KEGG   ORTHOLOGY: K18347
Entry
K18347                      KO                                     

Name
vanH
Definition
D-specific alpha-keto acid dehydrogenase [EC:1.1.1.-]
Pathway
ko01502  Vancomycin resistance
ko02020  Two-component system
Module
M00651  Vancomycin resistance, D-Ala-D-Lac type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18347  vanH; D-specific alpha-keto acid dehydrogenase
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18347  vanH; D-specific alpha-keto acid dehydrogenase
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   01504 Antimicrobial resistance genes
    K18347  vanH; D-specific alpha-keto acid dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.-  
     K18347  vanH; D-specific alpha-keto acid dehydrogenase
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type
    K18347  vanH; D-specific alpha-keto acid dehydrogenase
Other DBs
COG: COG1052
Genes
PLV: ERIC2_c07970(vanHE)
EFA: EF2295
EFC: EFAU004_02776(vanHB)
EFAU: EFAU085_00734(vanHB)
ESG: EsVE80_p1-00070(vanH)
CARG: RSJ17_20570
AMIC: Ami3637_13560
NTP: CRH09_30845
NWL: NWFMUON74_45690(vanH)
TPR: Tpau_0524
SCO: SCO3594(dldh)
SLV: SLIV_20325(vanH)
SRIM: CP984_39905(vanH)
KFL: Kfla_3619
KQI: F1D05_26430(vanH)
AMD: AMED_8290(vanH)
AMN: RAM_42570
AMM: AMES_8163(vanH)
AMZ: B737_8164(vanH)
AOI: AORI_1471(ldhA)
AJA: AJAP_32175(vanH)
AMYY: YIM_36530(vanH)
AORI: SD37_33765
SESP: BN6_49770(vanH)
KAL: KALB_1173
PSUU: Psuf_054810(vanH)
ATL: Athai_15830(vanH)
CAI: Caci_5794
SNA: Snas_5355
CWO: Cwoe_1413
KBS: EPA93_09970(vanH)
MARC: AR505_1122
 » show all
Reference
PMID:8631706
  Authors
Evers S, Courvalin P
  Title
Regulation of VanB-type vancomycin resistance gene expression by the VanS(B)-VanR (B) two-component regulatory system in Enterococcus faecalis V583.
  Journal
J Bacteriol 178:1302-9 (1996)
DOI:10.1128/JB.178.5.1302-1309.1996
  Sequence
[efa:EF2295]
Reference
  Authors
Chancey ST, Zahner D, Stephens DS
  Title
Acquired inducible antimicrobial resistance in Gram-positive bacteria.
  Journal
Future Microbiol 7:959-78 (2012)
DOI:10.2217/fmb.12.63
Reference
  Authors
Hong HJ, Hutchings MI, Neu JM, Wright GD, Paget MS, Buttner MJ
  Title
Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance.
  Journal
Mol Microbiol 52:1107-21 (2004)
DOI:10.1111/j.1365-2958.2004.04032.x
  Sequence
[sco:SCO3594]

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