KEGG   ORTHOLOGY: K20487
Entry
K20487                      KO                                     

Name
nisK, spaK
Definition
two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK [EC:2.7.13.3]
Pathway
ko02020  Two-component system
ko02024  Quorum sensing
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   02020 Two-component system
    K20487  nisK, spaK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   02024 Quorum sensing
    K20487  nisK, spaK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K20487  nisK, spaK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK
  09183 Protein families: signaling and cellular processes
   02022 Two-component system
    K20487  nisK, spaK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.13  Protein-histidine kinases
    2.7.13.3  histidine kinase
     K20487  nisK, spaK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK
Protein kinases [BR:ko01001]
 Histidine kinases
  OmpR family
   K20487  nisK, spaK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK
Two-component system [BR:ko02022]
 OmpR family
  NisK-NisR (lantibiotic biosynthesis)
   K20487  nisK, spaK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK/SpaK
Other DBs
COG: COG0642
GO: 0000155
Genes
HAXI: HAALTHF_20940n
BSS: BSUW23_16515(spaK)
BST: GYO_3687
BLI: BL01675(spaK)
BLD: BLi00316(spaK)
BLH: BaLi_c03350(spaK)
BAY: RBAM_030970
BAQ: BACAU_3123(spaK)
BYA: BANAU_3284(spaK)
BAMP: B938_15865
BAML: BAM5036_3011(spaK)
BAMA: RBAU_3232(spaK)
BAMN: BASU_3013(spaK)
BAMB: BAPNAU_3291(spaK)
BAMT: AJ82_17500
BAMY: V529_33580(spaK)
BMP: NG74_03265(creC)
BAO: BAMF_3223(spaK)
BAZ: BAMTA208_17115(spaK)
BQL: LL3_03506(spaK)
BXH: BAXH7_03494(spaK)
BQY: MUS_3696(spaK)
BAMI: KSO_003650
BAMC: U471_32120
BAMF: U722_16635
BAN: BA_3899
BAR: GBAA_3899
BAT: BAS3612
BAI: BAA_3924
BANT: A16_59170
BANR: A16R_39510
BANS: BAPAT_3735
BANV: DJ46_2602
BCZ: BCE33L4751(resE)
BNC: BCN_3589
BMYO: BG05_2745
BACP: SB24_13265
BACB: OY17_18795
BACO: OXB_0131
BACY: QF06_15205
BGY: BGLY_0320(spaK)
BEO: BEH_10555
BMD: BMD_3442
BMEG: BG04_342
GKA: GK0307
GTN: GTNG_0270(spaK)
PASA: BAOM_3715
BLEN: NCTC4824_00414(phoR_2)
SEP: SE0121
SEPP: SEB_00076
SEPS: DP17_1336
BLR: BRLA_c016240(yycG_2)
PPM: PPSC2_12980(eTR1)
PPO: PPM_2488(eTR1)
PPOY: RE92_23815
SIV: SSIL_0471
LLK: LLKF_1299(nisK)
LLT: CVCAS_0594(nisK)
LLS: lilo_0564(nisK)
LLX: NCDO2118_1266(nisK)
LLJ: LG36_0637(nisK)
SPY: SPy_1082(srtK)
SPZ: M5005_Spy0805(srtK)
SPYM: M1GAS476_0862(srtK)
SPYA: A20_0845(srtK)
SPH: MGAS10270_Spy0918(srtK)
SPI: MGAS10750_Spy0954(srtK)
SPJ: MGAS2096_Spy0878(srtK)
SPK: MGAS9429_Spy0921(srtK)
SPB: M28_Spy0780(srtK)
SMU: SMU_660
SMJ: SMULJ23_1333(spaK)
SMUA: SMUFR_0574
STC: str0902(hk04)
STL: stu0902(hk04)
STE: STER_0926
STN: STND_0875
STU: STH8232_1103(hk04)
STW: Y1U_C0972
STHE: T303_05645
SSA: SSA_0205(nisK)
SGO: SGO_1907
SEQ: SZO_05570
SEQU: Q426_02115
SEU: SEQ_1586
SGG: SGGBAA2069_c10890(srtK)
SGT: SGGB_1093(srtK)
SMB: smi_0309
STB: SGPB_1109(nsuK)
SCF: Spaf_1097(nisK) Spaf_1119(nisK2)
SSR: SALIVB_0932(hk04)
STJ: SALIVA_1179(hk04) SALIVA_2088(nisK)
SIF: Sinf_0947
SIB: SIR_0966
SIU: SII_0983
SIK: K710_0267
SLU: KE3_1028
STRG: SRT_14710
LCA: LSEI_0461
LCS: LCBD_0525
LCE: LC2W_0527
LPAP: LBPC_0428
LCB: LCABL_05270(resE)
LRH: LGG_00549(resE)
LRG: LRHM_0530
LRL: LC705_00539(resE)
LRA: LRHK_556
MPX: MPD5_0087
CTC: CTC_00598 CTC_00629(spaK)
CBA: CLB_1606(spaK) CLB_1863
CBK: CLL_A2206
CBT: CLH_2007
CBM: CBF_1973
CBE: Cbei_3321
CBZ: Cbs_3321
CBEI: LF65_03808
CKL: CKL_1290
CKR: CKR_1186
CSB: CLSA_c24470(spaK)
CBV: U729_2422
CTYK: CTK_C13820
CCOH: SAMEA4530647_0526(spaK)
AMT: Amet_3868
HHW: NCTC503_00467(phoR_1)
HSC: HVS_03100(phoR1)
CSS: Cst_c00950(yycG)
CSD: Clst_0090
CCEL: CCDG5_0814
RUM: CK1_37080
BHU: bhn_I0856
RIX: RO1_29680
CCT: CC1_02440
BPRO: PMF13cell1_02798(baeS_4) PMF13cell1_03984(cssS) PMF13cell1_05185(resE_13)
CSCI: HDCHBGLK_02145(cssS_1) HDCHBGLK_02895(creC)
BPRL: CL2_28900
CPRO: CPRO_14580(czcS)
EHL: EHLA_0766
RTO: RTO_31550
ERT: EUR_30220
ERA: ERE_02710
PHX: KGNDJEFE_01375(walK_2)
ELM: ELI_2589
TTM: Tthe_1882
TSH: Tsac_2263
PHAR: NCTC13077_00014(yycG_1)
BLN: Blon_1004
BLON: BLIJ_1024
BAST: BAST_1585
BCOR: BCOR_0499
BANG: BBAG_0989
GPA: GPA_27680
PCAT: Pcatena_14550(srtK)
CBAC: JI75_04580
SMR: Smar_1100
 » show all
Reference
PMID:8161176
  Authors
Engelke G, Gutowski-Eckel Z, Kiesau P, Siegers K, Hammelmann M, Entian KD
  Title
Regulation of nisin biosynthesis and immunity in Lactococcus lactis 6F3.
  Journal
Appl Environ Microbiol 60:814-25 (1994)
DOI:10.1128/AEM.60.3.814-825.1994
  Sequence

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