KEGG   ORTHOLOGY: K19793
Entry
K19793                      KO                                     

Name
mfnC
Definition
(5-formylfuran-3-yl)methyl phosphate transaminase [EC:2.6.1.108]
Pathway
ko00680  Methane metabolism
ko01100  Metabolic pathways
ko01240  Biosynthesis of cofactors
Module
M00935  Methanofuran biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09102 Energy metabolism
   00680 Methane metabolism
    K19793  mfnC; (5-formylfuran-3-yl)methyl phosphate transaminase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.108  (5-formylfuran-3-yl)methyl phosphate transaminase
     K19793  mfnC; (5-formylfuran-3-yl)methyl phosphate transaminase
Other DBs
RN: R11038
COG: COG0436
Genes
PACE: A6070_12195
PEF: A7E78_07625
DMA: DMR_45090
DGG: DGI_1983
DPG: DESPIGER_0708
DFL: DFE_0184
DCB: C3Y92_19395
DMS: E8L03_06035
DSD: GD606_15175
DEJ: AWY79_08275
PPRF: DPRO_2977(mfnC)
PSEL: GM415_08330
DSX: GD604_15970
DML: Dmul_38010(aspC3)
DAT: HRM2_10800(aspC2)
DOV: DSCO28_45510
DWD: DSCW_41700
DALK: DSCA_41500
DAX: FDQ92_12000
DBR: Deba_0092
BBE: BBR47_31990
BFM: BP422_11130
PPQ: PPSQR21_011610
LPIL: LIP_0260
SSYI: EKG83_24635
BTHO: Btheta7330_04576(patA_2)
BXY: BXY_47810
BOA: Bovatus_03826(patA_3)
DRC: G0Q07_10800
MJA: MJ_0684
MFE: Mefer_0615
MVU: Metvu_0344
MFS: MFS40622_1497
MJH: JH146_1215
MIG: Metig_0137
MBA: Mbar_A1546
MBY: MSBRM_2902
MBW: MSBRW_3183
MBAR: MSBR2_2861
MBAK: MSBR3_1827
MAC: MA_0636(aspC)
MMA: MM_1802
MMAZ: MmTuc01_1875
MMJ: MSMAS_2883
MMAC: MSMAC_1551
MVC: MSVAZ_2704
MEK: MSKOL_2708
MLS: MSLAZ_0359
METM: MSMTP_2810
MEF: MSWH1_2805
MEQ: MSWHS_2230
MSJ: MSSAC_0572
MSZ: MSSIH_0522
MSW: MSSIT_0552
MTHR: MSTHT_2208
MTHE: MSTHC_1072
MHOR: MSHOH_3582
MFZ: AOB57_004795
MMET: MCMEM_1376
MMH: Mmah_1336
MHAZ: BHR79_06985
MPY: Mpsy_0899
MZI: HWN40_04100
MHZ: Metho_0766
MCJ: MCON_2279(aspC)
MHI: Mhar_2101
MPD: MCP_1841
HSL: OE_2619F(aspC3)
HDL: HALDL1_11575
HALH: HTSR_0784(aspC2)
HHSR: HSR6_0811(aspC2)
HSU: HLASF_1472(aspC5)
HSF: HLASA_1459(aspC5)
SALR: FQU85_08450
HLT: I7X12_18610
HAQ: DU484_02795
HAJ: DU500_03220
HAER: DU502_01015
HRA: EI982_12430
NAJ: B1756_18480
NAG: AArcMg_1101
NAN: AArc1_2522
 » show all
Reference
  Authors
Miller D, Wang Y, Xu H, Harich K, White RH
  Title
Biosynthesis of the 5-(Aminomethyl)-3-furanmethanol moiety of methanofuran.
  Journal
Biochemistry 53:4635-47 (2014)
DOI:10.1021/bi500615p
  Sequence
[mja:MJ_0684]

  All links  
Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (116)   
   KEGG GENES (82)   
   KEGG MGENES (31)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (131)   

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KEGG   ENZYME: 2.6.1.108
Entry
EC 2.6.1.108                Enzyme                                 

Name
(5-formylfuran-3-yl)methyl phosphate transaminase;
mfnC (gene name);
[5-(hydroxymethyl)furan-3-yl]methyl phosphate transaminase
Class
Transferases;
Transferring nitrogenous groups;
Transaminases
Sysname
L-alanine:(5-formylfuran-3-yl)methyl phosphate aminotransferase
Reaction(IUBMB)
L-alanine + (5-formylfuran-3-yl)methyl phosphate = pyruvate + [5-(aminomethyl)furan-3-yl]methyl phosphate [RN:R11038]
Reaction(KEGG)
R11038
Substrate
L-alanine [CPD:C00041];
(5-formylfuran-3-yl)methyl phosphate [CPD:C20954]
Product
pyruvate [CPD:C00022];
[5-(aminomethyl)furan-3-yl]methyl phosphate [CPD:C21068]
Comment
A pyridoxal 5'-phosphate protein. The enzyme, characterized from the archaebacterium Methanocaldococcus jannaschii, participates in the biosynthesis of the cofactor methanofuran. Requires pyridoxal 5'-phosphate.
History
EC 2.6.1.108 created 2015
Pathway
ec00680  Methane metabolism
ec01100  Metabolic pathways
Orthology
K19793  (5-formylfuran-3-yl)methyl phosphate transaminase
Genes
PACE: A6070_12195
PEF: A7E78_07625
DMA: DMR_45090
DGG: DGI_1983
DPG: DESPIGER_0708
DFL: DFE_0184
DCB: C3Y92_19395
DMS: E8L03_06035
DSD: GD606_15175
DEJ: AWY79_08275
PPRF: DPRO_2977(mfnC)
PSEL: GM415_08330
DSX: GD604_15970
DML: Dmul_38010(aspC3)
DAT: HRM2_10800(aspC2)
DOV: DSCO28_45510
DWD: DSCW_41700
DALK: DSCA_41500
DAX: FDQ92_12000
DBR: Deba_0092
BBE: BBR47_31990
BFM: BP422_11130
PPQ: PPSQR21_011610
LPIL: LIP_0260
SSYI: EKG83_24635
BTHO: Btheta7330_04576(patA_2)
BXY: BXY_47810
BOA: Bovatus_03826(patA_3)
DRC: G0Q07_10800
MJA: MJ_0684
MFE: Mefer_0615
MVU: Metvu_0344
MFS: MFS40622_1497
MJH: JH146_1215
MIG: Metig_0137
MBA: Mbar_A1546
MBY: MSBRM_2902
MBW: MSBRW_3183
MBAR: MSBR2_2861
MBAK: MSBR3_1827
MAC: MA_0636(aspC)
MMA: MM_1802
MMAZ: MmTuc01_1875
MMJ: MSMAS_2883
MMAC: MSMAC_1551
MVC: MSVAZ_2704
MEK: MSKOL_2708
MLS: MSLAZ_0359
METM: MSMTP_2810
MEF: MSWH1_2805
MEQ: MSWHS_2230
MSJ: MSSAC_0572
MSZ: MSSIH_0522
MSW: MSSIT_0552
MTHR: MSTHT_2208
MTHE: MSTHC_1072
MHOR: MSHOH_3582
MFZ: AOB57_004795
MMET: MCMEM_1376
MMH: Mmah_1336
MHAZ: BHR79_06985
MPY: Mpsy_0899
MZI: HWN40_04100
MHZ: Metho_0766
MCJ: MCON_2279(aspC)
MHI: Mhar_2101
MPD: MCP_1841
HSL: OE_2619F(aspC3)
HDL: HALDL1_11575
HALH: HTSR_0784(aspC2)
HHSR: HSR6_0811(aspC2)
HSU: HLASF_1472(aspC5)
HSF: HLASA_1459(aspC5)
SALR: FQU85_08450
HLT: I7X12_18610
HAQ: DU484_02795
HAJ: DU500_03220
HAER: DU502_01015
HRA: EI982_12430
NAJ: B1756_18480
NAG: AArcMg_1101
NAN: AArc1_2522
 » show all
Reference
1  [PMID:24977328]
  Authors
Miller D, Wang Y, Xu H, Harich K, White RH
  Title
Biosynthesis of the 5-(Aminomethyl)-3-furanmethanol moiety of methanofuran.
  Journal
Biochemistry 53:4635-47 (2014)
DOI:10.1021/bi500615p
  Sequence
[mja:MJ_0684]
Other DBs
ExplorEnz - The Enzyme Database: 2.6.1.108
IUBMB Enzyme Nomenclature: 2.6.1.108
ExPASy - ENZYME nomenclature database: 2.6.1.108
BRENDA, the Enzyme Database: 2.6.1.108

  All links  
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (114)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (82)   
   KEGG MGENES (31)   
Protein sequence (13)   
   UniProt (12)   
   SWISS-PROT (1)   
DNA sequence (5)   
   GenBank (3)   
   EMBL (2)   
Protein domain (5)   
   InterPro (5)   
All databases (149)   

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KEGG   REACTION: R11038
Entry
R11038                      Reaction                               

Name
L-alanine:(5-formylfuran-3-yl)methyl-phosphate aminotransferase
Definition
(5-Formylfuran-3-yl)methyl phosphate + L-Alanine <=> [5-(Aminomethyl)furan-3-yl]methyl phosphate + Pyruvate
Equation
Comment
(5-formylfuran-3-yl)methyl phosphate transaminase
Reaction class
RC00008  C00022_C00041
RC00048  C20954_C21068
Enzyme
Pathway
rn00680  Methane metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00935  Methanofuran biosynthesis
Orthology
K19793  (5-formylfuran-3-yl)methyl phosphate transaminase [EC:2.6.1.108]
Other DBs
RHEA: 43567

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (83)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (82)   
All databases (98)   

Download RDF
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