KEGG ORTHOLOGY: K20011

ORTHOLOGY: K20011

Entry

K20011                      KO

Symbol

PRDX3

Name

peroxiredoxin 3 [EC:1.11.1.24 1.11.1.25]

Disease

H01891

Autosomal recessive spinocerebellar ataxias

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K20011  PRDX3; peroxiredoxin 3
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.24  thioredoxin-dependent peroxiredoxin
     K20011  PRDX3; peroxiredoxin 3
    1.11.1.25  glutaredoxin-dependent peroxiredoxin
     K20011  PRDX3; peroxiredoxin 3
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K20011  PRDX3; peroxiredoxin 3

Other DBs

GO:

0008379

Genes

HSA:	10935(PRDX3)

PTR:	741184(PRDX3)

PPS:	100974719(PRDX3) 100979125

GGO:	101140314(PRDX3)

PON:	100174238(PRDX3)

PPYG:

129006082(PRDX3)

NLE:	100592143(PRDX3)

HMH:	116482967(PRDX3)

SSYN:

129465450(PRDX3)

MCC:	702882(PRDX3)

MCF:	101864898(PRDX3)

MTHB:

126962683

MNI:	105467759(PRDX3)

CSAB:

103216603(PRDX3)

CATY:

105577968(PRDX3)

PANU:

101023776(PRDX3)

TGE:	112630956(PRDX3)

MLEU:

105554562(PRDX3)

RRO:	104672233(PRDX3)

RBB:	108513855(PRDX3) 108525998

TFN:	117065984(PRDX3) 117084505

PTEH:

111550700(PRDX3)

CANG:

105503383(PRDX3)

CJC:	100399960(PRDX3)

SBQ:	101039427(PRDX3)

CIMI:

108289587(PRDX3)

ANAN:

105714180(PRDX3) 135271226

CSYR:

103275858(PRDX3)

MMUR:

105857046(PRDX3) 105859417

LCAT:

123650211(PRDX3)

PCOQ:

105808693(PRDX3)

OGA:	100949629 111724303(PRDX3)

MMU:	11757(Prdx3)

MCAL:

110285525(Prdx3)

MPAH:

110327807(Prdx3)

RNO:	64371(Prdx3)

MCOC:

116104071(Prdx3)

ANU:	117724947(Prdx3)

ASYL:

127685311(Prdx3)

MUN:	110562378(Prdx3)

CGE:	100773693(Prdx3)

MAUA:

101833806(Prdx3)

PROB:

127233339(Prdx3)

PLEU:

114686122(Prdx3)

MORG:

121454702(Prdx3)

MFOT:

126505676

AAMP:

119823578(Prdx3)

NGI:	103729286(Prdx3)

HGL:	101719189(Prdx3)

CPOC:

100716687(Prdx3)

CCAN:

109701203(Prdx3)

DORD:

105989769(Prdx3)

DSP:	122126862(Prdx3)

DMER:

138803930(Prdx3)

PLOP:

125345997(Prdx3) 125362206

NCAR:

124985481

MMMA:

107152822(Prdx3)

ITI:	101975949(Prdx3)

OCU:	100339309 100357088

OPI:	101534110(PRDX3)

TUP:	102469173 102487352(PRDX3)

GVR:	103598818(PRDX3)

CFA:	477839(PRDX3)

CLUD:

112649794 112663279 112672417(PRDX3)

VVP:	112915126(PRDX3) 112931106

VLG:	121485842(PRDX3)

NPO:	129495420 129509050 129514513 129523119(PRDX3)

AML:	100478555(PRDX3)

UMR:	103657688(PRDX3)

UAH:	113251992(PRDX3)

UAR:	123796010(PRDX3)

ELK:

111145349

LLV:

125084344

MPUF:

101691759(PRDX3)

MNP:	132016822(PRDX3)

MLK:	131830627(PRDX3)

NVS:	122901161(PRDX3) 122917464

ORO:	101363822(PRDX3)

EJU:	114223092(PRDX3)

ZCA:	113923895(PRDX3)

MLX:	118026989(PRDX3)

NSU:	110589244(PRDX3)

LWW:	102736367(PRDX3)

FCA:	101088618(PRDX3)

PYU:	121037295(PRDX3)

PCOO:

112854839(PRDX3)

PBG:	122493307(PRDX3)

PVIV:

125148320(PRDX3)

LRUF:

124507181

LGF:	123577149(PRDX3)

AJU:

106969372

PTG:	102961872(PRDX3)

PPAD:

109272974(PRDX3)

PUC:

125933468

PLEZ:

122202558(PRDX3)

HHV:	120227763 120235180(PRDX3)

BTA:	281998(PRDX3)

BOM:	102270790(PRDX3)

BIU:	109552986(PRDX3)

BBIS:

105002567(PRDX3)

CHX:	102190097(PRDX3)

OAS:	101106731(PRDX3)

BTAX:

128044531 128067802(PRDX3)

CSUM:

138070293(PRDX3)

ODA:	120873863(PRDX3)

CCAD:

122445874(PRDX3)

MREE:

136160166(PRDX3)

OVR:	110138559(PRDX3)

MBEZ:

129555305(PRDX3)

SSC:	100154143(PRDX3)

CFR:	102518808(PRDX3)

CBAI:

105080776(PRDX3)

CDK:	105104195(PRDX3)

VPC:	102538393(PRDX3)

BACU:

103005508(PRDX3)

BMUS:

118882726(PRDX3)

LVE:	103071364(PRDX3)

OOR:	101275740(PRDX3) 101280461

LALB:

132507102(PRDX3)

GMF:	115840937 115843388(PRDX3) 115863441

DDP:	132422987 132434399 132439573(PRDX3)

DLE:	111172255(PRDX3)

PCAD:

102991358(PRDX3)

PSIU:

116741735(PRDX3) 116760729

PPHC:

136135951(PRDX3)

NASI:

112406970(PRDX3)

ECB:	100058646(PRDX3)

EPZ:	103554635(PRDX3)

EAI:	106836366(PRDX3) 106841003

MYB:	102261630(PRDX3)

MYD:	102768008(PRDX3) 102770946

MMYO:

118669689(PRDX3)

MLF:	102424860(PRDX3)

MDT:	132214397(PRDX3) 132228289

MYUM:

139021691(PRDX3)

PKL:	118719539(PRDX3)

EFUS:

103288600(PRDX3) 103300694

MNA:	107532095(PRDX3)

DRO:	112300172(PRDX3)

SHON:

118996304(PRDX3)

AJM:	119040085(PRDX3)

PDIC:

114496775(PRDX3)

PHAS:

123828783(PRDX3)

MMF:	118632176(PRDX3)

PPAM:

129061778 129077211(PRDX3)

HAI:	109382974(PRDX3)

RFQ:	117036372(PRDX3)

PALE:

102893774(PRDX3)

PGIG:

120608881(PRDX3)

PVP:	105291449(PRDX3)

RAY:	107509757(PRDX3)

MJV:	108396053(PRDX3)

TOD:	119233931(PRDX3)

SARA:

101540654(PRDX3) 101554641

SFUM:

130029886(PRDX3)

SETR:

125994955(PRDX3)

LAV:	100665595(PRDX3)

TMU:

101354420

ETF:	101661796(PRDX3)

DNM:	101436157(PRDX3)

MDO:	100020372(PRDX3)

GAS:	123236297(PRDX3) 123244987

SHR:	100934999(PRDX3)

AFZ:

127551635

PCW:	110209571(PRDX3)

TVP:	118828935(PRDX3)

PBRV:

138169541(PRDX3)

MLAO:

141521222(PRDX3)

OAA:	100088874(PRDX3)

TACU:

119938702(PRDX3)

GGA:	428986(PRDX3)

PCOC:

116231579(PRDX3)

MGP:	100539513(PRDX3)

CJO:	107316180(PRDX3)

TPAI:

128077783(PRDX3)

LMUT:

125692909(PRDX3)

NMEL:

110399970(PRDX3)

APLA:

101794074(PRDX3)

ACYG:

106045201(PRDX3)

CATA:

118248515(PRDX3)

AFUL:

116491286(PRDX3)

TGU:	100226317(PRDX3)

LSR:	110470008(PRDX3)

SCAN:

103814116(PRDX3)

OTC:	121341892(PRDX3)

PRUF:

121350061(PRDX3)

ATRC:

139599119(PRDX3)

GFR:	102035589(PRDX3)

FAB:	101814414(PRDX3)

OMA:	130254660(PRDX3)

PHI:	102102674(PRDX3)

PMAJ:

107206871(PRDX3)

CCAE:

111942838 111944677(PRDX3)

CCW:	104694860(PRDX3)

CBRC:

103624020(PRDX3)

ACOE:

138112676(PRDX3)

ETL:	114060964(PRDX3)

ZAB:	102069288(PRDX3)

ZLE:	135449711(PRDX3)

ACHL:

103808160(PRDX3)

SVG:	106859480(PRDX3)

MMEA:

130582761(PRDX3)

HRT:	120756103(PRDX3)

SATI:

136363988(PRDX3)

CCIC:

134046160(PRDX3)

FPG:	101919747(PRDX3)

FCH:	102050358(PRDX3)

CCRI:

104156411(PRDX3)

NNT:	104404647(PRDX3)

SHAB:

115609060(PRDX3)

ACUN:

113481703(PRDX3)

TALA:

104369286(PRDX3)

ACHC:

115347913(PRDX3)

HALD:

104311527(PRDX3)

HLE:	104830196(PRDX3)

AGEN:

126042986

HHAR:

128147267(PRDX3)

GCL:

127017897

CSTI:

104550948(PRDX3)

LDI:	104344471(PRDX3)

MNB:	103769238(PRDX3)

DPUB:

104309122(PRDX3)

PPUS:

135175882(PRDX3)

AVIT:

104269067(PRDX3)

BRHI:

104488311(PRDX3)

EGZ:	104128613(PRDX3)

NNI:	104022390(PRDX3)

PCRI:

104034057(PRDX3)

PCAO:

104039866(PRDX3)

PADL:

103918655(PRDX3)

AFOR:

103897922(PRDX3)

FGA:	104071524(PRDX3)

GSTE:

104252273(PRDX3)

CBOY:

140655481(PRDX3)

CLV:	102095000(PRDX3)

CNIC:

135991175(PRDX3)

MUI:	104541325(PRDX3)

PGUU:

104459747(PRDX3)

PLET:

104622152(PRDX3)

EHS:	104504767(PRDX3)

CUCA:

104067796(PRDX3)

TEO:	104370688(PRDX3)

BREG:

104630556(PRDX3)

OHA:	104332357(PRDX3)

ACAR:

104527707(PRDX3)

CPEA:

104394402(PRDX3)

CVF:	104283478(PRDX3)

RTD:	128911860(PRDX3)

CRID:

134516983(PRDX3)

AAM:	106489493(PRDX3)

AROW:

112967340(PRDX3)

NPD:	112957132(PRDX3)

TGT:	104575690(PRDX3)

DNE:	112987994(PRDX3)

SCAM:

104140109(PRDX3)

ASN:	102388429(PRDX3)

AMJ:	102577294(PRDX3)

CPOO:

109323800(PRDX3)

GGN:	109287204(PRDX3)

PSS:	102461191(PRDX3)

CMY:	102943650(PRDX3)

CCAY:

125640105(PRDX3)

DCC:	119859244(PRDX3)

CPIC:

101931061(PRDX3)

TST:	117879826(PRDX3)

CABI:

116825073(PRDX3)

MRV:	120369471(PRDX3)

ACS:	100567876(prdx3)

ASAO:

132771001(PRDX3)

PVT:	110075318(PRDX3)

SUND:

121926088(PRDX3)

PBI:	103064929(PRDX3)

PMUR:

107290577(PRDX3)

CTIG:

120318967(PRDX3)

TSR:	106554277(PRDX3)

PGUT:

117678757(PRDX3)

PCAE:

139318014(PRDX3)

APRI:

131200986(PRDX3)

PTEX:

113439141(PRDX3)

NSS:	113413517(PRDX3)

VKO:	123033719(PRDX3)

PMUA:

114597436(PRDX3)

PRAF:

128414183(PRDX3)

ZVI:	118096456(PRDX3)

HCG:	128350592(PRDX3)

GJA:	107106721(PRDX3)

STOW:

125438273(PRDX3)

EMC:	129332269(PRDX3)

XLA:	444559(prdx3.S) 734674(prdx3.L)

XTR:	594996(prdx3)

NPR:

108803742

RTEM:

120946780(PRDX3)

ACAT:

141105721(PRDX3)

BBUF:

121003465(PRDX3)

DTC:	141077380(PRDX3)

PWL:	138300206(PRDX3)

MUO:	115469875(PRDX3)

GSH:	117360014(PRDX3)

DRE:	373079(prdx3)

SRX:	107711436 107733724

SANH:

107666469 107698743(prdx3)

SGH:	107585283 107602498(prdx3)

CCAR:

109087633 122139409

CAUA:

113057128 113071225

CGIB:

127970148

PTET:

122356600(prdx3)

LROH:

127174996(prdx3)

GRF:	141325409(prdx3)

OMC:	131552764(prdx3)

PPRM:

120479717(prdx3)

RKG:	130099724(prdx3)

MAMB:

125276782(prdx3)

CIDE:

127524862

CERY:

137020482(prdx3)

MASI:

127412348 127413598

TROS:

130559750(prdx3)

TDW:	130431250(prdx3)

MANU:

129416056(prdx3)

PDAB:

135787173(prdx3)

IPU:	100528928(prdx3)

IFU:	128605881(prdx3)

PHYP:

113545694(prdx3)

SMEO:

124395769(prdx3)

TFD:	113660995(prdx3)

TVC:	132847477(prdx3)

CGAR:

128528818(prdx3)

NGRA:

132889590(prdx3)

TRN:	134314601(prdx3)

AMEX:

103033576(prdx3)

CMAO:

118810628(prdx3)

EEE:	113579915(prdx3)

CHAR:

105892735(prdx3)

SPIL:

134064355(prdx3)

TRU:	101068680(prdx3)

TFS:	130533506(prdx3)

TNG:	GSTEN00037525G001

LCO:	104921870(prdx3)

NCC:	104954174(prdx3)

TBEN:

117499556(prdx3)

CGOB:

115019804(prdx3)

PGEO:

117459369(prdx3)

GACU:

117552230(prdx3)

EMAC:

134858851(prdx3)

ELY:	117248242(prdx3)

EFO:	125903937(prdx3)

PLEP:

121966896

SLUC:

116039408(prdx3)

ECRA:

117960706(prdx3)

ESP:	116675714(prdx3)

PFLV:

114571865(prdx3)

GAT:	120820251(prdx3)

PPUG:

119214366(prdx3)

AFB:	129091940(prdx3)

CLUM:

117743816(prdx3)

PSWI:

130207351(prdx3)

CANA:

137779571(prdx3)

CVE:	137884326(prdx3)

MSAM:

119917077(prdx3)

SCHU:

122884839(prdx3)

CUD:	121511392(prdx3)

SPUL:

138588170(prdx3)

LMIX:

132975979(prdx3)

ALAT:

119033327(prdx3)

ASTR:

137604194(prdx3)

MZE:	101469672(prdx3)

ONL:	100704593(prdx3)

OAU:	116318781(prdx3)

OLA:	101157243(prdx3)

OML:	112161674(prdx3)

CSAI:

133463432(prdx3)

XMA:	102226709(prdx3)

XCO:	114137637(prdx3)

XHE:	116712819(prdx3)

PRET:

103477136(prdx3)

PFOR:

103148228(prdx3)

PLAI:

106960016(prdx3)

PMEI:

106903922(prdx3)

GAF:	122842363(prdx3)

PPRL:

129352596(prdx3)

CVG:	107088551(prdx3)

CTUL:

119781067(prdx3)

GMU:	124859038(prdx3)

NFU:	107375547(prdx3)

KMR:	108228497(prdx3)

ALIM:

106510923(prdx3)

NWH:	119417455(prdx3)

AOCE:

111573124(prdx3)

EJA:	138195609(prdx3)

BFRE:

138616007(prdx3)

MCEP:

125018785(prdx3)

CSEM:

103387503(prdx3)

POV:	109633186(prdx3)

SSEN:

122781397(prdx3)

SSOE:

131473703(prdx3)

HHIP:

117775161(prdx3)

HSP:	118118723(prdx3)

PPLT:

128453257(prdx3)

SMAU:

118283291(prdx3)

LCF:	108886271 108889214

SDU:	111220762(prdx3)

SLAL:

111669568(prdx3)

XGL:	120796710(prdx3)

HCQ:	109523095(prdx3)

SSCV:

125979028(prdx3)

SBIA:

133509652(prdx3)

PEE:	133409590(prdx3)

PTAO:

133485821(prdx3)

BPEC:

110162084(prdx3)

ENY:	140351304(prdx3)

MALB:

109960292(prdx3)

BSPL:

114870722(prdx3)

SJO:	128372414(prdx3)

SSCO:

133991436(prdx3)

GMH:	115560156(prdx3)

SASA:

100194723(PRDX3) 106604727(prdx3)

STRU:

115153022 115193990

OTW:	112252780 112252817

OMY:	110502286 110526511

OGO:	124038124 124041429

ONE:	115113377 115135294

OKI:	109889787(prdx3) 109899597

OKE:	118369520 118401902

OMM:	135510847 135512472

OCLA:

139381990 139409921

SALP:

111952040 111977385

SNH:	120017529 120046473

CCLU:

121553673 121568991

ELS:	105026559(prdx3)

OEP:	134022431(prdx3)

SFM:	108925852(prdx3)

PKI:	111859166(prdx3)

AANG:

118218159(prdx3)

AROT:

135245176(prdx3)

CCOG:

133118140(prdx3)

LOC:	102683998(prdx3)

PSPA:

121326289(prdx3)

ARUT:

117417694(prdx3)

PSEX:

120521436(prdx3)

LCM:	102345673(PRDX3)

CMK:

103186538

RTP:	109939044(prdx3)

CPLA:

122561190(prdx3)

HOC:

132826291

LERI:

129704023(prdx3)

HAKA:

140715472(prdx3)

PMRN:

116941199(PRDX3)

LRJ:	133345660(PRDX3)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG5826(Prx3)

DER:

6552240

DSE:

6621082

DSI:	Dsimw501_GD20225(Dsim_GD20225)

DYA:	Dyak_GE25263

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI22813

DAZ:

108620805

DNV:

108659890

DHE:

111601535

DVI:	6630546(Prx3)

CCAT:

101450633

BOD:

106625420

BDR:

105233772

RZE:	108364216 108378863

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135955284(Prx3)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ009679

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:	408540(Tpx-3)

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108727281(Tpx-3)

CCOA:

108781256

PBAR:

105424458

VEM:

105569132

COBS:

139110137(Tpx-3)

TLN:	139813913(Tpx-3)

HST:

DQU:

CFO:

FEX:

PMEC:

138940149(Tpx-3)

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

141528266(Tpx-3)

FAS:	105265306 105273138

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124212239(Tpx-3)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

DPA:

ESIM:

EFOR:

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

115453259 119189718 119191268

DPL:	KGM_210284

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:	110374288 126056331

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

CSTB:

CFUM:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

HHAL:

NLU:

HVI:	124359733 124372468

PHU:	Phum_PHUM452340

FOC:

TPAL:

ZNE:

CSEC:

PAME:

SGRE:

BROR:

IEL:

HAMR:

FCD:

DPX:	DAPPUDRAFT_305931

DMK:

DPZ:

AFRA:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:	135198467 135198468

MRJ:

PORN:

HAZT:

EAF:

LSM:

TCF:	131884153 131893456

DSV:	119455983 119459530

RSAN:

119379172 119393815

RMP:	119172010 119175863

VDE:

VJA:

GOE:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_R07E5.2(prdx-3)

CBR:	CBG_18073(Cbr-prdx-3)

CRQ:	GCK72_010105

NAI:	NECAME_06328

BMY:	BM_BM13772(Bma-prdx-3.3) BM_BM5279(Bma-prdx-3.1) BM_BM9232(Bma-prdx-3.2)

LOA:	LOAG_02289

TSP:	Tsp_00025 Tsp_13221

HRO:	HELRODRAFT_154361

LGI:	LOTGIDRAFT_123611

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

MYI:

PMAX:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_004470.1

SHX:	MS3_00004926(PRDX3_1)

OVI:	T265_12564

EGL:

EGR_10291

LLON:

135489728

TAD:	TRIADDRAFT_37495

NCOL:

116268123

» show all

Reference

PMID:12492477

Authors

Masaki M, Ikeda A, Shiraki E, Oka S, Kawasaki T

Title

Mixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergistically.

Journal

Eur J Biochem 270:76-83 (2003)
DOI:10.1046/j.1432-1033.2003.03363.x

Sequence

[hsa:10935]

Reference

PMID:20929858

Authors

Hanschmann EM, Lonn ME, Schutte LD, Funke M, Godoy JR, Eitner S, Hudemann C, Lillig CH

Title

Both thioredoxin 2 and glutaredoxin 2 contribute to the reduction of the mitochondrial 2-Cys peroxiredoxin Prx3.

Journal

J Biol Chem 285:40699-705 (2010)
DOI:10.1074/jbc.M110.185827

Sequence

[hsa:10935]

All links

Ontology (1)   
   GO (1)   
Gene (2119)   
   MGENES (108)   
   RefGene (1999)   
   OC (12)   
All databases (2120)   

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