KEGG   ORTHOLOGY: K18290
Entry
K18290                      KO                                     
Symbol
ich-Y
Name
itaconyl-CoA hydratase [EC:4.2.1.56]
Pathway
map00660  C5-Branched dibasic acid metabolism
map01100  Metabolic pathways
Reaction
R02491  (3S)-citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    K18290  ich-Y; itaconyl-CoA hydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.56  itaconyl-CoA hydratase
     K18290  ich-Y; itaconyl-CoA hydratase
Other DBs
COG: COG2030
GO: 0050011
Genes
STM: STM3119
SEO: STM14_3768
SEV: STMMW_30791
SEY: SL1344_3093
SEM: STMDT12_C31720
SEJ: STMUK_3107
SEB: STM474_3268
SEF: UMN798_3389
SETU: STU288_15785
SETC: CFSAN001921_01430
SENR: STMDT2_30131
SEND: DT104_31151
SENI: CY43_16260
SEEN: SE451236_21710
SPQ: SPAB_03889
SEI: SPC_3186
SEC: SCH_3059(maoC)
SEH: SeHA_C3361
SHB: SU5_03617
SENH: CFSAN002069_16555
SEEH: SEEH1578_01720
SEE: SNSL254_A3368
SENN: SN31241_42430
SEW: SeSA_A3294
SED: SeD_A3463
SEG: SG3013
SEL: SPUL_3122
SEGA: SPUCDC_3108
SET: SEN2962
SENA: AU38_15055
SENO: AU37_15065
SENV: AU39_15060
SENQ: AU40_16975
SENL: IY59_15665
SENJ: CFSAN001992_17980
SEEB: SEEB0189_004285
SEEP: I137_14920
SENB: BN855_31910
SENE: IA1_15055
SES: SARI_04512
SALZ: EOS98_03725
YPE: YPO1927
YPK: y2384
YPA: YPA_1305
YPM: YP_1669(maoC)
YPP: YPDSF_1197
YPG: YpAngola_A2117
YPD: YPD4_1694
YPX: YPD8_1854
YPW: CH59_3723
YPV: BZ15_1615
YPL: CH46_3188
YPS: YPTB1925
YPO: BZ17_546
YPI: YpsIP31758_2157
YPY: YPK_2267
YPB: YPTS_1974
YPQ: DJ40_390
YPU: BZ21_1196
YPR: BZ20_193
YPC: BZ23_1479
YPF: BZ19_1271
YSI: BF17_18435
SPE: Spro_3023
SLQ: M495_15430
SQU: E4343_00900
SENP: KHA73_09775(ripB)
SGRI: SGBXF1_03031(paaZ_1)
SOD: Sant_0822
XHO: A9255_04215
STEK: AXG53_18865
LCIC: INQ41_12735
LAVI: INQ42_12365
PFN: HZ99_04650
PMUD: NCTC8068_02061(phaJ_1)
PPUU: PputUW4_01806
PFK: PFAS1_01245
PSEJ: HNQ25_04425
PIE: HU724_013970
PSTT: CH92_21350
HPEG: EAO82_03715
THT: E2K93_09365
TPSY: RGQ13_18710
GAG: Glaag_1578
PMES: FX988_04170
PAT: Patl_2716
MICC: AUP74_02898(paaZ)
MAGA: Mag101_09735
MII: BTJ40_11590
MICT: FIU95_07925
MHYD: GTQ55_10130
MVB: MJO52_13465
MPAF: R5R33_01630
HALC: EY643_14920
CBU: CBU_0373
CBS: COXBURSA331_A0480
CBD: CBUD_1709
CBG: CbuG_1636
CBC: CbuK_0564
LLO: LLO_3026
LSH: CAB17_01570
LCJ: NCTC11976_03021
TMC: LMI_0900
FPZ: LA55_828
FNA: OOM_1390
FNL: M973_04670
BMA: BMAA1652
BMV: BMASAVP1_1726
BML: BMA10229_1932
BMN: BMA10247_A0609
BMAL: DM55_3232
BMAE: DM78_4162
BMAQ: DM76_3930
BMAI: DM57_07715
BMAF: DM51_3350
BMAZ: BM44_3168
BMAB: BM45_4007
BPS: BPSS1638
BPM: BURPS1710b_A0702
BPL: BURPS1106A_A2221
BPD: BURPS668_A2304
BPSE: BDL_4991
BPSM: BBQ_4503
BPSU: BBN_5091
BPSD: BBX_4157
BPZ: BP1026B_II1752
BPQ: BPC006_II2199
BPK: BBK_4297
BPSH: DR55_3632
BPSA: BBU_4389
BPSO: X996_5998
BUT: X994_5470
BTD: BTI_4119
BOK: DM82_5766
BOC: BG90_4867
BSAV: WS86_27025
BHG: I6G56_32450
BUD: AQ610_22590
BYI: BYI23_C008040(maoC)
BUE: BRPE67_CCDS03190(maoC)
BUL: BW21_6125
BUM: AXG89_23910 AXG89_28780 AXG89_40395
BUI: AX768_19490
BXE: Bxe_A4088
BXB: DR64_1764
BPY: Bphyt_0612
PARB: CJU94_03205
PTER: C2L65_44455
PACS: FAZ98_15395
PDIO: PDMSB3_0446
PPK: U875_11925
PPNO: DA70_04325
PPNM: LV28_01985
PRB: X636_22780
PTX: ABW99_05285
PAND: DRB87_09750 DRB87_14365
CABA: SBC2_62820(mch)
TVL: FAZ95_35740
BPE: BP0436
BPC: BPTD_0451
BPER: BN118_0287
BPET: B1917_3383
BPEU: Q425_33750
BPAR: BN117_0456
BPA: BPP0463
BBH: BN112_2949
BBR: BB0463
BBM: BN115_0450
BBX: BBS798_0460
BPT: Bpet0844
BHO: D560_0129
BHM: D558_0125
BHZ: ACR54_01121(paaZ_1)
BOH: AKI39_05280
POLL: OEG81_02055
BOZ: DBV39_05635
PARK: LSG25_20015
RFR: Rfer_4170 Rfer_4180
RHF: EUB48_16960
POL: Bpro_5294
CENP: M9799_12210
ADN: Alide_3398
ADK: Alide2_1037
HYR: BSY239_2753
HPSE: HPF_13035(paaZ2)
MNR: ACZ75_13500 ACZ75_18265
XYK: GT347_03980
APET: ToN1_12320
BEB: AEM42_06475
RLS: HB780_13270
VGO: GJW-30_1_01517(paaZ_1)
XDI: EZH22_28925
STAR: G3545_21885
SNO: Snov_3518
BID: Bind_2533
RHZ: RHPLAN_27280
CMET: K6K41_24180(ripB)
RBM: TEF_02360
PHR: C6569_20835
ACUT: MRB58_13920
CSE: Cseg_2763
CFH: C1707_19790
SPSE: SULPSESMR1_04108(mch)
HNE: HNE_1098
HBC: AEM38_15990
NGF: FRF71_11070
NOG: GKE62_07625
SPHM: G432_00490
SPHI: TS85_14845
SLAN: GV829_06060
SAER: NEF64_09100
SRAD: LLW23_07945
SABI: PBT88_13995
SFLA: SPHFLASMR4Y_02130(mch)
SPHY: CHN51_04325
SPHL: LPB140_01050
BLAS: BSY18_2912 BSY18_3093
BFW: B5J99_05640 B5J99_06505
PALG: HFP57_14280
PARP: HFP51_13365
PARJ: J4G78_13065
PHAO: HF685_09495
SMIC: SmB9_17900
SFLV: IC614_07675
SAND: H3309_06830
ALH: G6N82_04765
ANH: A6F65_00044(paaZ_1)
ADO: A6F68_02606(paaZ_3)
EGN: BMF35_a1281
ELQ: Ga0102493_11612
ERYT: KDC96_11235
PHZ: CHX26_06045
PORC: CBR61_08750
SHUM: STHU_28440
SVC: STVA_32330
STEL: STAQ_25590
ABS: AZOBR_p460036
ABQ: ABAZ39_31965
ABF: AMK58_24905 AMK58_27770
AZT: TSH58p_20920
AARE: D3093_28145
NCB: C0V82_13805 C0V82_17290
HADH: FRZ61_45880
THAR: T8K17_02695
TMO: TMO_b0388
GEB: GM18_3660
GER: KP004_02745
GSUB: KP001_12705
GNT: KP003_02380
GPL: M1B72_18220
MSD: MYSTI_02518 MYSTI_04298
MYM: A176_004230
MFB: MFUL124B02_13435 MFUL124B02_23085
MYX: QEG98_21665
MLAN: JY572_05235 JY572_13775
MFU: LILAB_26410
MMAS: MYMAC_003593
PPAK: JY651_16010
AGE: AA314_08469
PARH: I5S86_16400
OON: NP440_17390
ASED: IRT44_09900
HNZ: P9989_10925
HSHI: MUO14_08130
LEX: Len3610_00575
RUE: DT065_03735
SALE: EPH95_03505
SCIB: HUG20_10875
SCIA: HUG15_13410
AHAL: FTX54_001420
BCOP: JD108_17245
BAYD: BSPP4475_15625
ANEU: PP175_10760
SIV: SSIL_0090
SSIL: SOLI23_18375
MTUY: H3143_01770
MSY: MS53_0536
MSO: VY93_02915
MGA: MGA_1305(maoC)
MGH: MGAH_1305
MGF: MGF_3286
MIW: EER00_03360
ERZ: ER308_17470
MLP: MLM_2703
MUL: MUL_4022
MMI: MMAR_4159
MMAE: MMARE11_39690
MLI: MULP_04327
MPSE: MPSD_17120
MSHO: MSHO_16380
MSAK: MSAS_14220
MBAI: MB901379_00390(phaJ)
MSEO: MSEO_43210
MLJ: MLAC_39600
MGO: AFA91_09670
MSTE: MSTE_02642
CPU: CPFRC_05850
CPL: Cp3995_1184
CPG: CP316_06000
CPP: CpP54B96_1180
CPK: CP1002_07295
CPQ: CPC231_05855
CPX: CPI19_05665
CPZ: CpPAT10_1157
COR: Cp267_1212
COP: CP31_06230
COD: Cp106_1142
COS: Cp4202_1151
COI: CPCIP5297_06015
COE: CP258_06010
COU: CP162_05280
CPSE: CPTA_01733
CPSU: CPTB_02030
CPSF: CPTC_01724
CMD: B841_00430
CAQU: CAQU_08895
COK: COCCU_01040
CFAC: CFAEC_04130(paaZ2)
NNO: NONO_c35120
NOZ: DMB37_03985
NIE: KV110_07705 KV110_22130
ROA: Pd630_LPD07625
RPY: Y013_25540
RHB: NY08_70
RHU: A3Q40_00682(mch_1)
RGOR: NMQ04_21480
RHOO: RA302_03040
RFA: A3L23_03454(mch)
RHS: A3Q41_04802(mch)
WHR: OG579_10055
GTA: BCM27_00330
GRU: GCWB2_00255
GAV: C5O27_04375
GOD: GKZ92_00500
GOS: QAD21_00290
GOJ: GR168_00330
GHN: MVF96_00300
GAMI: IHQ52_03920
SRT: Srot_1098
SCO: SCP1.303(sapE)
SGR: SGR_558
SANL: KZO11_35880
SRC: M271_49660
SBH: SBI_09088
STRM: M444_14895
SCAD: DN051_00530 DN051_40280
SNW: BBN63_32945
SRJ: SRO_1328
STIR: DDW44_01555
SFIC: EIZ62_01245
SSPO: DDQ41_10335
SGF: HEP81_01295
SBAT: G4Z16_30040
SVD: CP969_00525
SMOB: J7W19_01990
SMAO: CAG99_00030
SXT: KPP03845_200131(mch)
STUD: STRTU_001462
SGK: PET44_13710
SFIY: F0344_13485
SLUO: PS467_39505
SRPA: HEP86_02135
KSK: KSE_23690
KAB: B7C62_13320
KAU: B6264_30520
KIT: CFP65_5905
STRI: C7M71_005355
MSUW: GCM10025863_19200
AMIN: AUMI_115630
AUW: AURUGA1_01431(paaZ)
SUBA: LQ955_13915 LQ955_17435
ARTP: E5206_12360
ARTY: AHiyo4_01850
POK: SMD14_09280
BSPO: L1F31_01260
NCA: Noca_4064
NOI: FCL41_07655
NFC: KG111_04935
ADB: NP095_13810
AWN: NQV15_15565
MUZ: H4N58_19260
AMAZ: LUW76_46480
ACIR: OG979_01530
SPIQ: OHA34_28675
ACTQ: OG417_30485 OG417_33635
SRO: Sros_6336
NOA: BKM31_26125
NGN: LCN96_20470
NFS: OIE67_25980
MHAI: OHB01_26640 OHB01_36725
FAL: FRAAL3417
SEN: SACE_2330
AMYC: CU254_42145
AORI: SD37_10620
AACD: LWP59_16160 LWP59_38895
ARHD: VSH64_05575
AMOG: QRX60_45590
ACOR: LCL61_28770
PDX: Psed_0099 Psed_4113 Psed_6732
PSEE: FRP1_16985
PSEQ: AD006_24435
PECQ: AD017_04025
PHH: AFB00_22120
PAUT: Pdca_22270
PPEL: H6H00_21480
ACTY: OG774_11915
STP: Strop_0462 Strop_1721
SAQ: Sare_2919
MICH: FJK98_21010
MCRA: ID554_06815
VER: HUT12_06145
MFEU: H1D33_27590
MCAY: PVK37_26025
AMS: AMIS_57130
ACTL: L3i22_079410
ASIC: Q0Z83_062770(ripB)
ACTE: ACTI_81670
PLK: CIK06_24305
PRY: Prubr_51730
DFU: Dfulv_32600 Dfulv_34310
DROS: Drose_23805
DACT: KZZ52_46990
RXY: Rxyl_0670 Rxyl_2737
RRD: RradSPS_1705
RUB: GBA63_03935
BSOL: FSW04_07165
SBAE: DSM104329_05572(mch_2)
LEPV: J4558_03705
CALL: OZ401_004534
PBF: CFX0092_B0383
STI: Sthe_1792
DTAE: LAJ19_17235
VAB: WPS_02220
TPSC: RBB77_12700(ripB)
ARAC: E0W69_008615
HAL: VNG_2290G(maoC1)
HSL: OE_4209F(maoC1)
HANR: LJ422_09245
HAGS: JT689_10595
HABO: JRZ79_08970
HSU: HLASF_0426
HSF: HLASA_0424
HAHS: HSRCO_0071(maoC)
SALR: FQU85_08755
HJE: HacjB3_13725
HALX: M0R89_21420
HAYC: NGM10_17940
NPH: NP_0916A(maoC4)
NHO: HWV23_12055
NSAL: HWV07_13725
HALI: BV210_16875
SSAI: N0B31_11010
HAQ: DU484_05285
HAJ: DU500_05725
HRA: EI982_05240
HALB: EKH57_10330
HALQ: Hrr1229_005595
HSAI: HPS36_05590
SRUB: C2R22_10080
HALG: HUG10_11570
HALU: HUG12_00295 HUG12_04285
HMP: K6T50_17560
HRE: K6T36_16465
HAH: Halar_0325
NMG: Nmag_3455
NPE: Natpe_1337
NVR: FEJ81_07125
NAY: HYG81_23810
HJT: DVR14_15860
NGE: Natgr_2181
HALV: NGM15_18110
NOU: Natoc_4274
NBG: DV706_20325 DV706_21415
NAS: GCU68_04235 GCU68_20760
HDA: BB347_13355
 » show all
Reference
PMID:24657929
  Authors
Sasikaran J, Ziemski M, Zadora PK, Fleig A, Berg IA
  Title
Bacterial itaconate degradation promotes pathogenicity.
  Journal
Nat Chem Biol 10:371-7 (2014)
DOI:10.1038/nchembio.1482
  Sequence
[ypk:y2384]

  All links  
Ontology (4)   
   KEGG BRITE (2)   
   GO (1)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (3628)   
   KEGG GENES (501)   
   KEGG MGENES (3118)   
   RefGene (5)   
   OC (4)   
Literature (1)   
   PubMed (1)   
All databases (3640)   

Download RDF
KEGG   ORTHOLOGY: K18291
Entry
K18291                      KO                                     
Symbol
ich-P
Name
itaconyl-CoA hydratase / mesaconyl-C4 CoA hydratase [EC:4.2.1.56 4.2.1.-]
Pathway
map00660  C5-Branched dibasic acid metabolism
map01100  Metabolic pathways
Reaction
R02491  (3S)-citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    K18291  ich-P; itaconyl-CoA hydratase / mesaconyl-C4 CoA hydratase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.56  itaconyl-CoA hydratase
     K18291  ich-P; itaconyl-CoA hydratase / mesaconyl-C4 CoA hydratase
Other DBs
COG: COG3777
GO: 0050011
Genes
MSEP: CEP49_03360
PAE: PA0878
PAEV: N297_906
PAEI: N296_906
PAU: PA14_52910
PAP: PSPA7_4636
PAG: PLES_44381
PAF: PAM18_4161
PNC: NCGM2_1656
PAEB: NCGM1900_1844
PDK: PADK2_21310
PSG: G655_20960
PRP: M062_04280
PAEP: PA1S_22050
PAER: PA1R_gp4401
PAEM: U769_21420
PAEL: T223_22685
PAES: SCV20265_4646
PAEU: BN889_00914
PAEG: AI22_11890
PAEC: M802_902
PAEO: M801_906
SECH: B18_16040
PMK: MDS_3407
PPSE: BN5_1312
PCQ: PcP3B5_31060
PMUI: G4G71_15745
PNT: G5B91_16300
PPAA: B7D75_20880
PPW: PputW619_3045
PPI: YSA_10993
PPUN: PP4_26620
PFV: Psefu_2660
PSB: Psyr_2172
PFL: PFL_2647
PPRC: PFLCHA0_c27140
PPRO: PPC_2696
PFS: PFLU_3476
PFC: PflA506_2552
PFB: VO64_0589
PVR: PverR02_17225
PAZO: AYR47_23830
PRX: HRH33_17880
PKR: AYO71_15475
PMUD: NCTC8068_02066 NCTC8068_02528 NCTC8068_02749
PTOL: I7845_12940
PMAB: U0037_17380
PFW: PF1751_v1c29070
PFF: PFLUOLIPICF721650
PFX: A7318_12055
PLUL: FOB45_02105 FOB45_04025
PPUU: PputUW4_03342
PDR: H681_12245
PSK: U771_18565
PKC: PKB_4382
PCH: EY04_12145
PCZ: PCL1606_35370
PCP: JM49_17725
PCHP: C4K32_2597
PPV: NJ69_15120
PSES: PSCI_4464
PSEM: TO66_12940
PSIL: PMA3_18295
PYM: AK972_2536
PALL: UYA_16465
PGG: FX982_03217
PPSH: G5J76_13785
PSEJ: HNQ25_09075
PVK: EPZ47_18745
PKH: JLK41_17685
PTY: JWV26_02665
PMAO: PMYSY11_1933(meh)
PVW: HU752_018375
PSAM: HU731_001135
PPRG: HU725_012640
PFAK: KSS94_12290
PIE: HU724_013990
PTAE: NCTC10697_01934
PCAV: D3880_17735
PPHN: HU825_16730
PIZ: LAB08_R18810
PPEG: KUA23_16525
PKM: PZ739_14550
PKK: QQ992_14630
PCHE: QYM18_00115
PTRL: OU419_14950
PPAE: LDL65_26655
PSJY: AA098_14865
PSKU: KUIN1_21650
PSLP: BHQ29_06545
PSNC: C0058_17855
PSA: PST_1693
PSZ: PSTAB_1603
PSR: PSTAA_1723
PSC: A458_12240
PSJ: PSJM300_06605
PSH: Psest_2670
PSTT: CH92_08205
PSTU: UIB01_13505
PSED: DM292_11100
PCHL: LLJ08_12810
PBM: CL52_10795
PKG: LW136_09765
SDEG: GOM96_03895
PDEN: F1C79_09290
PBAU: OS670_05775
MARI: ACP86_19600
MANP: EHN06_02685
OSG: BST96_16095
HBH: E4T21_16530
HAAH: HALA3H3_250007
SAJS: QO259_05865
ADI: B5T_02018
AXE: P40_09650
APAC: S7S_06600
PTES: JQU52_08485
PLG: NCTC10937_02755
BPAR: BN117_1032
BPA: BPP3645
BBH: BN112_4323
BBR: BB4080
BBM: BN115_3769
BBX: BBS798_3873
BPT: Bpet0818
BAV: BAV0713
BHO: D560_1020
BHM: D558_1006
BHZ: ACR54_03835
BTRM: SAMEA390648700436
BPDZ: BBN53_03945
BGM: CAL15_19455
AXY: AXYL_00899
AXO: NH44784_012421
AXN: AX27061_0915
AXX: ERS451415_00902
ADT: APT56_04800
AIS: BUW96_21195
ASW: CVS48_01860
ACHR: C2U31_09190
ACHB: DVB37_03995
ADY: HLG70_17360
ACHO: H4P35_04015
AMUI: PE062_01015
APES: FOC84_07880
AAEG: RA224_27845
ASEL: RAS12_17565
TEQ: TEQUI_0591
TEA: KUI_1574
TEG: KUK_0905
TAS: TASI_1545
TAT: KUM_1150
PUT: PT7_0055
PUS: CKA81_09520
POLL: OEG81_04175
AKA: TKWG_24830
AMIM: MIM_c40140
AALN: Q3V95_01770
BOZ: DBV39_17790
ODH: DHf2319_10955
OUR: CEQ07_11010
OUE: I6G29_06915
PIG: EGT29_18075
PARK: LSG25_07870
BAPI: BBC0122_004680
BAPA: BBC0178_004650
SALO: EF888_16620
CCC: G157_06430
CCQ: N149_0440
CCF: YSQ_07650
CCY: YSS_02005
CCOI: YSU_06660
CCOF: VC76_02320
CCOO: ATE51_03328
PARH: I5S86_16845
SRC: M271_41105
SBH: SBI_00757
SFK: KY5_1011c
SKA: CP970_37850
PEI: H9L10_10385
ACIJ: JS278_00425(meh)
PMAD: BAY61_15180
EKE: EK0264_19105
ABAS: ACPOL_0784
 » show all
Reference
PMID:24657929
  Authors
Sasikaran J, Ziemski M, Zadora PK, Fleig A, Berg IA
  Title
Bacterial itaconate degradation promotes pathogenicity.
  Journal
Nat Chem Biol 10:371-7 (2014)
DOI:10.1038/nchembio.1482
  Sequence
[pae:PA0878]

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