KEGG   ORTHOLOGY: K19080
Entry
K19080                      KO                                     

Name
vraG
Definition
cationic antimicrobial peptide transport system permease protein
Pathway
ko01503  Cationic antimicrobial peptide (CAMP) resistance
ko02010  ABC transporters
ko02020  Two-component system
ko05150  Staphylococcus aureus infection
Module
M00730  Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
  09132 Signal transduction
   02020 Two-component system
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
  09175 Drug resistance: antimicrobial
   01503 Cationic antimicrobial peptide (CAMP) resistance
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
   01504 Antimicrobial resistance genes
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
Transporters [BR:ko02000]
 ABC transporters, prokaryotic type
  ABC-2 type and other transporters
   Cationic antimicrobial peptide transporter
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
Antimicrobial resistance genes [BR:ko01504]
 Gene sets
  CAMP resistance modules
   Cationic antimicrobial peptide (CAMP) resistance, VraFG transporter
    K19080  vraG; cationic antimicrobial peptide transport system permease protein
Other DBs
COG: COG0577
TC: 3.A.1.134.7
Genes
SDO: SD1155_06075
SAU: SA0617(vraG)
SAV: SAV0662(vraG)
SAW: SAHV_0659(vraG)
SAH: SaurJH1_0700
SAJ: SaurJH9_0685
SAM: MW0624(vraG)
SAS: SAS0627
SAR: SAR0672
SAC: SACOL0720
SAX: USA300HOU_0683(vraE)
SAA: SAUSA300_0648
SAO: SAOUHSC_00668
SAE: NWMN_0631(vraG)
SAD: SAAV_0624
SUU: M013TW_0649
SUV: SAVC_02940
SUE: SAOV_0696
SUJ: SAA6159_00616
SUK: SAA6008_00678
SUC: ECTR2_613
SUT: SAT0131_00732
SUQ: HMPREF0772_12526
SUZ: MS7_0712
SUD: ST398NM01_0740
SUX: SAEMRSA15_05880
SUW: SATW20_07370(vraG)
SUG: SAPIG0740
SUF: SARLGA251_05950(vraG)
SAUA: SAAG_01084
SAUE: RSAU_000638(bceB)
SAUN: SAKOR_00657
SAUS: SA40_0602(vraG)
SAUU: SA957_0617(vraG)
SAUG: SA268_0615(vraG)
SAUZ: SAZ172_0673(vraG)
SAUT: SAI1T1_2005120(vraG)
SAUJ: SAI2T2_1005140(vraG)
SAUK: SAI3T3_1005130(vraG)
SAUQ: SAI4T8_1005120(vraG)
SAUV: SAI7S6_1005130(vraG)
SAUW: SAI5S5_1005090(vraG)
SAUX: SAI6T6_1005100(vraG)
SAUY: SAI8T7_1005130(vraG)
SAUF: X998_0709
SAB: SAB0611
SUY: SA2981_0638(vraG)
SAUB: C248_0746
SAUM: BN843_6630
SAUC: CA347_676
SAUR: SABB_06076
SAUI: AZ30_03460
SAUD: CH52_02455
SAMS: NI36_03320
SUH: SAMSHR1132_06080
SER: SERP0315
SEP: SE0430
SEPP: SEB_00350
SEPS: DP17_1732
SHA: SH2232(vraG)
SHH: ShL2_02081
SCA: SCA_0305
SLG: SLGD_02163
SLN: SLUG_21360(vraG)
SWA: A284_10025
SPAS: STP1_1746
SCAP: AYP1020_0028(bceB_1)
SCV: A4G25_06150
SHOM: EGX58_02945
SCAR: DWB96_10925
SSH: NCTC13712_00626
SSIM: SAMEA4384339_0604(vraG)
 » show all
Reference
  Authors
Meehl M, Herbert S, Gotz F, Cheung A
  Title
Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus.
  Journal
Antimicrob Agents Chemother 51:2679-89 (2007)
DOI:10.1128/AAC.00209-07
  Sequence
[sac:SACOL0720]
Reference
  Authors
Yang SJ, Bayer AS, Mishra NN, Meehl M, Ledala N, Yeaman MR, Xiong YQ, Cheung AL
  Title
The Staphylococcus aureus two-component regulatory system, GraRS, senses and confers resistance to selected cationic antimicrobial peptides.
  Journal
Infect Immun 80:74-81 (2012)
DOI:10.1128/IAI.05669-11
  Sequence
[sav:SAV0662] [sac:SACOL0720]

  All links  
Ontology (5)   
   KEGG BRITE (3)   
   TC (1)   
   COG (1)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Gene (73)   
   KEGG GENES (72)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (89)   

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