ORTHOLOGY: K18072 Help
Entry
Symbol
parS
Name
two-component system, OmpR family, sensor kinase ParS [EC:
2.7.13.3 ]
Pathway
map01503 Cationic antimicrobial peptide (CAMP) resistance
Module
M00745 Imipenem resistance, repression of porin OprD
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09130 Environmental Information Processing
09132 Signal transduction
02020 Two-component system
K18072 parS; two-component system, OmpR family, sensor kinase ParS
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
K18072 parS; two-component system, OmpR family, sensor kinase ParS
01503 Cationic antimicrobial peptide (CAMP) resistance
K18072 parS; two-component system, OmpR family, sensor kinase ParS
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases
K18072 parS; two-component system, OmpR family, sensor kinase ParS
09183 Protein families: signaling and cellular processes
02022 Two-component system
K18072 parS; two-component system, OmpR family, sensor kinase ParS
01504 Antimicrobial resistance genes
K18072 parS; two-component system, OmpR family, sensor kinase ParS
Enzymes [BR:ko01000 ]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.13 Protein-histidine kinases
2.7.13.3 histidine kinase
K18072 parS; two-component system, OmpR family, sensor kinase ParS
Protein kinases [BR:ko01001 ]
Histidine kinases
OmpR family
K18072 parS; two-component system, OmpR family, sensor kinase ParS
Two-component system [BR:ko02022 ]
OmpR family
ParS-ParR (polymyxin-adaptive resistance)
K18072 parS; two-component system, OmpR family, sensor kinase ParS
Antimicrobial resistance genes [BR:ko01504 ]
Gene sets
beta-Lactam resistance modules
Imipenem resistance, repression of porin OprD
K18072 parS; two-component system, OmpR family, sensor kinase ParS
BRITE hierarchy
Other DBs
Genes
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Taxonomy UniProt
Reference
Authors
Muller C, Plesiat P, Jeannot K
Title
A two-component regulatory system interconnects resistance to polymyxins, aminoglycosides, fluoroquinolones, and beta-lactams in Pseudomonas aeruginosa.
Journal
Sequence
Reference
Authors
Fernandez L, Hancock RE
Title
Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance.
Journal
Reference
Authors
Vettoretti L, Plesiat P, Muller C, El Garch F, Phan G, Attree I, Ducruix A, Llanes C
Title
Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Journal