KEGG   ORTHOLOGY: K18245
Entry
K18245                      KO                                     

Name
CA2
Definition
carbonic anhydrase 2 [EC:4.2.1.1]
Pathway
ko00910  Nitrogen metabolism
ko01100  Metabolic pathways
ko04964  Proximal tubule bicarbonate reclamation
ko04966  Collecting duct acid secretion
ko04971  Gastric acid secretion
ko04972  Pancreatic secretion
ko04976  Bile secretion
Disease
H00241  Combined proximal and distal renal tubular acidosis
H00436  Osteopetrosis
H02310  Renal tubular acidosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00910 Nitrogen metabolism
    K18245  CA2; carbonic anhydrase 2
 09150 Organismal Systems
  09154 Digestive system
   04971 Gastric acid secretion
    K18245  CA2; carbonic anhydrase 2
   04972 Pancreatic secretion
    K18245  CA2; carbonic anhydrase 2
   04976 Bile secretion
    K18245  CA2; carbonic anhydrase 2
  09155 Excretory system
   04964 Proximal tubule bicarbonate reclamation
    K18245  CA2; carbonic anhydrase 2
   04966 Collecting duct acid secretion
    K18245  CA2; carbonic anhydrase 2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K18245  CA2; carbonic anhydrase 2
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.1  carbonic anhydrase
     K18245  CA2; carbonic anhydrase 2
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K18245  CA2; carbonic anhydrase 2
Other DBs
RN: R10092
GO: 0004089
Genes
HSA: 760(CA2)
PTR: 450162(CA2)
PPS: 103782648(CA2)
GGO: 101130277(CA2)
PON: 100439372(CA2)
NLE: 100597559(CA2)
MCC: 574263(CA2)
MCF: 101866067(CA2)
CSAB: 103237071(CA2)
RRO: 104676872(CA2)
RBB: 108513910(CA2)
CJC: 100399152(CA2)
SBQ: 101051669(CA2)
MMU: 12349(Car2)
MCAL: 110290838(Ca2)
MPAH: 110320114(Ca2)
RNO: 54231(Car2)
MUN: 110565873
CGE: 100774844(Ca2)
NGI: 103737199(Ca2)
HGL: 101697802(Ca2)
CCAN: 109696006(Ca2)
OCU: 100009156(CA2)
TUP: 102489985(CA2)
CFA: 477928(CA2)
VVP: 112931543(CA2)
AML: 100474697(CA2)
UMR: 103661462(CA2)
UAH: 113252986(CA2)
ORO: 101373598(CA2)
ELK: 111146638
FCA: 101094903(CA2)
PTG: 102955030(CA2)
PPAD: 109269438(CA2)
AJU: 106982309(CA2)
BTA: 280740(CA2)
BOM: 102266781(CA2)
BIU: 109568598(CA2)
BBUB: 102416531(CA2)
CHX: 102174762(CA2)
OAS: 101113341(CA2)
SSC: 100154873
CFR: 102512347(CA2)
CDK: 105088502(CA2)
BACU: 103014000(CA2)
LVE: 103077109(CA2)
OOR: 101289174(CA2)
DLE: 111164950(CA2)
PCAD: 102986103(CA2)
ECB: 100050059(CA2)
EPZ: 103566710(CA2)
EAI: 106829849(CA2)
MYB: 102262761(CA2)
MYD: 102764293(CA2)
MNA: 107526484(CA2)
DRO: 112320764(CA2)
PALE: 102895979(CA2)
RAY: 107514919(CA2)
MJV: 108401866(CA2)
LAV: 100662562(CA2)
TMU: 101349680
MDO: 100025850(CA2)
SHR: 100918259
PCW: 110214700(CA2)
OAA: 100075583(CA2)
GGA: 396257(CA2)
CJO: 107310310
NMEL: 110393964
APLA: 101802744
ACYG: 106030632
TGU: 100224950
LSR: 110477417
SCAN: 103813316
GFR: 102038402(CA2)
FAB: 101818231(CA2)
PHI: 102102545(CA2)
PMAJ: 107200179
CCAE: 111924584
CCW: 104692773
ETL: 114065898(CA2)
FPG: 101919433(CA2)
FCH: 102050825
CLV: 102091786
EGZ: 104123327(CA2)
NNI: 104022793(CA2)
ACUN: 113476157
PADL: 103924062(CA2)
AAM: 106496231
ASN: 102376447(CA2)
AMJ: 102559447(CA2)
PSS: 102453298(CA2)
CMY: 102930688(CA2)
CPIC: 101931774 101938201(CA2)
ACS: 100552322(ca2)
PVT: 110086873
PBI: 103065165
PMUR: 107294436(CA2) 107301657
TSR: 106540908(CA2)
PMUA: 114600457(CA2)
GJA: 107122376(CA2)
XLA: 108719319 379058(ca2.S) 379772(ca2.L) 496283
XTR: 548446(ca2) 780246(car1_predicted)
NPR: 108786473
DRE: 30331(cahz) 387526(ca2)
IPU: 100528361(cahz) 108265147(ca2)
EEE: 113575687(ca2)
PRET: 103456787
PKI: 111838699 111846202(ca2)
CMK: 103184961
SPU: 577690
AAG: 5566891
AALB: 109622044
NVI: 100123691
BMOR: 101745801
PMAC: 106720239
PRAP: 111004159
PXY: 105380620
PVM: 113817163
DPTE: 113789526
BMY: Bm1_32535
PCAN: 112553390
CRG: 105342594
OBI: 106879616
EGL: EGR_07248
AQU: 100631784
 » show all
Reference
  Authors
Alvarez BV, Vilas GL, Casey JR
  Title
Metabolon disruption: a mechanism that regulates bicarbonate transport.
  Journal
EMBO J 24:2499-511 (2005)
DOI:10.1038/sj.emboj.7600736
  Sequence
[hsa:760]

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