KEGG   ORTHOLOGY: K18387
Entry
K18387                      KO                                     

Name
PAXB, ATMB, LTMB
Definition
paspaline synthase
Pathway
ko00403  Indole diterpene alkaloid biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00661  Paspaline biosynthesis, geranylgeranyl-PP + indoleglycerol phosphate => paspaline
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00403 Indole diterpene alkaloid biosynthesis
    K18387  PAXB, ATMB, LTMB; paspaline synthase
Other DBs
RN: R10352 R10353
Genes
FGR: FGSG_12222
FPU: FPSE_10837
MAW: MAC_06940
MAJ: MAA_00081
BFU: BCIN_05g05660
AFM: AFUA_6G13950
NFI: NFIA_100490
AOR: AO090011000740
ANG: ANI_1_1736094(An11g02490)
AFV: AFLA_045510
Reference
  Authors
Nicholson MJ, Koulman A, Monahan BJ, Pritchard BL, Payne GA, Scott B
  Title
Identification of two aflatrem biosynthesis gene loci in Aspergillus flavus and metabolic engineering of Penicillium paxilli to elucidate their function.
  Journal
Appl Environ Microbiol 75:7469-81 (2009)
DOI:10.1128/AEM.02146-08
  Sequence
Reference
  Authors
Saikia S, Parker EJ, Koulman A, Scott B
  Title
Four gene products are required for the fungal synthesis of the indole-diterpene, paspaline.
  Journal
FEBS Lett 580:1625-30 (2006)
DOI:10.1016/j.febslet.2006.02.008
Reference
  Authors
Tagami K, Liu C, Minami A, Noike M, Isaka T, Fueki S, Shichijo Y, Toshima H, Gomi K, Dairi T, Oikawa H
  Title
Reconstitution of biosynthetic machinery for indole-diterpene paxilline in Aspergillus oryzae.
  Journal
J Am Chem Soc 135:1260-3 (2013)
DOI:10.1021/ja3116636

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