KEGG   ORTHOLOGY: K18149
Entry
K18149                      KO                                     

Name
pbp5, pbp4, pbp3
Definition
penicillin-binding protein
Pathway
ko00550  Peptidoglycan biosynthesis
ko01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    K18149  pbp5, pbp4, pbp3; penicillin-binding protein
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    K18149  pbp5, pbp4, pbp3; penicillin-binding protein
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins
    K18149  pbp5, pbp4, pbp3; penicillin-binding protein
Peptidoglycan biosynthesis and degradation proteins [BR:ko01011]
 Peptidoglycan biosynthesis and degradation
  DD-Transpeptidase (Class B PBP)
   K18149  pbp5, pbp4, pbp3; penicillin-binding protein
Other DBs
COG: COG0768
GO: 0008658
Genes
EFA: EF2476
EFL: EF62_2694
EFI: OG1RF_11907
EFD: EFD32_2093
EFS: EFS1_1997
EFN: DENG_02455
EFQ: DR75_1224
ENE: ENT_16890
EFC: EFAU004_00870
EFAU: EFAU085_01479
EFU: HMPREF0351_11456(pbp5)
EFM: M7W_1949
EHR: EHR_11450
ECAS: ECBG_02140
EMU: EMQU_1462(pbp5)
ESG: EsVE80_03690(pbp5)
MPX: MPD5_0685
WKO: WKK_05005
 » show all
Reference
  Authors
Galloway-Pena JR, Rice LB, Murray BE
  Title
Analysis of PBP5 of early U.S. isolates of Enterococcus faecium: sequence variation alone does not explain increasing ampicillin resistance over time.
  Journal
Antimicrob Agents Chemother 55:3272-7 (2011)
DOI:10.1128/AAC.00099-11
  Sequence
Reference
  Authors
Ono S, Muratani T, Matsumoto T
  Title
Mechanisms of resistance to imipenem and ampicillin in Enterococcus faecalis.
  Journal
Antimicrob Agents Chemother 49:2954-8 (2005)
DOI:10.1128/AAC.49.7.2954-2958.2005
  Sequence
[efq:DR75_1224]
Reference
PMID:8491705
  Authors
Piras G, Raze D, el Kharroubi A, Hastir D, Englebert S, Coyette J, Ghuysen JM
  Title
Cloning and sequencing of the low-affinity penicillin-binding protein 3r-encoding gene of Enterococcus hirae S185: modular design and structural organization of the protein.
  Journal
J Bacteriol 175:2844-52 (1993)
DOI:10.1128/JB.175.10.2844-2852.1993

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