KEGG   ORTHOLOGY: K18104
Entry
K18104                      KO                                     

Name
abcA, bmrA
Definition
ATP-binding cassette, subfamily B, bacterial AbcA/BmrA [EC:7.6.2.2]
Pathway
ko01501  beta-Lactam resistance
ko02010  ABC transporters
Module
M00700  Multidrug resistance, efflux pump AbcA
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K18104  abcA, bmrA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K18104  abcA, bmrA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K18104  abcA, bmrA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA
   01504 Antimicrobial resistance genes
    K18104  abcA, bmrA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA
Enzymes [BR:ko01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.2  ABC-type xenobiotic transporter
     K18104  abcA, bmrA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA
Transporters [BR:ko02000]
 ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB-BAC subgroup
    K18104  abcA, bmrA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump AbcA
    K18104  abcA, bmrA; ATP-binding cassette, subfamily B, bacterial AbcA/BmrA
Other DBs
COG: COG1132
GO: 0008559
TC: 3.A.1.117 3.A.1.123
Genes
XDO: XDD1_2169
STES: MG068_19595
LAB: LA76x_2690(bmrA)
LAQ: GLA29479_2958(bmrA)
LCP: LC55x_2720(bmrA)
LGU: LG3211_2478(bmrA)
LEZ: GLE_3673
LEM: LEN_2611 LEN_2645
PPHE: PP2015_3280
PPIS: B1L02_21300
PSEN: PNC201_20185(bmrA)
PBH: AAW51_3369(abcA)
SBF: JCM31447_04910(mdlB)
BSU: BSU34820(bmrA)
BSR: I33_3609
BSL: A7A1_2702
BSH: BSU6051_34820(bmrA)
BSUT: BSUB_03712(bmrA)
BSUL: BSUA_03712(bmrA)
BSUS: Q433_01255(subT) Q433_19065
BSS: BSUW23_17065(bmrA)
BST: GYO_3818
BSO: BSNT_10109(yvcC)
BSQ: B657_34820(bmrA)
BSX: C663_0485(bmrA) C663_3370(yvcC)
BLI: BL02726(bmrA)
BLD: BLi00213(bmrA)
BLH: BaLi_c02350(bmrA)
BAQ: BACAU_3235(yvcC)
BYA: BANAU_3388(yvcC)
BAMP: B938_16470
BAML: BAM5036_3120(bmrA)
BAMA: RBAU_3343(bmrA)
BAMN: BASU_3121(bmrA)
BAMB: BAPNAU_3396(yvcC)
BAMT: AJ82_18135
BAMY: V529_34740(yvcC)
BMP: NG74_03373(bmrA)
BAO: BAMF_0777(yvcC) BAMF_3331(bmrA)
BAZ: BAMTA208_03695(yvcC) BAMTA208_17670(bmrA)
BQL: LL3_00829(yvcC) LL3_03624(bmrA)
BQY: MUS_3824(yvcC)
BAMI: KSO_003065
BAMC: U471_33320
BAMF: U722_17205
BSON: S101395_04830(abcA)
BHA: BH0713
BANT: A16_19930
BANR: A16R_20150
BANS: BAPAT_1868
BANV: DJ46_763
BCE: BC1955
BCA: BCE_2040
BCQ: BCQ_1946
BCX: BCA_2020
BNC: BCN_1872
BCF: bcf_09630
BCER: BCK_24765
BTL: BALH_1731
BTT: HD73_2120
BTHI: BTK_10705
BTG: BTB_c20240(bmrA)
BTW: BF38_3172(bmrA)
BWW: bwei_3059(bmrA)
BMYO: BG05_4026
BPU: BPUM_2353
BMQ: BMQ_2979(bmrA)
BMD: BMD_3007(bmrA)
BMEG: BG04_5510
BJS: MY9_3525
BACP: SB24_12700
BACB: OY17_19330
BACO: OXB_0523
BACY: QF06_15795
BACL: BS34A_37920(bmrA)
BALM: BsLM_3489
BGY: BGLY_0196(bmrA)
BKW: BkAM31D_07775(bmrA)
OIH: OB0426
LSP: Bsph_2065
VPN: A21D_00787(bmrA)
PSYO: PB01_06100
SAU: SA0599
SAV: SAV0643
SAW: SAHV_0640
SAM: MW0605
SAS: SAS0609
SAR: SAR0653
SAC: SACOL0700(abcA)
SAE: NWMN_0613
SAD: SAAV_0606(abcA)
SUE: SAOV_0678(abcA)
SUJ: SAA6159_00598(abcA)
SUK: SAA6008_00660(abcA)
SUC: ECTR2_595
SUZ: MS7_0694(bmrA)
SUW: SATW20_07180(abcA)
SUG: SAPIG0722
SUF: SARLGA251_05770(abcA)
SAUA: SAAG_01066
SAUS: SA40_0584(abcA)
SAUU: SA957_0599(abcA)
SAUG: SA268_0597(abcA)
SAUZ: SAZ172_0655(abcA)
SAUT: SAI1T1_2004960(abcA)
SAUJ: SAI2T2_1004980(abcA)
SAUK: SAI3T3_1004970(abcA)
SAUQ: SAI4T8_1004960(abcA)
SAUF: X998_0691
SAB: SAB0593
SUY: SA2981_0619(msbA)
SAUB: C248_0725
SAUM: BN843_6450
SAUC: CA347_657(bmrA)
SAUR: SABB_00691(bmrA)
SAUI: AZ30_03370
SAUD: CH52_02545
SAMS: NI36_03220
SER: SERP0303(abcA)
SEPP: SEB_00337
SEPS: DP17_1720
SHA: SH2253
SHH: ShL2_02102(abcA)
SSP: SSP2076
SCA: SCA_0292
SLN: SLUG_21550(abcA)
SDT: SPSE_2104
SPAS: STP1_1729
SCAP: AYP1020_0011(bmrA)
SSCH: LH95_10085
SSCZ: RN70_10820
SAGQ: EP23_11680
SDP: NCTC12225_02323(bmrA)
LMO: lmo2745
LMOE: BN418_3250
LMOB: BN419_3267
LMOD: LMON_2767
LMOW: AX10_07900
LMOQ: LM6179_0159(bmrA)
LMR: LMR479A_2882(bmrA)
LMOM: IJ09_10980
LMOG: BN389_27200(bmrA)
LMP: MUO_13785
LMOX: AX24_11860
LMQ: LMM7_2856(msbA)
LMS: LMLG_0280
LMOK: CQ02_14045
LIN: lin2888
LWE: lwe2693
LSG: lse_2658
LIV: LIV_2698
LGZ: NCTC10812_00054(bmrA_1)
ESI: Exig_1154
EAN: Eab7_1116
BBE: BBR47_41950(yvcC)
PPY: PPE_03603
PPM: PPSC2_05730(yvcC1) PPSC2_19100(yvcC3)
PPO: PPM_1078(yvcC1) PPM_3840(yvcC3)
PPOL: X809_35175
PMW: B2K_23480
PSAB: PSAB_22645
PRI: PRIO_6359(bmrA)
PSWU: SY83_10155
SIV: SSIL_0331
JEO: JMA_08120
KUR: ASO14_180
KZO: NCTC404_01023(bmrA)
LLA: L116532(lmrA)
LLK: LLKF_0728(lmrA)
LLT: CVCAS_0665(lmrA)
LLS: lilo_0645(lmrA)
LLX: NCDO2118_0726(lmrA)
LLM: llmg_1856(lmrA)
LLR: llh_9360
LLW: kw2_0653
LLJ: LG36_0695(lmrA)
LGR: LCGT_0296
LGV: LCGL_0296
SPNN: T308_06930
SNP: SPAP_1549
SSI: SSU0044
SUP: YYK_00215
SSUY: YB51_0260
SSUT: TL13_0064(msbA)
SIB: SIR_1566
SIU: SII_1552
LPJ: JDM1_2010 JDM1_2375(lmrA)
LJO: LJ_1157
LAC: LBA0597
LAD: LA14_0626
LAF: SD55_0620
LSA: LCA_0232(lmrA)
LDB: Ldb0031
LBU: LBUL_0024
LBR: LVIS_1995
LCA: LSEI_2132
LCS: LCBD_2298(tagA)
LCE: LC2W_2280(tagA)
LPAP: LBPC_2067
LCB: LCABL_23130(horA_homolog)
LCW: BN194_22720(lmrA)
LRE: Lreu_0018
LRF: LAR_0017
LRT: LRI_0022
LBH: Lbuc_2036
LSN: LSA_05020(lmrA)
PPE: PEPE_1658
PPEN: T256_08160
PCE: PECL_1953(horA)
EFS: EFS1_2572
ENE: ENT_28870
EHR: EHR_01070
ECAS: ECBG_03129
MPS: MPTP_1913
MPX: MPD5_1706
OOE: OEOE_1345
LCI: LCK_00921(lmrA)
LGS: LEGAS_0091(LRMA)
WKO: WKK_06145
CML: BN424_752(bmrA)
JDA: BW727_200001(bmrA)
CBL: CLK_0162
CLD: CLSPO_c07850(lmrA1)
CDP: CD241_0065(lmrA)
CDT: CDHC01_0064(lmrA)
BPSC: BBPC_1104
ELB: VO54_03321(yheI_2)
SRG: XF24_00164(bmrA)
 » show all
Reference
  Authors
Lewis VG, Ween MP, McDevitt CA
  Title
The role of ATP-binding cassette transporters in bacterial pathogenicity.
  Journal
Protoplasma 249:919-42 (2012)
DOI:10.1007/s00709-011-0360-8
Reference
  Authors
Truong-Bolduc QC, Hooper DC
  Title
The transcriptional regulators NorG and MgrA modulate resistance to both quinolones and beta-lactams in Staphylococcus aureus.
  Journal
J Bacteriol 189:2996-3005 (2007)
DOI:10.1128/JB.01819-06

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