KEGG   ORTHOLOGY: K18345
Entry
K18345                      KO                                     
Symbol
vanSB, vanS, vanSD
Name
two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
Pathway
map01502  Vancomycin resistance
map02020  Two-component system
Module
M00651  Vancomycin resistance, D-Ala-D-Lac type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
   01504 Antimicrobial resistance genes
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.13  Protein-histidine kinases
    2.7.13.3  histidine kinase
     K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Protein kinases [BR:ko01001]
 Histidine kinases
  OmpR family
   K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Two-component system [BR:ko02022]
 OmpR family
  VanS-VanR (VanB type vancomycin resistance)
   K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type
    K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS
Other DBs
COG: COG0642
GO: 0000155
Genes
SULR: B649_03615
ABU: Abu_0093
ABT: ABED_0093
ABL: A7H1H_0096
ASK: EI285_00355
AELL: AELL_0215(phoR)
AAQI: AAQM_0161(phoR)
TID: Thein_2219
BCA: BCE_2750
BCR: BCAH187_C0256
BCU: BCAH820_3208
BCG: BCG9842_B2562
BNC: BCN_P242
BCEF: BcrFT9_02139 BcrFT9_02453
BCY: Bcer98_0801
BTT: HD73_3279
BTHR: YBT1520_16160
BTHI: BTK_16195
BTC: CT43_CH2707
BTM: MC28_1919 MC28_G290
BTG: BTB_c28350(vanSB1)
BTI: BTG_06075
BTN: BTF1_11130
BTHT: H175_ch2756
BTHU: YBT1518_15025
BTW: BF38_4354
BTHY: AQ980_14790
BWE: BcerKBAB4_2423 BcerKBAB4_5470
BWW: bwei_2411
BMYO: BG05_3401
BTY: Btoyo_0011
BMYC: DJ92_3641
BBY: CY96_12375
BWD: CT694_14540 CT694_30690 CT694_33085
BMOB: MLA2C4_14440
BNT: GSN03_12695 GSN03_27420
BACI: B1NLA3E_07310
BCIR: C2I06_18125
NTX: NQZ71_24925
NIL: L8T27_024555
LSP: Bsph_2139(vanSB)
TAP: GZ22_02820
LAO: AOX59_15305
BMUR: ABE28_009570
PBUT: DTO10_23090
PPSR: I6J18_14735
PERI: RE409_11565
AQT: FN924_15740
PSYH: D0S48_08860
SEDD: ERJ70_02450
LMO: lmo1061
LMN: LM5578_1144
LMY: LM5923_1098
LMT: LMRG_00523
LMOC: LMOSLCC5850_1067
LMOE: BN418_1279
LMOB: BN419_1276
LMOD: LMON_1071
LMOW: AX10_13880
LMOQ: LM6179_01380
LMR: LMR479A_1089
LMOM: IJ09_04985
LMG: LMKG_01861
LMS: LMLG_2326
LMJ: LMOG_00659
LMX: LMOSLCC2372_1075
LMOS: LMOSLCC7179_1042
LMOY: LMOSLCC2479_1074
LWE: lwe1039
LNW: OTR81_08655
ESI: Exig_2178
EAN: Eab7_2025
EXI: A0126_10715
BBE: BBR47_52010
BFM: BP422_21960
BAGR: BA6348_08520
BPAB: PSE45_21670
BREH: HP435_22160
PJD: Pjdr2_3100 Pjdr2_3221
PPY: PPE_00623
PPM: PPSC2_03520(cseA)
PPO: PPM_0646(cseA)
PPOL: X809_03015
PPQ: PPSQR21_006750
PPOY: RE92_08460
PTA: HPL003_10935
PLV: ERIC2_c37300(resE2)
PBD: PBOR_17860
POD: PODO_08905
PAEN: P40081_18280
PAEF: R50345_09330
PAEQ: R50912_16975
PSTE: PSTEL_14390
PAEA: R70723_24325
PAEE: R70331_16125
PAEJ: H70737_08790
PIH: UB51_21665
PRI: PRIO_4966(vanSB)
PSON: JI735_32505
PPEO: ABE82_03275
PBV: AR543_14270
PXL: BS614_29550
PYG: AWM70_21630
PDH: B9T62_04655
PCX: LPB68_01245
PKB: B4V02_21900
PLUT: EI981_11920 EI981_12425 EI981_18440
PALB: EJC50_06800
PBK: Back11_41330
PPRT: ET464_04670
PBAC: HUB98_13025
PRZ: GZH47_12730
PLYC: GXP70_03805
PTRI: KDC22_16115
PTHI: NDS46_15835 NDS46_26035
PMAH: PTQ21_00990
PAMY: P9222_10650
PDY: QJQ58_05955 QJQ58_26075
PSPN: L1F29_13910
PPAB: KET34_29990
PKP: SK3146_00426(phoR_3)
PHEX: L0M14_28280
COHN: KCTCHS21_58700
SPSY: AZE41_21400
VIJ: JNUCC6_15865
LFB: C1X05_00280
TVU: AB849_004785
EFA: EF2298(vanSB)
EFC: EFAU004_02779(vanSB)
EFAU: EFAU085_00731(vanSB)
VFV: K5K99_10450
CAE: SMB_G2469
CAY: CEA_G2448
CPE: CPE1926
CPF: CPF_2181
CPR: CPR_1892
CNO: NT01CX_1514
CBO: CBO1967
CBA: CLB_1907
CBH: CLC_1913
CBY: CLM_2185
CBL: CLK_1422
CBK: CLL_A2532 CLL_A3542
CBB: CLD_2657
CBI: CLJ_B2173
CBN: CbC4_0691
CBT: CLH_2299
CBF: CLI_2034
CBM: CBF_2019
CBJ: H04402_01992
CBE: Cbei_1732 Cbei_2399 Cbei_4102
CBZ: Cbs_1732 Cbs_2399 Cbs_4102
CBEI: LF65_01871 LF65_03133
CKL: CKL_2349
CKR: CKR_2069
CLJ: CLJU_c25090
CCB: Clocel_0110
CLS: CXIVA_02800
CLB: Clo1100_2888
CSR: Cspa_c07430(resE4) Cspa_c27980 Cspa_c41820 Cspa_c43680
CPAS: Clopa_3182
CPAT: CLPA_c16260(resE4)
CPAE: CPAST_c16260(resE4)
CSB: CLSA_c27900(resE8) CLSA_c38170(resE14)
CAH: CAETHG_0577
CLT: CM240_0168 CM240_0452
CBV: U729_1835 U729_2933
CSQ: CSCA_0317 CSCA_0334 CSCA_3631
CLD: CLSPO_c19700(vanSB)
CCK: Ccar_09990 Ccar_12895 Ccar_12970 Ccar_23185
CBUT: ATN24_08045 ATN24_17885
CTYK: CTK_C13250
CEU: A7L45_11235
CTAE: BGI42_10010 BGI42_14325
CFM: BJL90_12365
CCHV: BTM20_08675
CARG: RSJ17_02905
CDRK: B9W14_01540 B9W14_16810 B9W14_16880
CIA: BEN51_03585
CSEP: CP523_14385
CDY: F3K33_08565 F3K33_12270
CFER: D4Z93_08240
CGAS: J1C67_10030 J1C67_10580 J1C67_14055
CLOS: DMR38_12970
CCAA: KQH81_09145
CMAH: C1I91_09900
CRW: CROST_030750(rcsC_8)
CNN: CNEO_1962
CGEL: psyc5s11_39770
CINT: HZF06_15005
CTHD: CDO33_10300
HHW: NCTC503_02474(phoR_6)
CRS: FQB35_14220
SARJ: HH195_07895
FSA: C5Q98_04880
RUK: A4V00_03270 A4V00_03695 A4V00_17410
RPAY: P0092_16620
FPLA: A4U99_11985
RUM: CK1_33670
OBJ: EIO64_17620
PFAA: MM59RIKEN_16220 MM59RIKEN_25240
LASA: L9O85_08695
PETR: QKW49_05920
AMUR: ADH66_05300 ADH66_05735 ADH66_10890
AGAT: RWV98_07470
INT: RX717_04035
DSY: DSY1076
DHD: Dhaf_2158
DOR: Desor_4980
DED: DHBDCA_p2751
DEC: DCF50_p2761
DRU: Desru_1429
DAE: Dtox_2914
FWA: DCMF_05975
TJR: TherJR_2640
AWO: Awo_c03230
ALKA: J0B03_11950
CTHM: CFE_0143
PROM: QO263_08690
BPRS: CK3_04180
BPB: bpr_I1235
BHU: bhn_I1156
RHO: RHOM_11285 RHOM_13290
RIX: RO1_22280
RIM: ROI_10080
CCT: CC1_16960
CCOM: I6K69_13355
ROB: CK5_20900 CK5_23470
BYL: A4V09_04050 A4V09_04080 A4V09_18600
BHAN: CGC63_09100
BLAU: DQQ01_06315
BPRO: PMF13cell1_04633(resE_11) PMF13cell1_04642(baeS_6)
BLAB: EYS05_10905 EYS05_13415
BLIQ: INP51_03995
BWX: NQ550_08740
BLAR: LC508_08255
BCOC: BLCOC_49320(sasA_43)
BHV: BLHYD_05130(sasA_3)
CPY: Cphy_1288 Cphy_2854
LACY: A4V08_02980 A4V08_06780
CSCI: HDCHBGLK_02180(resE_6) HDCHBGLK_02664(phoR_5) HDCHBGLK_03043(cssS_2) HDCHBGLK_03524(resE_9)
CSH: Closa_3484
CSO: CLS_39260
ARF: AR1Y2_2358
ACAC: EYQ97_06185
HSD: SD1D_0646
LUA: D4A81_06200
EHL: EHLA_1169
PXV: FXF36_12870
ANR: Ana3638_14830 Ana3638_19640
ACEL: acsn021_04840 acsn021_32350
ACHT: bsdcttw_00170
EEL: EUBELI_01176
RTO: RTO_22290
RGN: RGna_01745 RGna_14655
CBOL: CGC65_11040
DLO: K5I24_13160
ERE: EUBREC_1463
ERT: EUR_09970
ERA: ERE_16230
CBAR: PATL70BA_1918
VGU: HYG85_02745
VPY: HZI73_04930 HZI73_19385
ETM: CE91St48_38890
AMT: Amet_1916 Amet_3208
GFE: Gferi_00530 Gferi_24535
PBIF: KXZ80_10410
PSOR: RSJ16_05395 RSJ16_12245
CDF: CD630_21130
PDC: CDIF630_02338
CDC: CD196_1977
CDL: CDR20291_2020
PDF: CD630DERM_21130
ROC: HF520_07225
RIL: CRIB_669
RHOM: FRIFI_0851
PHX: KGNDJEFE_01027(walK_1)
TEM: JW646_17830
TGC: L0P85_10200
TMY: TEMA_08520(rcsC_2)
TPET: TPHSE_23330(rcsC_7)
PEB: O0R46_04870
EAC: EAL2_c21080(resE)
MHAP: JFY71_02820
HKU: HIF96_01285
CAD: Curi_c23320(srrB) Curi_c24990(ssrB)
CAZO: G3A45_11055
MED: MELS_1146
MHW: ACT01_09240
MEG: DKB62_01675
PUF: UFO1_3882
PFT: JBW_00946
MANA: MAMMFC1_02680(phoR_3)
STED: SPTER_10340(rcsC_3)
ERL: AOC36_00700
ERD: G7062_11160
ETT: AZF37_00045
ABRA: BN85311380
MBJ: KQ51_00587(cssS)
TBM: BK010_09695
EGD: GS424_007345
KBS: EPA93_16095
OCK: EXM22_09320
FVA: FV113G1_05290 FV113G1_26050
FUL: C4N20_03660 C4N20_10650
FMO: C4N19_01365 C4N19_06285 C4N19_12595
IPO: Ilyop_0700 Ilyop_1492 Ilyop_2522 Ilyop_2838
STR: Sterm_1085
OCY: OSSY52_19590
MINF: MESINF_0439
 » show all
Reference
PMID:8631706
  Authors
Evers S, Courvalin P
  Title
Regulation of VanB-type vancomycin resistance gene expression by the VanS(B)-VanR (B) two-component regulatory system in Enterococcus faecalis V583.
  Journal
J Bacteriol 178:1302-9 (1996)
DOI:10.1128/JB.178.5.1302-1309.1996
  Sequence
[efa:EF2298]
Reference
PMID:22913355
  Authors
Chancey ST, Zahner D, Stephens DS
  Title
Acquired inducible antimicrobial resistance in Gram-positive bacteria.
  Journal
Future Microbiol 7:959-78 (2012)
DOI:10.2217/fmb.12.63

  All links  
Ontology (7)   
   KEGG BRITE (5)   
   GO (1)   
   COG (1)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (4393)   
   KEGG GENES (376)   
   KEGG MGENES (3786)   
   RefGene (227)   
   OC (4)   
Literature (2)   
   PubMed (2)   
All databases (4408)   

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KEGG   ORTHOLOGY: K18350
Entry
K18350                      KO                                     
Symbol
vanSC, vanSE, vanSG
Name
two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
Pathway
map01502  Vancomycin resistance
map02020  Two-component system
Module
M00652  Vancomycin resistance, D-Ala-D-Ser type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
   01504 Antimicrobial resistance genes
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.13  Protein-histidine kinases
    2.7.13.3  histidine kinase
     K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
Protein kinases [BR:ko01001]
 Histidine kinases
  OmpR family
   K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
Two-component system [BR:ko02022]
 OmpR family
  VanS-VanR (VanE type vancomycin resistance)
   K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Ser type
    K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS
Other DBs
COG: COG0642
GO: 0000155
Genes
BAX: H9401_1775
BANS: BAPAT_1791
BANV: DJ46_687
BCX: BCA_3315
BCF: bcf_15990
BTL: BALH_2919(vanS)
BBY: CY96_28410
GST: HW35_01740
NIL: L8T27_008190
CGOT: J1899_06185
CSOA: LIS82_16525
ASED: IRT44_16980
LSP: Bsph_1858
LFU: HR49_17130
LYS: LBYS11_06520
LYB: C3943_17095
LPAK: GDS87_11030 GDS87_12055(vanS)
LAGR: FJQ98_12680
LMAC: I6G82_11595
LCAP: ICJ70_17720
LIU: OU989_06375
LLB: R6U77_02725
ALKL: MM271_03690
BAYD: BSPP4475_08365(vanS)
PAEQ: R50912_28865
PAEH: H70357_27985
PRI: PRIO_4178 PRIO_5442(vanS)
PSON: JI735_02180(vanR)
PDH: B9T62_36050
PSOP: KP014_14560
PUI: PUW25_20495
PMAE: LMZ02_20985
TVU: AB849_010235
SANS: DK43_03845
EFL: EF62_2956
EFI: OG1RF_12162(vanS)
EFD: EFD32_2463
EFS: EFS1_2267
EFN: DENG_02751
EFQ: DR75_1553
ECAS: ECBG_00725 ECBG_02845
EMU: EMQU_0353
EGA: AL523_09445 AL523_17440
ESG: EsVE80_p1-00060
EIE: ENLAB_03630 ENLAB_26710
ENI: CXM95_04540
MPX: MPD5_1679
VAH: G7081_07190
VCP: H9L18_00470
VHY: G7082_04875
CBL: CLK_3435
CBB: CLD_0505
CBE: Cbei_2250
CBZ: Cbs_2250
CKL: CKL_0023(vanS)
CKR: CKR_0015
CLJ: CLJU_c14370(vanS)
CLS: CXIVA_10770(BaeS)
CLB: Clo1100_2031
CSB: CLSA_c16340(vanS1)
CSQ: CSCA_0367 CSCA_4600
CACE: CACET_c25490(vanS)
CCK: Ccar_18535
CBUT: ATN24_19660
CTYK: CTK_C03410(vanS)
CFM: BJL90_20415
CDRK: B9W14_16655 B9W14_22000
CLOS: DMR38_11325
CINT: HZF06_06795
CTHD: CDO33_12490
CCL: Clocl_3630
RUK: A4V00_07865
RPAY: P0092_11955
FPLA: A4U99_10005 A4U99_16780
RUM: CK1_25670
RGV: NQ502_00385 NQ502_10115 NQ502_15000
FPRA: CG447_08260
OVA: OBV_09530
OBJ: EIO64_13530
CAML: H6X83_02535
SMAN: C12CBH8_13040
PFAA: MM59RIKEN_12780
VCOP: MM50RIKEN_08130(vanS)
CFEM: HCR03_17600 HCR03_19265
AMUR: ADH66_01100
AGAT: RWV98_19105
DSY: DSY3688
DHD: Dhaf_1666
DDH: Desde_1756
DDL: Desdi_1462
DOR: Desor_3888
DMI: Desmer_1787
DED: DHBDCA_p1148(vanS)
DEC: DCF50_p1215(vanS)
DRS: DEHRE_10535
DRU: Desru_0028
DFG: B0537_04805
DAE: Dtox_0489
FWA: DCMF_02645
DGI: Desgi_1737
ELM: ELI_1495
EMT: CPZ25_000845
ELIM: B2M23_14665
IBU: IB211_00346
RHO: RHOM_15550
CCT: CC1_22660
CCOM: I6K69_09030
CEV: LK421_09130
ROB: CK5_22440
BYL: A4V09_06580 A4V09_08710
BHAN: CGC63_07015
BLAU: DQQ01_06720
BPRO: PMF13cell1_03977(yycG_4)
BLAB: EYS05_13165 EYS05_15680
BLIQ: INP51_15875
BWX: NQ550_13035
BLAR: LC508_04510 LC508_18105 LC508_18540
BCOC: BLCOC_29270(sasA_26)
BHV: BLHYD_30310(sasA_15)
CPY: Cphy_0964
LACY: A4V08_03545 A4V08_06420
CSCI: HDCHBGLK_01279(resE_5) HDCHBGLK_01506(walK_1)
CHYL: CE91St63_01160 CE91St63_23730
CSH: Closa_1197 Closa_3166
LXA: OW255_13720 OW255_19410
BPRL: CL2_03390
ARF: AR1Y2_2985
ACAC: EYQ97_03400
HSD: SD1D_0540 SD1D_1436(vanS)
ANR: Ana3638_21370(vanS)
ACEL: acsn021_16950
ACHT: bsdcttw_20160 bsdcttw_22880(vanS)
CASP: NQ535_19580
DLO: K5I24_09370
DFM: NQ560_14420
SINT: K5I26_02875
WCP: H9Q76_11100
QDO: H9Q78_03835
WHJ: H9Q79_00690(vanS) H9Q79_01745
AHB: bsdtb5_30340(vanS)
ERE: EUBREC_3506 EUBREC_3558
KIB: RBB56_07955
CBIL: EUBC25_13780 EUBC25_14900
HHJ: NQ487_24495
CPRO: CPRO_11590(phoR_2)
VGU: HYG85_23285
MDV: C5Q96_06435
AMIC: Ami3637_07920(vanR)
ABUT: Ami103574_02960 Ami103574_07950
ETM: CE91St48_02980(vanS) CE91St48_23350
CDF: CD630_16250(vanS)
PDC: CDIF630_01802(vanS)
CDC: CD196_1548(vanS) CD196_3078
CDL: CDR20291_1523(vanS) CDR20291_3124
PDF: CD630DERM_16250(vanS)
FMA: FMG_0124
APR: Apre_1834
AVG: I6H45_03130
AOB: I6H46_06195
CAD: Curi_c20130(vanS)
SPOA: EQM13_02200
KPAR: JL105_06735 JL105_07650 JL105_07795
TIZ: RBU61_00880
AARG: Aargi30884_11260(vanS) Aargi30884_11270
ABSI: A9CBEGH2_12380(vanS) A9CBEGH2_12390
LCG: L3BBH23_19270(vanS) L3BBH23_22110 L3BBH23_22120
AHQ: NMU03_00560 NMU03_13405
ERB: A4V01_07735 A4V01_07740 A4V01_19665
EHN: H9Q80_05690
CIU: G4D55_06600 G4D55_06605 G4D55_16935
TFC: T23_01440
ERM: EYR00_11430
TSF: NQ543_09465
FBS: N510_001798(sasA_7) N510_002079(sasA_8)
OLS: Olsu_1025
CGO: Corgl_0369
CAER: CSV91_09205
CSTC: LK434_09700
COLL: KPC83_05830
SHI: Shel_05740
ELE: Elen_1630
EYY: EGYY_06620(BaeS) EGYY_14250(BaeS)
EGD: GS424_008385
AEQ: AEQU_0448
AHAT: ADCFC_19500
RTS: CE91St31_17360
BGX: ESN35_05205
BLEM: BL8807_09385
BEU: BE0216_01980
 » show all
Reference
PMID:18792691
  Authors
Hong HJ, Hutchings MI, Buttner MJ
  Title
Vancomycin resistance VanS/VanR two-component systems.
  Journal
Adv Exp Med Biol 631:200-13 (2008)
DOI:10.1007/978-0-387-78885-2_14

  All links  
Ontology (7)   
   KEGG BRITE (5)   
   GO (1)   
   COG (1)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (3150)   
   KEGG GENES (231)   
   KEGG MGENES (2389)   
   RefGene (528)   
   OC (2)   
Literature (1)   
   PubMed (1)   
All databases (3164)   

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KEGG   ORTHOLOGY: K18351
Entry
K18351                      KO                                     
Symbol
vanSAc
Name
two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]
Pathway
map01502  Vancomycin resistance
map02020  Two-component system
Module
M00651  Vancomycin resistance, D-Ala-D-Lac type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
   01504 Antimicrobial resistance genes
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.13  Protein-histidine kinases
    2.7.13.3  histidine kinase
     K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Protein kinases [BR:ko01001]
 Histidine kinases
  OmpR family
   K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Two-component system [BR:ko02022]
 OmpR family
  VanS-VanR (actinomycete type vancomycin resistance)
   K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type
    K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS
Other DBs
COG: COG0642
GO: 0000155
Genes
MESP: C1M53_06630
LLU: AKJ09_02402
MMAT: MMAGJ_17070
MBOK: MBOE_16170
MFG: K6L26_29335
MGO: AFA91_06345
MSEN: K3U95_02375
CGT: cgR_0540
CGS: C624_02775
CGG: C629_02775
CUR: cu0642(tcsS3)
CUA: CU7111_0631(tcsS3)
CII: CIMIT_04710
CUV: CUREI_04465
CSTA: CSTAT_08730
CGV: CGLAU_04625(cusS)
CSTR: CBE89_03740
CLUJ: IAU68_04305
CWK: IA203_04775
CCOY: CCOY_04705(prrB)
CHAD: CHAD_04955(tcrY1)
CAQM: CAQUA_07140(tcrY2)
CFOU: CFOUR_04095(cusS)
CAFE: CAFEL_04015(prrB)
CGOI: CGOTT_04610(tcrY1)
CPYR: CYJ47_11170
CRIE: AK829_05280
NFA: NFA_6940
NFR: ERS450000_03417(baeS)
NBR: O3I_015645
NTP: CRH09_24955 CRH09_30825
NOZ: DMB37_03915
NOD: FOH10_18600
NAH: F5544_23940
NWL: NWFMUON74_26200
NIE: KV110_10645
TPR: Tpau_0521
TOY: FO059_01065
SCO: SCO3589(SCH66.10c)
SGR: SGR_275
SGB: WQO_33205
SANL: KZO11_37250
SRC: M271_02035
SSOI: I1A49_01635
SBH: SBI_09519
SVE: SVEN_6833
SDV: BN159_0591
SLV: SLIV_20350
SVT: SVTN_32450
SXI: SXIM_13630 SXIM_54590
STRC: AA958_28395
SPRI: SPRI_1962
SPAV: Spa2297_16660
SCLF: BB341_22520
SALW: CP975_31545
SGM: GCM10017557_80010
SCAD: DN051_03195
SPHW: NFX46_17035
SLS: SLINC_1092 SLINC_1848
SSIA: A7J05_01450
SVU: B1H20_33820
SLAU: SLA_2438
SALF: SMD44_04674
SFK: KY5_0087
SNZ: DC008_14115
SGE: DWG14_06772(baeS_3)
SCYA: EJ357_46335
SNQ: CP978_27460
SPAD: DVK44_32100
SFY: GFH48_02780
SAQU: EJC51_03765 EJC51_04145
SBY: H7H31_16200
SRIM: CP984_39890
SPHV: F9278_37080
SPAC: B1H29_35910
SCHA: CP983_42260
SGX: H4W23_38845
SCOE: CP976_02300
SBAT: G4Z16_05555
SSPB: CP982_05210 CP982_31345
SATA: C5746_15280
SHUN: DWB77_02451(baeS)
SHAR: HUT13_07520
SFEU: IM697_16505
SCAL: I6J39_33555
SROI: IAG44_39610
SXN: IAG42_06505
SHK: J2N69_01865
SACT: DMT42_35875
SLF: JEQ17_01095 JEQ17_11730
SAOV: G3H79_40170
SDUR: M4V62_41780
SYAN: NRK68_00220
STAA: LDH80_01980
SCAE: IHE65_05525
SSPN: LXH13_01015 LXH13_33520
SCIR: STRCI_007802
SXT: KPP03845_104341(tcrY_3)
SLON: LGI35_00730
SDRZ: NEH16_00885
SARG: HKX69_30385
SCOA: QU709_40325 QU709_45485
SFP: QUY26_18065
STTN: BSL84_01230
SINN: ABB07_36970
STRZ: OYE22_15945
SCAY: PYS65_08925
KBU: Q4V64_46390
SCAJ: O1G22_01815
KIS: HUT16_12475
KCH: O1G21_34300
YIA: LO772_35440
ABRY: NYE86_22050
AGLA: OIE69_40650
LXL: KDY119_02009
PSIC: J4E96_06995 J4E96_09260
LXX: Lxx22000(cutS)
MTS: MTES_0052
MIM: AKG07_14440
MIO: AOA12_11715
MIX: AB663_001133
MIP: AXH82_08270
MPAL: BO218_06375
MIH: BJP65_02470
MICR: BMW26_01495
MFOL: DXT68_01605
MOO: BWL13_02831(tcrY_5)
MLV: CVS47_02386(baeS_2)
MWA: E4K62_07335
MSED: E3O41_07835
MOY: CVS54_00403(tcrY_1)
MCAW: F6J84_08970
MLZ: F6J85_07020
MRN: K8F61_12795
MICS: C1N74_04710
MBIN: LXM64_01835 LXM64_15125
MLIQ: NMQ05_01425
MTEC: OAU46_09580
MPAO: IZR02_01565
MAZA: NFX31_00835
MARK: QUC20_04515
MPLN: VC184_04350
MICE: EHF32_10795 EHF32_13545
MAUG: KV397_15350
MSUF: KV394_06780
RTN: A6122_0296
RRY: C1O28_00065
RIA: C7V51_10870
RTE: GSU10_00910
CUF: KM842_08215
CUY: I8920_03460
MVD: AWU67_07985
FRP: AX769_07725
AGY: ATC03_11875 ATC03_14850
AGF: ET445_10590
ASOI: MTP13_07495
CART: PA27867_3641
CPHY: B5808_17910
MSPO: KXZ72_08800
PLAP: EAO79_01050 EAO79_07970
PFLU: BWO91_16685
LEB: G7066_05545
LVI: G7068_14870
LLUT: K1X41_08205
LARI: KI794_00070
LALL: MUN78_10645
LRP: MUN76_01680
LTN: KVY00_14765
AGG: C1N71_03545
HEH: L3i23_05610
AGX: AGREI_3191
ARE: AL755_06815
AWW: G8758_12115
AKO: N9A08_01400
GAR: AOZ07_13010
GCR: GcLGCM259_2668
MLY: CJ228_005705
AUL: DCC27_010090
AIG: QDX25_10095
BRX: BH708_10785
HMM: R3I40_05140
LMOI: VV02_02725
XCE: Xcel_1425
XYL: ET495_16455
XYA: ET471_12860
SKE: Sked_26830
CFI: Celf_1889
CIRA: LFM56_03725
OEK: FFI11_006460
PHW: G7075_00560
SERW: FY030_05315
OFA: NF556_15810
BLUT: EW640_11540
BCAU: I6G59_17630
HALT: IM660_06620 IM660_06715
RHAL: LQF10_12945 LQF10_13470
RSUA: LQF12_10425
MPH: MLP_00340
MIK: FOE78_00310
MICG: GJV80_21410
TDF: H9L22_00860
NBE: Back2_27460
NARO: CFH99_24335
NBI: SHK19_15350
PSIM: KR76_22005
MUZ: H4N58_14060
SGRG: L0C25_10515
KFL: Kfla_3624
KQI: F1D05_26450
KSL: OG809_06690 OG809_30970 OG809_31040
KRI: OX958_05845
NDA: Ndas_4943
NAL: B005_0147
NFE: HUT17_02590
NEC: KGD82_08720
NAKE: KGD83_27070
NCG: KGD84_02480 KGD84_09275
STRR: EKD16_24285(phoR)
SNAH: OUQ99_08300
ACTW: F7P10_09875
AGRA: AGRA3207_002876 AGRA3207_003206
ACIR: OG979_09870
SPIQ: OHA34_26505
ACTQ: OG417_51660
SRO: Sros_4755
NOW: GBF35_48600
FRE: Franean1_7134
MOM: KUM42_01575
AMD: AMED_8142 AMED_8287
AMN: RAM_41825 RAM_42555
AMM: AMES_8018 AMES_8161
AMZ: B737_8019 B737_8162
AMYC: CU254_05715
AAB: A4R43_21415
AMYY: YIM_36555(czcS)
APRT: MUY14_04900
ATHM: L1857_33125
AMOG: QRX60_03805
ACYN: ORV05_27525
PDX: Psed_6412
PHH: AFB00_19615
PAUT: Pdca_06120
PBRO: HOP40_21925
PSDS: K1T35_18745 K1T35_44620
APRE: CNX65_22455
AMI: Amir_4513
SESP: BN6_49740
SSYI: EKG83_05365
SACX: IOD16_21965
KAL: KALB_1169
KUT: JJ691_70630
KPHY: AOZ06_08695 AOZ06_30195
LED: BBK82_06950
AHM: TL08_02710 TL08_03385
ACTI: UA75_02670 UA75_19685
ACAD: UA74_02665 UA74_19195
AHG: AHOG_17395(tcrY2)
ACTU: Actkin_02320(baeS_1)
CROS: N8J89_03415
UME: RM788_01990
MCAB: HXZ27_24365
MSAG: GCM10017556_02050
MFEU: H1D33_06070
MCAY: PVK37_05380
AMS: AMIS_51750
AIH: Aiant_83680
AOU: ACTOB_006497
AFS: AFR_19475
PSUU: Psuf_008110
ATL: Athai_15790
ASER: Asera_58780
DVC: Dvina_16575 Dvina_26180
DAUR: Daura_13335
DMAT: Dmats_21710
CCAZ: COUCH_31260
CAI: Caci_5789
SNA: Snas_6029
GLY: K3N28_22505
TPEC: HLG82_10055
AOS: AXE84_05780
ARD: AXF14_03435
ACTP: B6G06_00650
ACTO: C3V41_11975
ANE: ATCC27039_25320
ASLA: NCTC11923_00130(baeS_1)
AVC: NCTC10951_02506(baeS_3)
AMAM: HPC72_09420
AREP: ID810_00905
AMAS: QU670_01260
ACAP: MANAM107_07480
AUO: R3I39_04070
BBP: BBPR_1463
BBI: BBIF_1409
BBF: BBB_1442(cutS)
EKE: EK0264_15880
BSOL: FSW04_08040
BALA: DSM104299_02089(cusS)
CWO: Cwoe_0519 Cwoe_1411
SBAE: DSM104329_00640(sasA_1)
IAM: HC251_12740
DHI: LH044_08555
MCAO: IT6_05480
 » show all
Reference
PMID:15130128
  Authors
Hong HJ, Hutchings MI, Neu JM, Wright GD, Paget MS, Buttner MJ
  Title
Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance.
  Journal
Mol Microbiol 52:1107-21 (2004)
DOI:10.1111/j.1365-2958.2004.04032.x
  Sequence
[sco:SCO3589]

  All links  
Ontology (7)   
   KEGG BRITE (5)   
   GO (1)   
   COG (1)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (501)   
   KEGG GENES (332)   
   KEGG MGENES (163)   
   RefGene (2)   
   OC (4)   
Literature (1)   
   PubMed (1)   
All databases (515)   

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