KEGG   ORTHOLOGY: K18385Help
Entry
K18385                      KO                                     

Name
PAXC, ATMC, LTMC
Definition
geranylgeranyldiphosphate transferase
Pathway
ko00403  Indole diterpene alkaloid biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00661  Paspaline biosynthesis, geranylgeranyl-PP + indoleglycerol phosphate => paspaline
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00403 Indole diterpene alkaloid biosynthesis
    K18385  PAXC, ATMC, LTMC; geranylgeranyldiphosphate transferase
BRITE hierarchy
Other DBs
RN: R10349
Genes
MAW: MAC_06939
MAJ: MAA_00080
BFU: BCIN_05g05670(Bcpax1)
AOR: AO090113000171
ANG: ANI_1_1738094(An11g02500) ANI_1_990034(An03g00850)
AFV: AFLA_096390
ACT: ACLA_008500
PCS: Pc20g01840
TaxonomyKoalaUniProt
Reference
  Authors
Nicholson MJ, Koulman A, Monahan BJ, Pritchard BL, Payne GA, Scott B
  Title
Identification of two aflatrem biosynthesis gene loci in Aspergillus flavus and metabolic engineering of Penicillium paxilli to elucidate their function.
  Journal
Appl Environ Microbiol 75:7469-81 (2009)
DOI:10.1128/AEM.02146-08
  Sequence
Reference
  Authors
Young C, McMillan L, Telfer E, Scott B
  Title
Molecular cloning and genetic analysis of an indole-diterpene gene cluster from Penicillium paxilli.
  Journal
Mol Microbiol 39:754-64 (2001)
DOI:10.1046/j.1365-2958.2001.02265.x
Reference
  Authors
Tagami K, Liu C, Minami A, Noike M, Isaka T, Fueki S, Shichijo Y, Toshima H, Gomi K, Dairi T, Oikawa H
  Title
Reconstitution of biosynthetic machinery for indole-diterpene paxilline in Aspergillus oryzae.
  Journal
J Am Chem Soc 135:1260-3 (2013)
DOI:10.1021/ja3116636

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