KEGG   ORTHOLOGY: K20078
Entry
K20078                      KO                                     

Name
staP
Definition
cytochrome P450 StaP [EC:1.13.12.-]
Pathway
ko00404  Staurosporine biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00805  Staurosporine biosynthesis, tryptophan => staurosporine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K20078  staP; cytochrome P450 StaP
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.12  With incorporation of one atom of oxygen (internal monooxygenases or internal mixed-function oxidases)
    1.13.12.-  
     K20078  staP; cytochrome P450 StaP
Other DBs
RN: R11121
COG: COG2124
Genes
SRN: A4G23_00558(bioI_2)
SCLF: BB341_29670
SAQ: Sare_2331
AG: BAC55212(staP)
Reference
  Authors
Makino M, Sugimoto H, Shiro Y, Asamizu S, Onaka H, Nagano S
  Title
Crystal structures and catalytic mechanism of cytochrome P450 StaP that produces the indolocarbazole skeleton.
  Journal
Proc Natl Acad Sci U S A 104:11591-6 (2007)
DOI:10.1073/pnas.0702946104
  Sequence

  All links  
Ontology (3)   
   KEGG BRITE (2)   
   COG (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (5)   
   KEGG GENES (4)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (18)   

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KEGG   REACTION: R11121
Entry
R11121                      Reaction                               

Definition
Chromopyrrolate + 2 Oxygen + 2 NADH + 3 H+ <=> K-252c + 2 CO2 + 3 H2O + 2 NAD+
Equation
C21125 + 2 C00007 + 2 C00004 + 3 C00080 <=> C21126 + 2 C00011 + 3 C00001 + 2 C00003
Reaction class
RC00001  C00003_C00004
RC03361  C21125_C21126
Enzyme
1.13.12.-
Pathway
rn00404  Staurosporine biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00805  Staurosporine biosynthesis, tryptophan => staurosporine
Orthology
K20077  flavin-dependent monooxygenase StaC [EC:1.13.12.-]
K20078  cytochrome P450 StaP [EC:1.13.12.-]

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (2)   
   KEGG RCLASS (2)   
Gene (10)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (8)   
All databases (28)   

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