KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
K20574 kanJ, kacB; kanamycin B dioxygenase
Enzymes [BR:ko01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
1.14.11.37 kanamycin B dioxygenase
K20574 kanJ, kacB; kanamycin B dioxygenase
The last step of kanamycin biosynthesis: unique deamination reaction catalyzed by the alpha-ketoglutarate-dependent nonheme iron dioxygenase KanJ and the NADPH-dependent reductase KanK.
