KEGG   ORTHOLOGY: K18050Help
Entry
K18050                      KO                                     

Name
PRKCE
Definition
novel protein kinase C epsilon type [EC:2.7.11.13]
Pathway
ko04022  cGMP-PKG signaling pathway
ko04071  Sphingolipid signaling pathway
ko04270  Vascular smooth muscle contraction
ko04371  Apelin signaling pathway
ko04530  Tight junction
ko04666  Fc gamma R-mediated phagocytosis
ko04750  Inflammatory mediator regulation of TRP channels
ko04925  Aldosterone synthesis and secretion
ko04930  Type II diabetes mellitus
ko04931  Insulin resistance
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K18050  PRKCE; novel protein kinase C epsilon type
   04071 Sphingolipid signaling pathway
    K18050  PRKCE; novel protein kinase C epsilon type
   04022 cGMP-PKG signaling pathway
    K18050  PRKCE; novel protein kinase C epsilon type
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K18050  PRKCE; novel protein kinase C epsilon type
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    K18050  PRKCE; novel protein kinase C epsilon type
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    K18050  PRKCE; novel protein kinase C epsilon type
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K18050  PRKCE; novel protein kinase C epsilon type
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K18050  PRKCE; novel protein kinase C epsilon type
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K18050  PRKCE; novel protein kinase C epsilon type
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    K18050  PRKCE; novel protein kinase C epsilon type
   04931 Insulin resistance
    K18050  PRKCE; novel protein kinase C epsilon type
   04933 AGE-RAGE signaling pathway in diabetic complications
    K18050  PRKCE; novel protein kinase C epsilon type
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K18050  PRKCE; novel protein kinase C epsilon type
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     K18050  PRKCE; novel protein kinase C epsilon type
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   K18050  PRKCE; novel protein kinase C epsilon type
BRITE hierarchy
Other DBs
GO: 0004699
Genes
HSA: 5581(PRKCE)
PTR: 459203(PRKCE)
PPS: 100974922(PRKCE)
GGO: 101133595(PRKCE)
PON: 100440778(PRKCE)
NLE: 100606298(PRKCE)
MCC: 714533(PRKCE)
MCF: 102127282(PRKCE)
CSAB: 103220351(PRKCE)
RRO: 104663184(PRKCE)
RBB: 108522504(PRKCE)
CJC: 100388620(PRKCE) 103787972
SBQ: 101053832(PRKCE)
MMU: 18754(Prkce)
MCAL: 110312510(Prkce)
MPAH: 110336160(Prkce)
RNO: 29340(Prkce)
CGE: 100763552(Prkce)
NGI: 103725757(Prkce)
HGL: 101700837(Prkce)
OCU: 100009103(PRKCE)
TUP: 102502025(PRKCE)
CFA: 609934(PRKCE)
VVP: 112915218(PRKCE)
AML: 100468967(PRKCE)
UMR: 103671225(PRKCE)
UAH: 113246159(PRKCE)
ORO: 101362539(PRKCE)
FCA: 101100958(PRKCE)
PTG: 102956451(PRKCE)
AJU: 106977232(PRKCE)
BTA: 507041(PRKCE)
BOM: 102266941(PRKCE) 102283594
BIU: 109566044(PRKCE)
BBUB: 102404606(PRKCE)
PHD: 102316645(PRKCE)
CHX: 102169016(PRKCE)
OAS: 101110314(PRKCE)
SSC: 100524932(PRKCE)
CFR: 102509837(PRKCE)
CDK: 105103566(PRKCE)
BACU: 103006250(PRKCE)
LVE: 103068913(PRKCE)
OOR: 101276402(PRKCE)
DLE: 111174803(PRKCE)
ECB: 100053394(PRKCE)
EPZ: 103549602(PRKCE)
EAI: 106826113(PRKCE)
MYB: 102263707(PRKCE)
MYD: 102759931(PRKCE)
HAI: 109393868(PRKCE)
RSS: 109456372(PRKCE)
DRO: 112297947(PRKCE)
PALE: 102894641(PRKCE)
RAY: 107509571(PRKCE)
LAV: 100655386(PRKCE) 104846440
TMU: 101349247
MDO: 100032210(PRKCE)
SHR: 100921656(PRKCE)
PCW: 110218526(PRKCE)
OAA: 103168168(PRKCE)
GGA: 421409(PRKCE)
MGP: 100543758(PRKCE)
CJO: 107311186(PRKCE)
NMEL: 110395486(PRKCE)
APLA: 101795629(PRKCE)
ACYG: 106029794(PRKCE)
TGU: 100230589(PRKCE)
LSR: 110478027(PRKCE) 110480403
SCAN: 103817167(PRKCE)
GFR: 102031365(PRKCE)
FAB: 101815711(PRKCE)
PHI: 102110578(PRKCE)
PMAJ: 107202015(PRKCE)
CCAE: 111927602(PRKCE)
CCW: 104685689(PRKCE)
FPG: 101917755(PRKCE)
FCH: 102059448(PRKCE)
CLV: 102096207(PRKCE)
EGZ: 104123423(PRKCE)
NNI: 104019696(PRKCE)
ACUN: 113478353(PRKCE)
PADL: 103914308(PRKCE) 103918098
AAM: 106485510(PRKCE)
ASN: 102368989(PRKCE)
AMJ: 102576791(PRKCE)
PSS: 102452906(PRKCE)
CMY: 102936130(PRKCE)
CPIC: 101951149(PRKCE)
ACS: 100567346(prkce)
PBI: 103053780 103060295(PRKCE)
PMUR: 107287861(PRKCE)
XLA: 108717735
XTR: 100135720(prkce)
NPR: 108804505(PRKCE)
DRE: 100005075(prkcea) 100332055(prkceb)
IPU: 108263296 108274197(Prkce)
PHYP: 113527396 113543727(prkce)
TRU: 101067313 101073327(prkce)
LCO: 104922490(prkce) 104931840
OLA: 101168247(prkce) 101172355
XMA: 102224280 102236119(prkce)
XCO: 114137801 114151921(prkce)
PRET: 103476621 103481826(prkce)
NFU: 107387753(prkce)
KMR: 108249079(prkce)
AOCE: 111562817 111577888(prkce)
CSEM: 103381531(prkce) 103387794
LCF: 108872883 108882782(prkce)
SDU: 111219758(prkce) 111223864
HCQ: 109510070 109530172(prkce)
BPEC: 110162858 110174578(prkce)
MALB: 109963057(prkce) 109963810
OTW: 112223228 112224582(prkce)
ELS: 105006029 105021252(prkce)
SFM: 108918044(prkce)
PKI: 111839985(prkce)
CMK: 103180812(prkce) 103185381(prkch)
CIN: 100180034
SPU: 100890668
SKO: 100368048
DME: Dmel_CG1954(Pkc98E)
DER: 6555094
DPE: 6587588
DSI: Dsimw501_GD21405(Dsim_GD21405)
DWI: 6649805
DAZ: 108612531
DNV: 108656188
DHE: 111596253
MDE: 101897861
LCQ: 111675427
AAG: 5566886
AME: 724607
BIM: 100746850
BTER: 100648553
SOC: 105196123
MPHA: 105836872
AEC: 105152158
PBAR: 105428546
VEM: 105559594
HST: 105186100
DQU: 106740941
CFO: 105252927
LHU: 105674898
PGC: 109854089
OBO: 105278001
PCF: 106791791
NVI: 100114311
MDL: 103576073
TCA: 103313855 663551(Pkc98E)
DPA: 109545127
NVL: 108568604
BMOR: 101737153
PRAP: 111003925
HAW: 110377339
TNL: 113504898
API: 100160881
DNX: 107168577
AGS: 114128427
CLEC: 106664731
ZNE: 110829995
FCD: 110845195
CEL: CELE_F57F5.5(pkc-1)
CBR: CBG23354(Cbr-pkc-1)
BMY: Bm1_52195
PCAN: 112570974
MYI: 110454924
LAK: 106173307
EGL: EGR_00318
EPA: 110250830
PDAM: 113681488
SPIS: 111329101
HMG: 100208590
AQU: 100633428
ANI: AN0106.2
ANG: ANI_1_290164(An18g02400)
SPO: SPBC12D12.04c(pck2)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2917656
  Authors
Schaap D, Parker PJ, Bristol A, Kriz R, Knopf J
  Title
Unique substrate specificity and regulatory properties of PKC-epsilon: a rationale for diversity.
  Journal
FEBS Lett 243:351-7 (1989)
DOI:10.1016/0014-5793(89)80160-7
  Sequence
[mmu:18754]

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