KEGG   ORTHOLOGY: K19270
Entry
K19270                      KO                                     

Name
hxpA
Definition
mannitol-1-/sugar-/sorbitol-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50]
Pathway
ko00051  Fructose and mannose metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K19270  hxpA; mannitol-1-/sugar-/sorbitol-6-phosphatase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.22  mannitol-1-phosphatase
     K19270  hxpA; mannitol-1-/sugar-/sorbitol-6-phosphatase
    3.1.3.23  sugar-phosphatase
     K19270  hxpA; mannitol-1-/sugar-/sorbitol-6-phosphatase
    3.1.3.50  sorbitol-6-phosphatase
     K19270  hxpA; mannitol-1-/sugar-/sorbitol-6-phosphatase
Other DBs
RN: R02167
COG: COG0637
GO: 0050084 0050308 0050286
Genes
ECO: b2293(hxpA)
ECJ: JW5376(yfbT)
ECD: ECDH10B_2455(yfbT)
EBW: BWG_2067(yfbT)
ECOK: ECMDS42_1864(yfbT)
ECE: Z3554(yfbT)
ECS: ECs3177
ECF: ECH74115_3432(yfbT)
ETW: ECSP_3167(yfbT)
ELX: CDCO157_2941
EOI: ECO111_3041(yfbT)
EOJ: ECO26_3281(yfbT)
EOH: ECO103_2757(yfbT)
ECOO: ECRM13514_3049(yfbT)
ECOH: ECRM13516_2993(yfbT)
ESL: O3K_08035
ESO: O3O_17600
ESM: O3M_07985
ECK: EC55989_2537(yfbT)
ECG: E2348C_2433(yfbT)
EOK: G2583_2830(yfbT)
ELH: ETEC_2428
ECW: EcE24377A_2586(yfbT)
EUN: UMNK88_2843(yfbT)
ECP: ECP_2332
ENA: ECNA114_2383(yfbT)
ECOS: EC958_2628(yfbT)
ECV: APECO1_4271(yfbT)
ECX: EcHS_A2442(yfbT)
ECM: EcSMS35_2448(yfbT)
ECY: ECSE_2550
ECR: ECIAI1_2367(yfbT)
EUM: ECUMN_2632(yfbT)
ECT: ECIAI39_2440(yfbT)
EOC: CE10_2675(yfbT)
EBR: ECB_02218(yfbT)
EBL: ECD_02218(yfbT)
EBE: B21_02178(yfbT)
EBD: ECBD_1366
ECI: UTI89_C2575(yfbT)
EIH: ECOK1_2526(yfbT)
ECZ: ECS88_2440(yfbT)
ECC: c2834(yfbT)
ESE: ECSF_2170
EKF: KO11_11235(yfbT)
EAB: ECABU_c26250(yfbT)
EDJ: ECDH1ME8569_2230(yfbT)
ELW: ECW_m2482(yfbT)
ELL: WFL_12145(yfbT)
ELC: i14_2633(yfbT)
ELD: i02_2633(yfbT)
ELP: P12B_c2387(yfbT)
ELF: LF82_3055(yfbT)
ECOI: ECOPMV1_02452(yfbT)
ECOJ: P423_12800
EFE: EFER_0876(yfbT)
EAL: EAKF1_ch3686(yfbT)
ESZ: FEM44_01645(hxpA)
STY: STY2564
STT: t0530
STM: STM2334(yfbT)
SEO: STM14_2877(yfbT)
SEY: SL1344_2303(yfbT)
SEJ: STMUK_2364(yfbT)
SEB: STM474_2431(yfbT)
SENI: CY43_12495
SPT: SPA0530(yfbT)
SEK: SSPA0494
SEI: SPC_1374(yfbT)
SEC: SCH_2335(yfbT)
SHB: SU5_02927
SENS: Q786_11515
SED: SeD_A2682
SEG: SG2363(yfbT)
SEL: SPUL_0554(yfbT)
SEGA: SPUCDC_0554(yfbT)
SET: SEN2316(yfbT)
SENA: AU38_11710
SENO: AU37_11720
SENV: AU39_11720
SENQ: AU40_13120
SENL: IY59_12040
SEEP: I137_02555
SENE: IA1_11630
SBG: SBG_2120
SBZ: A464_2449
SFL: SF2369(yfbT)
SFX: S2504(yfbT)
SFV: SFV_2360(yfbT)
SFE: SFxv_2614(yfbT)
SFN: SFy_3368
SFS: SFyv_3443
SFT: NCTC1_02604(yfbT_1)
SBO: SBO_2328(yfbT)
SBC: SbBS512_E2669(yfbT)
SDY: SDY_2489(yfbT)
ENC: ECL_03637
ECLX: LI66_15380
ECLY: LI62_16880
ECLZ: LI64_14815
EEC: EcWSU1_03166(yfbT)
ESA: ESA_00926
CSK: ES15_1181
CTU: CTU_29190(yfbT)
KPN: KPN_02683(yfbT)
KPU: KP1_3930(yfbT)
KPP: A79E_1418
KPR: KPR_2022(yfbT)
KPJ: N559_1569
KPX: PMK1_00181(yfbT)
KPNU: LI86_07655
KPNK: BN49_3901(yfbT)
KVA: Kvar_1370
KPE: KPK_1464(yfbT)
KOX: KOX_26420
KOE: A225_4185
EAE: EAE_24455
EAR: CCG28929
CRO: ROD_26951
CKO: CKO_00502
EBT: EBL_c12610(yfbT)
RTG: NCTC13098_01976(yfbT_1) NCTC13098_03168(yfbT_2)
REE: electrica_01464(yfbT)
CLAP: NCTC11466_01300(yfbT_1)
KIE: NCTC12125_00383(yfbT_1)
AHN: NCTC12129_01520(yfbT_1)
EBF: D782_1378
PSTS: E05_23250(yfbT)
YPE: YPO2562
YPK: y1625
YPH: YPC_1551(yfbT)
YPA: YPA_2052
YPN: YPN_2155
YPM: YP_2373
YPZ: YPZ3_2264
YPD: YPD4_2451
YPX: YPD8_2146
YPW: CH59_95
YPJ: CH55_50
YPV: BZ15_976
YPL: CH46_2554
YPS: YPTB2593
YPO: BZ17_4045
YPY: YPK_1554
YPB: YPTS_2688
YPQ: DJ40_3950
YPU: BZ21_1889
YPR: BZ20_3616
YPC: BZ23_2173
YPF: BZ19_1954
YEN: YE1337
YEY: Y11_02081
YEW: CH47_756
YET: CH48_317
YAL: AT01_1189
YFR: AW19_1868
YIN: CH53_388
YKR: CH54_3917
YRO: CH64_1209
SMAR: SM39_2907
SMW: SMWW4_v1c34220(yfbT)
SPE: Spro_3313
SRL: SOD_c32290(yfbT)
SPLY: Q5A_017530(yfbT)
SMAF: D781_3103
SERF: L085_11570
SFJ: SAMEA4384070_3429(yfbT)
SOF: NCTC11214_03364(yfbT)
RAA: Q7S_06030
ECA: ECA3036
PATR: EV46_15000
PATO: GZ59_30410
PCT: PC1_2777
PEC: W5S_1372
SOD: Sant_0840(yfbT) Sant_1337
DDD: Dda3937_04024(yfbT)
DDQ: DDI_2716
DAQ: DAQ1742_01347(yfbT)
EAM: EAMY_2382(yfbT)
EAY: EAM_2299
ETA: ETA_11960
EPY: EpC_12520
EPR: EPYR_01333(yfbT)
EBI: EbC_30840
EGE: EM595_2513(yfbT)
PAM: PANA_2640(yfbT)
PLF: PANA5342_1416(yfbT)
PAJ: PAJ_1928(yfbT)
PVA: Pvag_2110(yfbT)
PSTW: DSJ_17095
MINT: C7M51_02108(yfbT)
MTHI: C7M52_00739(yfbT)
PMR: PMI1768
PHAU: PH4a_00555
XBO: XBJ1_1113(yfbT) XBJ1_2932(yfbT)
XBV: XBW1_3152(yfbT)
XNE: XNC1_2804(yfbT)
XNM: XNC2_2699(yfbT)
XDO: XDD1_2601(yfbT)
PSI: S70_02430
PSX: DR96_3648
PRG: RB151_026780(yfbT)
PHEI: NCTC12003_01549(yfbT)
PRJ: NCTC6933_02349(yfbT)
MMK: MU9_2563
ANS: ArsFIN_26490(yfbT)
LRI: NCTC12151_02310(yfbT)
PSHI: SAMEA2665130_0780(yfbT)
ADP: NCTC12871_00896(yfbT)
PFS: PFLU_4168
PFE: PSF113_2294(yfbT)
PFB: VO64_1247
PMAN: OU5_6025
PANR: A7J50_3848
PSIL: PMA3_10700
PSEN: PNC201_19830(yfbT)
MVS: MVIS_1438
AHA: AHA_3234
ASA: ASA_1080
AVR: B565_0923
AMED: B224_0963
AEL: NCTC12917_01082(yfbT)
TAU: Tola_2350
SALN: SALB1_2054
PLG: NCTC10937_01570(yfbT_1)
CABA: SBC2_38690(hxpA_1)
JAG: GJA_1762
CARE: LT85_3092
MLO: mlr4094
MHUA: MCHK_5359
AMIH: CO731_02953(yfbT)
SME: SM_b21214(orf24)
SMER: DU99_29010
SMD: Smed_4703
SFD: USDA257_c11290(yfbT)
ATU: Atu3251
RIR: BN877_II1596(yfbT)
RHT: NT26_2001(yfbT)
SHZ: shn_20780
BME: BMEI1105
BMEL: DK63_308
BMEE: DK62_551
BMF: BAB1_0880
BABO: DK55_872
BABR: DO74_1017
BABT: DK49_630
BABB: DK48_1246
BABU: DK53_856
BABS: DK51_602
BABC: DO78_777
BMS: BR0861
BSZ: DK67_1764
BOV: BOV_0852
BCAR: DK60_919
BCAS: DA85_04095
BMR: BMI_I858
BPP: BPI_I897
BPV: DK65_510
OAN: Oant_2365
OAH: DR92_1825
MOR: MOC_3890
THD: BHV28_05650(yfbT)
CAK: Caul_2162
CSE: Cseg_1615
PDE: Pden_4839
SSAN: NX02_03675
SINB: SIDU_17695
SSI: SSU0684
SUP: YYK_03265
MYO: OEM_44950
MUL: MUL_0545
MMI: MMAR_0580
MSHG: MSG_03286
RER: RER_54450
REY: O5Y_25930
RHB: NY08_87
RHS: A3Q41_04755(yfbT)
TPR: Tpau_3077
SCO: SCO1560(SCL11.16c) SCO2346(SCC8A.04c)
SGR: SGR_5163
SGB: WQO_09555
SCT: SCAT_1450(yfbT) SCAT_5264
SFA: Sfla_4489
SHY: SHJG_3840
SALS: SLNWT_5481
STRP: F750_2202(yfbT)
SFI: SFUL_1923
SALU: DC74_2830
SALL: SAZ_15525
STRM: M444_11845
SRW: TUE45_01979(yfbT_1) TUE45_02936(yfbT_2)
SLE: sle_45840(sle_45840) sle_48500(sle_48500)
SRN: A4G23_01474(yfbT)
SLAU: SLA_1964
SALJ: SMD11_4747
SLX: SLAV_25520(yfbT1) SLAV_35380(yfbT3)
SGE: DWG14_05945(yfbT_1) DWG14_06925(yfbT_2)
LXX: Lxx02170
CMI: CMM_0223
CMS: CMS0789
CMC: CMN_00161
MLV: CVS47_02958(yfbT)
MOY: CVS54_01166(yfbT_1) CVS54_03158(yfbT_2)
ART: Arth_0649
AAU: AAur_0798
JDE: Jden_2195
CFL: Cfla_0403
CFI: Celf_0447
SERJ: SGUI_3174
DCO: SAMEA4475696_0301(yfbT)
PAC: PPA0030
PACC: PAC1_00145
PACH: PAGK_0027
CACN: RN83_00570
CGRN: 4412665_00576(yfbT_1) 4412665_01198(yfbT_2)
PAUS: NCTC13651_02422(yfbT)
ACIJ: JS278_02765(yfbT)
KFL: Kfla_4821
TFU: Tfu_2488
NDA: Ndas_3540
NAL: B005_2979
STRR: EKD16_04770(yfbT1) EKD16_12645(yfbT2)
SRO: Sros_1428
KRA: Krad_1478
SEN: SACE_1848(yfbT)
PDX: Psed_2940
PSEA: WY02_23795
PSEE: FRP1_05045
PSEH: XF36_06930
PAUT: Pdca_18370
AMI: Amir_3098
SESP: BN6_52590
AHG: AHOG_27475(yfbT)
SAQ: Sare_4784
ACTN: L083_6138
AFS: AFR_31435
CWO: Cwoe_3319
CTHE: Chro_3582
ACA: ACP_3310(yfbT)
ABAS: ACPOL_1367
TAI: Taci_0546
GBA: J421_0733
SRU: SRU_2748
SRM: SRM_02959(yfbT)
 » show all
Reference
  Authors
Kuznetsova E, Proudfoot M, Gonzalez CF, Brown G, Omelchenko MV, Borozan I, Carmel L, Wolf YI, Mori H, Savchenko AV, Arrowsmith CH, Koonin EV, Edwards AM, Yakunin AF
  Title
Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family.
  Journal
J Biol Chem 281:36149-61 (2006)
DOI:10.1074/jbc.M605449200
  Sequence
[eco:b2293]
Reference
  Authors
Sevin DC, Fuhrer T, Zamboni N, Sauer U
  Title
Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli.
  Journal
Nat Methods 14:187-194 (2017)
DOI:10.1038/nmeth.4103
  Sequence
[eco:b2293]

KEGG   ORTHOLOGY: K24204
Entry
K24204                      KO                                     

Name
hxpB
Definition
mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50 3.1.3.68]
Pathway
ko00051  Fructose and mannose metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00051 Fructose and mannose metabolism
    K24204  hxpB; mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.22  mannitol-1-phosphatase
     K24204  hxpB; mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase
    3.1.3.23  sugar-phosphatase
     K24204  hxpB; mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase
    3.1.3.50  sorbitol-6-phosphatase
     K24204  hxpB; mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase
    3.1.3.68  2-deoxyglucose-6-phosphatase
     K24204  hxpB; mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase
Other DBs
RN: R02167
COG: COG0637
GO: 0050084 0050308 0050286 0003850
Genes
LCQ: 111685533 111688238
ECO: b1727(hxpB)
ECJ: JW1716(yniC)
ECD: ECDH10B_1865(yniC)
EBW: BWG_1540(yniC)
ECOK: ECMDS42_1402(yniC)
ECE: Z2756
ECS: ECs2433
ECF: ECH74115_2445
ETW: ECSP_2295(yniC)
EOI: ECO111_2237(yniC)
EOJ: ECO26_2500(yniC)
EOH: ECO103_1919(yniC)
ECOO: ECRM13514_2224(yniC)
ECOH: ECRM13516_2129(yniC)
ESL: O3K_11345
ESO: O3O_14285
ESM: O3M_11315
ECK: EC55989_1894(yniC)
ELH: ETEC_1759
ECP: ECP_1674
ENA: ECNA114_1773(yniC)
ECOS: EC958_1949(yniC)
ECV: APECO1_797(yniC)
ECY: ECSE_1896
ECR: ECIAI1_1785(yniC)
ECQ: ECED1_1930(yniC)
EUM: ECUMN_2016(yniC)
ECT: ECIAI39_1327(yniC)
EOC: CE10_2006(yniC)
EBR: ECB_01696(yniC)
EBL: ECD_01696(yniC)
EBE: B21_01684(yniC)
EBD: ECBD_1918
ECI: UTI89_C1921(yniC)
ECZ: ECS88_1779(yniC)
ECC: c2126(yniC)
ESE: ECSF_1589
EKF: KO11_14105(yniC)
EAB: ECABU_c19830(yniC)
EDJ: ECDH1ME8569_1671(yniC)
ELW: ECW_m1896(yniC)
ELL: WFL_09290(yniC)
ELC: i14_1947(yniC)
ELD: i02_1947(yniC)
ELP: P12B_c1356(yniC)
ELF: LF82_3582(yniC)
ECOI: ECOPMV1_01826(yniC)
ECOJ: P423_09200
EFE: EFER_1340(yniC) EFER_2173
ESZ: FEM44_23570(hxpB)
STY: STY1789
STT: t1202
STM: STM1322(yniC)
SEO: STM14_1606(yniC)
SEY: SL1344_1257(yniC)
SEJ: STMUK_1289(yniC)
SEB: STM474_1327(yniC)
SENI: CY43_06735
SPT: SPA1522(yniC)
SEK: SSPA1413
SEI: SPC_2408(yniC)
SEC: SCH_1343(yniC)
SHB: SU5_01941
SENS: Q786_08645
SED: SeD_A2022
SEG: SG1794(yniC)
SEL: SPUL_1139(yniC)
SEGA: SPUCDC_1139(yniC)
SET: SEN1721(yniC)
SENA: AU38_08910
SENO: AU37_08915
SENV: AU39_08920
SENQ: AU40_09950
SENL: IY59_09115
SEEP: I137_05235
SENB: BN855_13590(yniC)
SENE: IA1_06525
SBG: SBG_1176
SBZ: A464_1277
SALZ: EOS98_12855(hxpB)
SFL: SF1503(yniC)
SFX: S1620(yniC)
SFV: SFV_1494(yniC)
SFE: SFxv_1686(yniC)
SFN: SFy_2156
SFS: SFyv_2208
SFT: NCTC1_01621(yniC)
SSN: SSON_1430(yniC)
SBO: SBO_1363(yniC)
SDY: SDY_1820(yniC)
ENC: ECL_02428
ECLX: LI66_09105
ECLZ: LI64_09170
EEC: EcWSU1_01802(yniC)
ECHG: FY206_10510(hxpB)
EBG: FAI37_20225(hxpB)
ESA: ESA_02138
CSK: ES15_2289
CTU: CTU_18320(yniC)
KPN: KPN_01241(yniC) KPN_02540
KPU: KP1_2275(yniC) KP1_3757
KPR: KPR_1559 KPR_2290(yniC)
KPX: PMK1_00027(yniC_1) PMK1_03620(yniC_2)
KPNK: BN49_2377(yniC) BN49_3757
EAE: EAE_21505
EAR: CCG29636
CRO: ROD_13291
CPOT: FOB25_01300(hxpB)
CAMA: F384_06010
SECT: A359_02080
EBT: EBL_c15800(yniC)
RTG: NCTC13098_02233(yniC_1) NCTC13098_04188(yniC_2)
REE: electrica_01617(yniC_1) electrica_02991(yniC_2)
CLAP: NCTC11466_02657(yniC)
KOT: EH164_12870(hxpB)
KIE: NCTC12125_01643(yniC)
LER: GNG29_09510(hxpB)
LEA: GNG26_09170(hxpB)
LNI: CWR52_03075(hxpB)
BUF: D8682_25080(hxpB)
AHN: NCTC12129_02286(yniC)
IZH: FEM41_16060(hxpB)
YRE: HEC60_04255(hxpB)
SGOE: A8O29_013475(hxpB)
PDZ: HHA33_12820(hxpB)
EBF: D782_2534
PSTS: E05_12230
YPE: YPO2446
YPK: y1890
YPH: YPC_2087
YPA: YPA_1790
YPN: YPN_1900
YPM: YP_2233
YPZ: YPZ3_1447
YPD: YPD4_1412
YPX: YPD8_1534
YPW: CH59_4278(yniC)
YPJ: CH55_520(yniC)
YPV: BZ15_1081(yniC)
YPL: CH46_2661(yniC)
YPS: YPTB2354
YPO: BZ17_102(yniC)
YPY: YPK_1808
YPB: YPTS_2428
YPQ: DJ40_4219(yniC)
YPU: BZ21_1640(yniC)
YPR: BZ20_3853(yniC)
YPC: BZ23_1926(yniC)
YPF: BZ19_1717(yniC)
YEN: YE1890
YEY: Y11_07621
YEW: CH47_1324(yniC)
YET: CH48_3597(yniC)
YAL: AT01_230(yniC)
YFR: AW19_1427(yniC)
YIN: CH53_4258(yniC)
YKR: CH54_235
YRO: CH64_771(yniC)
YRU: BD65_512(yniC)
YHI: D5F51_07695(hxpB)
YCA: F0T03_09910(hxpB)
YMO: HRD69_14710(hxpB)
SMAR: SM39_1585
SMW: SMWW4_v1c21510(yniC)
SPE: Spro_2125
SRL: SOD_c19390(yniC)
SPLY: Q5A_010735(yniC)
SMAF: D781_1953
SERF: L085_18000
SQU: E4343_05595(hxpB)
SFJ: SAMEA4384070_2183(yniC)
SOF: NCTC11214_04716(yniC)
RAA: Q7S_14325
EAME: GXP68_08215(hxpB)
ECA: ECA2398
PATR: EV46_11550
PATO: GZ59_21590
PCT: PC1_1912
PEC: W5S_2147
PPUJ: E2566_10225(hxpB)
SOD: Sant_2088(yniC)
SENY: HBA_0573(yniC)
BRB: EH207_09420(hxpB)
BNG: EH206_11705(hxpB)
ETA: ETA_18460(yniC)
EPY: EpC_19350(yniC)
EPR: EPYR_02091(yniC)
EBI: EbC_18740(yniC)
ERJ: EJP617_27830(yniC)
EGE: EM595_1654(yniC)
ERWI: GN242_08985(hxpB)
PAM: PANA_1689(yniC)
PLF: PANA5342_2525(yniC)
PAJ: PAJ_1038(yniC)
PVA: Pvag_1130(yniC)
PANS: FCN45_08530(hxpB)
PEY: EE896_10715(hxpB)
PDIS: D8B20_07555(hxpB)
MINT: C7M51_01128(yniC)
MTHI: C7M52_01627(yniC)
TPTY: NCTC11468_01723(yniC)
PLU: plu2678
PMR: PMI1021
PHAU: PH4a_14130
PCIB: F9282_08225(hxpB)
PCOL: F1325_08275(hxpB)
XBV: XBW1_2344(yniC)
XNE: XNC1_1815(yniC)
XNM: XNC2_1761(yniC)
XDO: XDD1_3622
XPO: XPG1_1349 XPG1_1528(yniC)
PSI: S70_19225
PSX: DR96_2757(yniC)
PRG: RB151_018990(yniC)
PHEI: NCTC12003_02357(yniC)
PRQ: CYG50_07920(hxpB)
PRJ: NCTC6933_01614(yniC)
PVC: G3341_12085(hxpB)
MMK: MU9_2457
ASY: AUT07_00247(yniC)
ANS: ArsFIN_16340(yniC)
ETR: ETAE_1570
ETD: ETAF_1460(yniC)
ETE: ETEE_3580
PRAG: EKN56_09175(hxpB)
PSHI: SAMEA2665130_1528(yniC)
HAP: HAPS_0179(yniC)
HPAZ: K756_06170
HPAS: JL26_05130
HPAK: JT17_02695
HSO: HS_0674
HSM: HSM_1083
MSU: MS1050
MHT: D648_1220
MHAT: B824_400
MHX: MHH_c06580(yniC)
MHAE: F382_07535
MHAM: J450_07505
MHAO: J451_08435
MHAL: N220_00540
MHAQ: WC39_13525
MHAY: VK67_13530
MVR: X781_600
APL: APL_1213
APJ: APJL_1226
APA: APP7_1264
ASU: Asuc_0616
AIO: EXH44_10860(hxpB)
ALIG: NCTC10568_01515(yniC)
BTO: WQG_7770
BTRE: F542_14280
BTRH: F543_15930
BTRA: F544_8120
AVT: NCTC3438_01273(yniC)
PAET: NCTC13378_00613(yniC)
VAG: N646_4036
VNL: D3H41_19590(hxpB)
PPR: PBPRA2175(Z2756)
SALY: E8E00_06995(hxpB)
SKS: FCN78_06415(hxpB)
SCOT: HBA18_06675(hxpB)
SON: SO_0431(yniC)
SDN: Sden_3378
SFR: Sfri_3772
SAZ: Sama_0381
SBL: Sbal_3906
SLO: Shew_3425
SSE: Ssed_0437
SPL: Spea_0424
SHL: Shal_0481
SWD: Swoo_0284
SWP: swp_4741
SVO: SVI_0270
SPSW: Sps_05372
SLJ: EGC82_02990(hxpB)
SMAI: EXU30_11535(hxpB)
SPOL: FH971_18920(hxpB)
SKH: STH12_04079(yniC)
SALH: HMF8227_02762(yfbT)
FBL: Fbal_0374
FES: HER31_17635(hxpB)
MEJ: Q7A_1748
MEC: Q7C_974
NIK: F5I99_03715(hxpB)
AHA: AHA_2118
ASA: ASA_2182
AVR: B565_1809
AMED: B224_2109
ASR: WL1483_3712(yniC)
ACAV: VI35_10245
AEL: NCTC12917_01986(yniC)
TAU: Tola_1391
ORB: IPMB12_04040(hxpB)
FMR: Fuma_01744(yniC)
MBAS: ALGA_1281
CPI: Cpin_6618
CHIT: FW415_08785(hxpB)
CHIH: GWR21_12565(hxpB)
ARK: D6B99_04990(hxpB)
AGI: FSB73_02640(hxpB)
ARAC: E0W69_012180(hxpB)
PSEG: D3H65_14535(hxpB)
PGIN: FRZ67_21080(hxpB)
PGO: FSB84_29445(hxpB)
FLS: GLV81_04385(hxpB)
LACS: H4075_08210(hxpB)
SPDR: G6053_17620(hxpB)
SDJ: NCTC13534_03153(yqaB_1)
DFE: Dfer_4825
SLI: Slin_2846
SPIK: EXU85_19425(hxpB)
SPIB: G8759_31610(hxpB)
LBY: Lbys_0379
FJO: Fjoh_2690
MPW: MPR_0422
CHZ: CHSO_2113
CNK: EG343_24550(hxpB)
CLAC: EG342_15610(hxpB)
 » show all
Reference
  Authors
Kuznetsova E, Proudfoot M, Gonzalez CF, Brown G, Omelchenko MV, Borozan I, Carmel L, Wolf YI, Mori H, Savchenko AV, Arrowsmith CH, Koonin EV, Edwards AM, Yakunin AF
  Title
Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family.
  Journal
J Biol Chem 281:36149-61 (2006)
DOI:10.1074/jbc.M605449200
  Sequence
[eco:b1727]
Reference
  Authors
Sevin DC, Fuhrer T, Zamboni N, Sauer U
  Title
Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli.
  Journal
Nat Methods 14:187-194 (2017)
DOI:10.1038/nmeth.4103
  Sequence
[eco:b1727]

KEGG   ENZYME: 3.1.3.22
Entry
EC 3.1.3.22                 Enzyme                                 

Name
mannitol-1-phosphatase;
mannitol-1-phosphate phosphatase
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
D-mannitol-1-phosphate phosphohydrolase
Reaction(IUBMB)
D-mannitol 1-phosphate + H2O = D-mannitol + phosphate [RN:R02167]
Reaction(KEGG)
R02167
Substrate
D-mannitol 1-phosphate [CPD:C00644];
H2O [CPD:C00001]
Product
D-mannitol [CPD:C00392];
phosphate [CPD:C00009]
History
EC 3.1.3.22 created 1972
Pathway
ec00051  Fructose and mannose metabolism
ec01100  Metabolic pathways
Orthology
K19270  mannitol-1-/sugar-/sorbitol-6-phosphatase
K24204  mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase
Genes
LCQ: 111685533 111688238
ECO: b1727(hxpB) b2293(hxpA)
ECJ: JW1716(yniC) JW5376(yfbT)
ECD: ECDH10B_1865(yniC) ECDH10B_2455(yfbT)
EBW: BWG_1540(yniC) BWG_2067(yfbT)
ECOK: ECMDS42_1402(yniC) ECMDS42_1864(yfbT)
ECE: Z2756 Z3554(yfbT)
ECS: ECs2433 ECs3177
ECF: ECH74115_2445 ECH74115_3432(yfbT)
ETW: ECSP_2295(yniC) ECSP_3167(yfbT)
EOI: ECO111_2237(yniC) ECO111_3041(yfbT)
EOJ: ECO26_2500(yniC) ECO26_3281(yfbT)
EOH: ECO103_1919(yniC) ECO103_2757(yfbT)
ECOO: ECRM13514_2224(yniC) ECRM13514_3049(yfbT)
ECOH: ECRM13516_2129(yniC) ECRM13516_2993(yfbT)
ECK: EC55989_1894(yniC) EC55989_2537(yfbT)
EOK: G2583_2173(yniC) G2583_2614 G2583_2830(yfbT)
ENA: ECNA114_1773(yniC) ECNA114_2383(yfbT)
ECOS: EC958_1949(yniC) EC958_2628(yfbT)
ECV: APECO1_4271(yfbT) APECO1_797(yniC)
ECR: ECIAI1_1785(yniC) ECIAI1_2367(yfbT)
ECQ: ECED1_1013 ECED1_1930(yniC) ECED1_2757(yfbT)
EUM: ECUMN_2016(yniC) ECUMN_2632(yfbT)
ECT: ECIAI39_1327(yniC) ECIAI39_2440(yfbT)
EOC: CE10_2006(yniC) CE10_2675(yfbT)
EBR: ECB_01696(yniC) ECB_02218(yfbT)
EBL: ECD_01696(yniC) ECD_02218(yfbT)
EBE: B21_01684(yniC) B21_02178(yfbT)
ECI: UTI89_C1921(yniC) UTI89_C2575(yfbT)
ECZ: ECS88_1779(yniC) ECS88_2440(yfbT)
ECC: c2126(yniC) c2834(yfbT)
EKF: KO11_11235(yfbT) KO11_14105(yniC)
EAB: ECABU_c19830(yniC) ECABU_c26250(yfbT)
ELW: ECW_m1896(yniC) ECW_m2482(yfbT)
ELL: WFL_09290(yniC) WFL_12145(yfbT)
ELC: i14_1947(yniC) i14_2633(yfbT)
ELD: i02_1947(yniC) i02_2633(yfbT)
ELP: P12B_c1356(yniC) P12B_c2387(yfbT)
ELF: LF82_3055(yfbT) LF82_3582(yniC)
ECOI: ECOPMV1_01826(yniC) ECOPMV1_02452(yfbT)
EFE: EFER_0876(yfbT) EFER_1340(yniC) EFER_2173
ESZ: FEM44_01645(hxpA) FEM44_23570(hxpB)
STT: t0530 t1202
STM: STM1322(yniC) STM2334(yfbT)
SEO: STM14_1606(yniC) STM14_2877(yfbT)
SEY: SL1344_1257(yniC) SL1344_2303(yfbT)
SEJ: STMUK_1289(yniC) STMUK_2364(yfbT)
SEB: STM474_1327(yniC) STM474_2431(yfbT)
SPT: SPA0530(yfbT) SPA1522(yniC)
SEI: SPC_1374(yfbT) SPC_2408(yniC)
SEC: SCH_1343(yniC) SCH_2335(yfbT)
SEG: SG1794(yniC) SG2363(yfbT)
SEL: SPUL_0554(yfbT) SPUL_1139(yniC)
SEGA: SPUCDC_0554(yfbT) SPUCDC_1139(yniC)
SET: SEN1721(yniC) SEN2316(yfbT)
SFL: SF1503(yniC) SF2369(yfbT)
SFX: S1620(yniC) S2504(yfbT)
SFV: SFV_1494(yniC) SFV_2360(yfbT)
SFE: SFxv_1686(yniC) SFxv_2614(yfbT)
SFT: NCTC1_01621(yniC) NCTC1_02604(yfbT_1)
SSN: SSON_1430(yniC)
SBO: SBO_1363(yniC) SBO_2328(yfbT)
SDY: SDY_1820(yniC) SDY_2489(yfbT)
EEC: EcWSU1_01802(yniC) EcWSU1_03166(yfbT)
CTU: CTU_18320(yniC) CTU_29190(yfbT)
KPN: KPN_01241(yniC) KPN_02540 KPN_02683(yfbT)
KPU: KP1_2275(yniC) KP1_3757 KP1_3930(yfbT)
KPR: KPR_1559 KPR_2022(yfbT) KPR_2290(yniC)
KPX: PMK1_00027(yniC_1) PMK1_00181(yfbT) PMK1_03620(yniC_2)
KPNK: BN49_2377(yniC) BN49_3757 BN49_3901(yfbT)
SECT: A359_02080
EBT: EBL_c12610(yfbT) EBL_c15800(yniC)
RTG: NCTC13098_01976(yfbT_1) NCTC13098_02233(yniC_1) NCTC13098_03168(yfbT_2) NCTC13098_04188(yniC_2)
REE: electrica_01464(yfbT) electrica_01617(yniC_1) electrica_02991(yniC_2)
CLAP: NCTC11466_01300(yfbT_1) NCTC11466_02657(yniC)
KIE: NCTC12125_00383(yfbT_1) NCTC12125_01643(yniC)
AHN: NCTC12129_01520(yfbT_1) NCTC12129_02286(yniC)
PSTS: E05_12230 E05_23250(yfbT)
YPK: y1625 y1890
YPH: YPC_1551(yfbT) YPC_2087
YPW: CH59_4278(yniC) CH59_95
YPJ: CH55_50 CH55_520(yniC)
YPV: BZ15_1081(yniC) BZ15_976
YPL: CH46_2554 CH46_2661(yniC)
YPO: BZ17_102(yniC) BZ17_4045
YPQ: DJ40_3950 DJ40_4219(yniC)
YPU: BZ21_1640(yniC) BZ21_1889
YPR: BZ20_3616 BZ20_3853(yniC)
YPC: BZ23_1926(yniC) BZ23_2173
YPF: BZ19_1717(yniC) BZ19_1954
YEW: CH47_1324(yniC) CH47_756
YET: CH48_317 CH48_3597(yniC)
YAL: AT01_1189 AT01_230(yniC)
YFR: AW19_1427(yniC) AW19_1868
YIN: CH53_388 CH53_4258(yniC)
YRO: CH64_1209 CH64_771(yniC)
YRU: BD65_512(yniC)
SMW: SMWW4_v1c21510(yniC) SMWW4_v1c34220(yfbT)
SRL: SOD_c19390(yniC) SOD_c32290(yfbT)
SPLY: Q5A_010735(yniC) Q5A_017530(yfbT)
SOD: Sant_0840(yfbT) Sant_1337 Sant_2088(yniC)
SENY: HBA_0573(yniC)
DDD: Dda3937_04024(yfbT)
DDQ: DDI_2716
DAQ: DAQ1742_01347(yfbT)
EAM: EAMY_2382(yfbT)
EAY: EAM_2299
ETA: ETA_11960 ETA_18460(yniC)
EPY: EpC_12520 EpC_19350(yniC)
EPR: EPYR_01333(yfbT) EPYR_02091(yniC)
EBI: EbC_18740(yniC) EbC_30840
EGE: EM595_1654(yniC) EM595_2513(yfbT)
PAM: PANA_1689(yniC) PANA_2640(yfbT)
PLF: PANA5342_1416(yfbT) PANA5342_2525(yniC)
PAJ: PAJ_1038(yniC) PAJ_1928(yfbT)
PVA: Pvag_1130(yniC) Pvag_2110(yfbT)
PSTW: DSJ_17095
MINT: C7M51_01128(yniC) C7M51_02108(yfbT)
MTHI: C7M52_00739(yfbT) C7M52_01627(yniC)
TPTY: NCTC11468_01723(yniC)
PLU: plu2678
XBO: XBJ1_1113(yfbT) XBJ1_2932(yfbT)
XBV: XBW1_2344(yniC) XBW1_3152(yfbT)
XNE: XNC1_1815(yniC) XNC1_2804(yfbT)
XNM: XNC2_1761(yniC) XNC2_2699(yfbT)
XDO: XDD1_2601(yfbT) XDD1_3622
XPO: XPG1_1349 XPG1_1528(yniC)
PSX: DR96_2757(yniC) DR96_3648
PRG: RB151_018990(yniC) RB151_026780(yfbT)
PHEI: NCTC12003_01549(yfbT) NCTC12003_02357(yniC)
PRJ: NCTC6933_01614(yniC) NCTC6933_02349(yfbT)
ASY: AUT07_00247(yniC)
ANS: ArsFIN_16340(yniC) ArsFIN_26490(yfbT)
LRI: NCTC12151_02310(yfbT)
HAP: HAPS_0179(yniC)
HPAZ: K756_06170
HPAS: JL26_05130
HPAK: JT17_02695
HSO: HS_0674
HSM: HSM_1083
MSU: MS1050
MHT: D648_1220
MHAT: B824_400
MHX: MHH_c06580(yniC)
MHAE: F382_07535
MHAM: J450_07505
MHAO: J451_08435
MHAL: N220_00540
MHAQ: WC39_13525
MHAY: VK67_13530
MVR: X781_600
APL: APL_1213
APJ: APJL_1226
APA: APP7_1264
ASU: Asuc_0616
AIO: EXH44_10860(hxpB)
ADP: NCTC12871_00896(yfbT)
ALIG: NCTC10568_01515(yniC)
BTO: WQG_7770
BTRE: F542_14280
BTRH: F543_15930
BTRA: F544_8120
AVT: NCTC3438_01273(yniC)
PAET: NCTC13378_00613(yniC)
VAG: N646_4036
VNL: D3H41_19590(hxpB)
PPR: PBPRA2175(Z2756)
SALY: E8E00_06995(hxpB)
SKS: FCN78_06415(hxpB)
SCOT: HBA18_06675(hxpB)
PFS: PFLU_4168
PFE: PSF113_2294(yfbT)
PFB: VO64_1247
PMAN: OU5_6025
PANR: A7J50_3848
PSIL: PMA3_10700
SON: SO_0431(yniC)
SDN: Sden_3378
SFR: Sfri_3772
SAZ: Sama_0381
SBL: Sbal_3906
SLO: Shew_3425
SSE: Ssed_0437
SPL: Spea_0424
SHL: Shal_0481
SWD: Swoo_0284
SWP: swp_4741
SVO: SVI_0270
SPSW: Sps_05372
SLJ: EGC82_02990(hxpB)
SMAI: EXU30_11535(hxpB)
SPOL: FH971_18920(hxpB)
SKH: STH12_04079(yniC)
PSEN: PNC201_19830(yfbT)
SALH: HMF8227_02762(yfbT)
FBL: Fbal_0374
FES: HER31_17635(hxpB)
MVS: MVIS_1438
MEJ: Q7A_1748
MEC: Q7C_974
NIK: F5I99_03715(hxpB)
ASR: WL1483_3712(yniC)
ACAV: VI35_10245
ORB: IPMB12_04040(hxpB)
SALN: SALB1_2054
PLG: NCTC10937_01570(yfbT_1)
CABA: SBC2_38690(hxpA_1)
JAG: GJA_1762
CARE: LT85_3092
MLO: mlr4094
MHUA: MCHK_5359
AMIH: CO731_02953(yfbT)
SME: SM_b21214(orf24)
SMER: DU99_29010
SMD: Smed_4703
SFD: USDA257_c11290(yfbT)
ATU: Atu3251
RIR: BN877_II1596(yfbT)
RHT: NT26_2001(yfbT)
SHZ: shn_20780
BME: BMEI1105
BMEL: DK63_308
BMEE: DK62_551
BMF: BAB1_0880
BABO: DK55_872
BABR: DO74_1017
BABT: DK49_630
BABB: DK48_1246
BABU: DK53_856
BABS: DK51_602
BABC: DO78_777
BMS: BR0861
BSZ: DK67_1764
BOV: BOV_0852
BCAR: DK60_919
BCAS: DA85_04095
BMR: BMI_I858
BPP: BPI_I897
BPV: DK65_510
OAN: Oant_2365
OAH: DR92_1825
MOR: MOC_3890
THD: BHV28_05650(yfbT)
CAK: Caul_2162
CSE: Cseg_1615
PDE: Pden_4839
SSAN: NX02_03675
SINB: SIDU_17695
SSI: SSU0684
SUP: YYK_03265
MYO: OEM_44950
MUL: MUL_0545
MMI: MMAR_0580
MSHG: MSG_03286
RER: RER_54450
REY: O5Y_25930
RHB: NY08_87
RHS: A3Q41_04755(yfbT)
TPR: Tpau_3077
SCO: SCO1560(SCL11.16c) SCO2346(SCC8A.04c)
SGR: SGR_5163
SGB: WQO_09555
SCT: SCAT_1450(yfbT) SCAT_5264
SFA: Sfla_4489
SHY: SHJG_3840
SALS: SLNWT_5481
STRP: F750_2202(yfbT)
SFI: SFUL_1923
SALU: DC74_2830
SALL: SAZ_15525
STRM: M444_11845
SRW: TUE45_01979(yfbT_1) TUE45_02936(yfbT_2)
SLE: sle_45840(sle_45840) sle_48500(sle_48500)
SRN: A4G23_01474(yfbT)
SLAU: SLA_1964
SALJ: SMD11_4747
SLX: SLAV_25520(yfbT1) SLAV_35380(yfbT3)
SGE: DWG14_05945(yfbT_1) DWG14_06925(yfbT_2)
LXX: Lxx02170
CMI: CMM_0223
CMS: CMS0789
CMC: CMN_00161
MLV: CVS47_02958(yfbT)
MOY: CVS54_01166(yfbT_1) CVS54_03158(yfbT_2)
ART: Arth_0649
AAU: AAur_0798
JDE: Jden_2195
CFL: Cfla_0403
CFI: Celf_0447
SERJ: SGUI_3174
DCO: SAMEA4475696_0301(yfbT)
PAC: PPA0030
PACC: PAC1_00145
PACH: PAGK_0027
CACN: RN83_00570
CGRN: 4412665_00576(yfbT_1) 4412665_01198(yfbT_2)
PAUS: NCTC13651_02422(yfbT)
ACIJ: JS278_02765(yfbT)
KFL: Kfla_4821
TFU: Tfu_2488
NDA: Ndas_3540
NAL: B005_2979
STRR: EKD16_04770(yfbT1) EKD16_12645(yfbT2)
SRO: Sros_1428
KRA: Krad_1478
SEN: SACE_1848(yfbT)
PDX: Psed_2940
PSEA: WY02_23795
PSEE: FRP1_05045
PSEH: XF36_06930
PAUT: Pdca_18370
AMI: Amir_3098
SESP: BN6_52590
AHG: AHOG_27475(yfbT)
SAQ: Sare_4784
ACTN: L083_6138
AFS: AFR_31435
CWO: Cwoe_3319
CTHE: Chro_3582
FMR: Fuma_01744(yniC)
ACA: ACP_3310(yfbT)
ABAS: ACPOL_1367
TAI: Taci_0546
GBA: J421_0733
MBAS: ALGA_1281
SRU: SRU_2748
SRM: SRM_02959(yfbT)
CPI: Cpin_6618
CHIT: FW415_08785(hxpB)
CHIH: GWR21_12565(hxpB)
ARK: D6B99_04990(hxpB)
AGI: FSB73_02640(hxpB)
ARAC: E0W69_012180(hxpB)
PSEG: D3H65_14535(hxpB)
PGIN: FRZ67_21080(hxpB)
FLS: GLV81_04385(hxpB)
LACS: H4075_08210(hxpB)
SPDR: G6053_17620(hxpB)
SDJ: NCTC13534_03153(yqaB_1)
DFE: Dfer_4825
SLI: Slin_2846
SPIK: EXU85_19425(hxpB)
SPIB: G8759_31610(hxpB)
LBY: Lbys_0379
FJO: Fjoh_2690
MPW: MPR_0422
CHZ: CHSO_2113
CNK: EG343_24550(hxpB)
CLAC: EG342_15610(hxpB)
 » show all
Reference
1  [PMID:16663332]
  Authors
Rumpho ME, Edwards GE, Loescher WH.
  Title
A Pathway for Photosynthetic Carbon Flow to Mannitol in Celery Leaves : Activity and Localization of Key Enzymes.
  Journal
Plant Physiol 73:869-873 (1983)
DOI:10.1104/pp.73.4.869
Reference
2  [PMID:13787089]
  Authors
YAMADA H, OKAMOTO K, KODAMA K, NOGUCHI F, TANAKA S.
  Title
Enzymatic studies on mannitol formation by Piricularia oryzae.
  Journal
J Biochem 49:404-10 (1961)
DOI:10.1093/oxfordjournals.jbchem.a127317
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.22
IUBMB Enzyme Nomenclature: 3.1.3.22
ExPASy - ENZYME nomenclature database: 3.1.3.22
BRENDA, the Enzyme Database: 3.1.3.22
CAS: 9055-29-2

KEGG   REACTION: R02167
Entry
R02167                      Reaction                               

Name
D-Mannitol-1-phosphate phosphohydrolase
Definition
D-Mannitol 1-phosphate + H2O <=> Mannitol + Orthophosphate
Equation
Reaction class
RC00017  C00392_C00644
Enzyme
Pathway
rn00051  Fructose and mannose metabolism
rn01100  Metabolic pathways
Orthology
K19270  mannitol-1-/sugar-/sorbitol-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50]
K24204  mannitol-1-/sugar-/sorbitol-6-/2-deoxyglucose-6-phosphatase [EC:3.1.3.22 3.1.3.23 3.1.3.50 3.1.3.68]
Other DBs
RHEA: 19540

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