ORTHOLOGY: K19643 Help
Entry
Symbol
dfrA10, dfr10
Name
dihydrofolate reductase (trimethoprim resistance protein) [EC:
1.5.1.3 ]
Pathway
Reaction
R00936 5,6,7,8-tetrahydrofolate:NAD+ oxidoreductase
R00937 5,6,7,8-tetrahydrofolate:NAD+ oxidoreductase
R00939 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase
R00940 5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase
R02235 dihydrofolate:NAD+ oxidoreductase
R02236 dihydrofolate:NADP+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
K19643 dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein)
00670 One carbon pool by folate
K19643 dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
01504 Antimicrobial resistance genes
K19643 dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein)
Enzymes [BR:ko01000 ]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
K19643 dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein)
Antimicrobial resistance genes [BR:ko01504 ]
Gene variants
Trimethoprim resistance genes
Dihydrofolate reductases
K19643 dfrA10, dfr10; dihydrofolate reductase (trimethoprim resistance protein)
Antimicrobial resistance: KEGG signatures [br01600.html ]
Signature KOs for antimicrobial resistance
K19643
BRITE hierarchy
Other DBs
Genes
Taxonomy UniProt
Reference
Authors
Parsons Y, Hall RM, Stokes HW
Title
A new trimethoprim resistance gene, dhfrX, in the In7 integron of plasmid pDGO100.
Journal
Sequence
Reference
Authors
Partridge SR, Hall RM
Title
In34, a complex In5 family class 1 integron containing orf513 and dfrA10.
Journal