KEGG   ORTHOLOGY: K20158
Entry
K20158                      KO                                     
Symbol
pao
Name
pseudooxynicotine dehydrogenase [EC:1.4.2.3]
Pathway
map00760  Nicotinate and nicotinamide metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Module
M00811  Nicotine degradation, pyrrolidine pathway, nicotine => succinate semialdehyde
Reaction
R10103  4-(methylamino)-1-(pyridin-3-yl)butan-1-one:c-type cytochrome oxidoreductase (methylamine releasing)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K20158  pao; pseudooxynicotine dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.4  Acting on the CH-NH2 group of donors
   1.4.2  With a cytochrome as acceptor
    1.4.2.3  pseudooxynicotine dehydrogenase
     K20158  pao; pseudooxynicotine dehydrogenase
Other DBs
COG: COG1231
Genes
PPT: PPS_4080
PMON: X969_19990
PMOT: X970_19625
PMED: E3Z27_20800
PVK: EPZ47_21950
PSJY: AA098_03980 AA098_04095 AA098_21420
PSIV: LZ023_17375
ALTR: BM528_03545
ALTB: IUA53_14070
CUK: KB879_35300
PPAI: E1956_19245
RHOJ: JVH1_17505
RHJS: OYT95_18390
AMYE: MJQ72_19620
AG: AFD54463(pao)
 » show all
Reference
PMID:22267672
  Authors
Qiu J, Ma Y, Wen Y, Chen L, Wu L, Liu W
  Title
Functional identification of two novel genes from Pseudomonas sp. strain HZN6 involved in the catabolism of nicotine.
  Journal
Appl Environ Microbiol 78:2154-60 (2012)
DOI:10.1128/AEM.07025-11
  Sequence
[ag:AFD54463]
Reference
PMID:35835223
  Authors
Choudhary V, Wu K, Zhang Z, Dulchavsky M, Barkman T, Bardwell JCA, Stull F.
  Title
The enzyme pseudooxynicotine amine oxidase from Pseudomonas putida S16 is not an oxidase, but a dehydrogenase.
  Journal
J Biol Chem 298:102251 (2022)
DOI:10.1016/j.jbc.2022.102251
  Sequence
[ppt:PPS_4080]

  All links  
Ontology (1)   
   COG (1)   
Gene (1)   
   OC (1)   
All databases (2)   

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KEGG   ENZYME: 1.4.3.24
Entry
EC 1.4.3.24       Obsolete  Enzyme                                 
Name
Transferred to 1.4.2.3
Class
Oxidoreductases;
Acting on the CH-NH2 group of donors;
With oxygen as acceptor
Comment
Transferred entry: pseudooxynicotine oxidase, now classified as EC 1.4.2.3, pseudooxynicotine dehydrogenase
History
EC 1.4.3.24 created 2012, deleted 2022

  All links  
Protein sequence (62)   
   UniProt (62)   
DNA sequence (142)   
   GenBank (69)   
   EMBL (73)   
All databases (204)   

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KEGG   REACTION: R10103
Entry
R10103                      Reaction                               
Name
4-(methylamino)-1-(pyridin-3-yl)butan-1-one:c-type cytochrome oxidoreductase (methylamine releasing)
Definition
Pseudooxynicotine + H2O + 2 Ferricytochrome c <=> 4-Oxo-1-(3-pyridyl)-1-butanone + Methylamine + 2 Ferrocytochrome c + 2 H+
Equation
C20361 + C00001 + 2 C00125 <=> C19567 + C00218 + 2 C00126 + 2 C00080
Reaction class
RC00225  C19567_C20361
RC00807  C00218_C20361
Enzyme
1.4.2.3
Pathway
rn00760  Nicotinate and nicotinamide metabolism
rn01100  Metabolic pathways
rn01120  Microbial metabolism in diverse environments
Module
M00811  Nicotine degradation, pyrrolidine pathway, nicotine => succinate semialdehyde
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.4  Acting on the CH-NH2 group of donors
   1.4.2  With a cytochrome as acceptor
    1.4.2.3
     R10103  Pseudooxynicotine + H2O + 2 Ferricytochrome c <=> 4-Oxo-1-(3-pyridyl)-1-butanone + Methylamine + 2 Ferrocytochrome c + 2 H+
Orthology
K20158  pseudooxynicotine dehydrogenase [EC:1.4.2.3]
Other DBs
RHEA: 75354

  All links  
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