Entry |
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Symbol |
dfrA1, dhfr
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Name |
dihydrofolate reductase (trimethoprim resistance protein) [EC: 1.5.1.3]
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Pathway |
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Reaction |
R00936 | 5,6,7,8-tetrahydrofolate:NAD+ oxidoreductase |
R00937 | 5,6,7,8-tetrahydrofolate:NAD+ oxidoreductase |
R00939 | 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase |
R00940 | 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase |
R02235 | dihydrofolate:NAD+ oxidoreductase |
R02236 | dihydrofolate:NADP+ oxidoreductase |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
K18589 dfrA1, dhfr; dihydrofolate reductase (trimethoprim resistance protein)
00670 One carbon pool by folate
K18589 dfrA1, dhfr; dihydrofolate reductase (trimethoprim resistance protein)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
01504 Antimicrobial resistance genes
K18589 dfrA1, dhfr; dihydrofolate reductase (trimethoprim resistance protein)
Enzymes [BR:ko01000]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
K18589 dfrA1, dhfr; dihydrofolate reductase (trimethoprim resistance protein)
Antimicrobial resistance genes [BR:ko01504]
Gene variants
Trimethoprim resistance genes
Dihydrofolate reductases
K18589 dfrA1, dhfr; dihydrofolate reductase (trimethoprim resistance protein)
Antimicrobial resistance: KEGG signatures [br01600.html]
Signature KOs for antimicrobial resistance
K18589
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Other DBs |
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Genes |
» show all
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Reference |
|
Authors |
Agerso Y, Peirano G, Aarestrup FM |
Title |
dfrA25, a novel trimethoprim resistance gene from Salmonella Agona isolated from a human urine sample in Brazil. |
Journal |
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Reference |
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Authors |
Roberts MC, Schwarz S, Aarts HJ |
Title |
Erratum: Acquired antibiotic resistance genes: an overview. |
Journal |
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Reference |
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Authors |
Skold O |
Title |
Resistance to trimethoprim and sulfonamides. |
Journal |
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