KEGG   ORTHOLOGY: K20424
Entry
K20424                      KO                                     

Name
acbL
Definition
2-epi-valiolone-7-phosphate 1-reductase [EC:1.1.1.-]
Pathway
ko00525  Acarbose and validamycin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00814  Acarbose biosynthesis, sedoheptulopyranose-7P => acarbose
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00525 Acarbose and validamycin biosynthesis
    K20424  acbL; 2-epi-valiolone-7-phosphate 1-reductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.-  
     K20424  acbL; 2-epi-valiolone-7-phosphate 1-reductase
Other DBs
RN: R11243
COG: COG1063
Genes
SERA: Ser39006_003960
SERQ: CWC46_03960
CVC: BKX93_19955
MMI: MMAR_0582
MMAE: MMARE11_05390
NSR: NS506_05935
NAH: F5544_18745
NAD: NCTC11293_02221
RER: RER_54470
REY: O5Y_25940
RHB: NY08_85
RHS: A3Q41_04757(gutB_3)
SALS: SLNWT_0591
SESP: BN6_52630
ACTI: UA75_21510
ACAD: UA74_21030
ASE: ACPL_3677(acbL) ACPL_6251
 » show all
Reference
  Authors
Wehmeier UF, Piepersberg W
  Title
Biotechnology and molecular biology of the alpha-glucosidase inhibitor acarbose.
  Journal
Appl Microbiol Biotechnol 63:613-25 (2004)
DOI:10.1007/s00253-003-1477-2
  Sequence
[ase:ACPL_3677]

KEGG   REACTION: R11243
Entry
R11243                      Reaction                               

Definition
5-epi-Valiolone 7-phosphate + NADH + H+ <=> 5-epi-Valiolol 7-phosphate + NAD+
Equation
Reaction class
RC00001  C00003_C00004
RC00154  C17693_C21204
Enzyme
1.1.1.-
Pathway
rn00525  Acarbose and validamycin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00814  Acarbose biosynthesis, sedoheptulopyranose-7P => acarbose
Orthology
K20424  2-epi-valiolone-7-phosphate 1-reductase [EC:1.1.1.-]

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