KEGG   ORTHOLOGY: K19982Help
Entry
K19982                      KO                                     

Name
prnD
Definition
aminopyrrolnitrin oxygenase [EC:1.14.13.-]
Pathway
ko00404  Staurosporine biosynthesis
ko01100  Metabolic pathways
ko01130  Biosynthesis of antibiotics
Module
M00790  Pyrrolnitrin biosynthesis, tryptophan => pyrrolnitrin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K19982  prnD; aminopyrrolnitrin oxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.-  
     K19982  prnD; aminopyrrolnitrin oxygenase
BRITE hierarchy
Other DBs
RN: R11107
COG: COG4638
Genes
SRR: SerAS9_4265
SRL: SOD_c39970
SRY: M621_21730
SPLY: Q5A_021585(prnD)
SRS: SerAS12_4266
SRA: SerAS13_4266
SMAF: D781_2600
SRZ: AXX16_2517
SERM: CLM71_13485
PFL: PFL_3607(prnD)
PPRC: PFLCHA0_c36480(prnD)
PPRO: PPC_3746(prnD)
PSEM: TO66_16620
BPSE: BDL_5425
BPSM: BBQ_4118
BPSU: BBN_5478
BPSD: BBX_4592
BPK: BBK_4754
BPSH: DR55_5719
BPSA: BBU_3996
BPSO: X996_5523
BUT: X994_5081
BTZ: BTL_5467
BTHA: DR62_5267
BOK: DM82_6305
BCEO: I35_7750
BAM: Bamb_4729
BCED: DM42_7276(prnD)
BCON: NL30_32785
BUB: BW23_5781
BMEC: WJ16_17195
BMX: BMS_1806
DOU: BMF77_02437(prnD)
AG: AAB97507(prnD)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Lee J, Simurdiak M, Zhao H
  Title
Reconstitution and characterization of aminopyrrolnitrin oxygenase, a Rieske N-oxygenase that catalyzes unusual arylamine oxidation.
  Journal
J Biol Chem 280:36719-27 (2005)
DOI:10.1074/jbc.M505334200
  Sequence

KEGG   REACTION: R11107Help
Entry
R11107                      Reaction                               

Definition
Aminopyrrolnitrin + 2 NADPH + 2 Oxygen + 2 H+ <=> Pyrrolnitrin + 2 NADP+ + 2 H2O
Equation
C21109 + 2 C00005 + 2 C00007 + 2 C00080 <=> C12491 + 2 C00006 + 2 C00001
Comment
three-step reaction (monooxygenation, dehydrogenation and monooxygenation again)
incomplete reaction (unidentified acceptor in dehydrogenation)
Reaction class
RC00001  C00005_C00006
RC01333  C12491_C21109
Enzyme
1.14.13.-
Pathway
rn00404  Staurosporine biosynthesis
rn01100  Metabolic pathways
rn01130  Biosynthesis of antibiotics
Module
M00790  Pyrrolnitrin biosynthesis, tryptophan => pyrrolnitrin
Orthology
K19982  aminopyrrolnitrin oxygenase [EC:1.14.13.-]

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