KEGG   ORTHOLOGY: K19066
Entry
K19066                      KO                                     

Name
E1.3.8.10
Definition
cyclohex-1-ene-1-carbonyl-CoA dehydrogenase [EC:1.3.8.10]
Pathway
ko00362  Benzoate degradation
ko01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00362 Benzoate degradation
    K19066  E1.3.8.10; cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.8  With a flavin as acceptor
    1.3.8.10  cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
     K19066  E1.3.8.10; cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Other DBs
RN: R09252
Genes
GME: Gmet_3306
GBM: Gbem_3575
GEO: Geob_2191
SAT: SYN_02587
Reference
  Authors
Kung JW, Seifert J, von Bergen M, Boll M
  Title
Cyclohexanecarboxyl-coenzyme A (CoA) and cyclohex-1-ene-1-carboxyl-CoA dehydrogenases, two enzymes involved in the fermentation of benzoate and crotonate in Syntrophus aciditrophicus.
  Journal
J Bacteriol 195:3193-200 (2013)
DOI:10.1128/JB.00322-13
  Sequence
[sat:SYN_02587]

KEGG   ENZYME: 1.3.8.10
Entry
EC 1.3.8.10                 Enzyme                                 

Name
cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Class
Oxidoreductases;
Acting on the CH-CH group of donors;
With a flavin as acceptor
Sysname
cyclohex-1-ene-1-carbonyl-CoA:electron transfer flavoprotein oxidoreductase
Reaction(IUBMB)
cyclohex-1-ene-1-carbonyl-CoA + electron-transfer flavoprotein = cyclohex-1,5-diene-1-carbonyl-CoA + reduced electron-transfer flavoprotein [RN:R09252]
Reaction(KEGG)
R09252
Substrate
cyclohex-1-ene-1-carbonyl-CoA [CPD:C09811];
electron-transfer flavoprotein [CPD:C04253]
Product
cyclohex-1,5-diene-1-carbonyl-CoA [CPD:C06322];
reduced electron-transfer flavoprotein [CPD:C04570]
Comment
Contains FAD. The enzyme, characterized from the strict anaerobic bacterium Syntrophus aciditrophicus, is involved in production of cyclohexane-1-carboxylate, a byproduct produced by that organism during fermentation of benzoate and crotonate to acetate.
History
EC 1.3.8.10 created 2013
Pathway
ec00362  Benzoate degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K19066  cyclohex-1-ene-1-carbonyl-CoA dehydrogenase
Genes
GME: Gmet_3306
GBM: Gbem_3575
GEO: Geob_2191
SAT: SYN_02587
Reference
1  [PMID:23667239]
  Authors
Kung JW, Seifert J, von Bergen M, Boll M
  Title
Cyclohexanecarboxyl-coenzyme A (CoA) and cyclohex-1-ene-1-carboxyl-CoA dehydrogenases, two enzymes involved in the fermentation of benzoate and crotonate in Syntrophus aciditrophicus.
  Journal
J Bacteriol 195:3193-200 (2013)
DOI:10.1128/JB.00322-13
  Sequence
[sat:SYN_02587]
Other DBs
ExplorEnz - The Enzyme Database: 1.3.8.10
IUBMB Enzyme Nomenclature: 1.3.8.10
ExPASy - ENZYME nomenclature database: 1.3.8.10
BRENDA, the Enzyme Database: 1.3.8.10

KEGG   REACTION: R09252
Entry
R09252                      Reaction                               

Name
cyclohex-1-ene-1-carbonyl-CoA:electron transfer flavoprotein oxidoreductase
Definition
Cyclohex-1-ene-1-carboxyl-CoA + Electron-transferring flavoprotein <=> Cyclohexa-1,5-diene-1-carbonyl-CoA + Reduced electron-transferring flavoprotein
Equation
Reaction class
RC00248  C06322_C09811
Enzyme
Pathway
rn00362  Benzoate degradation
rn01120  Microbial metabolism in diverse environments
rn01220  Degradation of aromatic compounds
Orthology
K19066  cyclohex-1-ene-1-carbonyl-CoA dehydrogenase [EC:1.3.8.10]
Other DBs
RHEA: 12996

DBGET integrated database retrieval system