KEGG   ORTHOLOGY: K19184Help
Entry
K19184                      KO                                     

Name
FGAAT
Definition
fumigaclavine B O-acetyltransferase [EC:2.3.1.205]
Pathway
ko00901  Indole alkaloid biosynthesis
ko01130  Biosynthesis of antibiotics
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00901 Indole alkaloid biosynthesis
    K19184  FGAAT; fumigaclavine B O-acetyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.205  fumigaclavine B O-acetyltransferase
     K19184  FGAAT; fumigaclavine B O-acetyltransferase
BRITE hierarchy
Other DBs
RN: R10200
Genes
ANI: AN9250.2
AFM: AFUA_2G18020
ANG: ANI_1_1240084(An09g02790) ANI_1_2062144(An16g08610)
ACT: ACLA_059750
TaxonomyKoalaUniProt
Reference
  Authors
Liu X, Wang L, Steffan N, Yin WB, Li SM
  Title
Ergot alkaloid biosynthesis in Aspergillus fumigatus: FgaAT catalyses the acetylation of fumigaclavine B.
  Journal
Chembiochem 10:2325-8 (2009)
DOI:10.1002/cbic.200900395
  Sequence

KEGG   ENZYME: 2.3.1.205Help
Entry
EC 2.3.1.205                Enzyme                                 

Name
fumigaclavine B O-acetyltransferase;
FgaAT
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy
Sysname
acetyl-CoA:fumigaclavine B O-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + fumigaclavine B = CoA + fumigaclavine A [RN:R10200]
Reaction(KEGG)
Substrate
acetyl-CoA [CPD:C00024];
fumigaclavine B [CPD:C20437]
Product
CoA [CPD:C00010];
fumigaclavine A [CPD:C20436]
Comment
The enzyme participates in the biosynthesis of fumigaclavine C, an ergot alkaloid produced by some fungi of the Trichocomaceae family.
History
EC 2.3.1.205 created 2012
Pathway
ec00901  Indole alkaloid biosynthesis
ec01130  Biosynthesis of antibiotics
Orthology
K19184  fumigaclavine B O-acetyltransferase
Genes
ANI: AN9250.2
AFM: AFUA_2G18020
ANG: ANI_1_1240084(An09g02790) ANI_1_2062144(An16g08610)
ACT: ACLA_059750
Taxonomy
Reference
1  [PMID:19672909]
  Authors
Liu X, Wang L, Steffan N, Yin WB, Li SM
  Title
Ergot alkaloid biosynthesis in Aspergillus fumigatus: FgaAT catalyses the acetylation of fumigaclavine B.
  Journal
Chembiochem 10:2325-8 (2009)
DOI:10.1002/cbic.200900395
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.205
IUBMB Enzyme Nomenclature: 2.3.1.205
ExPASy - ENZYME nomenclature database: 2.3.1.205
BRENDA, the Enzyme Database: 2.3.1.205

KEGG   REACTION: R10200Help
Entry
R10200                      Reaction                               

Name
acetyl-CoA:fumigaclavine B O-acetyltransferase
Definition
Acetyl-CoA + Fumigaclavine B <=> CoA + Fumigaclavine A
Equation
Reaction class
RC00004  C00010_C00024
RC00055  C20436_C20437
Enzyme
Pathway
rn00901  Indole alkaloid biosynthesis
rn01130  Biosynthesis of antibiotics
Orthology
K19184  fumigaclavine B O-acetyltransferase [EC:2.3.1.205]
Other DBs
RHEA: 34270

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