KEGG   ORTHOLOGY: K20430
Entry
K20430                      KO                                     

Name
acbS
Definition
glycosyltransferase AcbS [EC:2.4.-.-]
Pathway
ko00525  Acarbose and validamycin biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00814  Acarbose biosynthesis, sedoheptulopyranose-7P => acarbose
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00525 Acarbose and validamycin biosynthesis
    K20430  acbS; glycosyltransferase AcbS
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.-  Glycosyltransferases
    2.4.-.-  
     K20430  acbS; glycosyltransferase AcbS
Other DBs
RN: R11247
COG: COG0297
CAZy: GT5
Genes
CJA: CJA_3255(gt5B)
SUR: STAUR_1376(gacS)
SGU: SGLAU_01010(gacS)
SSIA: A7J05_03475
MCAB: HXZ27_14375
ASE: ACPL_3669(acbS)
ACTS: ACWT_3541
Reference
  Authors
Zhang CS, Stratmann A, Block O, Bruckner R, Podeschwa M, Altenbach HJ, Wehmeier UF, Piepersberg W
  Title
Biosynthesis of the C(7)-cyclitol moiety of acarbose in Actinoplanes species SE50/110. 7-O-phosphorylation of the initial cyclitol precursor leads to proposal of a new biosynthetic pathway.
  Journal
J Biol Chem 277:22853-62 (2002)
DOI:10.1074/jbc.M202375200
  Sequence
[ase:ACPL_3669]

KEGG   REACTION: R11247
Entry
R11247                      Reaction                               

Definition
NDP-1-epi-valienol 7-phosphate + dTDP-4-amino-4,6-dideoxy-D-glucose <=> dTDP-acarviose-7-phosphate
Equation
Comment
unclear reaction
Reaction class
RC03400  C04268_C21208
RC03401  C21207_C21208
Enzyme
2.4.-.-
Pathway
rn00525  Acarbose and validamycin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00814  Acarbose biosynthesis, sedoheptulopyranose-7P => acarbose
Orthology
K20430  glycosyltransferase AcbS [EC:2.4.-.-]

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