KEGG   ORTHOLOGY: K18352
Entry
K18352                      KO                                     
Symbol
vanRAc
Name
two-component system, OmpR family, response regulator VanR
Pathway
map01502  Vancomycin resistance
map02020  Two-component system
Module
M00651  Vancomycin resistance, D-Ala-D-Lac type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18352  vanRAc; two-component system, OmpR family, response regulator VanR
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18352  vanRAc; two-component system, OmpR family, response regulator VanR
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K18352  vanRAc; two-component system, OmpR family, response regulator VanR
   01504 Antimicrobial resistance genes
    K18352  vanRAc; two-component system, OmpR family, response regulator VanR
Two-component system [BR:ko02022]
 OmpR family
  VanS-VanR (actinomycete type vancomycin resistance)
   K18352  vanRAc; two-component system, OmpR family, response regulator VanR
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type
    K18352  vanRAc; two-component system, OmpR family, response regulator VanR
Other DBs
COG: COG0745
GO: 0000156
Genes
MESP: C1M53_06625
LLU: AKJ09_02403
MMAT: MMAGJ_17060
MBOK: MBOE_16180
MFG: K6L26_29330
MGO: AFA91_06350
MSEN: K3U95_02380
NFA: NFA_6930
NFR: ERS450000_03418(cusR)
NBR: O3I_015640
NIE: KV110_10650(vanR-Sc)
TPR: Tpau_0520
SCO: SCO3590(SC66T3.01c)
SGR: SGR_274
SGB: WQO_33210
SBH: SBI_09520
SVE: SVEN_6832
SDV: BN159_0592(cutR3)
SPRI: SPRI_1963
SLX: SLAV_20195(copR2)
SFK: KY5_0097
SGE: DWG14_06771(czcR)
SHUN: DWB77_02450(tcrA_2)
SXT: KPP03845_104342(tcrA_2)
LXL: KDY119_02010(rcsC)
LXX: Lxx22010(cutR)
MTS: MTES_0051
MOO: BWL13_02830(copR_2)
MLV: CVS47_02385(mprA)
MOY: CVS54_00404(tcrA_1)
AGX: AGREI_3192(cutR)
LMOI: VV02_02720
XCE: Xcel_1424
CFI: Celf_1890
MPH: MLP_00360
PSIM: KR76_22010
KFL: Kfla_3625
NDA: Ndas_4944
NAL: B005_0148
STRR: EKD16_24290(tcrA2)
SRO: Sros_4756
AMD: AMED_8286
AMN: RAM_42550
AMM: AMES_8159
AMZ: B737_8160
AMYY: YIM_20800(mprA2) YIM_36560(cusR)
AMOG: QRX60_03810(vanR-Sc)
PDX: Psed_6411
PAUT: Pdca_06130
AMI: Amir_4514
SESP: BN6_49710
KAL: KALB_1168
AHG: AHOG_17400(czcR)
ACTU: Actkin_02319(tcrA_2)
AFS: AFR_19470
CAI: Caci_5788
SNA: Snas_6028
TPYO: X956_00310
AVC: NCTC10951_02507(tcrA)
BALA: DSM104299_02090(tcrA)
SBAE: DSM104329_00641(copR)
 » show all
Reference
  Authors
Hong HJ, Hutchings MI, Neu JM, Wright GD, Paget MS, Buttner MJ
  Title
Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance.
  Journal
Mol Microbiol 52:1107-21 (2004)
DOI:10.1111/j.1365-2958.2004.04032.x
  Sequence
[sco:SCO3590]

KEGG   ORTHOLOGY: K18344
Entry
K18344                      KO                                     
Symbol
vanRB, vanR, vanRD
Name
two-component system, OmpR family, response regulator VanR
Pathway
map01502  Vancomycin resistance
map02020  Two-component system
Module
M00651  Vancomycin resistance, D-Ala-D-Lac type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18344  vanRB, vanR, vanRD; two-component system, OmpR family, response regulator VanR
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18344  vanRB, vanR, vanRD; two-component system, OmpR family, response regulator VanR
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K18344  vanRB, vanR, vanRD; two-component system, OmpR family, response regulator VanR
   01504 Antimicrobial resistance genes
    K18344  vanRB, vanR, vanRD; two-component system, OmpR family, response regulator VanR
Two-component system [BR:ko02022]
 OmpR family
  VanS-VanR (VanB type vancomycin resistance)
   K18344  vanRB, vanR, vanRD; two-component system, OmpR family, response regulator VanR
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Lac type
    K18344  vanRB, vanR, vanRD; two-component system, OmpR family, response regulator VanR
Other DBs
COG: COG0745 COG0784
GO: 0000156
Genes
REV: HUE57_13945
SKU: Sulku_1910
CCV: CCV52592_1547
CCO: CCC13826_0005
CCOL: BN865_06520
CCC: G157_01425
CCQ: N149_1440
CCY: YSS_07960
CCOI: YSU_01460
CCOF: VC76_07370(mprA_2)
CCOO: ATE51_00586(mprA_1)
CHYO: CHH_0759
CSPF: CSF_0470
CGEO: CGEO_0975
CBLA: CBLAS_1801
ATP: ATR_0029
ACIB: ACBT_0073
ACRE: ACRYA_1972
APOC: APORC_1175
AMOL: AMOL_1716
NIS: NIS_1288
DMA: DMR_36550
BMX: BMS_0403
BAN: BA_5275
BAR: GBAA_5275
BAT: BAS4900
BAI: BAA_5306
BANT: A16_52910
BANR: A16R_53530
BANS: BAPAT_5058
BANV: DJ46_3946
BCE: BC5028
BCA: BCE_2749(OmpR2) BCE_5173
BCQ: BCQ_4853
BCX: BCA_5181
BNC: BCN_4940
BCF: bcf_25265
BCER: BCK_10095
BTL: BALH_4570
BTG: BTB_c28340(vanRB) BTB_c52570
BWW: bwei_2410 bwei_4734(vanRB)
BMYC: DJ92_3642
LSP: Bsph_2138(ompR2) Bsph_2819(vanRB)
LMO: lmo1060
LMOE: BN418_1278
LMOB: BN419_1275
LMOD: LMON_1070
LMOW: AX10_13875
LMR: LMR479A_1088(vanRB)
LMOM: IJ09_04990
LMS: LMLG_2327
LWE: lwe1038
ESI: Exig_2177
EAN: Eab7_2024
GMO: NCTC11323_00822(walR_1)
PRI: PRIO_4967(vanRB)
PKP: SK3146_00427(phoP_1)
EFA: EF2299(vanRB)
EFL: EF62_2230
EFQ: DR75_834
EFC: EFAU004_02780(vanRB)
EFU: HMPREF0351_12984(vncR)
EIE: ENLAB_20200(ompR_13)
CBO: CBO1968
CBA: CLB_1908
CBH: CLC_1914
CBY: CLM_2186
CBL: CLK_1423
CBB: CLD_2656
CBI: CLJ_B2174
CBF: CLI_2035
CBM: CBF_2020
CLT: CM240_0451(vanRB)
CBV: U729_1834
CLD: CLSPO_c19710(vanRB)
BCOC: BLCOC_49330(walR_6)
CPY: Cphy_1287
CSCI: HDCHBGLK_02663(cseB)
CSO: CLS_07200
CPRO: CPRO_09770(rcsC)
RIL: CRIB_668
PHX: KGNDJEFE_01026(regX3_2)
TMY: TEMA_08510(regX3_3)
FMA: FMG_0132
ERH: ERH_1429
ABRA: BN85311370
CABY: Cabys_978
 » show all
Reference
PMID:8631706
  Authors
Evers S, Courvalin P
  Title
Regulation of VanB-type vancomycin resistance gene expression by the VanS(B)-VanR (B) two-component regulatory system in Enterococcus faecalis V583.
  Journal
J Bacteriol 178:1302-9 (1996)
DOI:10.1128/JB.178.5.1302-1309.1996
  Sequence
[efa:EF2299]
Reference
  Authors
Chancey ST, Zahner D, Stephens DS
  Title
Acquired inducible antimicrobial resistance in Gram-positive bacteria.
  Journal
Future Microbiol 7:959-78 (2012)
DOI:10.2217/fmb.12.63

KEGG   ORTHOLOGY: K18349
Entry
K18349                      KO                                     
Symbol
vanRC, vanRE, vanRG
Name
two-component system, OmpR family, response regulator VanR
Pathway
map01502  Vancomycin resistance
map02020  Two-component system
Module
M00652  Vancomycin resistance, D-Ala-D-Ser type
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K18349  vanRC, vanRE, vanRG; two-component system, OmpR family, response regulator VanR
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    K18349  vanRC, vanRE, vanRG; two-component system, OmpR family, response regulator VanR
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K18349  vanRC, vanRE, vanRG; two-component system, OmpR family, response regulator VanR
   01504 Antimicrobial resistance genes
    K18349  vanRC, vanRE, vanRG; two-component system, OmpR family, response regulator VanR
Two-component system [BR:ko02022]
 OmpR family
  VanS-VanR (VanE type vancomycin resistance)
   K18349  vanRC, vanRE, vanRG; two-component system, OmpR family, response regulator VanR
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  Vancomycin resistance modules
   Vancomycin resistance, D-Ala-D-Ser type
    K18349  vanRC, vanRE, vanRG; two-component system, OmpR family, response regulator VanR
Other DBs
COG: COG0745
GO: 0000156
Genes
BCR: BCAH187_A1985
BCQ: BCQ_1871
BCX: BCA_3316
BNC: BCN_1798
BCF: bcf_15995
BCER: BCK_25235
BCEF: BcrFT9_01541
BTL: BALH_2920(vanR)
BBY: CY96_28405
BMOB: MLA2C4_09555
NTX: NQZ71_21010(vanR)
NIL: L8T27_008185(vanR)
CGOT: J1899_06190(vanR)
CSOA: LIS82_16520(vanR)
ASED: IRT44_16985(vanR)
LSP: Bsph_1857
LAGR: FJQ98_12675(vanR)
LMAC: I6G82_11600(vanR)
LCAP: ICJ70_17725(vanR)
LIU: OU989_06370(vanR)
LLB: R6U77_02730(vanR)
ALKL: MM271_03685(vanR)
BLR: BRLA_c026950(yycF_7)
BAYD: BSPP4475_08360(vanR)
PPM: PPSC2_11320(walR1)
PPO: PPM_2167(walR1)
PPOL: X809_11675
PPOY: RE92_01035
PRI: PRIO_4177(vanR7) PRIO_5443(vanR9)
PSWU: SY83_09600
PBK: Back11_54200(vanR)
PSOP: KP014_14555(vanR)
PUI: PUW25_20490(vanR)
PKP: SK3146_04798(walR_2)
TVU: AB849_010230(vanR)
SANS: DK43_03840
EFL: EF62_2957
EFI: OG1RF_12163(vanR)
EFS: EFS1_2268
EFQ: DR75_1554
ENE: ENT_19730
EMU: EMQU_0354
EIE: ENLAB_03640(ompR_1) ENLAB_26720(ompR_16)
MPS: MPTP_1883
MPX: MPD5_1678
CPR: CPR_0448
CTC: CTC_00805
CBO: CBO0365
CBA: CLB_0408
CBH: CLC_0423
CBY: CLM_0433
CBI: CLJ_B0421
CBT: CLH_2822
CKL: CKL_0022(vanR)
CKR: CKR_0014
CSR: Cspa_c11340(vanR2)
CPAS: Clopa_2273
CSB: CLSA_c16330(vanR2) CLSA_c24590(vanR3)
CLD: CLSPO_c02940(vanR6) CLSPO_c03960(vanR1) CLSPO_c22560(vanR5) CLSPO_c34750(vanR3)
CACE: CACET_c25500(vanR1)
CTYK: CTK_C03420(vanR)
CCOH: SAMEA4530647_0662(phoP_5)
CINT: HZF06_06790(vanR)
CCE: Ccel_2658
RPAY: P0092_11960(vanR)
ESR: ES1_00230
RUM: CK1_25690
OVA: OBV_09540
CAML: H6X83_02530(vanR)
PFAA: MM59RIKEN_12770(vanR)
VCOP: MM50RIKEN_08140(vanR)
LASA: L9O85_05985(vanR)
PALM: RBG61_03975(vanR)
CFEM: HCR03_17595(vanR) HCR03_19270(vanR)
AGAT: RWV98_19110(vanR)
DSY: DSY3689
DHD: Dhaf_1665
DED: DHBDCA_p1149(vanR)
DEC: DCF50_p1216(vanR)
DAE: Dtox_0488
ELM: ELI_1494
EMT: CPZ25_000840(vanR)
BPRM: CL3_17020
BPRS: CK3_33360
RIX: RO1_28780
CCT: CC1_22670
CCOM: I6K69_09035(vanR)
CEV: LK421_09125(vanR)
BLAU: DQQ01_06715(vanR)
BPRO: PMF13cell1_03978(phoP_3)
BLIQ: INP51_15870(vanR)
BWX: NQ550_13040(vanR)
BCOC: BLCOC_29280(phoP_1)
BHV: BLHYD_30320(walR_8)
CPY: Cphy_3518
CSCI: HDCHBGLK_01278(saeR) HDCHBGLK_01505(phoP_3)
ACAC: EYQ97_03395(vanR)
HSD: SD1D_0539(vanR)
DLO: K5I24_09375(vanR)
DFM: NQ560_14425(vanR)
SINT: K5I26_02880(vanR) K5I26_04905(vanR)
WCP: H9Q76_11105(vanR)
QDO: H9Q78_03840(vanR)
WHJ: H9Q79_00685(vanR) H9Q79_01740(vanR)
MFOR: NQ534_06785(vanR) NQ534_07970(vanR)
KIB: RBB56_07960(vanR)
CPRO: CPRO_11580(walR)
ABUT: Ami103574_02955(vanR) Ami103574_07945(vanR)
CDF: CD630_16240(vanR)
PHX: KGNDJEFE_00888(phoP_2)
HPRF: HLPR_02450
FMA: FMG_0123
APR: Apre_1833
TIS: P3962_14325(vanR)
TIZ: RBU61_00875(vanR)
AARG: Aargi30884_11280(vanR)
ABSI: A9CBEGH2_12400(vanR)
LCG: L3BBH23_19280(vanR_1) L3BBH23_22130(vanR_2)
EHN: H9Q80_05695(vanR)
CIU: G4D55_06595(vanR) G4D55_16940(vanR)
TFC: T23_01430
ERM: EYR00_11425(vanR)
TSF: NQ543_09460(vanR)
FBS: N510_001797(walR_1) N510_002078(phoP)
OLS: Olsu_1024
ELE: Elen_1631
AEQ: AEQU_0449
 » show all
Reference
  Authors
Hong HJ, Hutchings MI, Buttner MJ
  Title
Vancomycin resistance VanS/VanR two-component systems.
  Journal
Adv Exp Med Biol 631:200-13 (2008)
DOI:10.1007/978-0-387-78885-2_14

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