KEGG   ORTHOLOGY: K18610Help
Entry
K18610                      KO                                     

Name
pdla
Definition
4-pyridoxolactonase [EC:3.1.1.27]
Pathway
ko00750  Vitamin B6 metabolism
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00750 Vitamin B6 metabolism
    K18610  pdla; 4-pyridoxolactonase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.27  4-pyridoxolactonase
     K18610  pdla; 4-pyridoxolactonase
BRITE hierarchy
Other DBs
RN: R02992
COG: COG0491
GO: 0047585
Genes
MLO: mlr6805
MLN: A9174_14090
MCI: Mesci_2030
MAM: Mesau_02094
MESW: A9K65_010590
MESM: EJ066_21290
MESP: C1M53_04555
MEY: TM49_03705
MMED: Mame_00111
TaxonomyKoalaUniProt
Reference
  Authors
Funami J, Yoshikane Y, Kobayashi H, Yokochi N, Yuan B, Iwasaki K, Ohnishi K, Yagi T
  Title
4-Pyridoxolactonase from a symbiotic nitrogen-fixing bacterium Mesorhizobium loti: cloning, expression, and characterization.
  Journal
Biochim Biophys Acta 1753:234-9 (2005)
DOI:10.1016/j.bbapap.2005.08.026
  Sequence
[mlo:mlr6805]

KEGG   ENZYME: 3.1.1.27Help
Entry
EC 3.1.1.27                 Enzyme                                 

Name
4-pyridoxolactonase
Class
Hydrolases;
Acting on ester bonds;
Carboxylic-ester hydrolases
BRITE hierarchy
Sysname
4-pyridoxolactone lactonohydrolase
Reaction(IUBMB)
4-pyridoxolactone + H2O = 4-pyridoxate [RN:R02992]
Reaction(KEGG)
Substrate
4-pyridoxolactone [CPD:C00971];
H2O [CPD:C00001]
Product
4-pyridoxate [CPD:C00847]
History
EC 3.1.1.27 created 1972
Pathway
ec00750  Vitamin B6 metabolism
ec01120  Microbial metabolism in diverse environments
Orthology
K18610  4-pyridoxolactonase
Genes
MLO: mlr6805
MLN: A9174_14090
MCI: Mesci_2030
MAM: Mesau_02094
MESW: A9K65_010590
MESM: EJ066_21290
MESP: C1M53_04555
MEY: TM49_03705
MMED: Mame_00111
Taxonomy
Reference
1  [PMID:4306030]
  Authors
Burg RW, Snell EE.
  Title
The bacterial oxidation of vitamin B6. VI. Pyridoxal dehydrogenase and 4-pyridoxolactonase.
  Journal
J Biol Chem 244:2585-9 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 3.1.1.27
IUBMB Enzyme Nomenclature: 3.1.1.27
ExPASy - ENZYME nomenclature database: 3.1.1.27
UM-BBD (Biocatalysis/Biodegradation Database): 3.1.1.27
BRENDA, the Enzyme Database: 3.1.1.27
CAS: 37278-41-4

KEGG   REACTION: R02992Help
Entry
R02992                      Reaction                               

Name
4-pyridoxolactone lactonohydrolase
Definition
4-Pyridoxolactone + H2O <=> 4-Pyridoxate
Equation
Reaction class
RC00826  C00847_C00971
Enzyme
Pathway
rn00750  Vitamin B6 metabolism
rn01120  Microbial metabolism in diverse environments
Orthology
K18610  4-pyridoxolactonase [EC:3.1.1.27]
Other DBs
RHEA: 14304

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