KEGG   ORTHOLOGY: K18028
Entry
K18028                      KO                                     

Name
nicX
Definition
2,5-dihydroxypyridine 5,6-dioxygenase [EC:1.13.11.9]
Pathway
ko00760  Nicotinate and nicotinamide metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Module
M00622  Nicotinate degradation, nicotinate => fumarate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K18028  nicX; 2,5-dihydroxypyridine 5,6-dioxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.9  2,5-dihydroxypyridine 5,6-dioxygenase
     K18028  nicX; 2,5-dihydroxypyridine 5,6-dioxygenase
Other DBs
RN: R09125
GO: 0047075
Genes
GQU: AWC35_02975
SMAR: SM39_1771
SMAC: SMDB11_1584
SMW: SMWW4_v1c23260
SPE: Spro_2312
SRR: SerAS9_2269
SRL: SOD_c21420(nicX)
SRY: M621_11735
SPLY: Q5A_011870(nicX)
SRS: SerAS12_2269
SERF: L085_17115
PPU: PP_3945(nicX)
PPF: Pput_1892
PPT: PPS_4058
PPI: YSA_08963
PPX: T1E_5122
PPUT: L483_21715
PPUN: PP4_17770
PFS: PFLU_2800
PFB: VO64_0127
PANR: A7J50_2717
PSIL: PMA3_12570
AGU: AS4_40080
HAM: HALO0548
ADI: B5T_02297
REH: H16_A0925(h16_A0925) H16_B0813(h16_B0813)
CGD: CR3_0803(ampS) CR3_3007(nicX)
BCN: Bcen_4327
BCJ: BCAM1142
BCEN: DM39_3879
BCEO: I35_4989
BMU: Bmul_4550
BMK: DM80_3720
BMUL: NP80_4069
BCED: DM42_3948
BCON: NL30_06920
BSEM: WJ12_25610
BPSL: WS57_08415
BMEC: WJ16_24240
BSTG: WT74_20825
BGO: BM43_2599
BXE: Bxe_C0216
BXB: DR64_8215
BFN: OI25_6799
PPNO: DA70_23280
PPNM: LV28_07430
PPUL: RO07_01615
PAPI: SG18_01755
CABA: SBC2_37490(nicX_1) SBC2_53530(nicX_2)
BPET: B1917_3473
BHZ: ACR54_00920(nicX)
AFQ: AFA_13575 AFA_14965(nicX) AFA_15135(picD) AFA_18565(hpaX)
ODI: ODI_R3898
AAV: Aave_3930
AAA: Acav_3827
DAC: Daci_1850
CTES: O987_23190
HYB: Q5W_22175
HPSE: HPF_00905(nicX)
RLG: Rleg_6046
SHZ: shn_30285
OCH: CES85_3503(nicX)
BRA: BRADO2312
BRS: S23_21870
AOL: S58_52840
BRAD: BF49_5545
SNO: Snov_3511
PHL: KKY_3788
PLEO: OHA_1_03169(nicX)
HDI: HDIA_0234(nicX)
CID: P73_3892
LVS: LOKVESSMR4R_03232(nicX)
MALU: KU6B_06560
GXL: H845_1042
KEU: S101446_01672(nicX)
KSC: CD178_02878(nicX)
MGM: Mmc1_1162
CSO: CLS_30390
BPRM: CL3_19660
CHY: CHY_0589
PUF: UFO1_4548
MVQ: MYVA_3797
RFA: A3L23_03312(nicX)
RHS: A3Q41_00020(nicX)
SALU: DC74_1449
SALL: SAZ_07780
STRE: GZL_07763
SMAL: SMALA_0613
FAL: FRAAL6169
AOI: AORI_4776
AJA: AJAP_15760(nicX)
AMYY: YIM_29130(nicX)
PSEA: WY02_22100
PSEE: FRP1_20590
PSEH: XF36_05315
PAUT: Pdca_13590
FLM: MY04_5148
TLE: Tlet_1501
PHO: PH1046(PH1046)
TLT: OCC_03863
THS: TES1_1600
KCR: Kcr_0404
BARC: AOA65_1270
 » show all
Reference
PMID:5578917
  Authors
Gauthier JJ, Rittenberg SC
  Title
The metabolism of nicotinic acid. I. Purification and properties of 2,5-dihydroxypyridine oxygenase from Pseudomonas putida N-9.
  Journal
J Biol Chem 246:3737-42 (1971)
  Sequence
[ppu:PP_3945]
Reference
  Authors
Jimenez JI, Canales A, Jimenez-Barbero J, Ginalski K, Rychlewski L, Garcia JL, Diaz E
  Title
Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440.
  Journal
Proc Natl Acad Sci U S A 105:11329-34 (2008)
DOI:10.1073/pnas.0802273105
  Sequence
[ppu:PP_3945]

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