KEGG ORTHOLOGY: K19106

ORTHOLOGY: K19106

Entry

K19106                      KO

Symbol

nocL

Name

nocardicin C N-oxygenase [EC:1.14.15.43]

Pathway

map00261

Monobactam biosynthesis

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00736

Nocardicin A biosynthesis, L-pHPG + arginine + serine => nocardicin A

Reaction

R10882

nocardicin C,reduced ferredoxin:O2 oxidoreductase (nocardicin A-forming)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    K19106  nocL; nocardicin C N-oxygenase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K19106  nocL; nocardicin C N-oxygenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.43  nocardicin C N-oxygenase
     K19106  nocL; nocardicin C N-oxygenase
Polyketide biosynthesis proteins [BR:ko01008]
Nonribosomal peptide tailoring proteins
  Oxygenase
   K19106  nocL; nocardicin C N-oxygenase

Other DBs

COG:

COG2124

Genes

NVU:	V7968_35150

SPRF:

AMI:

ACTI:

ACAD:

ACTA:

CROS:

AG:	AAT09797(nocL)

Reference

PMID:15629944

Authors

Kelly WL, Townsend CA

Title

Mutational analysis of nocK and nocL in the nocardicin a producer Nocardia uniformis.

Journal

J Bacteriol 187:739-46 (2005)
DOI:10.1128/JB.187.2.739-746.2005

Reference

PMID:15271351

Authors

Gunsior M, Breazeale SD, Lind AJ, Ravel J, Janc JW, Townsend CA

Title

The biosynthetic gene cluster for a monocyclic beta-lactam antibiotic, nocardicin A.

Journal

Chem Biol 11:927-38 (2004)
DOI:10.1016/j.chembiol.2004.04.012

Sequence

[ag:AAT09797]

All links

Ontology (1)   
   COG (1)   
Gene (1)   
   OC (1)   
All databases (2)   

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