KEGG   ORTHOLOGY: K18337
Entry
K18337                      KO                                     

Name
LRA1
Definition
L-rhamnose 1-dehydrogenase [EC:1.1.1.378 1.1.1.377 1.1.1.173]
Pathway
ko00051  Fructose and mannose metabolism
ko01100  Metabolic pathways
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K18337  LRA1; L-rhamnose 1-dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.173  L-rhamnose 1-dehydrogenase
     K18337  LRA1; L-rhamnose 1-dehydrogenase
    1.1.1.377  L-rhamnose 1-dehydrogenase (NADP+)
     K18337  LRA1; L-rhamnose 1-dehydrogenase
    1.1.1.378  L-rhamnose 1-dehydrogenase [NAD(P)+]
     K18337  LRA1; L-rhamnose 1-dehydrogenase
Other DBs
RN: R03942 R10788 R10995
COG: COG1028
GO: 0050034
Genes
MJV: 108388887
QSU: 111990061 112003557 112030403
PPA: PAS_chr4_0338
DHA: DEHA2E01100g
PIC: PICST_50944(DHG2)
PGU: PGUG_03591
CTEN: CANTEDRAFT_113935
CLU: CLUG_02926
CLUS: A9F13_18g00385
CAUR: CJI97_002171
SLB: AWJ20_4952(SPS19)
NCR: NCU09035
NTE: NEUTE1DRAFT102514(NEUTE1DRAFT_102514)
MGR: MGG_08318
SSCK: SPSK_02647
MAJ: MAA_08254
CMT: CCM_06363
MBE: MBM_02654
ANG: ANI_1_132114(An13g00930) ANI_1_256044(An05g02050)
ABE: ARB_00929
TVE: TRV_00758
PNO: SNOG_14192(SNOG_14191)
PTE: PTT_09742
CNE: CNB05760
CNB: CNBB0030
TASA: A1Q1_01844
ABP: AGABI1DRAFT31987(AGABI1DRAFT_31987)
ABV: AGABI2DRAFT182285(AGABI2DRAFT_182285)
HEL: HELO_4213(rhaD)
SALN: SALB1_2836
AMAH: DLM_0709
BCN: Bcen_6402
BAM: Bamb_3400
BSEM: WJ12_16075
BGP: BGL_2c06950(fabG4)
BXE: Bxe_B1031
BXB: DR64_6352
BPH: Bphy_3467
BFN: OI25_6825
PPUL: RO07_24905
CABA: SBC2_60260
SMI: BN406_03597(fabG1)
SMER: DU99_18905
SMD: Smed_5223(fabG)
PTP: RCA23_c23450(fabG4)
HBA: Hbal_2755
SPHI: TS85_02230
SSAN: NX02_22785
SPHR: BSY17_3168
BLAS: BSY18_1707
PBK: Back11_16610(fabG_2)
ROP: ROP_46140
PAUT: Pdca_50300(fabG_11)
SACI: Sinac_3785
TAC: Ta0747
TVO: TVG0436799(TVG0436799)
AG: EAT09360(LRA1)
 » show all
Reference
  Authors
Watanabe S, Saimura M, Makino K
  Title
Eukaryotic and bacterial gene clusters related to an alternative pathway of nonphosphorylated L-rhamnose metabolism.
  Journal
J Biol Chem 283:20372-82 (2008)
DOI:10.1074/jbc.M801065200
  Sequence

KEGG   ENZYME: 1.1.1.377
Entry
EC 1.1.1.377                Enzyme                                 

Name
L-rhamnose 1-dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
L-rhamnose:NADP+ 1-oxidoreductase
Reaction(IUBMB)
L-rhamnose + NADP+ = L-rhamnono-1,4-lactone + NADPH + H+ [RN:R10788]
Reaction(KEGG)
R10788
Substrate
L-rhamnose [CPD:C00507];
NADP+ [CPD:C00006]
Product
L-rhamnono-1,4-lactone [CPD:C02991];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
The enzyme from the archaeon Thermoplasma acidophilum is part of the non-phosphorylative degradation pathway for L-rhamnose. The enzyme differs in cofactor specificity from EC 1.1.1.173, L-rhamnose 1-dehydrogenase, which is specific for NAD+.
History
EC 1.1.1.377 created 2014
Pathway
ec00051  Fructose and mannose metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K18337  L-rhamnose 1-dehydrogenase
Genes
MJV: 108388887
QSU: 111990061 112003557 112030403
PPA: PAS_chr4_0338
DHA: DEHA2E01100g
PIC: PICST_50944(DHG2)
PGU: PGUG_03591
CTEN: CANTEDRAFT_113935
CLU: CLUG_02926
CLUS: A9F13_18g00385
CAUR: CJI97_002171
SLB: AWJ20_4952(SPS19)
NCR: NCU09035
NTE: NEUTE1DRAFT102514(NEUTE1DRAFT_102514)
MGR: MGG_08318
SSCK: SPSK_02647
MAJ: MAA_08254
CMT: CCM_06363
MBE: MBM_02654
ANG: ANI_1_132114(An13g00930) ANI_1_256044(An05g02050)
ABE: ARB_00929
TVE: TRV_00758
PNO: SNOG_14192(SNOG_14191)
PTE: PTT_09742
CNE: CNB05760
CNB: CNBB0030
TASA: A1Q1_01844
ABP: AGABI1DRAFT31987(AGABI1DRAFT_31987)
ABV: AGABI2DRAFT182285(AGABI2DRAFT_182285)
HEL: HELO_4213(rhaD)
SALN: SALB1_2836
AMAH: DLM_0709
BCN: Bcen_6402
BAM: Bamb_3400
BSEM: WJ12_16075
BGP: BGL_2c06950(fabG4)
BXE: Bxe_B1031
BXB: DR64_6352
BPH: Bphy_3467
BFN: OI25_6825
PPUL: RO07_24905
CABA: SBC2_60260
SMI: BN406_03597(fabG1)
SMER: DU99_18905
SMD: Smed_5223(fabG)
PTP: RCA23_c23450(fabG4)
HBA: Hbal_2755
SPHI: TS85_02230
SSAN: NX02_22785
SPHR: BSY17_3168
BLAS: BSY18_1707
PBK: Back11_16610(fabG_2)
ROP: ROP_46140
PAUT: Pdca_50300(fabG_11)
SACI: Sinac_3785
TAC: Ta0747
TVO: TVG0436799(TVG0436799)
 » show all
Reference
1  [PMID:22481639]
  Authors
Kim SM, Paek KH, Lee SB
  Title
Characterization of NADP+-specific L-rhamnose dehydrogenase from the thermoacidophilic Archaeon Thermoplasma acidophilum.
  Journal
Extremophiles 16:447-54 (2012)
DOI:10.1007/s00792-012-0444-1
  Sequence
[tac:Ta0747]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.377
IUBMB Enzyme Nomenclature: 1.1.1.377
ExPASy - ENZYME nomenclature database: 1.1.1.377
BRENDA, the Enzyme Database: 1.1.1.377

KEGG   REACTION: R10788
Entry
R10788                      Reaction                               

Name
L-rhamnose:NADP+ 1-oxidoreductase
Definition
L-Rhamnose + NADP+ <=> L-Rhamnono-1,4-lactone + NADPH + H+
Equation
Reaction class
RC00001  C00005_C00006
RC00161  C00507_C02991
Enzyme
1.1.1.377       1.1.1.378
Pathway
rn00051  Fructose and mannose metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Orthology
K18337  L-rhamnose 1-dehydrogenase [EC:1.1.1.378 1.1.1.377 1.1.1.173]
Other DBs
RHEA: 42671

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