KEGG   ORTHOLOGY: K18345
Entry
K18345                      KO                                     

Name
vanSB, vanS, vanSD
Definition
two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
Pathway
ko01502  Vancomycin resistance
ko02020  Two-component system
Module
M00651  Vancomycin resistance, D-Ala-D-Lac type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
   01504 Antimicrobial resistance genes
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.13  Protein-histidine kinases
    2.7.13.3  histidine kinase
     K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Protein kinases [BR:ko01001]
 Histidine kinases
  OmpR family
   K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Two-component system [BR:ko02022]
 OmpR family
  VanS-VanR (VanB type vancomycin resistance)
   K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Other DBs
COG: COG0642
GO: 0000155
Genes
VFM: VFMJ11_A0245
SULR: B649_03615
ABU: Abu_0093
ABT: ABED_0093
ABL: A7H1H_0096
ASK: EI285_00355
AELL: AELL_0215(phoR)
AAQI: AAQM_0161(phoR)
BCA: BCE_2750
BCR: BCAH187_C0256
BNC: BCN_P242
BTT: HD73_3279
BTHI: BTK_16195
BTG: BTB_c28350(vanSB1)
BTI: BTG_06075
BTW: BF38_4354
BWW: bwei_2411
BMYO: BG05_3401
BMYC: DJ92_3641
LSP: Bsph_2139(vanSB)
LMO: lmo1061
LMOE: BN418_1279
LMOB: BN419_1276
LMOD: LMON_1071
LMOW: AX10_13880
LMOM: IJ09_04985
LMS: LMLG_2326
LWE: lwe1039
ESI: Exig_2178
EAN: Eab7_2025
PPY: PPE_00623
PPM: PPSC2_03520(cseA)
PPO: PPM_0646(cseA)
PPOL: X809_03015
PPOY: RE92_08460
PLV: ERIC2_c37300(resE2)
PRI: PRIO_4966(vanSB)
EFA: EF2298(vanSB)
EFC: EFAU004_02779(vanSB)
EFAU: EFAU085_00731(vanSB)
CAE: SMB_G2469
CAY: CEA_G2448
CPE: CPE1926
CPF: CPF_2181
CPR: CPR_1892
CBO: CBO1967
CBA: CLB_1907
CBH: CLC_1913
CBY: CLM_2185
CBL: CLK_1422
CBB: CLD_2657
CBI: CLJ_B2173
CBN: CbC4_0691
CBT: CLH_2299
CBF: CLI_2034
CBM: CBF_2019
CKL: CKL_2349
CKR: CKR_2069
CPAS: Clopa_3182
CPAT: CLPA_c16260(resE4)
CPAE: CPAST_c16260(resE4)
CSB: CLSA_c27900(resE8) CLSA_c38170(resE14)
CLD: CLSPO_c19700(vanSB)
CTYK: CTK_C13250
HHW: NCTC503_02474(phoR_6)
RUM: CK1_33670
BPB: bpr_I1235
BHU: bhn_I1156
RIX: RO1_22280
RIM: ROI_10080
CCT: CC1_16960
BPRO: PMF13cell1_04633(resE_11) PMF13cell1_04642(baeS_6)
CSCI: HDCHBGLK_02180(resE_6) HDCHBGLK_02664(phoR_5) HDCHBGLK_03043(cssS_2) HDCHBGLK_03524(resE_9)
CSO: CLS_39260
HSD: SD1D_0646
EHL: EHLA_1169
RTO: RTO_22290
ERT: EUR_09970
ERA: ERE_16230
EAC: EAL2_c21080(resE)
PHX: KGNDJEFE_01027(walK_1)
DSY: DSY1076
DHD: Dhaf_2158
DAE: Dtox_2914
CTHM: CFE_0143
BPRS: CK3_04180
CAD: Curi_c23320(srrB) Curi_c24990(ssrB)
MED: MELS_1146
PUF: UFO1_3882
PFT: JBW_00946
MANA: MAMMFC1_02680(phoR_3)
STED: SPTER_10340(rcsC_3)
ABRA: BN85311380
MBJ: KQ51_00310(phoR) KQ51_00587(cssS)
 » show all
Reference
PMID:8631706
  Authors
Evers S, Courvalin P
  Title
Regulation of VanB-type vancomycin resistance gene expression by the VanS(B)-VanR (B) two-component regulatory system in Enterococcus faecalis V583.
  Journal
J Bacteriol 178:1302-9 (1996)
DOI:10.1128/JB.178.5.1302-1309.1996
  Sequence
[efa:EF2298]
Reference
  Authors
Chancey ST, Zahner D, Stephens DS
  Title
Acquired inducible antimicrobial resistance in Gram-positive bacteria.
  Journal
Future Microbiol 7:959-78 (2012)
DOI:10.2217/fmb.12.63

KEGG   ORTHOLOGY: K18350
Entry
K18350                      KO                                     

Name
vanSC, vanSE, vanSG
Definition
two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
Pathway
ko01502  Vancomycin resistance
ko02020  Two-component system
Module
M00652  Vancomycin resistance, D-Ala-D-Ser type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
   01504 Antimicrobial resistance genes
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.13  Protein-histidine kinases
    2.7.13.3  histidine kinase
     K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
Protein kinases [BR:ko01001]
 Histidine kinases
  OmpR family
   K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
Two-component system [BR:ko02022]
 OmpR family
  VanS-VanR (VanE type vancomycin resistance)
   K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Ser type
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
Other DBs
COG: COG0642
GO: 0000155
Genes
SBA: Sulba_2102
SMUL: SMUL_2732
SHAL: SHALO_2464
MGM: Mmc1_2278
BAH: BAMEG_5139
BAI: BAA_5117
BAX: H9401_1775 H9401_4875
BANT: A16_59525
BANR: A16R_51640
BANS: BAPAT_1791 BAPAT_4897
BCX: BCA_3315
BAL: BACI_c48550(vanS2)
BNC: BCN_4767
BCER: BCK_10890
BTL: BALH_2919(vanS)
BTT: HD73_5162
BTHI: BTK_25455
BTM: MC28_4139
BTG: BTB_c50090(vanS5)
BTI: BTG_24550
BTW: BF38_605
BWW: bwei_0032(baeS)
BMYC: DJ92_3638
BHA: BH1809
LSP: Bsph_1858
VPN: A21D_00713(phoR_1)
BLEN: NCTC4824_00558(phoR_3)
BLR: BRLA_c026940(tcrY)
PSAB: PSAB_01310
PSWU: SY83_09605
SANS: DK43_03845
EFL: EF62_2956
EFI: OG1RF_12162(vanS)
EFS: EFS1_2267
EFQ: DR75_1553
EMU: EMQU_0353
MPX: MPD5_1679
CBL: CLK_3435
CBB: CLD_0505
CBE: Cbei_2250
CBZ: Cbs_2250
CKL: CKL_0023(vanS)
CKR: CKR_0015
CLJ: CLJU_c14370(vanS)
CLS: CXIVA_10770(BaeS)
CSB: CLSA_c16340(vanS1)
CACE: CACET_c25490(vanS)
CTYK: CTK_C03410(vanS)
RUM: CK1_25670
OVA: OBV_09530
CCT: CC1_22660
ROB: CK5_22440
BPRO: PMF13cell1_03977(yycG_4)
CPY: Cphy_0964
CSCI: HDCHBGLK_01279(resE_5) HDCHBGLK_01506(walK_1)
BPRL: CL2_03390
HSD: SD1D_0540 SD1D_1436(vanS)
CPRO: CPRO_11590(phoR_2)
EHL: EHLA_2436
CDF: CD630_16250(vanS)
PDC: CDIF630_01802(vanS)
PDF: CD630DERM_16250(vanS)
DSY: DSY3688
DHD: Dhaf_1666
DAE: Dtox_0489
DED: DHBDCA_p1148(vanS)
DEC: DCF50_p1215(vanS)
ELM: ELI_1495
AMIC: Ami3637_07920(vanR)
FMA: FMG_0124
APR: Apre_1834
CAD: Curi_c20130(vanS)
EBM: SG0102_01590(vanS)
ELE: Elen_1630
EYY: EGYY_06620(BaeS) EGYY_14250(BaeS)
AEQ: AEQU_0448
OLS: Olsu_1025
FLN: FLA_0410
 » show all
Reference
  Authors
Hong HJ, Hutchings MI, Buttner MJ
  Title
Vancomycin resistance VanS/VanR two-component systems.
  Journal
Adv Exp Med Biol 631:200-13 (2008)
DOI:10.1007/978-0-387-78885-2_14

KEGG   ORTHOLOGY: K18351
Entry
K18351                      KO                                     

Name
vanSAc
Definition
two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
Pathway
ko01502  Vancomycin resistance
ko02020  Two-component system
Module
M00651  Vancomycin resistance, D-Ala-D-Lac type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
   01504 Antimicrobial resistance genes
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.13  Protein-histidine kinases
    2.7.13.3  histidine kinase
     K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Protein kinases [BR:ko01001]
 Histidine kinases
  OmpR family
   K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Two-component system [BR:ko02022]
 OmpR family
  VanS-VanR (actinomycete type vancomycin resistance)
   K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Other DBs
COG: COG0642
GO: 0000155
Genes
LLU: AKJ09_02402
MESP: C1M53_06630
MGO: AFA91_06345
CGT: cgR_0540
CGS: C624_02775
CGG: C629_02775
CUR: cu0642(tcsS3)
CUA: CU7111_0631(tcsS3)
CII: CIMIT_04710
CUV: CUREI_04465
CGV: CGLAU_04625(cusS)
NFA: NFA_6940
NFR: ERS450000_03417(baeS)
TPR: Tpau_0521
SCO: SCO3589(SCH66.10c)
SGR: SGR_275
SGB: WQO_33205
SBH: SBI_09519
SVE: SVEN_6833
SPRI: SPRI_1962
SLAU: SLA_2438
SFK: KY5_0087
SGE: DWG14_06772(baeS_3)
LXX: Lxx22000(cutS)
MTS: MTES_0052
MOO: BWL13_02831(tcrY_5)
MLV: CVS47_02386(baeS_2)
MOY: CVS54_00403(tcrY_1)
LMOI: VV02_02725
XCE: Xcel_1425
CFI: Celf_1889
MPH: MLP_00340
PSIM: KR76_22005
KFL: Kfla_3624
NDA: Ndas_4943
NAL: B005_0147
STRR: EKD16_24285(phoR)
SRO: Sros_4755
AMYY: YIM_36555(czcS)
PDX: Psed_6412
PAUT: Pdca_06120
AMI: Amir_4513
SESP: BN6_49740
KAL: KALB_1169
AHG: AHOG_17395(tcrY2)
AFS: AFR_19475
CAI: Caci_5789
SNA: Snas_6029
ASLA: NCTC11923_00130(baeS_1)
AVC: NCTC10951_02506(baeS_3)
BBP: BBPR_1463
BBI: BBIF_1409
BBF: BBB_1442(cutS)
 » show all
Reference
  Authors
Hong HJ, Hutchings MI, Neu JM, Wright GD, Paget MS, Buttner MJ
  Title
Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance.
  Journal
Mol Microbiol 52:1107-21 (2004)
DOI:10.1111/j.1365-2958.2004.04032.x
  Sequence
[sco:SCO3589]

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