KEGG ORTHOLOGY: K19663

ORTHOLOGY: K19663

Entry

K19663                      KO

Symbol

PRKCG

Name

classical protein kinase C gamma type [EC:2.7.11.13]

Pathway

map01521

EGFR tyrosine kinase inhibitor resistance

map04010

MAPK signaling pathway

map04012

ErbB signaling pathway

map04014

Ras signaling pathway

map04015

Rap1 signaling pathway

map04020

Calcium signaling pathway

map04066

HIF-1 signaling pathway

map04070

Phosphatidylinositol signaling system

map04071

Sphingolipid signaling pathway

map04150

mTOR signaling pathway

map04270

Vascular smooth muscle contraction

map04310

Wnt signaling pathway

map04370

VEGF signaling pathway

map04510

Focal adhesion

map04540

Gap junction

map04613

Neutrophil extracellular trap formation

map04650

Natural killer cell mediated cytotoxicity

map04666

Fc gamma R-mediated phagocytosis

map04670

Leukocyte transendothelial migration

map04713

Circadian entrainment

map04720

Long-term potentiation

map04723

Retrograde endocannabinoid signaling

map04724

Glutamatergic synapse

map04725

Cholinergic synapse

map04726

Serotonergic synapse

map04727

GABAergic synapse

map04728

Dopaminergic synapse

map04730

Long-term depression

map04750

Inflammatory mediator regulation of TRP channels

map04911

Insulin secretion

map04916

Melanogenesis

map04918

Thyroid hormone synthesis

map04919

Thyroid hormone signaling pathway

map04921

Oxytocin signaling pathway

map04925

Aldosterone synthesis and secretion

map04928

Parathyroid hormone synthesis, secretion and action

map04929

GnRH secretion

map04935

Growth hormone synthesis, secretion and action

map04960

Aldosterone-regulated sodium reabsorption

map04961

Endocrine and other factor-regulated calcium reabsorption

map04970

Salivary secretion

map04971

Gastric acid secretion

map04972

Pancreatic secretion

map05017

Spinocerebellar ataxia

map05022

Pathways of neurodegeneration - multiple diseases

map05031

Amphetamine addiction

map05032

Morphine addiction

map05143

African trypanosomiasis

map05146

Amoebiasis

map05161

Hepatitis B

map05163

Human cytomegalovirus infection

map05170

Human immunodeficiency virus 1 infection

map05171

Coronavirus disease - COVID-19

map05200

Pathways in cancer

map05205

Proteoglycans in cancer

map05206

MicroRNAs in cancer

map05207

Chemical carcinogenesis - receptor activation

map05214

Glioma

map05223

Non-small cell lung cancer

map05225

Hepatocellular carcinoma

map05231

Choline metabolism in cancer

map05415

Diabetic cardiomyopathy

Disease

H00063

Spinocerebellar ataxia (SCA)

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04012 ErbB signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04014 Ras signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04015 Rap1 signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04310 Wnt signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04370 VEGF signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04066 HIF-1 signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04020 Calcium signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04070 Phosphatidylinositol signaling system
    K19663  PRKCG; classical protein kinase C gamma type
   04071 Sphingolipid signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04150 mTOR signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K19663  PRKCG; classical protein kinase C gamma type
   04540 Gap junction
    K19663  PRKCG; classical protein kinase C gamma type
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K19663  PRKCG; classical protein kinase C gamma type
   04650 Natural killer cell mediated cytotoxicity
    K19663  PRKCG; classical protein kinase C gamma type
   04666 Fc gamma R-mediated phagocytosis
    K19663  PRKCG; classical protein kinase C gamma type
   04670 Leukocyte transendothelial migration
    K19663  PRKCG; classical protein kinase C gamma type
  09152 Endocrine system
   04911 Insulin secretion
    K19663  PRKCG; classical protein kinase C gamma type
   04929 GnRH secretion
    K19663  PRKCG; classical protein kinase C gamma type
   04921 Oxytocin signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04935 Growth hormone synthesis, secretion and action
    K19663  PRKCG; classical protein kinase C gamma type
   04918 Thyroid hormone synthesis
    K19663  PRKCG; classical protein kinase C gamma type
   04919 Thyroid hormone signaling pathway
    K19663  PRKCG; classical protein kinase C gamma type
   04928 Parathyroid hormone synthesis, secretion and action
    K19663  PRKCG; classical protein kinase C gamma type
   04916 Melanogenesis
    K19663  PRKCG; classical protein kinase C gamma type
   04925 Aldosterone synthesis and secretion
    K19663  PRKCG; classical protein kinase C gamma type
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K19663  PRKCG; classical protein kinase C gamma type
  09154 Digestive system
   04970 Salivary secretion
    K19663  PRKCG; classical protein kinase C gamma type
   04971 Gastric acid secretion
    K19663  PRKCG; classical protein kinase C gamma type
   04972 Pancreatic secretion
    K19663  PRKCG; classical protein kinase C gamma type
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K19663  PRKCG; classical protein kinase C gamma type
   04961 Endocrine and other factor-regulated calcium reabsorption
    K19663  PRKCG; classical protein kinase C gamma type
  09156 Nervous system
   04724 Glutamatergic synapse
    K19663  PRKCG; classical protein kinase C gamma type
   04727 GABAergic synapse
    K19663  PRKCG; classical protein kinase C gamma type
   04725 Cholinergic synapse
    K19663  PRKCG; classical protein kinase C gamma type
   04728 Dopaminergic synapse
    K19663  PRKCG; classical protein kinase C gamma type
   04726 Serotonergic synapse
    K19663  PRKCG; classical protein kinase C gamma type
   04720 Long-term potentiation
    K19663  PRKCG; classical protein kinase C gamma type
   04730 Long-term depression
    K19663  PRKCG; classical protein kinase C gamma type
   04723 Retrograde endocannabinoid signaling
    K19663  PRKCG; classical protein kinase C gamma type
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K19663  PRKCG; classical protein kinase C gamma type
  09159 Environmental adaptation
   04713 Circadian entrainment
    K19663  PRKCG; classical protein kinase C gamma type
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K19663  PRKCG; classical protein kinase C gamma type
   05206 MicroRNAs in cancer
    K19663  PRKCG; classical protein kinase C gamma type
   05205 Proteoglycans in cancer
    K19663  PRKCG; classical protein kinase C gamma type
   05207 Chemical carcinogenesis - receptor activation
    K19663  PRKCG; classical protein kinase C gamma type
   05231 Choline metabolism in cancer
    K19663  PRKCG; classical protein kinase C gamma type
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K19663  PRKCG; classical protein kinase C gamma type
   05214 Glioma
    K19663  PRKCG; classical protein kinase C gamma type
   05223 Non-small cell lung cancer
    K19663  PRKCG; classical protein kinase C gamma type
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K19663  PRKCG; classical protein kinase C gamma type
   05161 Hepatitis B
    K19663  PRKCG; classical protein kinase C gamma type
   05171 Coronavirus disease - COVID-19
    K19663  PRKCG; classical protein kinase C gamma type
   05163 Human cytomegalovirus infection
    K19663  PRKCG; classical protein kinase C gamma type
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K19663  PRKCG; classical protein kinase C gamma type
   05143 African trypanosomiasis
    K19663  PRKCG; classical protein kinase C gamma type
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K19663  PRKCG; classical protein kinase C gamma type
   05022 Pathways of neurodegeneration - multiple diseases
    K19663  PRKCG; classical protein kinase C gamma type
  09165 Substance dependence
   05031 Amphetamine addiction
    K19663  PRKCG; classical protein kinase C gamma type
   05032 Morphine addiction
    K19663  PRKCG; classical protein kinase C gamma type
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K19663  PRKCG; classical protein kinase C gamma type
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K19663  PRKCG; classical protein kinase C gamma type
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K19663  PRKCG; classical protein kinase C gamma type
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     K19663  PRKCG; classical protein kinase C gamma type
Protein kinases [BR:ko01001]
Serine/threonine kinases: AGC group
  PKC family [OT]
   K19663  PRKCG; classical protein kinase C gamma type

Other DBs

GO:

0004697

Genes

HSA:	5582(PRKCG)

PTR:	456276(PRKCG)

PPS:	100990245(PRKCG)

GGO:	101139074(PRKCG)

PON:	100451563(PRKCG)

PPYG:

129019849(PRKCG)

NLE:	100601464(PRKCG)

HMH:	116479165(PRKCG)

SSYN:

129460671(PRKCG)

MCC:	720263(PRKCG)

MCF:	101865773(PRKCG)

MTHB:

126943319

MNI:	105497021(PRKCG)

CSAB:

103235232(PRKCG)

CATY:

105595654(PRKCG)

PANU:

100137333(PRKCG)

TGE:	112613317(PRKCG)

MLEU:

105539692(PRKCG)

RRO:	104676027(PRKCG)

RBB:	108529452(PRKCG)

TFN:	117091710(PRKCG)

PTEH:

111530493(PRKCG)

CANG:

105524211(PRKCG)

CJC:	100404028(PRKCG)

SBQ:	101032613(PRKCG)

CIMI:

108282129(PRKCG)

ANAN:

105732524(PRKCG)

CSYR:

103276479(PRKCG)

MMUR:

105874723(PRKCG)

LCAT:

123624654(PRKCG)

PCOQ:

105809569(PRKCG)

OGA:	100956877(PRKCG)

MMU:	18752(Prkcg)

MCAL:

110297763(Prkcg)

MPAH:

110336366(Prkcg)

RNO:	24681(Prkcg)

MCOC:

116101512(Prkcg)

ANU:	117701003(Prkcg)

MUN:	110556016(Prkcg)

CGE:	100762950(Prkcg)

MAUA:

101828136(Prkcg)

PROB:

127238613(Prkcg)

PLEU:

114687523(Prkcg)

MORG:

121449728(Prkcg)

MFOT:

126493096

AAMP:

119820784(Prkcg)

NGI:	103729666(Prkcg)

HGL:	101698346(Prkcg)

CPOC:

100733947(Prkcg)

CCAN:

109693140(Prkcg)

DORD:

105994311(Prkcg)

DSP:	122110671(Prkcg)

PLOP:

125338673(Prkcg)

NCAR:

124967611

MMMA:

107158898(Prkcg)

OCU:	100009102(PRKCG)

OPI:	101534827(PRKCG)

TUP:	102497204(PRKCG)

GVR:	103583388 103599669(PRKCG)

CFA:	100855828(PRKCG)

CLUD:

112645036(PRKCG)

VVP:	112909321(PRKCG)

VLG:	121480810(PRKCG)

NPO:	129500385(PRKCG)

AML:	100484719(PRKCG)

UMR:	103672914(PRKCG)

UAH:	113247385(PRKCG)

UAR:	123786995(PRKCG)

ELK:

111139613

LLV:

125089171

MPUF:

101671536(PRKCG)

MNP:	132004993(PRKCG)

MLK:	131818861(PRKCG)

NVS:	122911685(PRKCG)

ORO:	101363254(PRKCG)

EJU:	114201798(PRKCG)

ZCA:	113935801(PRKCG)

MLX:	117997993(PRKCG)

NSU:	110573626(PRKCG)

LWW:	102741890(PRKCG)

FCA:	101082196(PRKCG)

PYU:	121018827(PRKCG)

PCOO:

112850908(PRKCG)

PBG:	122494748(PRKCG)

PVIV:

125153700(PRKCG)

LRUF:

124527789

PTG:	102956490(PRKCG)

PPAD:

109259277(PRKCG)

PUC:

125915497

AJU:

106980855

HHV:	120239766(PRKCG)

BTA:	282002(PRKCG)

BOM:	102265831(PRKCG)

BIU:	109572998(PRKCG)

BBUB:

102397646(PRKCG)

BBIS:

105000236(PRKCG)

CHX:	102175984(PRKCG)

OAS:	101116423(PRKCG)

BTAX:

128063096(PRKCG)

ODA:	120871941(PRKCG)

CCAD:

122420171(PRKCG)

MBEZ:

129546400(PRKCG)

SSC:	100518074(PRKCG)

CFR:	102513516(PRKCG)

CBAI:

105074322(PRKCG)

CDK:	105103265(PRKCG)

VPC:	102542323(PRKCG)

BACU:

103017540(PRKCG)

BMUS:

118884764(PRKCG)

LVE:	103086653(PRKCG)

OOR:	101276418(PRKCG)

DLE:	111180981(PRKCG)

PCAD:

102983841(PRKCG)

PSIU:

116743766(PRKCG)

NASI:

112397907(PRKCG)

ECB:	100062549(PRKCG)

EPZ:	103556196(PRKCG)

EAI:	106840859(PRKCG)

MYB:	102249897(PRKCG)

MYD:	102756030(PRKCG)

MMYO:

118660957(PRKCG)

MLF:

102419083

MDT:	132216549(PRKCG)

PKL:	118719731(PRKCG)

EFUS:

103303678(PRKCG)

MNA:	107540426(PRKCG)

DRO:	112321262(PRKCG)

SHON:

118986634(PRKCG)

AJM:	119036009(PRKCG)

PDIC:

114511158(PRKCG)

PHAS:

123824140(PRKCG)

MMF:	118638191(PRKCG)

PPAM:

129081586(PRKCG)

HAI:	109372505(PRKCG)

RFQ:	117035150(PRKCG)

PALE:

102888961(PRKCG)

PGIG:

120616484(PRKCG)

PVP:	105309462(PRKCG)

RAY:	107503061(PRKCG)

MJV:	108395733(PRKCG)

TOD:	119249714(PRKCG)

SARA:

101539279(PRKCG)

SETR:

126027978(PRKCG)

LAV:	100671733(PRKCG)

TMU:

101351254

ETF:	101651846(PRKCG)

DNM:	101447351(PRKCG)

GAS:	123254168 123255143

SHR:	100935225(PRKCG)

AFZ:

127556522

PCW:	110220182(PRKCG)

TVP:	118839200(PRKCG)

OAA:	100085442(PRKCG)

CJO:

ACYG:

GFR:

PHI:

FPG:	101910888(CACNG7)

FCH:

102049511

SHAB:

115602904(PRKCG)

CUCA:

104064246(PRKCG)

RTD:

128903859

ASN:	102371860(PRKCG)

AMJ:	102574559(PRKCG)

PSS:

102459783

CMY:	102932331(PRKCG)

CCAY:

125627876(PRKCG)

DCC:	119847377(PRKCG)

CPIC:

101937053(PRKCG)

TST:	117870501(PRKCG)

CABI:

116832380

MRV:	120388263(PRKCG)

ACS:	100559682(prkcg)

ASAO:

132777885(PRKCG)

PVT:	110078510(PRKCG)

SUND:

121932615(PRKCG)

PBI:	103055466(PRKCG)

PMUR:

107282442 107288141

CTIG:

120304480(PRKCG)

TSR:	106538053(PRKCG)

PGUT:

117666672(PRKCG)

APRI:

131198774(PRKCG)

PTEX:

113443569(PRKCG)

NSS:	113418514(PRKCG)

VKO:	123032105(PRKCG)

PMUA:

114581744(PRKCG)

PRAF:

128399462(PRKCG)

ZVI:	118094978(PRKCG)

HCG:	128329341(PRKCG)

GJA:	107113125(PRKCG)

STOW:

125444571(PRKCG)

EMC:	129338720(PRKCG)

XLA:	108696776 108697820

XTR:	100496779(prkcg)

NPR:	108797498(PRKCG)

RTEM:

120915291(PRKCG)

BBUF:

121003127(PRKCG)

BGAR:

122926643(PRKCG)

MUO:	115466532(PRKCG)

GSH:	117368368(PRKCG)

DRE:	100003514(prkcg)

SANH:

107672989 107692563

SGH:	107549470 107598407

CAUA:

113059935 113116357

CGIB:

127974293 128029992

LROH:

127178761(prkcg)

OMC:	131521212(prkcg)

PPRM:

120484709(prkcg)

RKG:	130103639(prkcg)

MAMB:

125242974(prkcg)

CIDE:

127497283

CERY:

137025670(prkcg)

MASI:

127453517 127453734

TROS:

130557446(prkcg)

TDW:	130433482(prkcg)

MANU:

129447854(prkcg)

IPU:	108266582(prkcg)

IFU:	128608413(prkcg)

PHYP:

113542453

SMEO:

124384840(prkcg)

TFD:	113643727(prkcg)

TVC:	132845349(prkcg)

TRN:	134310216(prkcg)

AMEX:

103042824(prkcg)

CMAO:

118824989(prkcg)

CHAR:

105894611(prkcg)

TRU:

101079823

TFS:	130532931(prkcg)

TNG:	GSTEN00015420G001

LCO:

104929793

NCC:

104960432

TBEN:

117480431(prkcg)

CGOB:

115021190

PGEO:

117461588(prkcg)

GACU:

117543213(prkcg)

EMAC:

134861768(prkcg)

ELY:	117265709(prkcg)

EFO:	125893640(prkcg)

PLEP:

121945942(prkcg)

SLUC:

116049652(prkcg)

ECRA:

117946209(prkcg)

ESP:

116691362

PFLV:

114557331

GAT:	120809973(prkcg)

PPUG:

119198242(prkcg)

AFB:	129109298(prkcg)

CLUM:

117745270(prkcg)

PSWI:

130213123(prkcg)

MSAM:

119897496(prkcg)

SCHU:

122882022(prkcg)

CUD:	121513601(prkcg)

ALAT:

119006482(prkcg)

MZE:

101481445

ONL:

100699493

OAU:	116323881(prkcg)

OLA:

101164921

OML:	112143416(prkcg)

CSAI:

133433875(prkcg)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122830524(prkcg)

PPRL:

129371521(prkcg)

CVG:

107100308

CTUL:

119782956(prkcg)

GMU:	124866124(prkcg)

NFU:

107379571

KMR:	108235495(prkcg)

ALIM:

106520517

NWH:	119409381(prkcg)

AOCE:

111569071

MCEP:

125015974(prkcg)

CSEM:

103387841

POV:

109633056

SSEN:

122774138(prkcg)

HHIP:

117777363(prkcg)

HSP:	118113177(prkcg)

PPLT:

128449406(prkcg)

SMAU:

118314827(prkcg)

LCF:	108887298(prkcg)

SDU:

111230118

SLAL:

111669824

XGL:	120784226(prkcg)

HCQ:

109515431

SSCV:

125975667

SBIA:

133501023(prkcg)

PEE:	133401470(prkcg)

PTAO:

133480082(prkcg)

BPEC:

110163020

MALB:

109970170

BSPL:

114843025(prkcg)

SJO:	128365943(prkcg)

OTW:	112239941 112240612

OMY:	110512786 118945770(prkcg)

OGO:

124005945

OKI:

109886787

OKE:	118379399 127914344

SNH:

CCLU:

ELS:

SFM:

PKI:

AANG:

118221921(prkcg)

PSPA:

121302494(prkcg)

ARUT:

117409942 117966808

PSEX:

120518916

LCM:	102352260(PRKCG)

SCLV:

120333729

» show all

Reference

PMID:12417016

Authors

Saito N, Shirai Y

Title

Protein kinase C gamma (PKC gamma): function of neuron specific isotype.

Journal

J Biochem 132:683-7 (2002)
DOI:10.1093/oxfordjournals.jbchem.a003274

Sequence

[hsa:5582]

Reference

PMID:3755548

Authors

Coussens L, Parker PJ, Rhee L, Yang-Feng TL, Chen E, Waterfield MD, Francke U, Ullrich A

Title

Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.

Journal

Science 233:859-66 (1986)
DOI:10.1126/science.3755548

Sequence

[hsa:5582]

ORTHOLOGY: K19662

Entry

K19662                      KO

Symbol

PRKCB

Name

classical protein kinase C beta type [EC:2.7.11.13]

Pathway

map01521

EGFR tyrosine kinase inhibitor resistance

map04010

MAPK signaling pathway

map04012

ErbB signaling pathway

map04014

Ras signaling pathway

map04015

Rap1 signaling pathway

map04020

Calcium signaling pathway

map04062

Chemokine signaling pathway

map04064

NF-kappa B signaling pathway

map04066

HIF-1 signaling pathway

map04070

Phosphatidylinositol signaling system

map04071

Sphingolipid signaling pathway

map04150

mTOR signaling pathway

map04270

Vascular smooth muscle contraction

map04310

Wnt signaling pathway

map04370

VEGF signaling pathway

map04510

Focal adhesion

map04540

Gap junction

map04613

Neutrophil extracellular trap formation

map04650

Natural killer cell mediated cytotoxicity

map04662

B cell receptor signaling pathway

map04666

Fc gamma R-mediated phagocytosis

map04670

Leukocyte transendothelial migration

map04713

Circadian entrainment

map04720

Long-term potentiation

map04723

Retrograde endocannabinoid signaling

map04724

Glutamatergic synapse

map04725

Cholinergic synapse

map04726

Serotonergic synapse

map04727

GABAergic synapse

map04728

Dopaminergic synapse

map04730

Long-term depression

map04750

Inflammatory mediator regulation of TRP channels

map04911

Insulin secretion

map04912

GnRH signaling pathway

map04916

Melanogenesis

map04918

Thyroid hormone synthesis

map04919

Thyroid hormone signaling pathway

map04921

Oxytocin signaling pathway

map04925

Aldosterone synthesis and secretion

map04928

Parathyroid hormone synthesis, secretion and action

map04929

GnRH secretion

map04931

Insulin resistance

map04933

AGE-RAGE signaling pathway in diabetic complications

map04935

Growth hormone synthesis, secretion and action

map04960

Aldosterone-regulated sodium reabsorption

map04961

Endocrine and other factor-regulated calcium reabsorption

map04970

Salivary secretion

map04971

Gastric acid secretion

map04972

Pancreatic secretion

map04973

Carbohydrate digestion and absorption

map05017

Spinocerebellar ataxia

map05022

Pathways of neurodegeneration - multiple diseases

map05031

Amphetamine addiction

map05032

Morphine addiction

map05140

Leishmaniasis

map05143

African trypanosomiasis

map05146

Amoebiasis

map05161

Hepatitis B

map05163

Human cytomegalovirus infection

map05164

Influenza A

map05170

Human immunodeficiency virus 1 infection

map05171

Coronavirus disease - COVID-19

map05200

Pathways in cancer

map05205

Proteoglycans in cancer

map05206

MicroRNAs in cancer

map05207

Chemical carcinogenesis - receptor activation

map05214

Glioma

map05223

Non-small cell lung cancer

map05225

Hepatocellular carcinoma

map05231

Choline metabolism in cancer

map05415

Diabetic cardiomyopathy

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04012 ErbB signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04014 Ras signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04015 Rap1 signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04310 Wnt signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04370 VEGF signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04064 NF-kappa B signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04066 HIF-1 signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04020 Calcium signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04070 Phosphatidylinositol signaling system
    K19662  PRKCB; classical protein kinase C beta type
   04071 Sphingolipid signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04150 mTOR signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K19662  PRKCB; classical protein kinase C beta type
   04540 Gap junction
    K19662  PRKCB; classical protein kinase C beta type
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K19662  PRKCB; classical protein kinase C beta type
   04650 Natural killer cell mediated cytotoxicity
    K19662  PRKCB; classical protein kinase C beta type
   04662 B cell receptor signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04666 Fc gamma R-mediated phagocytosis
    K19662  PRKCB; classical protein kinase C beta type
   04670 Leukocyte transendothelial migration
    K19662  PRKCB; classical protein kinase C beta type
   04062 Chemokine signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
  09152 Endocrine system
   04911 Insulin secretion
    K19662  PRKCB; classical protein kinase C beta type
   04929 GnRH secretion
    K19662  PRKCB; classical protein kinase C beta type
   04912 GnRH signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04921 Oxytocin signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04935 Growth hormone synthesis, secretion and action
    K19662  PRKCB; classical protein kinase C beta type
   04918 Thyroid hormone synthesis
    K19662  PRKCB; classical protein kinase C beta type
   04919 Thyroid hormone signaling pathway
    K19662  PRKCB; classical protein kinase C beta type
   04928 Parathyroid hormone synthesis, secretion and action
    K19662  PRKCB; classical protein kinase C beta type
   04916 Melanogenesis
    K19662  PRKCB; classical protein kinase C beta type
   04925 Aldosterone synthesis and secretion
    K19662  PRKCB; classical protein kinase C beta type
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    K19662  PRKCB; classical protein kinase C beta type
  09154 Digestive system
   04970 Salivary secretion
    K19662  PRKCB; classical protein kinase C beta type
   04971 Gastric acid secretion
    K19662  PRKCB; classical protein kinase C beta type
   04972 Pancreatic secretion
    K19662  PRKCB; classical protein kinase C beta type
   04973 Carbohydrate digestion and absorption
    K19662  PRKCB; classical protein kinase C beta type
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K19662  PRKCB; classical protein kinase C beta type
   04961 Endocrine and other factor-regulated calcium reabsorption
    K19662  PRKCB; classical protein kinase C beta type
  09156 Nervous system
   04724 Glutamatergic synapse
    K19662  PRKCB; classical protein kinase C beta type
   04727 GABAergic synapse
    K19662  PRKCB; classical protein kinase C beta type
   04725 Cholinergic synapse
    K19662  PRKCB; classical protein kinase C beta type
   04728 Dopaminergic synapse
    K19662  PRKCB; classical protein kinase C beta type
   04726 Serotonergic synapse
    K19662  PRKCB; classical protein kinase C beta type
   04720 Long-term potentiation
    K19662  PRKCB; classical protein kinase C beta type
   04730 Long-term depression
    K19662  PRKCB; classical protein kinase C beta type
   04723 Retrograde endocannabinoid signaling
    K19662  PRKCB; classical protein kinase C beta type
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    K19662  PRKCB; classical protein kinase C beta type
  09159 Environmental adaptation
   04713 Circadian entrainment
    K19662  PRKCB; classical protein kinase C beta type
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K19662  PRKCB; classical protein kinase C beta type
   05206 MicroRNAs in cancer
    K19662  PRKCB; classical protein kinase C beta type
   05205 Proteoglycans in cancer
    K19662  PRKCB; classical protein kinase C beta type
   05207 Chemical carcinogenesis - receptor activation
    K19662  PRKCB; classical protein kinase C beta type
   05231 Choline metabolism in cancer
    K19662  PRKCB; classical protein kinase C beta type
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K19662  PRKCB; classical protein kinase C beta type
   05214 Glioma
    K19662  PRKCB; classical protein kinase C beta type
   05223 Non-small cell lung cancer
    K19662  PRKCB; classical protein kinase C beta type
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K19662  PRKCB; classical protein kinase C beta type
   05161 Hepatitis B
    K19662  PRKCB; classical protein kinase C beta type
   05171 Coronavirus disease - COVID-19
    K19662  PRKCB; classical protein kinase C beta type
   05164 Influenza A
    K19662  PRKCB; classical protein kinase C beta type
   05163 Human cytomegalovirus infection
    K19662  PRKCB; classical protein kinase C beta type
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K19662  PRKCB; classical protein kinase C beta type
   05140 Leishmaniasis
    K19662  PRKCB; classical protein kinase C beta type
   05143 African trypanosomiasis
    K19662  PRKCB; classical protein kinase C beta type
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K19662  PRKCB; classical protein kinase C beta type
   05022 Pathways of neurodegeneration - multiple diseases
    K19662  PRKCB; classical protein kinase C beta type
  09165 Substance dependence
   05031 Amphetamine addiction
    K19662  PRKCB; classical protein kinase C beta type
   05032 Morphine addiction
    K19662  PRKCB; classical protein kinase C beta type
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K19662  PRKCB; classical protein kinase C beta type
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K19662  PRKCB; classical protein kinase C beta type
   04933 AGE-RAGE signaling pathway in diabetic complications
    K19662  PRKCB; classical protein kinase C beta type
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K19662  PRKCB; classical protein kinase C beta type
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K19662  PRKCB; classical protein kinase C beta type
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     K19662  PRKCB; classical protein kinase C beta type
Protein kinases [BR:ko01001]
Serine/threonine kinases: AGC group
  PKC family [OT]
   K19662  PRKCB; classical protein kinase C beta type

Other DBs

GO:

0004697

Genes

HSA:	5579(PRKCB)

PTR:	453993(PRKCB)

PPS:	100970296(PRKCB)

GGO:	101150691(PRKCB)

PON:	100439900(PRKCB)

PPYG:

129015694(PRKCB)

NLE:	100590939(PRKCB)

HMH:	116471147(PRKCB)

SSYN:

129457513(PRKCB)

MCC:	701195(PRKCB)

MCF:	102116992(PRKCB)

MTHB:

126944386

MNI:	105485029(PRKCB)

CSAB:

103229829(PRKCB)

CATY:

105586076(PRKCB)

PANU:

101009865(PRKCB)

TGE:	112614190(PRKCB)

MLEU:

105545146(PRKCB)

RRO:	104665907(PRKCB)

RBB:	108538857(PRKCB)

TFN:	117087485(PRKCB)

PTEH:

111524197(PRKCB)

CANG:

105523456(PRKCB)

CJC:	100410136(PRKCB)

SBQ:	101039384(PRKCB)

CIMI:

108308532(PRKCB)

ANAN:

105725611(PRKCB)

CSYR:

103251444(PRKCB)

MMUR:

105879718(PRKCB)

LCAT:

123632490(PRKCB)

PCOQ:

105810946(PRKCB)

OGA:	100943579(PRKCB)

MMU:	18751(Prkcb)

MCAL:

110297826(Prkcb)

MPAH:

110320075(Prkcb)

RNO:	25023(Prkcb)

MCOC:

116102917(Prkcb)

ANU:	117717067(Prkcb)

MUN:	110559612(Prkcb)

CGE:	100760922(Prkcb)

MAUA:

101824743(Prkcb)

PROB:

127228289(Prkcb)

PLEU:

114692203(Prkcb)

MORG:

121458065(Prkcb)

MFOT:

126502354

AAMP:

119822917(Prkcb)

NGI:	103746928(Prkcb)

HGL:	101722702(Prkcb)

CPOC:

100717697(Prkcb)

CCAN:

109683738(Prkcb)

DORD:

105981822(Prkcb)

DSP:	122116145(Prkcb)

PLOP:

125340531(Prkcb)

NCAR:

124970211

MMMA:

107146552(Prkcb)

OCU:	100037719(PRKCB)

OPI:	101523439(PRKCB)

TUP:	102469271(PRKCB)

GVR:	103592574(PRKCB)

CFA:	489968(PRKCB)

CLUD:

112640230(PRKCB)

VVP:	112908300(PRKCB)

VLG:	121487652(PRKCB)

NPO:	129519978(PRKCB)

AML:	100478007(PRKCB)

UMR:	103668895(PRKCB)

UAH:	113267584(PRKCB)

UAR:	123778823(PRKCB)

ELK:

111162208

LLV:

125090366

MPUF:

101680372(PRKCB)

MNP:	132026832(PRKCB)

MLK:	131819600(PRKCB)

NVS:	122895627(PRKCB)

ORO:	101380879(PRKCB)

EJU:	114198767(PRKCB) 114202995 114202996

ZCA:	113932280(PRKCB)

MLX:	117999123(PRKCB)

NSU:	110577506(PRKCB)

LWW:	102732903(PRKCB)

FCA:	101088970(PRKCB)

PYU:	121019369(PRKCB)

PCOO:

112853117(PRKCB)

PBG:	122471545(PRKCB)

PVIV:

125154310(PRKCB)

LRUF:

124517730

PTG:	102952814(PRKCB)

PPAD:

109255537(PRKCB)

PUC:

125927972

AJU:

106970449

HHV:	120233260(PRKCB)

BTA:	282325(PRKCB)

BOM:	102274116(PRKCB)

BIU:	109578560(PRKCB)

BBUB:

102407189(PRKCB)

BBIS:

104986737(PRKCB)

CHX:	102172114(PRKCB)

OAS:	101118410(PRKCB)

BTAX:

128066420(PRKCB)

ODA:	120876193(PRKCB)

CCAD:

122433081(PRKCB)

MBEZ:

129545462(PRKCB)

SSC:	100522792(PRKCB)

CFR:	102511859(PRKCB)

CBAI:

105073669(PRKCB)

CDK:	105094833(PRKCB)

VPC:	102526158(PRKCB)

BACU:

103012542(PRKCB)

BMUS:

118881786(PRKCB)

LVE:	103090549(PRKCB)

OOR:	101277002(PRKCB)

DLE:	111182232(PRKCB)

PCAD:

102974383(PRKCB)

PSIU:

116739537(PRKCB)

NASI:

112399411(PRKCB)

ECB:	100069215(PRKCB)

EPZ:	103558165(PRKCB)

EAI:	106823831(PRKCB)

MYB:	102243136(PRKCB)

MYD:	102757004(PRKCB)

MMYO:

118655815(PRKCB)

MLF:	102428240(PRKCB)

MDT:	132232673(PRKCB)

PKL:	118731558(PRKCB)

EFUS:

103296210(PRKCB)

MNA:	107544745(PRKCB)

DRO:	112304830(PRKCB)

SHON:

119004000(PRKCB)

AJM:	119043241(PRKCB)

PDIC:

114494685(PRKCB)

PHAS:

123825494(PRKCB)

MMF:	118641370(PRKCB)

PPAM:

129076731(PRKCB)

HAI:	109386578(PRKCB)

RFQ:	117019414(PRKCB)

PALE:

102880663(PRKCB)

PGIG:

120584534(PRKCB)

PVP:

105308818

RAY:	107516091(PRKCB)

MJV:	108385666(PRKCB)

TOD:	119241818(PRKCB)

SARA:

101547658(PRKCB)

SETR:

126030861(PRKCB)

LAV:	100672078(PRKCB)

TMU:

101356454

ETF:	101657103(PRKCB)

DNM:	101421680(PRKCB)

MDO:	100013346(PRKCB)

GAS:	123231861(PRKCB)

SHR:	100924022(PRKCB)

AFZ:

127541963

PCW:	110214622(PRKCB)

TVP:	118831716(PRKCB)

OAA:	100074181(PRKCB)

GGA:	416567(PRKCB)

PCOC:

116237359(PRKCB)

MGP:	100538953(PRKCB)

CJO:	107320755(PRKCB)

TPAI:

128078963(PRKCB)

LMUT:

125700557(PRKCB)

NMEL:

110405777(PRKCB)

APLA:

101799551(PRKCB)

ACYG:

106046027(PRKCB)

CATA:

118256461(PRKCB)

AFUL:

116495441(PRKCB)

TGU:	100227442(PRKCB)

LSR:	110479547(PRKCB)

SCAN:

103817801(PRKCB)

PMOA:

120513152(PRKCB)

OTC:	121334557(PRKCB)

PRUF:

121365824(PRKCB)

GFR:	102041922(PRKCB)

FAB:	101820883(PRKCB)

OMA:	130259297(PRKCB)

PHI:	102104824(PRKCB)

PMAJ:

107211235(PRKCB)

CCAE:

111936199(PRKCB)

CCW:	104684988(PRKCB)

CBRC:

103615516(PRKCB)

ETL:	114064309(PRKCB)

ZAB:	102065127(PRKCB)

ZLE:	135454306(PRKCB)

ACHL:

103803878

SVG:	106859275(PRKCB)

MMEA:

130576489(PRKCB)

HRT:	120759616(PRKCB)

SATI:

136368019(PRKCB)

FPG:	101912011(PRKCB)

FCH:	102047370(PRKCB)

NNT:

104405779

SHAB:

115606584(PRKCB)

ACUN:

113485934(PRKCB)

TALA:

116961357(PRKCB)

ACHC:

115335844(PRKCB)

HLE:	104833745(PRKCB)

AGEN:

GCL:

CSTI:

MNB:

DPUB:

104300281(PRKCB)

AVIT:

104276755

EGZ:	104134542(PRKCB)

NNI:	104015276(PRKCB)

PADL:

103921911(PRKCB)

AFOR:

103905056(PRKCB)

CLV:	102090291(PRKCB)

EHS:

104514535

CUCA:

104065068(PRKCB)

TEO:

104384465

OHA:

104336128

ACAR:

104526692

CPEA:

104393133(PRKCB)

CVF:	104295377(PRKCB)

RTD:	128913847(PRKCB)

AAM:	106486190(PRKCB)

AROW:

112975652(PRKCB)

NPD:	112959897(PRKCB)

TGT:	104573959(PRKCB)

DNE:	112985376(PRKCB)

SCAM:

104139169(PRKCB)

ASN:	102368878(PRKCB)

AMJ:	102572486(PRKCB)

CPOO:

109314792(PRKCB)

GGN:	109294289(PRKCB)

PSS:	102449325(PRKCB)

CMY:	102942074(PRKCB)

CCAY:

125643497(PRKCB)

DCC:	119862602(PRKCB)

CPIC:

101951581(PRKCB)

TST:	117884391(PRKCB)

CABI:

116818245(PRKCB)

MRV:	120372765(PRKCB)

ACS:	100565082 103281881

ASAO:

132781913(PRKCB)

PVT:	110085019(PRKCB)

SUND:

121937565(PRKCB)

PBI:	103052622 103067105

PMUR:

107285104(PRKCB)

CTIG:

120310838(PRKCB)

TSR:

106544999

PGUT:

117667323(PRKCB)

APRI:

131185074(PRKCB)

PTEX:

113438611(PRKCB)

NSS:	113423120(PRKCB)

VKO:	123034854(PRKCB)

PMUA:

114583925(PRKCB)

PRAF:

128402084(PRKCB)

ZVI:	118092573(PRKCB)

HCG:	128336440(PRKCB)

GJA:

107106337

STOW:

125432066(PRKCB)

EMC:	129340241(PRKCB)

XLA:	108701647 108703204

XTR:	100038043(prkcb)

NPR:	108791355(PRKCB)

RTEM:

120943296(PRKCB)

BBUF:

121009043(PRKCB)

BGAR:

122945749(PRKCB)

MUO:	115475655(PRKCB)

GSH:	117345607(PRKCB)

DRE:	100006675(prkcba) 393953(prkcbb)

SRX:	107710001 107722959 107725358(prkcb) 107752983

SANH:

107688094 107689613 107692661(prkcb) 107702530

SGH:	107564527(prkcb) 107590404 107590741 107601253

CCAR:

109052512 109074589 109093640

CAUA:

113044532 113044866 113047295 113070457 113079629 113093357

CGIB:

127948834 127950904 127952901 127985525

PTET:

122337000(prkcbb) 122346931(prkcba)

LROH:

127160219(prkcbb) 127163312(prkcba)

OMC:	131536620(prkcbb) 131539492(prkcba)

PPRM:

120462903(prkcba) 120489096(prkcbb)

RKG:	130075873(prkcbb) 130096866(prkcba)

MAMB:

125271228(prkcbb) 125272719(prkcba)

CIDE:

127509047 127525757

CERY:

137017725(prkcbb) 137033110(prkcba)

MASI:

127443500 127445425 127451031 127451229

TROS:

130552482(prkcba) 130560997(prkcbb)

TDW:	130425692(prkcbb) 130439103(prkcba)

MANU:

129434304(prkcbb) 129444971(prkcba)

IPU:	108258960(prkcba) 108260780(prkcbb)

IFU:	128601966(prkcba) 128622033(prkcbb)

PHYP:

113528126 113535689

SMEO:

124378066 124396752(prkcbb)

TFD:	113640400(prkcba) 113659158(prkcbb)

TVC:	132839183(prkcba) 132861454(prkcbb)

TRN:	134300151 134329331(prkcba)

AMEX:

103025973(prkcbb) 103036012(prkcba)

CMAO:

118802149(prkcba) 118821144(prkcbb)

EEE:	113580901 113588773 113590761

CHAR:

105899995 105905767(prkcba)

TRU:	101065234 101079815(prkcb)

TFS:	130514472 130528085

TNG:	GSTEN00009847G001 GSTEN00021867G001

LCO:	104917655(prkcb) 104929965

NCC:	104965314 104967427(prkcb)

TBEN:

117481636 117492333

CGOB:

115012036(prkcb) 115017865

PGEO:

117447993 117451436

GACU:

117551971 117556109

EMAC:

134864323 134877800

ELY:	117254945 117268140

EFO:	125878776 125885732

PLEP:

121941709 121957205(prkcbb)

SLUC:

116057228 116065376

ECRA:

117954179 117957402

ESP:	116703070(prkcb) 116705456

PFLV:

114566211 114569627(prkcb)

GAT:	120825887 120828414

PPUG:

119217370 119220027

AFB:	129095247 129099170

CLUM:

117734944 117749433

PSWI:

130188608 130190241

MSAM:

119885905(prkcbb) 119898769

SCHU:

122874066

CUD:	121508856 121529326

ALAT:

119014168 119017686

MZE:	101465488(prkcb) 101478005

ONL:	100703205 100710878(prkcb)

OAU:	116311412(prkcbb) 116312377

OLA:	101161464 105353642(prkcb)

OML:	112137352 112146120

CSAI:

133422491 133441753

XMA:	102228928 102235758(prkcb)

XCO:	114145501 114159895(prkcb)

XHE:	116719433 116735978(prkcb)

PRET:

103462977 103468586(prkcb)

PFOR:

103129836 103147426(prkcb)

PLAI:

106939953 106947619(prkcb)

PMEI:

106911025 106915220(prkcb)

GAF:	122822281(prkcbb) 122829859

PPRL:

129353719 129363217(prkcbb)

CVG:	107086424 107093530(prkcb)

CTUL:

119780330(prkcbb) 119783658

GMU:	124862727 124864744 124868119

NFU:	107376405(prkcb) 107388621

KMR:	108230652 108236219(prkcbb)

ALIM:

106516520 106519663

NWH:	119421112 119422362

AOCE:

111581447 111586813

MCEP:

124997521(prkcbb) 125003616

CSEM:

103383625 103393234(prkcb)

POV:	109638270 109639494

SSEN:

122770953 122784934(prkcbb)

HHIP:

117764914 117765891

HSP:	118121712 118123258

PPLT:

128432556 128459122

SMAU:

118288691 118312926

LCF:	108881079(prkcbb) 108888464

SDU:	111216674 111230195(prkcb)

SLAL:

111647517 111663270

XGL:	120788166(prkcbb) 120799866

HCQ:	109511124 109514913

SSCV:

125969131 125983525

SBIA:

133505949 133514154(prkcbb)

PEE:	133403675 133414687(prkcbb)

PTAO:

133466239(prkcbb) 133477257

BPEC:

110153511 110155785(prkcb)

MALB:

109958847(prkcb) 109968203

BSPL:

114852795 114860819

SJO:	128378636 128380002

SASA:

106563990 106563994 106593748 106594520

STRU:

115181935 115182231

OTW:	121844131 121845244

OMY:	110498604 110510730 110515515 118947071

OGO:	124017080 124021143

OKI:

116366449

OKE:	127921846 127929301

SNH:

120042471

CCLU:

121557030 121561893

ELS:	105009402 105030718(prkcb)

SFM:	108927032 108937416

PKI:	111845521 111849289

AANG:

118216704 118220309

LOC:	102689943(prkcb)

PSPA:

121300719 121331034

ARUT:

117418057 117431125

PSEX:

120542651(prkcba)

LCM:	102364971(PRKCB)

CMK:	103186617(prkcba)

CPLA:

122560735(prkcba)

HOC:

LERI:

LRJ:

LPIC:

AJC:

SKO:

DSI:	Dsimw501_GD11232(Dsim_GD11232)

DSR:

DPO:

DPE:

DWI:

DMO:	Dmoj_GI21162

DHE:

111592669

MDE:

101894312

LCQ:

111684370

CBR:	CBG_21090 CBG_21094

GAE:

HRJ:

MCAF:

MMER:

OVI:	T265_00253

EGL:

LLON:

NVE:

XEN:

MBR:	MONBRDRAFT_31267

SRE:	PTSG_09611

» show all

Reference

PMID:12070292

Authors

Saijo K, Mecklenbrauker I, Santana A, Leitger M, Schmedt C, Tarakhovsky A

Title

Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha.

Journal

J Exp Med 195:1647-52 (2002)
DOI:10.1084/jem.20020408

Sequence

[hsa:5579]

Reference

PMID:3666134

Authors

Kubo K, Ohno S, Suzuki K

Title

Primary structures of human protein kinase C beta I and beta II differ only in their C-terminal sequences.

Journal

FEBS Lett 223:138-42 (1987)
DOI:10.1016/0014-5793(87)80524-0

Reference

PMID:3755548

Authors

Coussens L, Parker PJ, Rhee L, Yang-Feng TL, Chen E, Waterfield MD, Francke U, Ullrich A

Title

Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.

Journal

Science 233:859-66 (1986)
DOI:10.1126/science.3755548

Sequence

[hsa:5579]

All links

Ontology (4)   
   KEGG BRITE (3)   
   GO (1)   
Pathway (142)   
   KEGG PATHWAY (142)   
Drug (6)   
   KEGG DRUG (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (1454)   
   KEGG GENES (546)   
   KEGG MGENES (152)   
   RefGene (745)   
   OC (11)   
Literature (3)   
   PubMed (3)   
All databases (1610)   

Download RDF

ORTHOLOGY: K02677

Entry

K02677                      KO

Symbol

PRKCA

Name

classical protein kinase C alpha type [EC:2.7.11.13]

Pathway

map01521

EGFR tyrosine kinase inhibitor resistance

map04010

MAPK signaling pathway

map04011

MAPK signaling pathway - yeast

map04012

ErbB signaling pathway

map04014

Ras signaling pathway

map04015

Rap1 signaling pathway

map04020

Calcium signaling pathway

map04066

HIF-1 signaling pathway

map04070

Phosphatidylinositol signaling system

map04071

Sphingolipid signaling pathway

map04072

Phospholipase D signaling pathway

map04139

Mitophagy - yeast

map04150

mTOR signaling pathway

map04151

PI3K-Akt signaling pathway

map04261

Adrenergic signaling in cardiomyocytes

map04270

Vascular smooth muscle contraction

map04310

Wnt signaling pathway

map04360

Axon guidance

map04370

VEGF signaling pathway

map04510

Focal adhesion

map04540

Gap junction

map04613

Neutrophil extracellular trap formation

map04650

Natural killer cell mediated cytotoxicity

map04664

Fc epsilon RI signaling pathway

map04666

Fc gamma R-mediated phagocytosis

map04670

Leukocyte transendothelial migration

map04713

Circadian entrainment

map04720

Long-term potentiation

map04723

Retrograde endocannabinoid signaling

map04724

Glutamatergic synapse

map04725

Cholinergic synapse

map04726

Serotonergic synapse

map04727

GABAergic synapse

map04728

Dopaminergic synapse

map04730

Long-term depression

map04745

Phototransduction - fly

map04750

Inflammatory mediator regulation of TRP channels

map04911

Insulin secretion

map04912

GnRH signaling pathway

map04916

Melanogenesis

map04918

Thyroid hormone synthesis

map04919

Thyroid hormone signaling pathway

map04921

Oxytocin signaling pathway

map04925

Aldosterone synthesis and secretion

map04926

Relaxin signaling pathway

map04928

Parathyroid hormone synthesis, secretion and action

map04929

GnRH secretion

map04933

AGE-RAGE signaling pathway in diabetic complications

map04935

Growth hormone synthesis, secretion and action

map04960

Aldosterone-regulated sodium reabsorption

map04961

Endocrine and other factor-regulated calcium reabsorption

map04970

Salivary secretion

map04971

Gastric acid secretion

map04972

Pancreatic secretion

map05017

Spinocerebellar ataxia

map05022

Pathways of neurodegeneration - multiple diseases

map05031

Amphetamine addiction

map05032

Morphine addiction

map05110

Vibrio cholerae infection

map05143

African trypanosomiasis

map05146

Amoebiasis

map05161

Hepatitis B

map05163

Human cytomegalovirus infection

map05164

Influenza A

map05170

Human immunodeficiency virus 1 infection

map05171

Coronavirus disease - COVID-19

map05200

Pathways in cancer

map05205

Proteoglycans in cancer

map05206

MicroRNAs in cancer

map05207

Chemical carcinogenesis - receptor activation

map05214

Glioma

map05223

Non-small cell lung cancer

map05225

Hepatocellular carcinoma

map05231

Choline metabolism in cancer

map05415

Diabetic cardiomyopathy

map05417

Lipid and atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04011 MAPK signaling pathway - yeast
    K02677  PRKCA; classical protein kinase C alpha type
   04012 ErbB signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04014 Ras signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04015 Rap1 signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04310 Wnt signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04370 VEGF signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04066 HIF-1 signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04020 Calcium signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04070 Phosphatidylinositol signaling system
    K02677  PRKCA; classical protein kinase C alpha type
   04072 Phospholipase D signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04071 Sphingolipid signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04151 PI3K-Akt signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04150 mTOR signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
09140 Cellular Processes
  09141 Transport and catabolism
   04139 Mitophagy - yeast
    K02677  PRKCA; classical protein kinase C alpha type
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K02677  PRKCA; classical protein kinase C alpha type
   04540 Gap junction
    K02677  PRKCA; classical protein kinase C alpha type
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K02677  PRKCA; classical protein kinase C alpha type
   04650 Natural killer cell mediated cytotoxicity
    K02677  PRKCA; classical protein kinase C alpha type
   04664 Fc epsilon RI signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04666 Fc gamma R-mediated phagocytosis
    K02677  PRKCA; classical protein kinase C alpha type
   04670 Leukocyte transendothelial migration
    K02677  PRKCA; classical protein kinase C alpha type
  09152 Endocrine system
   04911 Insulin secretion
    K02677  PRKCA; classical protein kinase C alpha type
   04929 GnRH secretion
    K02677  PRKCA; classical protein kinase C alpha type
   04912 GnRH signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04921 Oxytocin signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04926 Relaxin signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04935 Growth hormone synthesis, secretion and action
    K02677  PRKCA; classical protein kinase C alpha type
   04918 Thyroid hormone synthesis
    K02677  PRKCA; classical protein kinase C alpha type
   04919 Thyroid hormone signaling pathway
    K02677  PRKCA; classical protein kinase C alpha type
   04928 Parathyroid hormone synthesis, secretion and action
    K02677  PRKCA; classical protein kinase C alpha type
   04916 Melanogenesis
    K02677  PRKCA; classical protein kinase C alpha type
   04925 Aldosterone synthesis and secretion
    K02677  PRKCA; classical protein kinase C alpha type
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K02677  PRKCA; classical protein kinase C alpha type
   04270 Vascular smooth muscle contraction
    K02677  PRKCA; classical protein kinase C alpha type
  09154 Digestive system
   04970 Salivary secretion
    K02677  PRKCA; classical protein kinase C alpha type
   04971 Gastric acid secretion
    K02677  PRKCA; classical protein kinase C alpha type
   04972 Pancreatic secretion
    K02677  PRKCA; classical protein kinase C alpha type
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K02677  PRKCA; classical protein kinase C alpha type
   04961 Endocrine and other factor-regulated calcium reabsorption
    K02677  PRKCA; classical protein kinase C alpha type
  09156 Nervous system
   04724 Glutamatergic synapse
    K02677  PRKCA; classical protein kinase C alpha type
   04727 GABAergic synapse
    K02677  PRKCA; classical protein kinase C alpha type
   04725 Cholinergic synapse
    K02677  PRKCA; classical protein kinase C alpha type
   04728 Dopaminergic synapse
    K02677  PRKCA; classical protein kinase C alpha type
   04726 Serotonergic synapse
    K02677  PRKCA; classical protein kinase C alpha type
   04720 Long-term potentiation
    K02677  PRKCA; classical protein kinase C alpha type
   04730 Long-term depression
    K02677  PRKCA; classical protein kinase C alpha type
   04723 Retrograde endocannabinoid signaling
    K02677  PRKCA; classical protein kinase C alpha type
  09157 Sensory system
   04745 Phototransduction - fly
    K02677  PRKCA; classical protein kinase C alpha type
   04750 Inflammatory mediator regulation of TRP channels
    K02677  PRKCA; classical protein kinase C alpha type
  09158 Development and regeneration
   04360 Axon guidance
    K02677  PRKCA; classical protein kinase C alpha type
  09159 Environmental adaptation
   04713 Circadian entrainment
    K02677  PRKCA; classical protein kinase C alpha type
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K02677  PRKCA; classical protein kinase C alpha type
   05206 MicroRNAs in cancer
    K02677  PRKCA; classical protein kinase C alpha type
   05205 Proteoglycans in cancer
    K02677  PRKCA; classical protein kinase C alpha type
   05207 Chemical carcinogenesis - receptor activation
    K02677  PRKCA; classical protein kinase C alpha type
   05231 Choline metabolism in cancer
    K02677  PRKCA; classical protein kinase C alpha type
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    K02677  PRKCA; classical protein kinase C alpha type
   05214 Glioma
    K02677  PRKCA; classical protein kinase C alpha type
   05223 Non-small cell lung cancer
    K02677  PRKCA; classical protein kinase C alpha type
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K02677  PRKCA; classical protein kinase C alpha type
   05161 Hepatitis B
    K02677  PRKCA; classical protein kinase C alpha type
   05171 Coronavirus disease - COVID-19
    K02677  PRKCA; classical protein kinase C alpha type
   05164 Influenza A
    K02677  PRKCA; classical protein kinase C alpha type
   05163 Human cytomegalovirus infection
    K02677  PRKCA; classical protein kinase C alpha type
  09171 Infectious disease: bacterial
   05110 Vibrio cholerae infection
    K02677  PRKCA; classical protein kinase C alpha type
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    K02677  PRKCA; classical protein kinase C alpha type
   05143 African trypanosomiasis
    K02677  PRKCA; classical protein kinase C alpha type
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    K02677  PRKCA; classical protein kinase C alpha type
   05022 Pathways of neurodegeneration - multiple diseases
    K02677  PRKCA; classical protein kinase C alpha type
  09165 Substance dependence
   05031 Amphetamine addiction
    K02677  PRKCA; classical protein kinase C alpha type
   05032 Morphine addiction
    K02677  PRKCA; classical protein kinase C alpha type
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    K02677  PRKCA; classical protein kinase C alpha type
   05415 Diabetic cardiomyopathy
    K02677  PRKCA; classical protein kinase C alpha type
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    K02677  PRKCA; classical protein kinase C alpha type
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    K02677  PRKCA; classical protein kinase C alpha type
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K02677  PRKCA; classical protein kinase C alpha type
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K02677  PRKCA; classical protein kinase C alpha type
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     K02677  PRKCA; classical protein kinase C alpha type
Protein kinases [BR:ko01001]
Serine/threonine kinases: AGC group
  PKC family [OT]
   K02677  PRKCA; classical protein kinase C alpha type
Membrane trafficking [BR:ko04131]
Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    K02677  PRKCA; classical protein kinase C alpha type

Other DBs

COG:

COG0515

GO:

0004697

Genes

HSA:	5578(PRKCA)

PTR:	454832(PRKCA)

PPS:	100967981(PRKCA)

GGO:	101124828(PRKCA)

PON:	100434355(PRKCA)

PPYG:

129018207(PRKCA)

NLE:	100591651(PRKCA)

HMH:	116483969(PRKCA)

SSYN:

129462898(PRKCA)

MCC:	718412(PRKCA)

MCF:	102135875(PRKCA)

MTHB:

126938340

MNI:	105469029(PRKCA)

CSAB:

103243171(PRKCA)

CATY:

105599331(PRKCA)

PANU:

101016532(PRKCA)

TGE:	112609643(PRKCA)

MLEU:

105548239(PRKCA)

RRO:	104675428(PRKCA)

RBB:	108517746(PRKCA)

TFN:	117067396(PRKCA)

PTEH:

111542503(PRKCA)

CANG:

105503488(PRKCA)

CJC:	100391814(PRKCA)

SBQ:	101046010(PRKCA)

CIMI:

108281637(PRKCA)

ANAN:

105718208(PRKCA)

CSYR:

103269994(PRKCA)

MMUR:

105861618(PRKCA)

LCAT:

123621118(PRKCA)

PCOQ:

105820421(PRKCA)

OGA:	100965377(PRKCA)

MMU:	18750(Prkca)

MCAL:

110304357(Prkca)

MPAH:

110332714(Prkca)

RNO:	24680(Prkca)

MCOC:

116076783(Prkca)

ANU:	117709948(Prkca)

MUN:	110555335(Prkca)

CGE:	100766006(Prkca)

MAUA:

101837515(Prkca)

PROB:

127218483(Prkca)

PLEU:

114690439(Prkca)

MORG:

121436286(Prkca)

MFOT:

126514970

AAMP:

119812144(Prkca)

NGI:	103742202(Prkca)

HGL:	101716044(Prkca)

CPOC:

100713627(Prkca)

CCAN:

109687351(Prkca)

DORD:

106003156(Prkca)

DSP:	122128350(Prkca)

PLOP:

125366443(Prkca)

NCAR:

124979014

MMMA:

107158309(Prkca)

OCU:	100037720(PRKCA)

OPI:	101523549(PRKCA)

TUP:	102495954(PRKCA)

GVR:	103599847(PRKCA)

CFA:	490904(PRKCA)

CLUD:

112652873(PRKCA)

VVP:	112920728(PRKCA)

VLG:	121473288(PRKCA)

NPO:	129494612(PRKCA)

AML:	100477326(PRKCA)

UMR:	103665907(PRKCA)

UAH:	113265250(PRKCA)

UAR:	123803224(PRKCA)

ELK:

111158087

LLV:

125087644

MPUF:

101679339(PRKCA)

MNP:	132003742(PRKCA)

MLK:	131815964(PRKCA)

NVS:	122906063(PRKCA)

ORO:	101386060(PRKCA)

EJU:	114196710(PRKCA)

ZCA:	113939477(PRKCA)

MLX:	118024347(PRKCA)

NSU:	110570410(PRKCA)

FCA:	101086433(PRKCA)

PYU:	121015308(PRKCA)

PCOO:

112864470(PRKCA)

PBG:	122485801(PRKCA)

PVIV:

125151135(PRKCA)

LRUF:

124513500

PTG:	102968590(PRKCA)

PPAD:

109277056(PRKCA)

PUC:

125927372

AJU:

106975306

HHV:	120234190(PRKCA)

BTA:	282001(PRKCA)

BOM:	102278724(PRKCA)

BIU:	109573366(PRKCA)

BBUB:

102415611(PRKCA)

BBIS:

105000525(PRKCA)

CHX:	102180890(PRKCA)

OAS:	101110074(PRKCA)

BTAX:

128065393(PRKCA)

ODA:	120866588(PRKCA)

CCAD:

122424748(PRKCA)

MBEZ:

129544793(PRKCA)

SSC:	397184(PRKCA)

CFR:	102507832(PRKCA)

CBAI:

105063941(PRKCA)

CDK:	105092299(PRKCA)

VPC:	102541926(PRKCA)

BACU:

103004532(PRKCA)

BMUS:

118886504(PRKCA)

LVE:	103073028(PRKCA)

OOR:	101276350(PRKCA)

DLE:	111182917(PRKCA)

PCAD:

102974888(PRKCA)

PSIU:

116745476(PRKCA)

NASI:

112410312(PRKCA)

ECB:	100063318(PRKCA)

EAI:	106835567(PRKCA)

MYB:	102260557(PRKCA)

MYD:	102765661(PRKCA)

MMYO:

118671569(PRKCA)

MLF:	102438932(PRKCA)

MDT:	132218608(PRKCA)

PKL:	118726595(PRKCA)

EFUS:

103293119(PRKCA)

MNA:	107538300(PRKCA)

DRO:	112316515(PRKCA)

SHON:

119003729(PRKCA)

AJM:	119036326(PRKCA)

PDIC:

114502829(PRKCA)

PHAS:

123817558(PRKCA)

MMF:	118633872(PRKCA)

PPAM:

129070225(PRKCA)

HAI:	109380289(PRKCA)

RFQ:	117012818(PRKCA)

PALE:

102887078(PRKCA)

PGIG:

120600384(PRKCA)

PVP:	105297702(PRKCA)

RAY:	107510307(PRKCA)

MJV:	108387768(PRKCA)

TOD:	119231758(PRKCA)

SARA:

101551961(PRKCA)

SETR:

126017297(PRKCA)

LAV:	100665537(PRKCA)

TMU:

101348250

ETF:	101638289(PRKCA)

DNM:	101447838(PRKCA)

MDO:	100024674(PRKCA)

GAS:	123245333(PRKCA)

SHR:	100913337(PRKCA)

AFZ:

127560569

PCW:	110218307(PRKCA)

TVP:	118849188(PRKCA)

OAA:	100079107(PRKCA)

GGA:	417430(PRKCA)

PCOC:

116232465(PRKCA)

MGP:	100541727(PRKCA)

CJO:	107322193(PRKCA)

TPAI:

128083108(PRKCA)

LMUT:

125702349(PRKCA)

NMEL:

110407228(PRKCA)

APLA:

101802546(PRKCA)

ACYG:

106034675(PRKCA)

CATA:

118253863(PRKCA)

AFUL:

116496571(PRKCA)

TGU:	100219195(PRKCA)

LSR:	110474104(PRKCA)

SCAN:

103819765(PRKCA)

PMOA:

120505424(PRKCA)

OTC:	121338479(PRKCA)

PRUF:

121363372(PRKCA)

GFR:	102043485(PRKCA)

FAB:	101810891(PRKCA)

OMA:	130260381(PRKCA)

PHI:	102100311(PRKCA)

PMAJ:

107212334(PRKCA)

CCAE:

111937433(PRKCA)

CCW:	104696032(PRKCA)

CBRC:

103620084(PRKCA)

ETL:	114060678(PRKCA)

ZAB:

102068394

ZLE:	135455217(PRKCA)

ACHL:

103804704

SVG:	106856952(PRKCA)

MMEA:

130575162(PRKCA)

HRT:	120760797(PRKCA)

SATI:

136369494(PRKCA)

FPG:	101914699(PRKCA)

FCH:	102053069(PRKCA)

CCRI:

104168796

NNT:

104408442

SHAB:

115616723(PRKCA)

ACUN:

113486719(PRKCA)

TALA:

104362523(PRKCA)

ACHC:

115341437(PRKCA)

HALD:

104313281

HLE:	104838714(PRKCA)

AGEN:

GCL:

CSTI:

LDI:

MNB:

DPUB:

104302207(PRKCA)

AVIT:

104276351

BRHI:

104493344

EGZ:	104129413(PRKCA)

NNI:	104014361(PRKCA)

PCRI:

104033866

PCAO:

104046651

PADL:

103916720(PRKCA)

AFOR:

103902452(PRKCA)

FGA:

104075855

GSTE:

104258457

CLV:	102084059(PRKCA)

MUI:

PGUU:

PLET:

EHS:

CMAC:

CUCA:

104061975(PRKCA)

TEO:

104375480

BREG:

104633825

OHA:	104332942(PRKCA)

ACAR:

104530578

CPEA:

104393313(PRKCA)

CVF:	104295097(PRKCA)

RTD:	128917842(PRKCA)

AAM:	106493092(PRKCA)

AROW:

112966930(PRKCA)

NPD:	112953760(PRKCA)

TGT:	104572607(PRKCA)

DNE:	112982493(PRKCA)

SCAM:

104146830(PRKCA)

ASN:	102377784(PRKCA)

AMJ:	102572836(PRKCA)

PSS:	102459336(PRKCA)

CMY:	102941618(PRKCA)

CCAY:

125621080(PRKCA)

DCC:	119842981(PRKCA)

CPIC:

101949360(PRKCA)

TST:	117887796(PRKCA)

CABI:

116822411(PRKCA)

MRV:	120383347(PRKCA)

ACS:	100554897(prkca)

ASAO:

132767769(PRKCA)

PVT:	110088714(PRKCA)

SUND:

121924105(PRKCA)

PBI:	103057756(PRKCA)

CTIG:

120300008(PRKCA)

TSR:

106538799

PGUT:

117662922(PRKCA)

APRI:

131189703(PRKCA)

PTEX:

113443192(PRKCA)

NSS:	113419423(PRKCA)

VKO:	123033095(PRKCA)

PMUA:

114588142(PRKCA)

PRAF:

128407243(PRKCA)

ZVI:	118079639(PRKCA)

HCG:	128345840(PRKCA)

STOW:

125427662(PRKCA)

EMC:	129328100(PRKCA)

XLA:	108702159(prkca.S) 447031(prkca.L)

XTR:	780209(prkca)

RTEM:

120919232(PRKCA)

BBUF:

121004965(PRKCA)

BGAR:

122923186

MUO:	115473473(PRKCA)

GSH:	117367615(PRKCA)

DRE:	100333967(si:ch73-374l24.1) 497384(prkcaa)

SRX:	107710161 107710697 107716883

SANH:

107664393 107694902 107698783

SGH:	107556610 107569462 107586338

CCAR:

109053860 109078077

CAUA:

113047101 113049910 113053289 113097507

CGIB:

127944331 127953362 127959456 128015459

PTET:

122334878 122346932(prkcaa)

LROH:

127163386(prkcab) 127166764(prkcaa)

OMC:	131535943(prkcab) 131542168(prkcaa)

PPRM:

120466805 120481535(si:ch73-374l24.1)

RKG:	130084493(prkcab)

MAMB:

125268438(prkcab) 125274046(prkcaa)

CIDE:

127508774 127514577

CERY:

137010730(prkcaa) 137018000(prkcab)

MASI:

127449253 127450329 127452151

TROS:

130561027(prkcab)

TDW:	130426945(prkcab)

MANU:

129427148(prkcab)

IPU:	108259727(prkcab) 108273127(prkcaa)

IFU:	128615331(prkcaa) 128625389(prkcab)

PHYP:

113527932 113538454(prkca)

SMEO:

124392586(prkcaa) 124397127(prkcab)

TFD:	113634425(prkcaa) 113639499(prkcab)

TVC:	132844847(prkcaa) 132860690(prkcab)

TRN:	134300409(prkcab) 134317114(prkcaa)

AMEX:

103044047(prkcaa) 111192909(prkcab)

CMAO:

118807929(prkcaa) 118820893(si:ch73-374l24.1)

EEE:

113575317

CHAR:

105892049(prkcab) 105900227(prkcaa)

TRU:	101064815(prkca) 101071034

TFS:	130514892(prkcab) 130527887

LCO:	104918810 104927125(prkca)

NCC:	104952470(prkca)

TBEN:

117474546(prkcaa) 117492635(si:ch73-374l24.1)

CGOB:

115010783 115011646

PGEO:

117441773(prkcaa) 117451160(si:ch73-374l24.1)

GACU:

117548684(si:ch73-374l24.1) 117561994(prkcaa)

EMAC:

134865204(prkcaa) 134877835(prkcab)

ELY:	117255414(prkcaa) 117268354(si:ch73-374l24.1)

EFO:	125880136(prkcab) 125883763(prkcaa)

PLEP:

121941841(prkcaa) 121956776(prkcab)

SLUC:

116043004(prkcaa) 116059398(si:ch73-374l24.1)

ECRA:

117937306(prkcaa) 117957906(si:ch73-374l24.1)

ESP:	116670566(prkca) 116702478

PFLV:

114565339(prkca) 114570388

GAT:	120825380(prkcaa) 120828293(prkcab)

PPUG:

119218609(prkcaa) 119220222(si:ch73-374l24.1)

AFB:	129096510(prkcaa) 129097995(prkcab)

CLUM:

117733655(prkcaa) 117735288(si:ch73-374l24.1)

PSWI:

130188951(prkcab) 130189644

MSAM:

119889216(si:ch73-374l24.1) 119899340

SCHU:

122868700(prkcab) 122873474(prkcaa)

CUD:	121503417(prkcab) 121508133(prkcaa)

ALAT:

119014663(si:ch73-374l24.1) 119019491(prkcaa)

MZE:	101464257(prkca) 101487097

ONL:	100698523 100699878(prkca)

OAU:	116311804(prkcaa) 116313040(si:ch73-374l24.1)

OLA:	101159746 101160465(prkca)

OML:	112137371(prkcaa) 112145928

CSAI:

133421516(prkcab) 133444442(prkcaa)

XMA:	102227289 102228309(prkca)

XCO:	114144259(prkca) 114159851

XHE:	116719536(prkca) 116735303

PRET:

103469320 103471309(prkca)

PFOR:

103141622 103148441(prkca)

PLAI:

106957043 106957385(prkca)

PMEI:

106909699 106924234(prkca)

GAF:	122822576(prkcab) 122829343(prkcaa)

PPRL:

129363528(prkcab) 129367238(prkcaa)

CVG:	107084715 107092514

CTUL:

119784438(prkcaa) 119798353(si:ch73-374l24.1)

GMU:	124862966 124864797 124867838

NFU:	107376518 107391584

KMR:	108239241(si:ch73-374l24.1) 108247229(prkcaa)

ALIM:

106518739 106534248(prkcb)

NWH:	119421632 119422396(prkcaa)

AOCE:

111576423(prkca)

MCEP:

124997961(prkcab) 125004243(prkcaa)

CSEM:

103383975(prkca)

POV:	109627602(prkca)

SSEN:

122771238 122785514(prkcab)

HHIP:

117765921(si:ch73-374l24.1) 117765927(prkcaa)

HSP:	118117698 118123848(prkcab)

PPLT:

128436790 128458254(prkcab)

SMAU:

118288352(prkcab) 118312253(prkcaa)

LCF:	108875758(prkcaa) 108879534(prkcab)

SDU:	111227115 111236289(prkca)

SLAL:

111659692 111667575

XGL:	120787229(prkcab) 120799859(prkcaa)

HCQ:	109515231 109519811(prkca)

SSCV:

125968359 125983214

SBIA:

133505775(prkcaa) 133515088(prkcab)

PEE:	133404595(prkcaa) 133414406(prkcab)

PTAO:

133466213(prkcab) 133477529

BPEC:

110166265(prkca) 110167023

MALB:

109971535 109971994

BSPL:

114846545(prkcaa) 114860469(prkcab)

SJO:	128372880 128378482(prkcab)

SASA:

106564882

STRU:

115171658 115177626 115205322 115208609

OTW:	112225772 112230347 112265049

OMY:	110485978 110486800(si:ch73-374l24.1) 110486837 110493701

OGO:	123998962(prkcab) 124004184 124015685

ONE:	115103831 115103872

OKI:	109865703 109876162 109889555 116359989

OKE:	118364978 118371476 127928727

SALP:

111957424 111982249

SNH:	120032664 120065642

CCLU:

121533158 121551465 121557105(prkcab) 123483290

ELS:	105021568 105026133

SFM:	108937063 108940048(prkca)

PKI:	111843225 111848649(prkca)

AANG:

118219598

LOC:	102683741(prkca)

PSPA:

121295549 121296360

ARUT:

117423489 117424636

PSEX:

120517149

LCM:	102361415(PRKCA)

CMK:

CPLA:

HOC:

LERI:

PMRN:

LRJ:

BFO:	118421866 118428737

BBEL:

SCLV:

SPU:

ARUN:

DME:	Dmel_CG6518(inaC) Dmel_CG6622(Pkc53E)

DER:

6547961

DSE:

6609518

DSI:	Dsimw501_GD11233(Dsim_GD11233)

DYA:	Dyak_GE11630

DAN:

DSR:

DPO:

DPE:

DMN:	108160628 108160887 117190733

DWI:

6640138

DGR:	6568865 6568866

DMO:	Dmoj_GI21163

DNV:

DHE:

DVI:

CCAT:

BOD:	106614509 106617003

BDR:	105223560 105233410 109579532

RZE:	108362129 108370688 108376287 108376319

AOQ:	129243794 129243817 129243956 129244335 129245866

TDA:	119663811 119680941 119681222 119681281 119681782

MDE:

101894476

SCAC:

106096281 106096305

LCQ:

111684366

LSQ:	119605090 119605326 119605329 119605338

GFS:	119642219 119642242

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

ASUA:

CPII:

CNS:

BCOO:

AME:	406106(Pkc)

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

692526(Cpkc)

MSEX:

115442801

DPL:	KGM_206317

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:	114354859 114354875

ATRA:

GMW:

PXY:

PGW:

LGLY:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

DCI:

CLEC:

HHAL:

106689197(Pkc53E)

NLU:

111052561

HVI:

124367744

MQU:

128991569

PHU:	Phum_PHUM528520

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_326383

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

DPTE:

DFR:	124495890 124500567

CSCU:

111613091 111640734

CVS:	136969051 136985067

PTEP:

107445195 107449617

ABRU:

129968826 129983940

UDV:	129226580 129228497

SDM:

118180821

LPOL:

106469900 106473138

PMEO:

129587549

CEL:	CELE_E01H11.1(pkc-2)

CBR:	CBG_16150(Cbr-pkc-2)

CRQ:	GCK72_023287

PVUL:

PCAN:

BGT:

HRF:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

SMM:	Smp_176360

ATEN:

SPIS:

HSY:

RES:

SCE:	YBL105C(PKC1)

SEUB:

DI49_0084

SPAO:

SPAR_B00090

AGO:	AGOS_ACR191C

ERC:

Ecym_4652

KLA:	KLLA0_E06447g

KMX:	KLMA_70130(PKC1)

LTH:	KLTH0C05478g

VPO:	Kpol_520p17

ZRO:	ZYRO0F13310g

CGR:	2891315(GVI51_M09317)

NCS:	NCAS_0E03010(NCAS0E03010)

NDI:	NDAI_0E04610(NDAI0E04610)

TPF:	TPHA_0B01520(TPHA0B01520)

TBL:	TBLA_0I00910(TBLA0I00910)

TGB:	HG536_0B04180

TDL:	TDEL_0C03050(TDEL0C03050)

KAF:	KAFR_0G01080(KAFR0G01080)

KNG:	KNAG_0C04310(KNAG0C04310)

ZMK:	HG535_0B05370

SLUD:

SCDLUD_000123

DHA:	DEHA2G13904g

PIC:	PICST_81215

PGU:	PGUG_04383

SPAA:

SPAPADRAFT_141197

LEL:	PVL30_003507(PKC1)

LBG:	92208743(LODBEIA_P35470)

CAL:	CAALFM_C304470WA(PKC1)

CTP:	CTRG_02299

COT:	CORT_0C03120

CDU:	CD36_84410(PKC1)

CTEN:

18250308(PKC1)

CLU:	CLUG_03890

CLUS:

A9F13_01g02409

CAUR:

CJI96_0001014

PPA:	PAS_chr2-1_0124

PKZ:	C5L36_0B04260

BNN:	FOA43_000947

BBRX:

BRETT_003766

OPA:	HPODL_03651

YLI:	2908975(YALI2_F00786g)

SLB:	AWJ20_859(PKC1)

NCR:	NCU06544(pkc)

NTE:	NEUTE1DRAFT19420(NEUTE1DRAFT_19420)

SMP:	10803884(SMAC4_04666)

PAN:	PODANS72p033

PBEL:

QC761_608430(PKC1_2)

PPSD:

QC762_608430(PKC1_2)

PPSP:

QC763_608430(PKC1_2)

PPSA:

QC764_608430(PKC1_2)

MTM:	MYCTH_98099

CTHR:

MGR:

PPEI:

PGRI:

TMN:	UCRPA7_8126

SSCK:

SPSK_08342

FGR:	FGSG_09660

FPU:	FPSE_05940

FPOA:

FPOAC1_011989(PKC1)

FVN:	FVRRES_13057

FVR:	FVEG_06268

FOX:	FOXG_08410

NHE:	NECHADRAFT_103351

FFC:	NCS54_00230900

FKR:	NCS57_00226300

FMU:	J7337_004517(PKC1)

TRE:	TRIREDRAFT_2526(pkc1)

TATV:

25778325(TrAtP1_007384)

TASP:

90966898(PKC1)

MAW:	19248310(PKC1_3)

MAJ:

MAA_07035

MBRN:

26238082(G6M90_00g019020)

PCHM:

VFPPC_04994

CMT:

CCM_00005

AMUS:

LMH87_012252

PLJ:	28888666(PLICBS_003835)

PTKZ:

JDV02_000020(PKC1_1)

VAL:	VDBG_03477

VDA:	VDAG_09909

CHIG:

CH63R_13589

SAPO:

SAPIO_CDS7573

PFY:	PFICI_04259

SSL:	SS1G_14026

BFU:	BCIN_12g04680(Bcpkc1)

MBE:

MBM_00835

PSCO:

LY89DRAFT_75381

GLZ:	GLAREA_02843

ANI:	ANIA_00106

AFM:	AFUA_5G11970

ACT:	ACLA_014990

NFI:	NFIA_075320

AOR:	AO090120000316

ANG:	An18g02400(pkcA)

AFV:	AFLA_009533

ALUC:

AKAW2_31338A(PKC1)

ACHE:

ACHE_41220S(PKC1)

APUU:

APUU_12053A(PKC1)

PCS:	N7525_007180

PDP:	PDIP_59840

POU:	POX_d05302

TMF:	EYB26_001571

CIM:	CIMG_09206

CPW:	CPC735_016210

URE:	UREG_05250

ABE:

ARB_04376

TVE:

TRV_03166

PBL:	PAAG_02441

PBN:	PADG_05590

AJE:	HCAG_02636

BGH:	BDBG_07803

PNO:	SNOG_07073

PTE:

PTT_19155

PTRR:

6340197(PtrM4_012280)

AALT:

CC77DRAFT_772789

ARAB:

EKO05_0001672

ZTR:	MYCGRDRAFT_87605(Pkc1b)

PFJ:	MYCFIDRAFT_104873

FFU:	CLAFUR5_11277

CBET:

CB0940_07419

BCOM:

BAUCODRAFT_27875

NPA:	UCRNP2_6136

TML:	GSTUM_00001395001

SPO:	2539649(pck2) 2542293(pck1)

SOM:	SOMG_02811(pck1)

CNE:

CNC03300

CNB:

CNBC3910

CNG:	CNAG_01845

CGI:	CGB_C5150C

CDEU:

CNBG_3366

CDEP:

91084834(L203_100619)

KMG:	30166678(I203_106637)

KNE:	92178405(IAR55_001146)

TMS:	TREMEDRAFT_58957

TASA:

A1Q1_05351

CCAC:

CcaHIS019_0401620(PKC1)

PPL:	POSPLDRAFT_126101

TVS:	TRAVEDRAFT_147078

DSQ:	DICSQDRAFT_102551

SHS:	STEHIDRAFT_98078

HIR:	HETIRDRAFT_444815

PSQ:	PUNSTDRAFT_82249

ADL:	AURDEDRAFT_115756

FME:	FOMMEDRAFT_171362

GTR:	GLOTRDRAFT_130101

RSX:	RhiXN_09226

LBC:	LACBIDRAFT_309070(LbPKC1)

CCI:	CC1G_07190

ABP:	AGABI1DRAFT100325(AGABI1DRAFT_100325)

ABV:	AGABI2DRAFT152055(AGABI2DRAFT_152055)

PCUB:

JR316_0007172

MRR:	Moror_12416

E1B28_012266

SCM:	SCHCO_02614950(SCHCODRAFT_02614950)

CPUT:

CONPUDRAFT_82294

SLA:	SERLADRAFT_438936

WSE:	WALSEDRAFT_30270

WIC:	J056_001948

UMA:	UMAG_15023

SGRA:

EX895_002735

MGL:

MGL_2756

MRT:

MRET_1753

PGR:	PGTG_12641

PTRC:

PtA15_6A270

PSTR:

Pst134EA_003164 Pst134EA_031376

MLR:	MELLADRAFT_85936

RIE:	OCT59_013414

» show all

Reference

PMID:2336401

Authors

Finkenzeller G, Marme D, Hug H

Title

Sequence of human protein kinase C alpha.

Journal

Nucleic Acids Res 18:2183 (1990)
DOI:10.1093/nar/18.8.2183

Sequence

[hsa:5578]

Reference

PMID:8321321

Authors

Kolch W, Heidecker G, Kochs G, Hummel R, Vahidi H, Mischak H, Finkenzeller G, Marme D, Rapp UR

Title

Protein kinase C alpha activates RAF-1 by direct phosphorylation.

Journal

Nature 364:249-52 (1993)
DOI:10.1038/364249a0

Sequence

[hsa:5578]

Reference

PMID:22966207

Authors

Darieva Z, Han N, Warwood S, Doris KS, Morgan BA, Sharrocks AD

Title

Protein kinase C regulates late cell cycle-dependent gene expression.

Journal

Mol Cell Biol 32:4651-61 (2012)
DOI:10.1128/MCB.06000-11

Sequence

[sce:YBL105C]

All links

Ontology (6)   
   KEGG BRITE (4)   
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   COG (1)   
Pathway (152)   
   KEGG PATHWAY (152)   
Drug (3)   
   KEGG DRUG (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (3795)   
   KEGG GENES (951)   
   KEGG MGENES (409)   
   RefGene (2420)   
   OC (15)   
Literature (3)   
   PubMed (3)   
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