KEGG   ORTHOLOGY: K20457
Entry
K20457                      KO                                     

Name
DHFS
Definition
dihydrofolate synthase [EC:6.3.2.12]
Pathway
ko00790  Folate biosynthesis
ko01100  Metabolic pathways
ko01240  Biosynthesis of cofactors
Module
M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    K20457  DHFS; dihydrofolate synthase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     K20457  DHFS; dihydrofolate synthase
Other DBs
RN: R02237
COG: COG0285
GO: 0008841
Genes
ATH: AT5G41480(GLA1)
ALY: 9306705
CRB: 17879364
CSAT: 104719816 104724515 104730143
EUS: EUTSA_v10027718mg
BRP: 103827738
BNA: 106397139 106410800
BOE: 106301878
RSZ: 108837369 108851652
THJ: 104813180
CPAP: 110823533
CIT: 102611256
TCC: 18605713
GRA: 105765472
GAB: 108478339
DZI: 111309392
EGR: 104424477
GMX: 100816933
VRA: 106765120
VAR: 108338371
VUN: 114194760
CCAJ: 109795452
CAM: 101503731
LJA: Lj2g3v3340810.2(Lj2g3v3340810.2) Lj2g3v3340810.3(Lj2g3v3340810.3) Lj2g3v3340810.4(Lj2g3v3340810.4)
ADU: 107495163
AIP: 107605238
LANG: 109354372
FVE: 101295861
RCN: 112182636
PPER: 18785518
PMUM: 103333670
PAVI: 110767141
MDM: 103439847
ZJU: 107414572
CSV: 101208344
CMO: 103503019
MCHA: 111011557
CMAX: 111483133
CMOS: 111430739
CPEP: 111810923
RCU: 8274389
JCU: 105648365
HBR: 110637511
MESC: 110618018
POP: 18105679
PEU: 105113451
JRE: 109014167
VVI: 100267405
SLY: 101257178
SPEN: 107023886
SOT: 102603442
NSY: 104211315
NTO: 104084612
NAU: 109223898
INI: 109193824
SIND: 105166726
HAN: 110905160
LSV: 111888854
CCAV: 112525652
DCR: 108196284
BVG: 104888294
SOE: 110780071
CQI: 110729225
NNU: 104592271
OSA: 9266309
OBR: 102706341
BDI: 100844013
ATS: 109780420
SBI: 8066349
ZMA: 100285263(si605087f07a) 103650558
SITA: 101772222
PDA: 103702943
EGU: 105040732
MUS: 104000831
DCT: 110094420
PEQ: 110022275
AOF: 109828889
ATR: 18424396
PPP: 112278513
CRE: CHLREDRAFT_143847(FPGS1)
MNG: MNEG_3751
APRO: F751_6837
SCE: YKL132C(RMA1) YMR113W(FOL3)
ERC: Ecym_6102
KMX: KLMA_30111(FOL3)
NCS: NCAS_0A04290(NCAS0A04290)
NDI: NDAI_0E02020(NDAI0E02020)
TPF: TPHA_0G02400(TPHA0G02400)
TBL: TBLA_0I00690(TBLA0I00690)
TDL: TDEL_0A02110(TDEL0A02110)
KAF: KAFR_0D02970(KAFR0D02970)
PIC: PICST_47181(FOL3)
CAL: CAALFM_C701280CA(CaO19.6908)
SLB: AWJ20_4428(FOL3)
NCR: NCU01337
NTE: NEUTE1DRAFT115854(NEUTE1DRAFT_115854)
MGR: MGG_06002
SSCK: SPSK_04269
MAW: MAC_04937
MAJ: MAA_03215
CMT: CCM_09601
MBE: MBM_05109
ANI: AN4384.2
ANG: ANI_1_258184(An04g01120)
ABE: ARB_02693
TVE: TRV_05429
PTE: PTT_11148
CNE: CNH02620
CNB: CNBL2660
ABP: AGABI1DRAFT109678(AGABI1DRAFT_109678)
ABV: AGABI2DRAFT187126(AGABI2DRAFT_187126)
MGL: MGL_2156
MRT: MRET_0353
MALV: MALV_00140
 » show all
Reference
  Authors
Ravanel S, Cherest H, Jabrin S, Grunwald D, Surdin-Kerjan Y, Douce R, Rebeille F
  Title
Tetrahydrofolate biosynthesis in plants: molecular and functional characterization of dihydrofolate synthetase and three isoforms of folylpolyglutamate synthetase in Arabidopsis thaliana.
  Journal
Proc Natl Acad Sci U S A 98:15360-5 (2001)
DOI:10.1073/pnas.261585098
  Sequence
[ath:AT5G41480]
Reference
  Authors
Cherest H, Thomas D, Surdin-Kerjan Y
  Title
Polyglutamylation of folate coenzymes is necessary for methionine biosynthesis and maintenance of intact mitochondrial genome in Saccharomyces cerevisiae.
  Journal
J Biol Chem 275:14056-63 (2000)
DOI:10.1074/jbc.275.19.14056
  Sequence
[sce:YMR113W]

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