm3)
THX: Thet_1422
TOC: Toce_1485
PFT: JBW_01656
MBJ: KQ51_00243(oraE)
PAC: PPA2280
PACC: PAC1_11630
CACN: RN83_00030
ABAT: CFX1CAM_0749(oraE)
TME: Tmel_0909
TAF: THA_1164
THER: Y592_05365
FNO: Fnod_1642
PMO: Pmob_1170
MARN: LN42_08190
DTN: DTL3_0763(oraE)
KOL: Kole_0360
MINF: MESINF_2280(oraE)
ASAC: ATHSA_0993
 » show all
Reference
  Authors
Wolthers KR, Levy C, Scrutton NS, Leys D
  Title
Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.
  Journal
J Biol Chem 285:13942-50 (2010)
DOI:10.1074/jbc.M109.068908
  Sequence

KEGG   ORTHOLOGY: K17899
Entry
K17899                      KO                                     

Name
oraS
Definition
D-ornithine 4,5-aminomutase subunit alpha [EC:5.4.3.5]
Pathway
ko00472  D-Arginine and D-ornithine metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00472 D-Arginine and D-ornithine metabolism
    K17899  oraS; D-ornithine 4,5-aminomutase subunit alpha
Enzymes [BR:ko01000]
 5. Isomerases
  5.4  Intramolecular transferases
   5.4.3  Transferring amino groups
    5.4.3.5  D-ornithine 4,5-aminomutase
     K17899  oraS; D-ornithine 4,5-aminomutase subunit alpha
Other DBs
RN: R02461
GO: 0047831
Genes
CBOT: ATE48_03355
EAV: EH197_05065
CSQ: CSCA_0123
CACE: CACET_c17510(oraS)
CEU: A7L45_16580
CFM: BJL90_14530
CARG: RSJ17_08690
CDRK: B9W14_17925
AMT: Amet_2370
AOE: Clos_1696
CDF: CD630_04450(oraS)
PDC: CDIF630_00573(oraS)
CDC: CD196_0402(oraS)
CDL: CDR20291_0388(oraS)
PDF: CD630DERM_04450(oraS)
CST: CLOST_1291(oraS)
TTE: TTE1237
THX: Thet_1423
TOC: Toce_1486
PFT: JBW_01655
MBJ: KQ51_00244(oraS)
PAC: PPA2279
PACC: PAC1_11625
PACH: PAGK_2188
CACN: RN83_00025
ABAT: CFX1CAM_0748(oraS)
TME: Tmel_0908
TAF: THA_1163
THER: Y592_05360
FNO: Fnod_1643
PMO: Pmob_1169
MARN: LN42_08185
DTN: DTL3_0762
KOL: Kole_0359
MINF: MESINF_2281(oraS)
ASAC: ATHSA_0994
 » show all
Reference
  Authors
Wolthers KR, Levy C, Scrutton NS, Leys D
  Title
Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.
  Journal
J Biol Chem 285:13942-50 (2010)
DOI:10.1074/jbc.M109.068908
  Sequence

KEGG   ENZYME: 5.4.3.5
Entry
EC 5.4.3.5                  Enzyme                                 

Name
D-ornithine 4,5-aminomutase;
D-alpha-ornithine 5,4-aminomutase;
D-ornithine aminomutase
Class
Isomerases;
Intramolecular transferases;
Transferring amino groups
Sysname
D-ornithine 4,5-aminomutase
Reaction(IUBMB)
D-ornithine = (2R,4S)-2,4-diaminopentanoate [RN:R02461]
Reaction(KEGG)
R02461
Substrate
D-ornithine [CPD:C00515]
Product
(2R,4S)-2,4-diaminopentanoate [CPD:C03943]
Comment
A pyridoxal-phosphate protein that requires a cobamide coenzyme for activity.
History
EC 5.4.3.5 created 1972 as EC 5.4.3.1, transferred 1976 to EC 5.4.3.5, modified 2003
Pathway
ec00472  D-Arginine and D-ornithine metabolism
ec01100  Metabolic pathways
Orthology
K17898  D-ornithine 4,5-aminomutase subunit beta
K17899  D-ornithine 4,5-aminomutase subunit alpha
Genes
CBOT: ATE48_03355
EAV: EH197_05065 EH197_05070
CSQ: CSCA_0123 CSCA_0124
CACE: CACET_c17510(oraS) CACET_c17520(oraE)
CEU: A7L45_16575 A7L45_16580
CFM: BJL90_14530 BJL90_14535
CARG: RSJ17_08690 RSJ17_08695
CDRK: B9W14_17920 B9W14_17925
AMT: Amet_2370 Amet_2371
AOE: Clos_1695 Clos_1696
CDF: CD630_04450(oraS) CD630_04460(oraE)
PDC: CDIF630_00573(oraS) CDIF630_00574(oraE)
CDC: CD196_0402(oraS) CD196_0403(oraE)
CDL: CDR20291_0388(oraS) CDR20291_0389(oraE)
CST: CLOST_1290(oraE) CLOST_1291(oraS)
TTE: TTE1237 TTE1238(Sbm3)
MBJ: KQ51_00243(oraE) KQ51_00244(oraS)
PACH: PAGK_2188
ABAT: CFX1CAM_0748(oraS) CFX1CAM_0749(oraE)
DTN: DTL3_0762 DTL3_0763(oraE)
MINF: MESINF_2280(oraE) MESINF_2281(oraS)
 » show all
Reference
1  [PMID:4711468]
  Authors
Somack R, Costilow RN.
  Title
Purification and properties of a pyridoxal phosphate and coenzyme B 12  dependent D- -ornithine 5,4-aminomutase.
  Journal
Biochemistry 12:2597-604 (1973)
DOI:10.1021/bi00738a008
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 5.4.3.5
IUBMB Enzyme Nomenclature: 5.4.3.5
ExPASy - ENZYME nomenclature database: 5.4.3.5
BRENDA, the Enzyme Database: 5.4.3.5
CAS: 62213-30-3

KEGG   REACTION: R02461
Entry
R02461                      Reaction                               

Name
D-ornithine 4,5-aminomutase
Definition
D-Ornithine <=> (2R,4S)-2,4-Diaminopentanoate
Equation
Reaction class
RC00719  C00515_C03943
Enzyme
Pathway
rn00472  D-Arginine and D-ornithine metabolism
rn01100  Metabolic pathways
Orthology
K17898  D-ornithine 4,5-aminomutase subunit beta [EC:5.4.3.5]
K17899  D-ornithine 4,5-aminomutase subunit alpha [EC:5.4.3.5]
Other DBs
RHEA: 14896

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