KEGG   ORTHOLOGY: K18130
Entry
K18130                      KO                                     

Name
nalC
Definition
TetR/AcrR family transcriptional regulator, transcriptional repressor NalC
Pathway
ko01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K18130  nalC; TetR/AcrR family transcriptional regulator, transcriptional repressor NalC
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K18130  nalC; TetR/AcrR family transcriptional regulator, transcriptional repressor NalC
Transcription factors [BR:ko03000]
 Prokaryotic type
  Helix-turn-helix
   TetR/AcrR family
    K18130  nalC; TetR/AcrR family transcriptional regulator, transcriptional repressor NalC
Other DBs
COG: COG1309
Genes
PSI: S70_19845
PSX: DR96_2878
PVC: G3341_11465
MMK: MU9_1961
PAE: PA3721(nalC)
PAEV: N297_3844
PAEI: N296_3844
PAU: PA14_16280
PAP: PSPA7_1400
PAG: PLES_12611
PAEP: PA1S_06490
PAEM: U769_06280
PAEL: T223_06215
PAEG: AI22_27100
PAEC: M802_3841
PAEO: M801_3709
 » show all
Reference
  Authors
Cao L, Srikumar R, Poole K
  Title
MexAB-OprM hyperexpression in NalC-type multidrug-resistant Pseudomonas aeruginosa: identification and characterization of the nalC gene encoding a repressor of PA3720-PA3719.
  Journal
Mol Microbiol 53:1423-36 (2004)
DOI:10.1111/j.1365-2958.2004.04210.x
  Sequence
[pae:PA3721]
Reference
  Authors
Fernandez L, Hancock RE
  Title
Adaptive and mutational resistance: role of porins and efflux pumps in drug resistance.
  Journal
Clin Microbiol Rev 25:661-81 (2012)
DOI:10.1128/CMR.00043-12

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